Author results

3FYG
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CRYSTAL STRUCTURE OF TETRADECA-(3-FLUOROTYROSYL)-GLUTATHIONE S-TRANSFERASE
Descriptor:MU CLASS TETRADECA-(3-FLUOROTYROSYL)-GLUTATHIONE S-TRANSFERASE OF ISOENZYME, (9R,10R)-9-(S-GLUTATHIONYL)-10-HYDROXY-9,10-DIHYDROPHENANTHRENE
Authors:Xiao, G., Parsons, J.F., Armstrong, R.N., Gilliland, G.L.
Deposit date:1997-08-07
Release date:1999-06-01
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Conformational changes in the crystal structure of rat glutathione transferase M1-1 with global substitution of 3-fluorotyrosine for tyrosine.
J.Mol.Biol., 281, 1998
6GST
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FIRST-SPHERE AND SECOND-SPHERE ELECTROSTATIC EFFECTS IN THE ACTIVE SITE OF A CLASS MU GLUTATHIONE TRANSFERASE
Descriptor:MU CLASS GLUTATHIONE S-TRANSFERASE OF ISOENZYME 3-3, GLUTATHIONE
Authors:Xiao, G., Ji, X., Armstrong, R.N., Gilliland, G.L.
Deposit date:1996-01-26
Release date:1996-11-08
Last modified:2011-12-07
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:First-sphere and second-sphere electrostatic effects in the active site of a class mu gluthathione transferase.
Biochemistry, 35, 1996
6GSU
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FIRST-SPHERE AND SECOND-SPHERE ELECTROSTATIC EFFECTS IN THE ACTIVE SITE OF A CLASS MU GLUTATHIONE TRANSFERASE
Descriptor:MU CLASS GLUTATHIONE S-TRANSFERASE OF ISOENZYME 3-3, SULFATE ION, L-gamma-glutamyl-S-[(9S,10S)-10-hydroxy-9,10-dihydrophenanthren-9-yl]-L-cysteinylglycine
Authors:Xiao, G., Ji, X., Armstrong, R.N., Gilliland, G.L.
Deposit date:1996-01-26
Release date:1996-11-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:First-sphere and second-sphere electrostatic effects in the active site of a class mu gluthathione transferase.
Biochemistry, 35, 1996
6GSV
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FIRST-SPHERE AND SECOND-SPHERE ELECTROSTATIC EFFECTS IN THE ACTIVE SITE OF A CLASS MU GLUTATHIONE TRANSFERASE
Descriptor:MU CLASS GLUTATHIONE S-TRANSFERASE OF ISOENZYME 3-3, SULFATE ION, L-gamma-glutamyl-S-[(9S,10S)-10-hydroxy-9,10-dihydrophenanthren-9-yl]-L-cysteinylglycine
Authors:Xiao, G., Ji, X., Armstrong, R.N., Gilliland, G.L.
Deposit date:1996-01-26
Release date:1996-11-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:First-sphere and second-sphere electrostatic effects in the active site of a class mu gluthathione transferase.
Biochemistry, 35, 1996
6GSW
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FIRST-SPHERE AND SECOND-SPHERE ELECTROSTATIC EFFECTS IN THE ACTIVE SITE OF A CLASS MU GLUTATHIONE TRANSFERASE
Descriptor:MU CLASS GLUTATHIONE S-TRANSFERASE OF ISOENZYME 3-3, SULFATE ION, L-gamma-glutamyl-S-[(9S,10S)-10-hydroxy-9,10-dihydrophenanthren-9-yl]-L-cysteinylglycine
Authors:Xiao, G., Ji, X., Armstrong, R.N., Gilliland, G.L.
Deposit date:1996-01-26
Release date:1996-11-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:First-sphere and second-sphere electrostatic effects in the active site of a class mu gluthathione transferase.
Biochemistry, 35, 1996
6GSX
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FIRST-SPHERE AND SECOND-SPHERE ELECTROSTATIC EFFECTS IN THE ACTIVE SITE OF A CLASS MU GLUTATHIONE TRANSFERASE
Descriptor:MU CLASS GLUTATHIONE S-TRANSFERASE OF ISOENZYME 3-3, SULFATE ION, L-gamma-glutamyl-S-[(9S,10S)-10-hydroxy-9,10-dihydrophenanthren-9-yl]-L-cysteinylglycine
Authors:Xiao, G., Ji, X., Armstrong, R.N., Gilliland, G.L.
Deposit date:1996-01-26
Release date:1996-11-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.91 Å)
Cite:First-sphere and second-sphere electrostatic effects in the active site of a class mu gluthathione transferase.
