Author results

2C80
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STRUCTURE OF SH28GST IN COMPLEX WITH S-HEXYL GLUTATHIONE
Descriptor:GLUTATHIONE S-TRANSFERASE 28 KDA, S-HEXYLGLUTATHIONE, TETRAETHYLENE GLYCOL
Authors:Baiocco, P., Gourlay, L.J., Angelucci, F., Bellelli, A., Brunori, M., Miele, A.E.
Deposit date:2005-11-30
Release date:2006-06-21
Last modified:2013-05-08
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Probing the Mechanism of Gsh Activation in Schistosoma Haematobium Glutathione-S-Transferase by Site-Directed Mutagenesis and X-Ray Crystallography.
J.Mol.Biol., 360, 2006
2C8U
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STRUCTURE OF R21Q MUTANT OF SH28GST
Descriptor:GLUTATHIONE S-TRANSFERASE 28 KDA, SULFATE ION, BETA-MERCAPTOETHANOL
Authors:Baiocco, P., Gourlay, L.J., Angelucci, F., Bellelli, A., Miele, A.E., Brunori, M.
Deposit date:2005-12-07
Release date:2006-06-21
Last modified:2013-05-08
Method:X-RAY DIFFRACTION (2 Å)
Cite:Probing the Mechanism of Gsh Activation in Schistosoma Haematobium Glutathione-S-Transferase by Site-Directed Mutagenesis and X-Ray Crystallography.
J.Mol.Biol., 360, 2006
2CA8
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STRUCTURE OF SH28GST IN COMPLEX WITH GSH AT PH 6.0
Descriptor:GLUTATHIONE S-TRANSFERASE 28 KDA, GLUTATHIONE, TETRAETHYLENE GLYCOL
Authors:Baiocco, P., Gourlay, L.J., Angelucci, F., Bellelli, A., Miele, A.E., Brunori, M.
Deposit date:2005-12-20
Release date:2006-06-26
Last modified:2013-04-17
Method:X-RAY DIFFRACTION (2.49 Å)
Cite:Probing the Mechanism of Gsh Activation in Schistosoma Haematobium Glutathione-S-Transferase by Site-Directed Mutagenesis and X-Ray Crystallography.
J.Mol.Biol., 360, 2006
2CAI
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STRUCTURE OF GLUTATHIONE-S-TRANSFERASE MUTANT, R21L, FROM SCHISTOSOMA HAEMATOBIUM
Descriptor:GLUTATHIONE S-TRANSFERASE 28 KDA, SULFATE ION, TETRAETHYLENE GLYCOL, ...
Authors:Baiocco, P., Gourlay, L.J., Angelucci, F., Bellelli, A., Brunori, M., Miele, A.E.
Deposit date:2005-12-21
Release date:2006-06-21
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.26 Å)
Cite:Probing the Mechanism of Gsh Activation in Schistosoma Haematobium Glutathione-S-Transferase by Site-Directed Mutagenesis and X-Ray Crystallography.
J.Mol.Biol., 360, 2006
2CAQ
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STRUCTURE OF R21L MUTANT OF SH28GST IN COMPLEX WITH GSH
Descriptor:GLUTATHIONE S-TRANSFERASE 28 KDA, GLUTATHIONE, TETRAETHYLENE GLYCOL, ...
Authors:Baiocco, P., Gourlay, L.J., Angelucci, F., Bellelli, A., Miele, A.E., Brunori, M.
Deposit date:2005-12-22
Release date:2006-06-21
Last modified:2013-05-08
Method:X-RAY DIFFRACTION (2 Å)
Cite:Probing the Mechanism of Gsh Activation in Schistosoma Haematobium Glutathione-S-Transferase by Site-Directed Mutagenesis and X-Ray Crystallography.
J.Mol.Biol., 360, 2006
2JK6
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STRUCTURE OF TRYPANOTHIONE REDUCTASE FROM LEISHMANIA INFANTUM
Descriptor:TRYPANOTHIONE REDUCTASE, FLAVIN-ADENINE DINUCLEOTIDE, SULFATE ION
Authors:Baiocco, P., Colotti, G., Franceschini, S., Ilari, A.
Deposit date:2008-08-21
Release date:2009-04-28
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.95 Å)
Cite:Molecular Basis of Antimony Treatment in Leishmaniasis.
