Author results

5VY7
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A SELF-ASSEMBLING L-FORM DNA CRYSTAL LATTICE
分子名称:DNA (5'-D(*GP*AP*GP*CP*AP*GP*AP*CP*CP*TP*GP*AP*CP*GP*GP*AP*AP*CP*TP*CP*A)-3'), DNA (5'-D(P*CP*CP*GP*TP*CP*A)-3'), DNA (5'-D(*TP*CP*TP*GP*AP*GP*TP*T)-3'), ...
著者Simmons, C.R., Yan, H.
登録日2017-05-24
公開日2017-08-09
最終更新日2017-08-23
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Tuning the Cavity Size and Chirality of Self-Assembling 3D DNA Crystals.
J. Am. Chem. Soc., 139, 2017
5XNB
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CRYSTAL STRUCTURE OF THE ICMS-ICMW-DOTL COMPLEX OF THE LEGIONELLA TYPE IVB SECRETION SYSTEM
分子名称:DotL, IcmS protein, IcmW, ...
著者Xu, J., Xu, D., Zhu, Y.
登録日2017-05-19
公開日2017-09-27
実験手法X-RAY DIFFRACTION (2.594 Å)
主引用文献Crystal Structure of The IcmS-IcmW Complex in the Legionella Type IVb Secretion System
To Be Published
5XMZ
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VERTICILLIUM EFFECTOR PEVD1
分子名称:Effector protein PevD1, CALCIUM ION, CHLORIDE ION
著者Liu, X., Zhou, R.
登録日2017-05-17
公開日2017-07-05
最終更新日2017-09-13
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献The asparagine-rich protein NRP interacts with the Verticillium effector PevD1 and regulates the subcellular localization of cryptochrome 2
J. Exp. Bot., 68, 2017
5XMF
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CRYSTAL STRUCTURE OF FELINE MHC CLASS I FOR 2,1 ANGSTROM
分子名称:MHC class I antigen alpha chain, Beta-2-microglobulin, Gag polyprotein
著者Liang, R., Sun, Y., Wang, J., Wu, Y., Zhang, N., Xia, C.
登録日2017-05-15
公開日2017-12-13
最終更新日2019-01-16
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Major Histocompatibility Complex Class I (FLA-E*01801) Molecular Structure in Domestic Cats Demonstrates Species-Specific Characteristics in Presenting Viral Antigen Peptides
J. Virol., 92, 2018
5XMM
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FLA-E*01801-167W/S
分子名称:MHC class I antigen alpha chain, Beta-2-microglobulin, Gag polyprotein
著者Liang, R., Sun, Y., Wang, J., Wu, Y., Zhang, N., Xia, C.
登録日2017-05-15
公開日2017-12-13
最終更新日2019-01-16
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Major Histocompatibility Complex Class I (FLA-E*01801) Molecular Structure in Domestic Cats Demonstrates Species-Specific Characteristics in Presenting Viral Antigen Peptides
J. Virol., 92, 2018
5VRQ
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CRYSTAL STRUCTURE OF LEGIONELLA PNEUMOPHILA EFFECTOR ANKC
分子名称:Ankyrin repeat-containing protein
著者Kozlov, G., Wong, K., Wang, W., Skubak, P., Munoz-Escobar, J., Liu, Y., Pannu, N.S., Gehring, K., Montreal-Kingston Bacterial Structural Genomics Initiative (BSGI)
登録日2017-05-11
公開日2017-11-29
最終更新日2017-12-27
実験手法X-RAY DIFFRACTION (3.205 Å)
主引用文献Ankyrin repeats as a dimerization module.
Biochem. Biophys. Res. Commun., 495, 2018
5VOX
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YEAST V-ATPASE IN COMPLEX WITH LEGIONELLA PNEUMOPHILA EFFECTOR SIDK (ROTATIONAL STATE 1)
分子名称:V-type proton ATPase catalytic subunit A,V-type proton ATPase catalytic subunit A, V-type proton ATPase subunit B, V-type proton ATPase subunit E, ...
著者Zhao, J.
登録日2017-05-03
公開日2017-06-21
最終更新日2017-09-20
実験手法ELECTRON MICROSCOPY (6.8 Å)
主引用文献Molecular basis for the binding and modulation of V-ATPase by a bacterial effector protein.