Biochemistry, 35, 1996
6GSY
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FIRST-SPHERE AND SECOND-SPHERE ELECTROSTATIC EFFECTS IN THE ACTIVE SITE OF A CLASS MU GLUTATHIONE TRANSFERASE
Descriptor:MU CLASS GLUTATHIONE S-TRANSFERASE OF ISOENZYME 3-3, GLUTATHIONE
Authors:Xiao, G., Ji, X., Armstrong, R.N., Gilliland, G.L.
Deposit date:1996-01-26
Release date:1996-11-08
Last modified:2011-12-07
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:First-sphere and second-sphere electrostatic effects in the active site of a class mu gluthathione transferase.
Biochemistry, 35, 1996
1GSQ
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THREE-DIMENSIONAL STRUCTURE, CATALYTIC PROPERTIES AND EVOLUTION OF A SIGMA CLASS GLUTATHIONE TRANSFERASE FROM SQUID, A PROGENITOR OF THE LENS-CRYSTALLINS OF CEPHALOPODS
Descriptor:GLUTATHIONE S-TRANSFERASE, GLUTATHIONE S-(2,4 DINITROBENZENE)
Authors:Ji, X., Rosenvinge, E.C.V., Armstrong, R.N., Gilliland, G.L.
Deposit date:1995-01-09
Release date:1995-06-03
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Three-dimensional structure, catalytic properties, and evolution of a sigma class glutathione transferase from squid, a progenitor of the lens S-crystallins of cephalopods.
Biochemistry, 34, 1995
2GST
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STRUCTURE OF THE XENOBIOTIC SUBSTRATE BINDING SITE OF A GLUTATHIONE S-TRANSFERASE AS REVEALED BY X-RAY CRYSTALLOGRAPHIC ANALYSIS OF PRODUCT COMPLEXES WITH THE DIASTEREOMERS OF 9-(S-GLUTATHIONYL)-10-HYDROXY-9, 10-DIHYDROPHENANTHRENE
Descriptor:GLUTATHIONE S-TRANSFERASE, SULFATE ION, L-gamma-glutamyl-S-[(9S,10S)-10-hydroxy-9,10-dihydrophenanthren-9-yl]-L-cysteinylglycine
Authors:Ji, X., Armstrong, R.N., Gilliland, G.L.
Deposit date:1993-06-07
Release date:1993-10-31
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structure and function of the xenobiotic substrate binding site of a glutathione S-transferase as revealed by X-ray crystallographic analysis of product complexes with the diastereomers of 9-(S-glutathionyl)-10-hydroxy-9,10-dihydrophenanthrene.
Biochemistry, 33, 1994
3GST
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STRUCTURE OF THE XENOBIOTIC SUBSTRATE BINDING SITE OF A GLUTATHIONE S-TRANSFERASE AS REVEALED BY X-RAY CRYSTALLOGRAPHIC ANALYSIS OF PRODUCT COMPLEXES WITH THE DIASTEREOMERS OF 9-(S-GLUTATHIONYL)-10-HYDROXY-9, 10-DIHYDROPHENANTHRENE
Descriptor:GLUTATHIONE S-TRANSFERASE, SULFATE ION, (9R,10R)-9-(S-GLUTATHIONYL)-10-HYDROXY-9,10-DIHYDROPHENANTHRENE
Authors:Ji, X., Ammon, H.L., Armstrong, R.N., Gilliland, G.L.
Deposit date:1993-06-07
Release date:1993-10-31
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structure and function of the xenobiotic substrate binding site of a glutathione S-transferase as revealed by X-ray crystallographic analysis of product complexes with the diastereomers of 9-(S-glutathionyl)-10-hydroxy-9,10-dihydrophenanthrene.
Biochemistry, 33, 1994
4GST
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REACTION COORDINATE MOTION IN AN SNAR REACTION CATALYZED BY GLUTATHIONE TRANSFERASE
Descriptor:GLUTATHIONE S-TRANSFERASE, SULFATE ION, 1-(S-GLUTATHIONYL)-2,4,6-TRINITROCYCLOHEXA-2,5-DIENE
Authors:Ji, X., Armstrong, R.N., Gilliland, G.L.
Deposit date:1993-07-20
Release date:1993-10-31
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Snapshots along the reaction coordinate of an SNAr reaction catalyzed by glutathione transferase.