J.Med.Chem., 52, 2009
2W0H
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X RAY STRUCTURE OF LEISHMANIA INFANTUM TRYPANOTHIONE REDUCTASE IN COMPLEX WITH ANTIMONY AND NADPH
Descriptor:TRYPANOTHIONE REDUCTASE, FLAVIN-ADENINE DINUCLEOTIDE, ANTIMONY (III) ION, ...
Authors:Baiocco, P., Colotti, G., Franceschini, S., Ilari, A.
Deposit date:2008-08-18
Release date:2009-04-28
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:Molecular Basis of Antimony Treatment in Leishmaniasis.
J.Med.Chem., 52, 2009
2X50
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CRYSTAL STRUCTURE OF TRYPANOTHIONE REDUCTASE FROM LEISHMANIA INFANTUM IN COMPLEX WITH NADPH AND SILVER
Descriptor:TRYPANOTHIONE REDUCTASE, FLAVIN-ADENINE DINUCLEOTIDE, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ...
Authors:Baiocco, P., Ilari, A., Colotti, G.
Deposit date:2010-02-03
Release date:2011-01-12
Last modified:2014-06-18
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Inhibitory Effect of Silver Nanoparticles on Trypanothione Reductase Activity and Leishmania Infantum Proliferation
Acs Med.Chem.Lett., 2, 2011
4ADW
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CRYSTAL STRUCTURE OF LEISHMANIA INFANTUM TRYPANOTHIONE REDUCTASE IN COMPLEX WITH NADPH AND TRYPANOTHIONE
Descriptor:TRYPANOTHIONE REDUCTASE, FLAVIN-ADENINE DINUCLEOTIDE, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ...
Authors:Baiocco, P., Ilari, A., Colotti, G., Malatesta, F., Fiorillo, A.
Deposit date:2012-01-04
Release date:2013-01-16
Last modified:2013-07-10
Method:X-RAY DIFFRACTION (3.61 Å)
Cite:Inhibition of Leishmania Infantum Trypanothione Reductase by Azole-Based Compounds: A Comparative Analysis with its Physiological Substrate by X-Ray Crystallography.
Chemmedchem, 8, 2013
4APN
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STRUCTURE OF TR FROM LEISHMANIA INFANTUM IN COMPLEX WITH A DIARYLPIRROLE-BASED INHIBITOR
Descriptor:TRYPANOTHIONE REDUCTASE, FLAVIN-ADENINE DINUCLEOTIDE, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ...
Authors:Baiocco, P., Ilari, A., Colotti, G., Biava, M.
Deposit date:2012-04-04
Release date:2013-04-17
Last modified:2013-07-10
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Inhibition of Leishmania Infantum Trypanothione Reductase by Azole-Based Compounds: A Comparative Analysis with its Physiological Substrate by X-Ray Crystallography.
Chemmedchem, 8, 2013
4UZV
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STRUCTURE OF A TRIPLE MUTANT OF ASV-TFTRHB
Descriptor:HEMOGLOBIN, PROTOPORPHYRIN IX CONTAINING FE, ACETATE ION
Authors:Baiocco, P., Bonamore, A., Sciamanna, N., Ilari, A., Boechi, L., Boffi, A., Smulevich, G., Feis, A.
Deposit date:2014-09-09
Release date:2014-09-17
Last modified:2014-12-03
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Role of Local Structure and Dynamics of Small Ligand Migration in Proteins: A Study of a Mutated Truncated Hemoprotein from Thermobifida Fusca by Time Resolved Mir Spectroscopy.
J.Phys.Chem.B, 118, 2014
2F8F
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CRYSTAL STRUCTURE OF THE Y10F MUTANT OF THE GLUATHIONE S-TRANSFERASE FROM SCHISTOSOMA HAEMATOBIUM
Descriptor:Glutathione S-transferase 28 kDa, GLUTATHIONE
Authors:Gourlay, L.J., Baiocco, P., Angelucci, F., Miele, A.E., Bellelli, A., Brunori, M.
Deposit date:2005-12-02
Release date:2006-07-04
Last modified:2012-03-21
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Probing the Mechanism of GSH Activation in Schistosoma haematobium Glutathione-S-transferase by Site-directed Mutagenesis and X-ray Crystallography.
