Author results

4NEQ
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THE STRUCTURE OF UDP-GLCNAC 2-EPIMERASE FROM METHANOCALDOCOCCUS JANNASCHII
Descriptor:UDP-N-acetylglucosamine 2-epimerase, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL
Authors:Chen, S.C., Yang, C.S., Huang, C.H., Chen, Y.
Deposit date:2013-10-29
Release date:2014-04-23
Last modified:2015-06-17
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Crystal structures of the archaeal UDP-GlcNAc 2-epimerase from Methanocaldococcus jannaschii reveal a conformational change induced by UDP-GlcNAc.
Proteins, 82, 2014
4NES
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CRYSTAL STRUCTURE OF METHANOCALDOCOCCUS JANNASCHII UDP-GLCNAC 2-EPIMERASE IN COMPLEX WITH UDP-GLCNAC AND UDP
Descriptor:UDP-N-acetylglucosamine 2-epimerase, URIDINE-DIPHOSPHATE-N-ACETYLGLUCOSAMINE, URIDINE-5'-DIPHOSPHATE
Authors:Chen, S.C., Yang, C.S., Huang, C.H., Chen, Y.
Deposit date:2013-10-30
Release date:2014-04-23
Last modified:2015-06-17
Method:X-RAY DIFFRACTION (1.42 Å)
Cite:Crystal structures of the archaeal UDP-GlcNAc 2-epimerase from Methanocaldococcus jannaschii reveal a conformational change induced by UDP-GlcNAc.
Proteins, 82, 2014
4Q47
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STRUCTURE OF THE DRRECQ CATALYTIC CORE IN COMPLEX WITH ADP
Descriptor:DNA helicase RecQ, ADENOSINE-5'-DIPHOSPHATE, ZINC ION
Authors:Chen, S.C., Yang, C.S., Chen, Y.
Deposit date:2014-04-14
Release date:2015-05-20
Method:X-RAY DIFFRACTION (2.899 Å)
Cite:Crystal structure of Deinococcus radiodurans RecQ helicase catalytic core domain: the interdomain flexibility.
Biomed Res Int, 2014, 2014
4Q48
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STRUCTURE OF THE RECQ CATALYTIC CORE FROM DEINOCOCCUS RADIODURANS
Descriptor:DNA helicase RecQ, ZINC ION
Authors:Chen, S.C., Yang, C.S., Chen, Y.
Deposit date:2014-04-14
Release date:2015-05-20
Method:X-RAY DIFFRACTION (2.797 Å)
Cite:Crystal structure of Deinococcus radiodurans RecQ helicase catalytic core domain: the interdomain flexibility.
Biomed Res Int, 2014, 2014
4QVG
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CRYSTAL STRUCTURE OF S-ADENOSYLMETHIONINE-DEPENDENT METHYLTRANSFERASE SIBL IN ITS APO FORM
Descriptor:SibL
Authors:Liu, J.S., Chen, S.C., Huang, C.H., Yang, C.S., Chen, Y.
Deposit date:2014-07-15
Release date:2015-05-27
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structure and mechanism of an antibiotics-synthesizing 3-hydroxykynurenine C-methyltransferase
Sci Rep, 5, 2015
4U1Q
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CRYSTAL STRUCTURE OF S-ADENOSYLMETHIONINE-DEPENDENT METHYLTRANSFERASE SIBL IN COMPLEX WITH 3HK AND SAH
Descriptor:SibL, (2S)-2-amino-4-(2-amino-3-hydroxyphenyl)-4-oxobutanoic acid, S-ADENOSYL-L-HOMOCYSTEINE
Authors:liu, J.S., Chen, S.C., Yang, C.S., Huang, C.H., Chen, Y.
Deposit date:2014-07-16
Release date:2015-08-05
Method:X-RAY DIFFRACTION (2.085 Å)
Cite:Crystal structure of S-adenosylmethionine-dependent methyltransferase SibL in complex with 3HK and SAH
To Be Published
4U88
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STRUCTURE OF THE DNA-BINDING DOMAIN OF THE RESPONSE REGULATOR SAER FROM STAPHYLOCOCCUS AUREUS
Descriptor:Transcriptional regulator SaeR
Authors:Liu, J.S., Huang, C.H., Yang, C.S., Chen, S.C., Chen, Y.
