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6SI9
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BU of 6si9 by Molmil
FtsZ-refold
Descriptor: 1,2-ETHANEDIOL, CALCIUM ION, Cell division protein FtsZ, ...
Authors:Fernandez-Tornero, C, Andreu, J.M, Ruiz, F.M.
Deposit date:2019-08-09
Release date:2020-02-19
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Nucleotide-induced folding of cell division protein FtsZ from Staphylococcus aureus.
Febs J., 287, 2020
4TV9
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BU of 4tv9 by Molmil
Tubulin-PM060184 complex
Descriptor: (1Z,4S,6Z)-1-[(N-{(2Z,4Z,6E,8S)-8-[(2S)-5-methoxy-6-oxo-3,6-dihydro-2H-pyran-2-yl]-6-methylnona-2,4,6-trienoyl}-3-methy l-L-valyl)amino]octa-1,6-dien-4-yl carbamate, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, ...
Authors:Prota, A.E, Bargsten, K, Diaz, J.F, Marsh, M, Cuevas, C, Liniger, M, Neuhaus, C, Andreu, J.M, Altmann, K.H, Steinmetz, M.O.
Deposit date:2014-06-26
Release date:2014-08-20
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2 Å)
Cite:A new tubulin-binding site and pharmacophore for microtubule-destabilizing anticancer drugs.
Proc.Natl.Acad.Sci.USA, 111, 2014
4TUY
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BU of 4tuy by Molmil
Tubulin-Rhizoxin complex
Descriptor: (1R,2R,3E,5R,7R,8S,10S,13E,16R)-8-hydroxy-10-[(2S,3R,4E,6E,8E)-3-methoxy-4,8-dimethyl-9-(2-methyl-1,3-oxazol-4-yl)nona-4,6,8-trien-2-yl]-2,7-dimethyl-6,11,19-trioxatricyclo[14.3.1.0~5,7~]icosa-3,13-diene-12,18-dione, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, ...
Authors:Prota, A.E, Bargsten, K, Diaz, J.F, Marsh, M, Cuevas, C, Liniger, M, Neuhaus, C, Andreu, J.M, Altmann, K.H, Steinmetz, M.O.
Deposit date:2014-06-25
Release date:2014-08-27
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:A new tubulin-binding site and pharmacophore for microtubule-destabilizing anticancer drugs.
Proc.Natl.Acad.Sci.USA, 111, 2014
4TV8
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BU of 4tv8 by Molmil
Tubulin-Maytansine complex
Descriptor: (3beta,4beta,5beta,10beta,11E,13E)-maytansine, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, ...
Authors:Prota, A.E, Bargsten, K, Diaz, J.F, Marsh, M, Cuevas, C, Liniger, M, Neuhaus, C, Andreu, J.M, Altmann, K.H, Steinmetz, M.O.
Deposit date:2014-06-26
Release date:2014-08-27
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.103 Å)
Cite:A new tubulin-binding site and pharmacophore for microtubule-destabilizing anticancer drugs.
Proc.Natl.Acad.Sci.USA, 111, 2014
3N2K
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BU of 3n2k by Molmil
TUBULIN-NSC 613862: RB3 Stathmin-like domain complex
Descriptor: GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
Authors:Barbier, P, Dorleans, A, Devred, F, Sanz, L, Allegro, D, Alfonso, C, Knossow, M, Peyrot, V, Andreu, J.M.
Deposit date:2010-05-18
Release date:2010-07-28
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (4 Å)
Cite:Stathmin and interfacial microtubule inhibitors recognize a naturally curved conformation of tubulin dimers.
J.Biol.Chem., 285, 2010
3N2G
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BU of 3n2g by Molmil
TUBULIN-NSC 613863: RB3 Stathmin-like domain complex
Descriptor: GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
Authors:Barbier, P, Dorleans, A, Devred, F, Sanz, L, Allegro, D, Alfonso, C, Knossow, M, Peyrot, V, Andreu, J.M.
Deposit date:2010-05-18
Release date:2010-07-28
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (4 Å)
Cite:Stathmin and interfacial microtubule inhibitors recognize a naturally curved conformation of tubulin dimers.
J.Biol.Chem., 285, 2010
2R75
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BU of 2r75 by Molmil
Aquifex aeolicus FtsZ with 8-morpholino-GTP
Descriptor: 8-morpholin-4-ylguanosine 5'-(tetrahydrogen triphosphate), Cell division protein ftsZ, MAGNESIUM ION
Authors:Lappchen, T, Pinas, V.A, Hartog, A.F, Koomen, G.J, Schaffner-Barbero, C, Andreu, J.M, Trambaiolo, D, Lowe, J, Juhem, A, Popov, A.V, den Blaauwen, T.
Deposit date:2007-09-07
Release date:2008-07-22
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.402 Å)
Cite:Probing FtsZ and tubulin with C8-substituted GTP analogs reveals differences in their nucleotide binding sites
Chem.Biol., 15, 2008
6YD1
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BU of 6yd1 by Molmil
SaFtsZ-DFMBA
Descriptor: 2,6-difluoro-3-methoxybenzamide, Cell division protein FtsZ, GUANOSINE-5'-DIPHOSPHATE, ...