J.Mol.Biol., 360, 2006
2YAU
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X-RAY STRUCTURE OF THE LEISHMANIA INFANTUM TRYOPANOTHIONE REDUCTASE IN COMPLEX WITH AURANOFIN
Descriptor:TRYPANOTHIONE REDUCTASE, FLAVIN-ADENINE DINUCLEOTIDE, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ...
Authors:Baiocco, P., Ilari, A., Colotti, G.
Deposit date:2011-02-24
Release date:2012-01-11
Last modified:2012-02-08
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:A Gold-Containing Drug Against Parasitic Polyamine Metabolism: The X-Ray Structure of Trypanothione Reductase from Leishmania Infantum in Complex with Auranofin Reveals a Dual Mechanism of Enzyme Inhibition.
Amino Acids, 42, 2012
5LS9
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HUMANIZED ARCHAEAL FERRITIN
Descriptor:Ferritin, putative, MAGNESIUM ION
Authors:Baiocco, P., Trabuco, M.C., Boffi, A.
Deposit date:2016-08-23
Release date:2016-11-30
Last modified:2017-01-18
Method:X-RAY DIFFRACTION (2.93 Å)
Cite:Humanized archaeal ferritin as a tool for cell targeted delivery.
Nanoscale, 9, 2017
5OBA
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STRUCTURE OF A MODIFIED MOUSE H-CHAIN FERRITIN WITH A LANTHANIDE BINDING MOTIF
Descriptor:Ferritin heavy chain, FE (III) ION
Authors:Baiocco, P., Trabuco, M.C.
Deposit date:2017-06-26
Release date:2018-07-25
Last modified:2018-08-22
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Engineered ferritin for lanthanide binding.
PLoS ONE, 13, 2018
5OBB
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STRUCTURE OF A MODIFIED MOUSE H CHAIN FERRITIN WITH A LANTHANIDE BINDING MOTIF IN COMPLEX WITH TERBIUM
Descriptor:Ferritin heavy chain, TERBIUM(III) ION
Authors:Baiocco, P., Trabuco, M.C.
Deposit date:2017-06-26
Release date:2018-07-25
Last modified:2018-08-22
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Engineered ferritin for lanthanide binding.
PLoS ONE, 13, 2018
1VYF
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SCHISTOSOMA MANSONI FATTY ACID BINDING PROTEIN IN COMPLEX WITH OLEIC ACID
Descriptor:14 KDA FATTY ACID BINDING PROTEIN, OLEIC ACID
Authors:Angelucci, F., Johnson, K.A., Baiocco, P., Miele, A.E., Bellelli, A.
Deposit date:2004-04-29
Release date:2004-09-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Schistosoma Mansoni Fatty Acid Binding Protein: Specificity and Functional Control as Revealed by Crystallographic Structure
Biochemistry, 43, 2004
1VYG
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SCHISTOSOMA MANSONI FATTY ACID BINDING PROTEIN IN COMPLEX WITH ARACHIDONIC ACID
Descriptor:FATTY ACID BINDING PROTEIN, ARACHIDONIC ACID
Authors:Angelucci, F., Johnson, K.A., Baiocco, P., Miele, A.E., Bellelli, A.
Deposit date:2004-04-29
Release date:2004-09-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Schistosoma Mansoni Fatty Acid Binding Protein: Specificity and Functional Control as Revealed by Crystallographic Structure
Biochemistry, 43, 2004
2XWY
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STRUCTURE OF MK-3281, A POTENT NON-NUCLEOSIDE FINGER-LOOP INHIBITOR, IN COMPLEX WITH THE HEPATITIS C VIRUS NS5B POLYMERASE
Descriptor:RNA-DIRECTED RNA POLYMERASE, (7R)-14-cyclohexyl-7-{[2-(dimethylamino)ethyl](methyl)amino}-7,8-dihydro-6H-indolo[1,2-e][1,5]benzoxazocine-11-carboxylic acid, MANGANESE (II) ION
Authors:Di Marco, S., Baiocco, P.