Deposit date:2014-08-01
Release date:2015-08-12
Method:X-RAY DIFFRACTION (2.355 Å)
Cite:Structure of the DNA-Binding Domain of the Response Regulator SaeR from Staphylococcus aureus
To Be Published
4X3Q
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CRYSTAL STRUCTURE OF S-ADENOSYLMETHIONINE-DEPENDENT METHYLTRANSFERASE SIBL IN COMPLEX WITH SAH
Descriptor:SibL, S-ADENOSYL-L-HOMOCYSTEINE
Authors:liu, J.S., Chen, S.C., Yang, C.S., Huang, C.H., Chen, Y.
Deposit date:2014-12-01
Release date:2015-11-25
Method:X-RAY DIFFRACTION (2.586 Å)
Cite:Crystal structure of S-adenosylmethionine-dependent methyltransferase SibL in complex with SAH
To Be Published, 2015
4ZHT
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CRYSTAL STRUCTURE OF UDP-GLCNAC 2-EPIMERASE
Descriptor:Bifunctional UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase, URIDINE-5'-DIPHOSPHATE, CYTIDINE-5'-MONOPHOSPHATE-5-N-ACETYLNEURAMINIC ACID, ...
Authors:Chen, S.C., Yang, C.S., Ko, T.P., Chen, Y.
Deposit date:2015-04-27
Release date:2016-06-01
Last modified:2016-11-09
Method:X-RAY DIFFRACTION (2.69 Å)
Cite:Mechanism and inhibition of human UDP-GlcNAc 2-epimerase, the key enzyme in sialic acid biosynthesis.
Sci Rep, 6, 2016
4ZNO
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CRYSTAL STRUCTURE OF DLN1 COMPLEXED WITH SUCROSE
Descriptor:Natterin-like protein, SUCROSE, CHLORIDE ION, ...
Authors:Jia, N., Jiang, Y.L., Cheng, W., Wang, H.W., Zhou, C.Z., Chen, Y.
Deposit date:2015-05-05
Release date:2016-01-20
Last modified:2016-03-30
Method:X-RAY DIFFRACTION (1.86 Å)
Cite:Structural basis for receptor recognition and pore formation of a zebrafish aerolysin-like protein.
Embo Rep., 17, 2016
4ZNQ
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CRYSTAL STRUCTURE OF DLN1 COMPLEXED WITH MAN(ALPHA1-2)MAN
Descriptor:Natterin-like protein, ALPHA-D-MANNOSE, CHLORIDE ION, ...
Authors:Jia, N., Jiang, Y.L., Cheng, W., Wang, H.W., Zhou, C.Z., Chen, Y.
Deposit date:2015-05-05
Release date:2016-01-20
Last modified:2016-03-30
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural basis for receptor recognition and pore formation of a zebrafish aerolysin-like protein.
Embo Rep., 17, 2016
4ZNR
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CRYSTAL STRUCTURE OF DLN1 COMPLEXED WITH MAN(ALPHA1-3)MAN
Descriptor:Natterin-like protein, ALPHA-D-MANNOSE, CHLORIDE ION, ...
Authors:Jia, N., Jiang, Y.L., Cheng, W., Wang, H.W., Zhou, C.Z., Chen, Y.
Deposit date:2015-05-05
Release date:2016-01-20
Last modified:2016-03-30
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural basis for receptor recognition and pore formation of a zebrafish aerolysin-like protein.
Embo Rep., 17, 2016
5DI0
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CRYSTAL STRUCTURE OF DLN1
Descriptor:Natterin-like protein, 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, ...
Authors:Jia, N., Jiang, Y.L., Cheng, W., Wang, H.W., Zhou, C.Z., Chen, Y.
Deposit date:2015-08-31
Release date:2016-02-03
Last modified:2016-03-30
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structural basis for receptor recognition and pore formation of a zebrafish aerolysin-like protein.
Embo Rep., 17, 2016
5XVS
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CRYSTAL STRUCTURE OF UDP-GLCNAC 2-EPIMERASE NEUC COMPLEXED WITH UDP
Descriptor:GDP/UDP-N,N'-diacetylbacillosamine 2-epimerase (Hydrolyzing), LITHIUM ION, URIDINE-5'-DIPHOSPHATE, ...
Authors:Ko, T.P., Hsieh, T.J., Chen, S.C., Wu, S.C., Guan, H.H., Yang, C.H., Chen, C.J., Chen, Y.
Deposit date:2017-06-28
Release date:2018-04-11
Last modified:2018-07-11
Method:X-RAY DIFFRACTION (2.383 Å)
Cite:The tetrameric structure of sialic acid-synthesizing UDP-GlcNAc 2-epimerase fromAcinetobacter baumannii: A comparative study with human GNE.
