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2PD0
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PROTEIN CGD2_2020 FROM CRYPTOSPORIDIUM PARVUM
Descriptor:Hypothetical protein, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID
Authors:Cymborowski, M., Chruszcz, M., Hills, T., Lew, J., Melone, M., Zhao, Y., Artz, J., Wernimont, A., Edwards, A., Sundstrom, M., Weigelt, J., Bochkarev, A., Arrowsmith, C., Hui, R., Minor, W., Structural Genomics Consortium (SGC)
Deposit date:2007-03-30
Release date:2007-04-17
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Protein cgd2_2020 from Cryptosporidium parvum
To be Published
3PGG
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CRYSTAL STRUCTURE OF CRYPTOSPORIDIUM PARVUM U6 SNRNA-ASSOCIATED SM-LIKE PROTEIN LSM5
Descriptor:U6 snRNA-associated Sm-like protein LSm5. SM domain
Authors:Dong, A., Gao, M., Zhao, Y., Lew, J., Wasney, G.A., Kozieradzki, I., Vedadi, M., Edwards, A., Arrowsmith, C., Weigelt, J., Sundstrom, M., Bochkarev, A., Hui, R., Artz, J., Structural Genomics Consortium (SGC)
Deposit date:2010-11-01
Release date:2011-02-02
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (2.14 Å)
Cite:Genome-Scale Protein Expression and Structural Biology of Plasmodium Falciparum and Related Apicomplexan Organisms.
Mol.Biochem.Parasitol., 151, 2007
3TB2
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1-CYS PEROXIDOXIN FROM PLASMODIUM YOELLI
Descriptor:1-Cys peroxiredoxin, SULFATE ION, GLYCEROL, ...
Authors:Qiu, W., Artz, J.D., Vedadi, M., Sharma, S., Houston, S., Lew, J., Wasney, G., Amani, M., Xu, X., Bray, J., Sundstrom, M., Arrowsmith, C., Edwards, A., Hui, R., Bochkarev, A., Structural Genomics Consortium (SGC)
Deposit date:2011-08-04
Release date:2011-10-19
Last modified:2018-01-31
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Genome-scale protein expression and structural biology of Plasmodium falciparum and related Apicomplexan organisms.
Mol.Biochem.Parasitol., 151, 2007
2F6I
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CRYSTAL STRUCTURE OF THE CLPP PROTEASE CATALYTIC DOMAIN FROM PLASMODIUM FALCIPARUM
Descriptor:ATP-dependent CLP protease, putative
Authors:Mulichak, A., Loppnau, P., Bray, J., Amani, M., Vedadi, M., Wasney, G., Finerty, P., Sundstrom, M., Weigelt, J., Edwards, A., Arrowsmith, C., Hui, R., Plotnikova, O., Structural Genomics Consortium (SGC)
Deposit date:2005-11-29
Release date:2005-12-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:The Clp chaperones and proteases of the human malaria parasite Plasmodium falciparum.
J.Mol.Biol., 404, 2010
2Q58
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CRYPTOSPORIDIUM PARVUM PUTATIVE POLYPRENYL PYROPHOSPHATE SYNTHASE (CGD4_2550) IN COMPLEX WITH ZOLEDRONATE
Descriptor:Farnesyl pyrophosphate synthase, MAGNESIUM ION, ZOLEDRONIC ACID
Authors:Chruszcz, M., Artz, J., Zheng, H., Dong, A., Dunford, J., Lew, J., Zhao, Y., Kozieradski, I., Kavanaugh, K.L., Opperman, U., Sundstrom, M., Weigelt, J., Edwards, A., Arrowsmith, C., Bochkarev, A., Hui, R., Minor, W., Structural Genomics Consortium (SGC)
Deposit date:2007-05-31
Release date:2007-06-12
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.37 Å)
Cite:Targeting a uniquely nonspecific prenyl synthase with bisphosphonates to combat cryptosporidiosis
Chem.Biol., 15, 2008
2KDB
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SOLUTION STRUCTURE OF HUMAN UBIQUITIN-LIKE DOMAIN OF HERPUD2_9_85, NORTHEAST STRUCTURAL GENOMICS CONSORTIUM (NESG) TARGET HT53A
Descriptor:Homocysteine-responsive endoplasmic reticulum-resident ubiquitin-like domain member 2 protein
Authors:Wu, B., Yee, A., Fares, C., Lemak, A., Gutmanas, A., Doherty, R., Semesi, A., Dhe-Paganon, S., Arrowsmith, C., Northeast Structural Genomics Consortium (NESG), Structural Genomics Consortium (SGC)
Deposit date:2009-01-06
Release date:2009-02-10
Last modified:2012-05-23
Method:SOLUTION NMR
Cite:Structure of human homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 2 (Herpud2 or Herp)
To be Published
1RCS
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NMR STUDY OF TRP REPRESSOR-OPERATOR DNA COMPLEX
Descriptor:DNA (5'-D(*CP*GP*TP*AP*CP*TP*AP*GP*TP*TP*AP*AP*CP*TP*AP*GP*TP*AP*CP*G)-3'), TRP REPRESSOR, TRYPTOPHAN
Authors:Zhao, D., Zheng, Z.