Deposit date:2010-11-06
Release date:2010-12-22
Last modified:2019-04-03
Method:X-RAY DIFFRACTION (2.53 Å)
Cite:Discovery of (7R)-14-Cyclohexyl-7-{[2-(Dimethylamino)Ethyl] (Methyl)Amino}-7,8-Dihydro-6H-Indolo[1,2-E][1,5] Benzoxazocine -11-Carboxylic Acid (Mk-3281), a Potent and Orally Bioavailable Finger-Loop Inhibitor of the Hepatitis C Virus Ns5B Polymerase
J.Med.Chem., 54, 2011
6GSR
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SINGLE PARTICLE CRYO-EM MAP OF HUMAN TRANSFERRIN RECEPTOR 1 - H-FERRITIN COMPLEX AT 5.5 ANGSTROM RESOLUTION.
Descriptor:Ferritin heavy chain, Transferrin receptor protein 1
Authors:Testi, C., Montemiglio, L.C., Vallone, B., Des Georges, A., Boffi, A., Mancia, F., Baiocco, P.
Deposit date:2018-06-15
Release date:2019-03-27
Last modified:2019-05-08
Method:ELECTRON MICROSCOPY (5.5 Å)
Cite:Cryo-EM structure of the human ferritin-transferrin receptor 1 complex.
Nat Commun, 10, 2019
6H5I
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SINGLE PARTICLE CRYO-EM MAP OF HUMAN TRANSFERRIN RECEPTOR 1 - H-FERRITIN COMPLEX.
Descriptor:Ferritin heavy chain, Transferrin receptor protein 1
Authors:Testi, C., Montemiglio, L.C., Vallone, B., Des Georges, A., Boffi, A., Mancia, F., Baiocco, P., Savino, C.
Deposit date:2018-07-24
Release date:2019-03-27
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Cryo-EM structure of the human ferritin-transferrin receptor 1 complex.
Nat Commun, 10, 2019
2CK1
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THE STRUCTURE OF OXIDISED CYCLOPHILIN A FROM S. MANSONI
Descriptor:PEPTIDYL-PROLYL CIS-TRANS ISOMERASE E, ACETATE ION
Authors:Gourlay, L.J., Angelucci, F., Bellelli, A., Boumis, G., Miele, A.E., Brunori, M.
Deposit date:2006-04-10
Release date:2007-05-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:The Three-Dimensional Structure of Two Redox States of Cyclophilin-A from Schistosoma Mansoni: Evidence for Redox- Regulation of Peptidyl-Prolyl Cis-Trans Isomerase Activity.
J.Biol.Chem., 282, 2007
2CMT
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THE STRUCTURE OF REDUCED CYCLOPHILIN A FROM S. MANSONI
Descriptor:PEPTIDYL-PROLYL CIS-TRANS ISOMERASE E, ACETATE ION
Authors:Gourlay, L.J., Angelucci, F., Bellelli, A., Boumis, G., Miele, A.E., Brunori, M.
Deposit date:2006-05-12
Release date:2007-05-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:The Three-Dimensional Structure of Two Redox States of Cyclophilin a from Schistosoma Mansoni. Evidence for Redox Regulation of Peptidyl-Prolyl Cis-Trans Isomerase Activity.
J.Biol.Chem., 282, 2007
3S9F
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THE STRUCTURE OF TRYPAREDOXIN I FROM LEISHMANIA MAJOR
Descriptor:Tryparedoxin, MAGNESIUM ION
Authors:Fiorillo, A., Ilari, A., Colotti, G.
Deposit date:2011-06-01
Release date:2012-06-13
Last modified:2013-01-02
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:The crystal structures of the tryparedoxin-tryparedoxin peroxidase couple unveil the structural determinants of Leishmania detoxification pathway.
Plos Negl Trop Dis, 6, 2012
3TUE
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THE STRUCTURE OF TRYPAREDOXIN PEROXIDASE I FROM LEISHMANIA MAJOR
Descriptor:Tryparedoxin peroxidase
Authors:Fiorillo, A., Ilari, A., Colotti, G.
Deposit date:2011-09-16
Release date:2012-09-05
Last modified:2012-09-12
Method:X-RAY DIFFRACTION (3 Å)
Cite:The crystal structures of the tryparedoxin-tryparedoxin peroxidase couple unveil the structural determinants of leishmania detoxification pathway.
Plos Negl Trop Dis, 6, 2012