Biochemistry, 32, 1993
5FWG
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TETRA-(5-FLUOROTRYPTOPHANYL)-GLUTATHIONE TRANSFERASE
Descriptor:TETRA-(5-FLUOROTRYPTOPHANYL)-GLUTATHIONE TRANSFERASE MU CLASS, (9R,10R)-9-(S-GLUTATHIONYL)-10-HYDROXY-9,10-DIHYDROPHENANTHRENE
Authors:Parsons, J.F., Xiao, G., Armstrong, R.N., Gilliland, G.L.
Deposit date:1997-11-08
Release date:1999-01-27
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (2 Å)
Cite:Enzymes harboring unnatural amino acids: mechanistic and structural analysis of the enhanced catalytic activity of a glutathione transferase containing 5-fluorotryptophan.
Biochemistry, 37, 1998
5GST
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REACTION COORDINATE MOTION IN AN SNAR REACTION CATALYZED BY GLUTATHIONE TRANSFERASE
Descriptor:GLUTATHIONE S-TRANSFERASE, SULFATE ION, GLUTATHIONE S-(2,4 DINITROBENZENE)
Authors:Ji, X., Armstrong, R.N., Gilliland, G.L.
Deposit date:1993-07-20
Release date:1993-10-31
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (2 Å)
Cite:Snapshots along the reaction coordinate of an SNAr reaction catalyzed by glutathione transferase.
Biochemistry, 32, 1993
1B4P
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CRYSTAL STRUCTURES OF CLASS MU CHIMERIC GST ISOENZYMES M1-2 AND M2-1
Descriptor:PROTEIN (GLUTATHIONE S-TRANSFERASE), SULFATE ION, L-gamma-glutamyl-S-[(9S,10S)-10-hydroxy-9,10-dihydrophenanthren-9-yl]-L-cysteinylglycine
Authors:Xiao, G., Chen, J., Armstrong, R.N., Gilliland, G.L.
Deposit date:1998-12-26
Release date:2003-07-08
Last modified:2018-04-04
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Crystal Structures of Class MU Chimeric GST Isoenzymes M1-2 and M2-1
To be Published
2GSQ
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GLUTATHIONE S-TRANSFERASE FROM SQUID DIGESTIVE GLAND COMPLEXED WITH S-(3-IODOBENZYL)GLUTATHIONE
Descriptor:GLUTATHIONE S-TRANSFERASE, SULFATE ION, S-(3-IODOBENZYL)GLUTATHIONE
Authors:Ji, X., Armstrong, R.N., Gilliland, G.L.
Deposit date:1995-04-14
Release date:1996-04-12
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Location of a potential transport binding site in a sigma class glutathione transferase by x-ray crystallography.
Proc.Natl.Acad.Sci.USA, 93, 1996
1LQK
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HIGH RESOLUTION STRUCTURE OF FOSFOMYCIN RESISTANCE PROTEIN A (FOSA)
Descriptor:probable Fosfomycin Resistance Protein, PHOSPHATE ION, POTASSIUM ION, ...
Authors:Rife, C.L., Pharris, R.E., Newcomer, M.E., Armstrong, R.N.
Deposit date:2002-05-10
Release date:2002-09-11
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (1.35 Å)
Cite:Crystal structure of a genomically encoded fosfomycin resistance protein (FosA) at 1.19 A resolution by MAD phasing off the L-III edge of Tl(+)
J.Am.Chem.Soc., 124, 2002
1LQO
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CRYSTAL STRUTCURE OF THE FOSFOMYCIN RESISTANCE PROTEIN A (FOSA) CONTAINING BOUND THALLIUM CATIONS
Descriptor:PROBABLE Fosfomycin Resistance Protein, PHOSPHATE ION, MANGANESE (II) ION, ...
Authors:Rife, C.L., Pharris, R.E., Newcomer, M.E., Armstrong, R.N.
Deposit date:2002-05-11
Release date:2002-09-11
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure of a genomically encoded fosfomycin resistance protein (FosA) at 1.19 A resolution by MAD phasing off the L-III edge of Tl(+)
J.Am.Chem.Soc., 124, 2002
1LQP
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CRYSTAL STRUCTURE OF THE FOSFOMYCIN RESISTANCE PROTEIN (FOSA) CONTAINING BOUND SUBSTRATE
Descriptor:PROBABLE FOSFOMYCIN RESISTANCE PROTEIN, POTASSIUM ION, MANGANESE (II) ION, ...
Authors:Rife, C.L., Pharris, R.E., Newcomer, M.E., Armstrong, R.N.