Deposit date:1995-05-12
Release date:1996-06-20
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:The solution structures of the trp repressor-operator DNA complex.
J.Mol.Biol., 238, 1994
2KR1
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SOLUTION NMR STRUCTURE OF ZINC BINDING N-TERMINAL DOMAIN OF UBIQUITIN-PROTEIN LIGASE E3A FROM HOMO SAPIENS. NORTHEAST STRUCTURAL GENOMICS CONSORTIUM (NESG) TARGET HR3662
Descriptor:Ubiquitin protein ligase E3A, ZINC ION
Authors:Lemak, A., Yee, A., Fares, C., Semesi, A., Xiao, R., Montelione, G., Dhe-Paganon, S., Arrowsmith, C., Northeast Structural Genomics Consortium (NESG), Structural Genomics Consortium (SGC)
Deposit date:2009-11-27
Release date:2009-12-22
Last modified:2012-05-23
Method:SOLUTION NMR
Cite:Zn-binding AZUL domain of human ubiquitin protein ligase Ube3A.
J.Biomol.Nmr, 51, 2011
2K8Y
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SOLUTION NMR STRUCTURE OF CGI121 FROM METHANOCOCCUS JANNASCHII. NORTHEAST STRUCTURAL GENOMICS CONSORTIUM TARGET MJ0187
Descriptor:Uncharacterized protein MJ0187
Authors:Rumpel, S., Fares, C., Neculai, D., Arrowsmith, C., Montelione, G.T., Sicheri, F., Northeast Structural Genomics Consortium (NESG)
Deposit date:2008-09-25
Release date:2008-11-04
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Atomic structure of the KEOPS complex: an ancient protein kinase-containing molecular machine.
Mol.Cell, 32, 2008
2L3R
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NMR STRUCTURE OF UHRF1 TANDEM TUDOR DOMAINS IN A COMPLEX WITH HISTONE H3 PEPTIDE
Descriptor:E3 ubiquitin-protein ligase UHRF1, Histone H3
Authors:Nady, N., Lemak, A., Fares, C., Gutmanas, A., Avvakumov, G., Xue, S., Arrowsmith, C., Structural Genomics Consortium (SGC)
Deposit date:2010-09-21
Release date:2011-04-13
Last modified:2011-08-24
Method:SOLUTION NMR
Cite:Recognition of Multivalent Histone States Associated with Heterochromatin by UHRF1 Protein.
J.Biol.Chem., 286, 2011
2OO1
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CRYSTAL STRUCTURE OF THE BROMO DOMAIN 2 OF HUMAN BROMODOMAIN CONTAINING PROTEIN 3 (BRD3)
Descriptor:Bromodomain-containing protein 3, SODIUM ION, 1,2-ETHANEDIOL, ...
Authors:Filippakopoulos, P., Bullock, A., Papagrigoriou, E., Keates, T., Cooper, C., Smee, C., Ugochukwu, E., Debreczeni, J., von Delft, F., Arrowsmith, C., Edwards, A., Weigelt, J., Sundstrom, M., Knapp, S., Structural Genomics Consortium (SGC)
Deposit date:2007-01-25
Release date:2007-02-13
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Histone recognition and large-scale structural analysis of the human bromodomain family.