PLoS Pathog., 13, 2017
5VOY
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YEAST V-ATPASE IN COMPLEX WITH LEGIONELLA PNEUMOPHILA EFFECTOR SIDK (ROTATIONAL STATE 2)
分子名称:V-type proton ATPase catalytic subunit A,V-type proton ATPase catalytic subunit A, V-type proton ATPase subunit B, V-type proton ATPase subunit E, ...
著者Zhao, J.
登録日2017-05-03
公開日2017-06-21
最終更新日2017-09-20
実験手法ELECTRON MICROSCOPY (7.9 Å)
主引用文献Molecular basis for the binding and modulation of V-ATPase by a bacterial effector protein.
PLoS Pathog., 13, 2017
5VOZ
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YEAST V-ATPASE IN COMPLEX WITH LEGIONELLA PNEUMOPHILA EFFECTOR SIDK (ROTATIONAL STATE 3)
分子名称:V-type proton ATPase catalytic subunit A,V-type proton ATPase catalytic subunit A, V-type proton ATPase subunit B, V-type proton ATPase subunit E, ...
著者Zhao, J.
登録日2017-05-03
公開日2017-06-28
最終更新日2017-07-26
実験手法ELECTRON MICROSCOPY (7.6 Å)
主引用文献Molecular basis for the binding and modulation of V-ATPase by a bacterial effector protein.
PLoS Pathog., 13, 2017
5VNP
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X-RAY CRYSTAL STRUCTURE OF HALOTAG BOUND TO THE P1 BENZOXADIAZOLE FLUOROGENIC LIGAND
分子名称:Haloalkane dehalogenase, N-{2-[2-(hexyloxy)ethoxy]ethyl}-N~2~-methyl-N~2~-{[7-(methylamino)-2,1,3-benzoxadiazol-4-yl]sulfonyl}glycinamide, CHLORIDE ION
著者Dunham, N.P., Boal, A.K.
登録日2017-05-01
公開日2017-06-14
最終更新日2017-11-22
実験手法X-RAY DIFFRACTION (2.23 Å)
主引用文献AgHalo: A Facile Fluorogenic Sensor to Detect Drug-Induced Proteome Stress.
Angew. Chem. Int. Ed. Engl., 56, 2017
5VO1
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DLK IN COMPLEX WITH COMPOUND 10 (5-(1-ISOPROPYL-5-(3-(OXETAN-3-YL)-3-AZABICYCLO[3.1.0]HEXAN-6-YL)-1H-PYRAZOL-3-YL)-3-(TRIFLUOROMETHYL)PYRIDIN-2-AMINE)
分子名称:Mitogen-activated protein kinase kinase kinase 12, 5-{5-[(1R,5S,6r)-3-(oxetan-3-yl)-3-azabicyclo[3.1.0]hexan-6-yl]-1-(propan-2-yl)-1H-pyrazol-3-yl}-3-(trifluoromethyl)pyridin-2-amine
著者HARRIS, S.F., YIN, J.
登録日2017-05-01
公開日2017-10-04
最終更新日2017-10-25
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献Selective Inhibitors of Dual Leucine Zipper Kinase (DLK, MAP3K12) with Activity in a Model of Alzheimer's Disease.
J. Med. Chem., 60, 2017
5VO2
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DLK IN COMPLEX WITH INHIBITOR 5-(1-ISOPROPYL-5-(1-(OXETAN-3-YL)PIPERIDIN-4-YL)-1H-PYRAZOL-3-YL)-3-(TRIFLUOROMETHYL)PYRIDIN-2-AMINE (COMPOUND 7)
分子名称:Mitogen-activated protein kinase kinase kinase 12, 5-{5-[1-(oxetan-3-yl)piperidin-4-yl]-1-(propan-2-yl)-1H-pyrazol-3-yl}-3-(trifluoromethyl)pyridin-2-amine
著者HARRIS, S.F., YIN, J.
登録日2017-05-01
公開日2017-10-04
最終更新日2017-10-25
実験手法X-RAY DIFFRACTION (2.96 Å)
主引用文献Selective Inhibitors of Dual Leucine Zipper Kinase (DLK, MAP3K12) with Activity in a Model of Alzheimer's Disease.
J. Med. Chem., 60, 2017
5NS3
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CRYSTAL STRUCTURES OF CY5 CYANINE FLUOROPHORES STACKED ONTO THE END OF DOUBLE-STRANDED RNA
分子名称:50S ribosomal protein L5, double-stranded RNA
著者Liu, Y.J., Lilley, D.M.J.
登録日2017-04-25
公開日2017-12-20
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Crystal Structures of Cyanine Fluorophores Stacked onto the End of Double-Stranded RNA.