Authors:Fernandez-Tornero, C, Ruiz, F.M, Andreu, J.M.
Deposit date:2020-03-20
Release date:2021-07-28
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Targeting the FtsZ Allosteric Binding Site with a Novel Fluorescence Polarization Screen, Cytological and Structural Approaches for Antibacterial Discovery.
J.Med.Chem., 64, 2021
6YD6
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BU of 6yd6 by Molmil
SaFtsZ-UCM152 (comp.20)
Descriptor: 1,2-ETHANEDIOL, 1-methylpyrrolidin-2-one, 2,6-bis(fluoranyl)-3-[[3-(trifluoromethyl)phenyl]methoxy]benzamide, ...
Authors:Fernandez-Tornero, C, Ruiz, F.M, Andreu, J.M.
Deposit date:2020-03-20
Release date:2021-07-28
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Targeting the FtsZ Allosteric Binding Site with a Novel Fluorescence Polarization Screen, Cytological and Structural Approaches for Antibacterial Discovery.
J.Med.Chem., 64, 2021
6YD5
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BU of 6yd5 by Molmil
SaFtsZ-UCM151 (comp. 18)
Descriptor: 1,2-ETHANEDIOL, 1-methylpyrrolidin-2-one, 3-[(3-chlorophenyl)methoxy]-2,6-bis(fluoranyl)benzamide, ...
Authors:Fernandez-Tornero, C, Ruiz, F.M, Andreu, J.M.
Deposit date:2020-03-20
Release date:2021-07-28
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Targeting the FtsZ Allosteric Binding Site with a Novel Fluorescence Polarization Screen, Cytological and Structural Approaches for Antibacterial Discovery.
J.Med.Chem., 64, 2021
6RVN
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BU of 6rvn by Molmil
aFtsz-GDP-Wat
Descriptor: CALCIUM ION, Cell division protein FtsZ, GUANOSINE-5'-DIPHOSPHATE
Authors:Fernandez-Tornero, C, Andreu, J.M.
Deposit date:2019-05-31
Release date:2020-02-19
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.242 Å)
Cite:Nucleotide-induced folding of cell division protein FtsZ from Staphylococcus aureus.
Febs J., 287, 2020
6RVP
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BU of 6rvp by Molmil
SaFtsz-GDP-MetPyr
Descriptor: 1-methylpyrrolidin-2-one, CALCIUM ION, Cell division protein FtsZ, ...
Authors:Fernandez-Tornero, C, Andreu, J.M.
Deposit date:2019-05-31
Release date:2020-02-19
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.16 Å)
Cite:Nucleotide-induced folding of cell division protein FtsZ from Staphylococcus aureus.
Febs J., 287, 2020
6RVQ
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BU of 6rvq by Molmil
SaFtsz-GDP-EthGLy
Descriptor: 1,2-ETHANEDIOL, CALCIUM ION, Cell division protein FtsZ, ...
Authors:Fernandez-Tornero, C, Andreu, J.M.
Deposit date:2019-05-31
Release date:2020-02-19
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.136 Å)
Cite:Nucleotide-induced folding of cell division protein FtsZ from Staphylococcus aureus.
Febs J., 287, 2020
6RVM
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BU of 6rvm by Molmil
Cell division protein FtsZ from Staphylococcus aureus, apo form
Descriptor: CHLORIDE ION, Cell division protein FtsZ, GLYCEROL, ...
Authors:Fernandez-Tornero, C, Andreu, J.M, Canosa-Valls, A.J.
Deposit date:2019-05-31
Release date:2020-02-19
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.155 Å)
Cite:Nucleotide-induced folding of cell division protein FtsZ from Staphylococcus aureus.
Febs J., 287, 2020
7ON3
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BU of 7on3 by Molmil
SaFtsZ complexed with GDP (soak 10 mM EGTA)
Descriptor: 1,2-ETHANEDIOL, Cell division protein FtsZ, GUANOSINE-5'-DIPHOSPHATE, ...
Authors:Fernandez-Tornero, C, Ruiz, F.M, Andreu, J.M.
Deposit date:2021-05-25
Release date:2022-03-02
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.32 Å)
Cite:FtsZ filament structures in different nucleotide states reveal the mechanism of assembly dynamics.
Plos Biol., 20, 2022
7ON2
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BU of 7on2 by Molmil
SaFtsZ complexed with GDP (soaking in 10 mM CyDTA)
Descriptor: 1,2-ETHANEDIOL, Cell division protein FtsZ, GUANOSINE-5'-DIPHOSPHATE, ...
Authors:Fernandez-Tornero, C, Ruiz, F.M, Andreu, J.M.
Deposit date:2021-05-25
Release date:2022-03-02
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.69 Å)
Cite:FtsZ filament structures in different nucleotide states reveal the mechanism of assembly dynamics.