Cell(Cambridge,Mass.), 149, 2012
2OXC
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HUMAN DEAD-BOX RNA HELICASE DDX20, DEAD DOMAIN IN COMPLEX WITH ADP
Descriptor:Probable ATP-dependent RNA helicase DDX20, ADENOSINE-5'-DIPHOSPHATE
Authors:Karlberg, T., Ogg, D., Arrowsmith, C.H., Berglund, H., Busam, R.D., Collins, R., Dahlgren, L.G., Edwards, A., Flodin, S., Flores, A., Graslund, S., Hallberg, B.M., Hammarstrom, M., Hogbom, M., Johansson, I., Kotenyova, T., Lehtio, L., Moche, M., Nordlund, P., Nyman, T., Persson, C., Sagemark, J., Stenmark, P., Sundstrom, M., Thorsell, A.G., Van Den Berg, S., Weigelt, J., Holmberg-Schiavone, L., Structural Genomics Consortium (SGC)
Deposit date:2007-02-20
Release date:2007-02-27
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Human DEAD-box RNA helicase DDX20
To be Published
3MAO
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CRYSTAL STRUCTURE OF HUMAN METHIONINE-R-SULFOXIDE REDUCTASE B1 (MSRB1)
Descriptor:Methionine-R-sulfoxide reductase B1, FE (III) ION, SODIUM ION, ...
Authors:Chaikuad, A., Shafqat, N., Yue, W.W., Savitsky, P., Krojer, T., Ugochukwu, E., Muniz, J.R.C., Pike, A.C.W., von Delft, F., Arrowsmith, C.H., Edwards, A.M., Weigelt, J., Bountra, C., Oppermann, U., Structural Genomics Consortium (SGC)
Deposit date:2010-03-24
Release date:2010-04-07
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (1.42 Å)
Cite:Crystal Structure of Human Methionine-R-Sulfoxide Reductase B1 (MsrB1)
To be Published
1WRS
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NMR STUDY OF HOLO TRP REPRESSOR
Descriptor:HOLO TRP REPRESSOR, TRYPTOPHAN
Authors:Zhao, D., Zheng, Z.
Deposit date:1995-05-12
Release date:1996-06-20
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Refined solution structures of the Escherichia coli trp holo- and aporepressor.
J.Mol.Biol., 229, 1993
1WRT
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NMR STUDY OF APO TRP REPRESSOR
Descriptor:APO TRP REPRESSOR
Authors:Zhao, D., Zheng, Z.
Deposit date:1995-05-12
Release date:1996-06-20
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Refined solution structures of the Escherichia coli trp holo- and aporepressor.
J.Mol.Biol., 229, 1993
1YLA
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UBIQUITIN-CONJUGATING ENZYME E2-25 KDA (HUNTINGTON INTERACTING PROTEIN 2)
Descriptor:Ubiquitin-conjugating enzyme E2-25 kDa
Authors:Choe, J., Avvakumov, G.V., Newman, E.M., Mackenzie, F., Kozieradzki, I., Bochkarev, A., Sundstrom, M., Arrowsmith, C., Edwards, A., Dhe-paganon, S., Structural Genomics Consortium (SGC)
Deposit date:2005-01-19
Release date:2005-02-01
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural basis of E2-25K/UBB+1 interaction leading to proteasome inhibition and neurotoxicity
J.Biol.Chem., 285, 2010
2L11
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SOLUTION NMR STRUCTURE OF THE CBX3 IN COMPLEX WITH H3K9ME3 PEPTIDE
Descriptor:Chromobox protein homolog 3, Histone H3
Authors:Kaustov, L., Lemak, A., Fares, C., Gutmanas, A., Quang, H., Loppnau, P., Min, J., Edwards, A., Arrowsmith, C., Structural Genomics Consortium (SGC)
Deposit date:2010-07-22
Release date:2010-08-04
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Recognition and specificity determinants of the human cbx chromodomains.
J.Biol.Chem., 286, 2011
2L12
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SOLUTION NMR STRUCTURE OF THE CHROMOBOX PROTEIN 7 WITH H3K9ME3
Descriptor:Chromobox homolog 7, Histone H3
Authors:Kaustov, L., Lemak, A., Gutmanas, A., Fares, C., Quang, H., Loppnau, P., Min, J., Edwards, A., Arrowsmith, C., Structural Genomics Consortium (SGC)
Deposit date:2010-07-22
Release date:2010-08-04
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Recognition and specificity determinants of the human cbx chromodomains.
J.Biol.Chem., 286, 2011
2L1B
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SOLUTION NMR STRUCTURE OF THE CHROMOBOX PROTEIN CBX7 WITH H3K27ME3
Descriptor:Chromobox protein homolog 7, Histone H3
Authors:Kaustov, L., Lemak, A., Fares, C., Gutmanas, A., Muhandiram, R., Quang, H., Loppnau, P., Min, J., Edwards, A., Arrowsmith, C., Structural Genomics Consortium (SGC)
Deposit date:2010-07-27
Release date:2010-08-25
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Recognition and specificity determinants of the human cbx chromodomains.