Biophys. J., 113, 2017
5NS4
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CRYSTAL STRUCTURES OF CY3 CYANINE FLUOROPHORES STACKED ONTO THE END OF DOUBLE-STRANDED RNA
分子名称:50S ribosomal protein L5, RNA (34-MER), MAGNESIUM ION, ...
著者Liu, Y.J., Lilley, D.M.J.
登録日2017-04-25
公開日2017-12-20
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Crystal Structures of Cyanine Fluorophores Stacked onto the End of Double-Stranded RNA.
Biophys. J., 113, 2017
5VKS
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CRYSTAL STRUCTURE OF P[19] ROTAVIRUS VP8* COMPLEXED WITH LNFPI
分子名称:Outer capsid protein VP4, SULFATE ION, GLYCEROL, ...
著者Xu, S., Liu, Y., Woodruff, A., Zhong, W., Jiang, X., Kennedy, M.A.
登録日2017-04-22
公開日2017-11-08
最終更新日2017-12-06
実験手法X-RAY DIFFRACTION (1.94 Å)
主引用文献Structural basis of glycan specificity of P[19] VP8*: Implications for rotavirus zoonosis and evolution.
PLoS Pathog., 13, 2017
5VKI
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CRYSTAL STRUCTURE OF P[19] ROTAVIRUS VP8* COMPLEXED WITH MUCIN CORE 2
分子名称:Outer capsid protein VP4, SULFATE ION, GLYCEROL, ...
著者Xu, S., Liu, Y., Woodruff, A., Zhong, W., Jiang, X., Kennedy, M.A.
登録日2017-04-21
公開日2017-11-08
最終更新日2017-12-06
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural basis of glycan specificity of P[19] VP8*: Implications for rotavirus zoonosis and evolution.
PLoS Pathog., 13, 2017
5NP7
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CRYOEM STRUCTURE OF HUMAN RAD51 ON SINGLE-STRANDED DNA TO 4.2A RESOLUTION.
分子名称:DNA repair protein RAD51 homolog 1, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER
著者Short, J.M., Venkitaraman, A.
登録日2017-04-13
公開日2017-05-03
最終更新日2018-10-17
実験手法ELECTRON MICROSCOPY (4.2 Å)
主引用文献High-resolution structure of the presynaptic RAD51 filament on single-stranded DNA by electron cryo-microscopy.
Nucleic Acids Res., 44, 2016
5NP8
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PGK1 IN COMPLEX WITH CRT0063465 (3-[2-(4-BROMOPHENYL)-5,7-DIMETHYL-PYRAZOLO[1,5-A]PYRIMIDIN-6-YL]PROPANOIC ACID)
分子名称:Phosphoglycerate kinase 1, 3-[2-(4-bromophenyl)-5,7-dimethyl-pyrazolo[1,5-a]pyrimidin-6-yl]propanoic acid, 1,2-ETHANEDIOL, ...
著者Turnbull, A.P., Bilsland, A.E., Liu, Y., Sumpton, D., Stevenson, K., Cairney, C.J., Roffey, J., Jenkinson, D., Keith, W.N.
登録日2017-04-13
公開日2018-05-16
最終更新日2019-08-21
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献A Novel Pyrazolopyrimidine Ligand of Human PGK1 and Stress Sensor DJ1 Modulates the Shelterin Complex and Telomere Length Regulation.
Neoplasia, 21, 2019
5XF7
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CRYSTAL STRUCTURE OF HUMAN PROTEIN DISULFIDE ISOMERASE-LIKE PROTEIN OF THE TESTIS
分子名称:Protein disulfide-isomerase-like protein of the testis
著者Li, H., Li, J., Liu, Y., Liang, H.