Plos Biol., 20, 2022
7ON4
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BU of 7on4 by Molmil
SaFtsZ complexed with GDP (co-crystalization with 1mM EDTA)
Descriptor: 1,2-ETHANEDIOL, Cell division protein FtsZ, GUANOSINE-5'-DIPHOSPHATE, ...
Authors:Fernandez-Tornero, C, Ruiz, F.M, Andreu, J.M.
Deposit date:2021-05-25
Release date:2022-03-02
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.79 Å)
Cite:FtsZ filament structures in different nucleotide states reveal the mechanism of assembly dynamics.
Plos Biol., 20, 2022
7OMP
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BU of 7omp by Molmil
SaFtsZ complexed with GDPPCP and Mg2+
Descriptor: 1,2-ETHANEDIOL, Cell division protein FtsZ, MAGNESIUM ION, ...
Authors:Fernandez-Tornero, C, Ruiz, F.M, Andreu, J.M.
Deposit date:2021-05-24
Release date:2022-03-02
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.52 Å)
Cite:FtsZ filament structures in different nucleotide states reveal the mechanism of assembly dynamics.
Plos Biol., 20, 2022
7OHH
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BU of 7ohh by Molmil
SaFtsZ complexed with GDP and BeF3-
Descriptor: BERYLLIUM TRIFLUORIDE ION, Cell division protein FtsZ, GUANOSINE-5'-DIPHOSPHATE, ...
Authors:Fernandez-Tornero, C, Ruiz, F.M, Andreu, J.M.
Deposit date:2021-05-11
Release date:2022-03-02
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:FtsZ filament structures in different nucleotide states reveal the mechanism of assembly dynamics.
Plos Biol., 20, 2022
7OJA
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BU of 7oja by Molmil
SaFtsZ(D210N) complexed with GDP
Descriptor: 1,2-ETHANEDIOL, Cell division protein FtsZ, GUANOSINE-5'-DIPHOSPHATE, ...
Authors:Fernandez-Tornero, C, Ruiz, F.M, Andreu, J.M.
Deposit date:2021-05-14
Release date:2022-03-02
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.22 Å)
Cite:FtsZ filament structures in different nucleotide states reveal the mechanism of assembly dynamics.
Plos Biol., 20, 2022
7OHN
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BU of 7ohn by Molmil
SaFtsZ complexed with GDP, AlF4- and Mg2+
Descriptor: Cell division protein FtsZ, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ...
Authors:Fernandez-Tornero, C, Ruiz, F.M, Andreu, J.M.
Deposit date:2021-05-11
Release date:2022-03-02
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.62 Å)
Cite:FtsZ filament structures in different nucleotide states reveal the mechanism of assembly dynamics.
Plos Biol., 20, 2022
7OJD
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BU of 7ojd by Molmil
SaFtsZ(D46A) complexed with GDP
Descriptor: 1,2-ETHANEDIOL, Cell division protein FtsZ, GUANOSINE-5'-DIPHOSPHATE, ...
Authors:Fernandez-Tornero, C, Ruiz, F.M, Andreu, J.M.
Deposit date:2021-05-14
Release date:2022-03-02
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.82 Å)
Cite:FtsZ filament structures in different nucleotide states reveal the mechanism of assembly dynamics.
Plos Biol., 20, 2022
7OJZ
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BU of 7ojz by Molmil
SaFtsZ complexed with GMPCP
Descriptor: 1,2-ETHANEDIOL, Cell division protein FtsZ, PHOSPHOMETHYLPHOSPHONIC ACID GUANOSYL ESTER, ...
Authors:Fernandez-Tornero, C, Ruiz, F.M, Andreu, J.M.
Deposit date:2021-05-17
Release date:2022-03-02
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:FtsZ filament structures in different nucleotide states reveal the mechanism of assembly dynamics.
Plos Biol., 20, 2022
7OJC
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BU of 7ojc by Molmil
SaFtsZ(Q48A) complexed with GDP
Descriptor: 1,2-ETHANEDIOL, Cell division protein FtsZ, GUANOSINE-5'-DIPHOSPHATE, ...
Authors:Fernandez-Tornero, C, Ruiz, F.M, Andreu, J.M.
Deposit date:2021-05-14
Release date:2022-03-02
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:FtsZ filament structures in different nucleotide states reveal the mechanism of assembly dynamics.
Plos Biol., 20, 2022
7OHL
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BU of 7ohl by Molmil
SaFtsZ complexed with GDP, BeF3- and Mn2+
Descriptor: BERYLLIUM TRIFLUORIDE ION, Cell division protein FtsZ, GUANOSINE-5'-DIPHOSPHATE, ...
Authors:Fernandez-Tornero, C, Ruiz, F.M, Andreu, J.M.
Deposit date:2021-05-11
Release date:2022-03-02
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:FtsZ filament structures in different nucleotide states reveal the mechanism of assembly dynamics.
Plos Biol., 20, 2022

 

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