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4KPR
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BU of 4kpr by Molmil
Tetrameric form of rat selenoprotein thioredoxin reductase 1
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, FLAVIN-ADENINE DINUCLEOTIDE, SULFITE ION, ...
Authors:Lindqvist, Y, Sandalova, T, Xu, J, Arner, E.
Deposit date:2013-05-14
Release date:2014-05-14
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:The Trp114 residue of thioredoxin reductase 1 is an electron relay sensor for oxidative stress
To be Published, 2013
3EAO
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BU of 3eao by Molmil
Crystal structure of recombinant rat selenoprotein thioredoxin reductase 1 with oxidized C-terminal tail
Descriptor: FLAVIN-ADENINE DINUCLEOTIDE, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, Thioredoxin reductase 1, ...
Authors:Sandalova, T, Cheng, Q, Lindqvist, Y, Arner, E.
Deposit date:2008-08-26
Release date:2008-12-02
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Crystal structure and catalysis of the selenoprotein thioredoxin reductase 1.
J.Biol.Chem., 284, 2009
3EAN
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BU of 3ean by Molmil
Crystal structure of recombinant rat selenoprotein thioredoxin reductase 1 with reduced C-terminal tail
Descriptor: FLAVIN-ADENINE DINUCLEOTIDE, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, Thioredoxin reductase 1
Authors:Sandalova, T, Cheng, Q, Lindqvist, Y, Arner, E.
Deposit date:2008-08-26
Release date:2008-12-02
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Crystal structure and catalysis of the selenoprotein thioredoxin reductase 1.
J.Biol.Chem., 284, 2009
6HP9
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BU of 6hp9 by Molmil
Structure of the kinase domain of human DDR1 in complex with a 2-Amino-2,3-Dihydro-1H-Indene-5-Carboxamide-based inhibitor
Descriptor: (2~{R})-~{N}-[3-(4-methylimidazol-1-yl)-5-(trifluoromethyl)phenyl]-2-(pyrimidin-5-ylamino)-2,3-dihydro-1~{H}-indene-5-carboxamide, Epithelial discoidin domain-containing receptor 1
Authors:Pinkas, D.M, Fox, A.E, Kupinska, K, Burgess-Brown, N.A, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Bullock, A.N, Structural Genomics Consortium (SGC)
Deposit date:2018-09-19
Release date:2019-01-30
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.96 Å)
Cite:2-Amino-2,3-dihydro-1H-indene-5-carboxamide-Based Discoidin Domain Receptor 1 (DDR1) Inhibitors: Design, Synthesis, and in Vivo Antipancreatic Cancer Efficacy.
J.Med.Chem., 62, 2019

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