J.Biol.Chem., 286, 2011
2M2J
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SOLUTION NMR STRUCTURE OF THE N-TERMINAL DOMAIN OF STM1478 FROM SALMONELLA TYPHIMURIUM LT2: TARGET STR147A OF THE NORTHEAST STRUCTURAL GENOMICS CONSORTIUM (NESG), AND APC101565 OF THE MIDWEST CENTER FOR STRUCTURAL GENOMICS (MCSG).
Descriptor:Putative periplasmic protein
Authors:Houliston, S., Yee, A., Lemak, A., Garcia, M., Wu, B., Savchenko, A., Montelione, G.T., Arrowsmith, C., Northeast Structural Genomics Consortium (NESG), Midwest Center for Structural Genomics (MCSG)
Deposit date:2012-12-21
Release date:2013-05-08
Last modified:2014-07-30
Method:SOLUTION NMR
Cite:Structural and Functional Characterization of DUF1471 Domains of Salmonella Proteins SrfN, YdgH/SssB, and YahO.
Plos One, 9, 2014
2NXB
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CRYSTAL STRUCTURE OF HUMAN BROMODOMAIN CONTAINING PROTEIN 3 (BRD3)
Descriptor:Bromodomain-containing protein 3, SODIUM ION, 1,2-ETHANEDIOL
Authors:Filippakopoulos, P., Bullock, A., Cooper, C., Keates, K., Berridge, G., Pike, A., Bunkoczi, G., Edwards, A., Arrowsmith, C., Sundstrom, M., von Delft, F., Knapp, S., Structural Genomics Consortium (SGC)
Deposit date:2006-11-17
Release date:2006-12-12
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Histone recognition and large-scale structural analysis of the human bromodomain family.
Cell(Cambridge,Mass.), 149, 2012
1EJE
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CRYSTAL STRUCTURE OF AN FMN-BINDING PROTEIN
Descriptor:FMN-BINDING PROTEIN, NICKEL (II) ION, SULFATE ION, ...
Authors:Christendat, D., Saridakis, V., Bochkarev, A., Arrowsmith, C., Edwards, A.M., Northeast Structural Genomics Consortium (NESG)
Deposit date:2000-03-02
Release date:2000-10-11
Last modified:2018-01-31
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural proteomics of an archaeon.
Nat.Struct.Biol., 7, 2000
1EPZ
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CRYSTAL STRUCTURE OF DTDP-6-DEOXY-D-XYLO-4-HEXULOASE 3,5-EPIMERASE FROM METHANOBACTERIUM THERMOAUTOTROPHICUM WITH BOUND LIGAND.
Descriptor:DTDP-6-DEOXY-D-XYLO-4-HEXULOSE 3,5-EPIMERASE, THYMIDINE-5'-DIPHOSPHATE
Authors:Christendat, D., Saridakis, V., Bochkarev, A., Pai, E.F., Arrowsmith, C., Edwards, A.M.
Deposit date:2000-03-30
Release date:2000-12-13
Last modified:2018-01-31
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Crystal structure of dTDP-4-keto-6-deoxy-D-hexulose 3,5-epimerase from Methanobacterium thermoautotrophicum complexed with dTDP.
J.Biol.Chem., 275, 2000
1JE3
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SOLUTION STRUCTURE OF EC005 FROM ESCHERICHIA COLI
Descriptor:HYPOTHETICAL 8.6 KDA PROTEIN IN AMYA-FLIE INTERGENIC REGION
Authors:Yee, A., Gutierrez, P., Kozlov, G., Denisov, A., Gehring, K., Arrowsmith, C.
Deposit date:2001-06-15
Release date:2002-03-06
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:An NMR approach to structural proteomics.
Proc.Natl.Acad.Sci.USA, 99, 2002
1Y6L
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HUMAN UBIQUITIN CONJUGATING ENZYME E2E2
Descriptor:Ubiquitin-conjugating enzyme E2E2
Authors:Walker, J.R., Avvakumov, G.V., Newman, E.M., Mackenzie, F., Kozieradzki, I., Bochkarev, A., Sundstrom, M., Arrowsmith, C., Edwards, A., Dhe-Paganon, S., Structural Genomics Consortium (SGC)
Deposit date:2004-12-06
Release date:2005-01-11
Last modified:2012-11-28
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:A human ubiquitin conjugating enzyme (E2)-HECT E3 ligase structure-function screen.
Mol Cell Proteomics, 11, 2012