登録日2017-04-08
公開日2017-12-13
最終更新日2018-02-07
実験手法X-RAY DIFFRACTION (2.381 Å)
主引用文献Crystal and solution structures of human protein-disulfide isomerase-like protein of the testis (PDILT) provide insight into its chaperone activity
J. Biol. Chem., 293, 2018
5VEI
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CRYSTAL STRUCTURE OF THE SH3 DOMAIN OF HUMAN SORBIN AND SH3 DOMAIN-CONTAINING PROTEIN 2
分子名称:Sorbin and SH3 domain-containing protein 2, UNKNOWN ATOM OR ION
著者Liu, Y., Tempel, W., Huang, H., Gu, J., Liu, K., Sidhu, S.S., Bountra, C., Arrowsmith, C.H., Edwards, A.M., Min, J., Structural Genomics Consortium (SGC)
登録日2017-04-04
公開日2017-08-02
実験手法X-RAY DIFFRACTION (1.33 Å)
主引用文献Crystal structure of the SH3 domain of human sorbin and SH3 domain-containing protein 2
To be Published
5V9P
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CRYSTAL STRUCTURE OF PYRROLIDINE AMIDE INHIBITOR [(3S)-3-(4-BROMO-1H-PYRAZOL-1-YL)PYRROLIDIN-1-YL][3-(PROPAN-2-YL)-1H-PYRAZOL-5-YL]METHANONE (COMPOUND 35) IN COMPLEX WITH KDM5A
分子名称:Lysine-specific demethylase 5A, NICKEL (II) ION, ZINC ION, ...
著者Kiefer, J.R., Liang, J., Vinogradova, M.
登録日2017-03-23
公開日2017-05-10
最終更新日2017-06-14
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献From a novel HTS hit to potent, selective, and orally bioavailable KDM5 inhibitors.
Bioorg. Med. Chem. Lett., 27, 2017
5V9T
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CRYSTAL STRUCTURE OF SELECTIVE PYRROLIDINE AMIDE KDM5A INHIBITOR N-{(3R)-1-[3-(PROPAN-2-YL)-1H-PYRAZOLE-5-CARBONYL]PYRROLIDIN-3-YL}CYCLOPROPANECARBOXAMIDE (COMPOUND 48)
分子名称:Lysine-specific demethylase 5A, NICKEL (II) ION, ZINC ION, ...
著者Kiefer, J.R., Liang, J., Vinogradova, M.
登録日2017-03-23
公開日2017-05-10
最終更新日2017-06-14
実験手法X-RAY DIFFRACTION (3.05 Å)
主引用文献From a novel HTS hit to potent, selective, and orally bioavailable KDM5 inhibitors.
Bioorg. Med. Chem. Lett., 27, 2017
5V9U
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CRYSTAL STRUCTURE OF SMALL MOLECULE ARS-1620 COVALENTLY BOUND TO K-RAS G12C
分子名称:GTPase KRas, CALCIUM ION, (S)-1-{4-[6-chloro-8-fluoro-7-(2-fluoro-6-hydroxyphenyl)quinazolin-4-yl] piperazin-1-yl}propan-1-one, ...
著者Janes, M.R., Zhang, J., Li, L.-S., Hansen, R., Peters, U., Guo, X., Chen, Y., Babbar, A., Firdaus, S.J., Feng, J., Chen, J.H., Li, S., Brehmer, D., Darjania, L., Li, S., Long, Y.O., Thach, C., Liu, Y., Zarieh, A., Ely, T., Kucharski, J.M., Kessler, L.V., Wu, T., Wang, Y., Yao, Y., Deng, X., Zarrinkar, P., Dashyant, D., Lorenzi, M.V., Hu-Lowe, D., Patricelli, M.P., Ren, P., Liu, Y.
登録日2017-03-23
公開日2018-02-07
実験手法X-RAY DIFFRACTION (1.38 Å)
主引用文献Targeting KRAS Mutant Cancers with a Covalent G12C-Specific Inhibitor.
Cell, 172, 2018
5X88
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A CRYSTAL STRUCTURE OF CUTINASES FROM MALBRANCHEA CINNAMOMEA
分子名称:cutinase
著者Jiang, Z., Yang, S.Q., You, X., Huang, P., Ma, J.W.
登録日2017-03-01
公開日2018-01-31
実験手法X-RAY DIFFRACTION (1.76 Å)
主引用文献High-level expression and characterization of a novel cutinase from Malbranchea cinnamomea suitable for butyl butyrate production.
Biotechnol Biofuels, 10, 2017
5X7Z
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CRYSTAL STRUCTURE OF MYCOBACTERIUM TUBERCULOSIS MARR FAMILY PROTEIN RV2887 COMPLEX WITH P-AMINOSALICYLIC ACID
分子名称:Uncharacterized HTH-type transcriptional regulator Rv2887, 2-HYDROXY-4-AMINOBENZOIC ACID
著者Gao, Y.R., Li, D.F., Wang, D.C., Bi, L.J.
登録日2017-02-28
公開日2017-08-09
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structural analysis of the regulatory mechanism of MarR protein Rv2887 in M. tuberculosis
Sci Rep, 7, 2017