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5D1Y
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LOW RESOLUTION CRYSTAL STRUCTURE OF HUMAN RIBONUCLEOTIDE REDUCTASE ALPHA6 HEXAMER IN COMPLEX WITH DATP
Descriptor:Ribonucleoside-diphosphate reductase large subunit
Authors:Ando, N., Li, H., Brignole, E.J., Thompson, S., McLaughlin, M.I., Page, J., Asturias, F., Stubbe, J., Drennan, C.L.
Deposit date:2015-08-04
Release date:2016-01-20
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (9.005 Å)
Cite:Allosteric Inhibition of Human Ribonucleotide Reductase by dATP Entails the Stabilization of a Hexamer.
Biochemistry, 55, 2016
5U0P
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CRYO-EM STRUCTURE OF THE TRANSCRIPTIONAL MEDIATOR
Descriptor:Mediator complex subunit 14, Mediator complex subunit 6, Mediator complex subunit 8, ...
Authors:Tsai, K.-L., Yu, X., Gopalan, S., Chao, T.-C., Zhang, Y., Florens, L., Washburn, M.P., Murakami, K., Conaway, R.C., Conaway, J.W., Asturias, F.
Deposit date:2016-11-26
Release date:2017-03-08
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (4.4 Å)
Cite:Mediator structure and rearrangements required for holoenzyme formation.
Nature, 544, 2017
5U0S
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CRYO-EM STRUCTURE OF THE MEDIATOR-RNAPII COMPLEX
Descriptor:Mediator complex subunit 6, Mediator complex subunit 8, Mediator complex subunit 17, ...
Authors:Tsai, K.-L., Yu, X., Gopalan, S., Chao, T.-C., Zhang, Y., Florens, L., Washburn, M.P., Murakami, K., Conaway, R.C., Conaway, J.W., Asturias, F.
Deposit date:2016-11-26
Release date:2017-03-08
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (7.8 Å)
Cite:Mediator structure and rearrangements required for holoenzyme formation.
Nature, 544, 2017
6AUI
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HUMAN RIBONUCLEOTIDE REDUCTASE LARGE SUBUNIT (ALPHA) WITH DATP AND CDP
Descriptor:Ribonucleoside-diphosphate reductase large subunit, 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, MAGNESIUM ION, ...
Authors:Brignole, E.J., Drennan, C.L., Asturias, F.J., Tsai, K.L., Penczek, P.A.
Deposit date:2017-09-01
Release date:2018-04-18
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:3.3- angstrom resolution cryo-EM structure of human ribonucleotide reductase with substrate and allosteric regulators bound.
Elife, 7, 2018