Deposit date:2002-05-11
Release date:2002-09-11
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.19 Å)
Cite:Crystal structure of a genomically encoded fosfomycin resistance protein (FosA) at 1.19 A resolution by MAD phasing off the L-III edge of Tl(+)
J.Am.Chem.Soc., 124, 2002
1MTC
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GLUTATHIONE TRANSFERASE MUTANT Y115F
Descriptor:Glutathione S-transferase YB1, (9R,10R)-9-(S-GLUTATHIONYL)-10-HYDROXY-9,10-DIHYDROPHENANTHRENE
Authors:Ladner, J.E., Xiao, G., Armstrong, R.N., Gilliland, G.L.
Deposit date:2002-09-20
Release date:2003-03-25
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Local protein dynamics and catalysis: detection of segmental motion associated with rate-limiting product release by a glutathione transferase
Biochemistry, 41, 2002
1N2A
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CRYSTAL STRUCTURE OF A BACTERIAL GLUTATHIONE TRANSFERASE FROM ESCHERICHIA COLI WITH GLUTATHIONE SULFONATE IN THE ACTIVE SITE
Descriptor:Glutathione S-transferase, GLUTATHIONE SULFONIC ACID
Authors:Rife, C.L., Parsons, J.F., Xiao, G., Gilliland, G.L., Armstrong, R.N.
Deposit date:2002-10-22
Release date:2003-11-04
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Conserved structural elements in glutathione transferase homologues encoded in the genome of Escherichia coli
Proteins, 53, 2003
1NKI
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CRYSTAL STRUCTURE OF THE FOSFOMYCIN RESISTANCE PROTEIN A (FOSA) CONTAINING BOUND PHOSPHONOFORMATE
Descriptor:probable fosfomycin resistance protein, POTASSIUM ION, MANGANESE (II) ION, ...
Authors:Rife, C.L., Pharris, R.E., Newcomer, M.E., Armstrong, R.N.
Deposit date:2003-01-03
Release date:2004-01-13
Last modified:2016-12-14
Method:X-RAY DIFFRACTION (0.95 Å)
Cite:Phosphonoformate: a minimal transition state analogue inhibitor of the fosfomycin resistance protein, FosA.
Biochemistry, 43, 2004
1NNR
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CRYSTAL STRUCTURE OF A PROBABLE FOSFOMYCIN RESISTANCE PROTEIN (PA1129) FROM PSEUDOMONAS AERUGINOSA WITH SULFATE PRESENT IN THE ACTIVE SITE
Descriptor:probable fosfomycin resistance protein, MANGANESE (II) ION, SULFATE ION
Authors:Rife, C.L., Pharris, R.E., Newcomer, M.E., Armstrong, R.N.
Deposit date:2003-01-14
Release date:2004-01-27
Last modified:2018-04-04
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Phosphonoformate: a minimal transition state analogue inhibitor of the fosfomycin resistance protein, FosA.
Biochemistry, 43, 2004
1NPB
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CRYSTAL STRUCTURE OF THE FOSFOMYCIN RESISTANCE PROTEIN FROM TRANSPOSON TN2921
Descriptor:fosfomycin-resistance protein, SULFATE ION, GLYCEROL
Authors:Pakhomova, S., Rife, C.L., Armstrong, R.N., Newcomer, M.E.
Deposit date:2003-01-17
Release date:2004-03-02
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structure of fosfomycin resistance protein FosA from transposon Tn2921.
Protein Sci., 13, 2004
1R4W
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CRYSTAL STRUCTURE OF MITOCHONDRIAL CLASS KAPPA GLUTATHIONE TRANSFERASE
Descriptor:Glutathione S-transferase, mitochondrial, GLUTATHIONE
Authors:Ladner, J.E., Parsons, J.F., Rife, C.L., Gilliland, G.L., Armstrong, R.N.
Deposit date:2003-10-08
Release date:2004-02-03
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Parallel Evolutionary Pathways for Glutathione Transferases: Structure and Mechanism of the Mitochondrial Class Kappa Enzyme rGSTK1-1
Biochemistry, 43, 2004
1R9C
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CRYSTAL STRUCTURE OF FOSFOMYCIN RESISTANCE PROTEIN FOSX FROM MESORHIZOBIUM LOTI
Descriptor:glutathione transferase, MANGANESE (II) ION
Authors:Fillgrove, K.L., Pakhomova, S., Newcomer, M.E., Armstrong, R.N.
Deposit date:2003-10-28
Release date:2004-02-10
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.83 Å)
Cite:Mechanistic diversity of fosfomycin resistance in pathogenic microorganisms.
J.Am.Chem.Soc., 125, 2003