J. Biol. Chem., 293, 2018
5YI6
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CRISPR ASSOCIATED PROTEIN CAS6
Descriptor:CRISPR-associated endoribonuclease Cas6 1, GLYCEROL, PHOSPHATE ION
Authors:Ko, T.P., Hsieh, T.J., Chen, Y.
Deposit date:2017-10-03
Release date:2018-09-12
Method:X-RAY DIFFRACTION (1.852 Å)
Cite:Expression, Purification, Crystallization, and X-ray Structural Analysis of CRISPR-Associated Protein Cas6 from Methanocaldococcus jannaschii
Crystals, 7, 2018
6NEB
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MYC PROMOTER G-QUADRUPLEX WITH 1:6:1 LOOP LENGTH
Descriptor:DNA (27-MER)
Authors:Dickerhoff, J., Onel, B., Chen, L., Chen, Y., Yang, D.
Deposit date:2018-12-17
Release date:2019-02-13
Method:SOLUTION NMR
Cite:Solution Structure of a MYC Promoter G-Quadruplex with 1:6:1 Loop Length
Acs Omega, 4, 2019
1C76
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STAPHYLOKINASE (SAK) MONOMER
Descriptor:STAPHYLOKINASE
Authors:Rao, Z., Jiang, F., Liu, Y., Zhang, X., Chen, Y., Bartlam, M., Song, H., Ding, Y.
Deposit date:2000-02-01
Release date:2000-08-01
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Crystal Structure of Staphylokinase Dimer Offers New Clue to Reduction of Immunogenicity
To be published
1Y7H
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STRUCTURAL AND BIOCHEMICAL STUDIES IDENTIFY TOBACCO SABP2 AS A METHYLSALICYLATE ESTERASE AND FURTHER IMPLICATE IT IN PLANT INNATE IMMUNITY, NORTHEAST STRUCTURAL GENOMICS TARGET AR2241
Descriptor:salicylic acid-binding protein 2, THIOCYANATE ION
Authors:Forouhar, F., Yang, Y., Kumar, D., Chen, Y., Fridman, E., Park, S.W., Chiang, Y., Acton, T.B., Montelione, G.T., Pichersky, E., Klessig, D.F., Tong, L., Northeast Structural Genomics Consortium (NESG)
Deposit date:2004-12-08
Release date:2004-12-28
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (2.52 Å)
Cite:Structural and biochemical studies identify tobacco SABP2 as a methyl salicylate esterase and implicate it in plant innate immunity
Proc.Natl.Acad.Sci.Usa, 102, 2005
1Y7I
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STRUCTURAL AND BIOCHEMICAL STUDIES IDENTIFY TOBACCO SABP2 AS A METHYLSALICYLATE ESTERASE AND FURTHER IMPLICATE IT IN PLANT INNATE IMMUNITY, NORTHEAST STRUCTURAL GENOMICS TARGET AR2241
Descriptor:salicylic acid-binding protein 2, 2-HYDROXYBENZOIC ACID
Authors:Forouhar, F., Yang, Y., Kumar, D., Chen, Y., Fridman, E., Park, S.W., Chiang, Y., Acton, T.B., Montelione, G.T., Pichersky, E., Klessig, D.F., Tong, L., Northeast Structural Genomics Consortium (NESG)
Deposit date:2004-12-08
Release date:2004-12-21
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural and biochemical studies identify tobacco SABP2 as a methyl salicylate esterase and implicate it in plant innate immunity
Proc.Natl.Acad.Sci.USA, 102, 2005
3C5V
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PP2A-SPECIFIC METHYLESTERASE APO FORM (PME)
Descriptor:Protein phosphatase methylesterase 1
Authors:Xing, Y., Li, Z., Chen, Y., Stock, J., Jeffrey, P.D., Shi, Y.
Deposit date:2008-02-01
Release date:2008-04-15
Last modified:2017-07-26
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural mechanism of demethylation and inactivation of protein phosphatase 2A.
Cell(Cambridge,Mass.), 133, 2008
3C5W
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COMPLEX BETWEEN PP2A-SPECIFIC METHYLESTERASE PME-1 AND PP2A CORE ENZYME
Descriptor:PP2A A subunit, PP2A C subunit, PP2A-specific methylesterase PME-1
Authors:Xing, Y., Li, Z., Chen, Y., Stock, J., Jeffrey, P.D., Shi, Y.
Deposit date:2008-02-01
Release date:2008-04-15
Last modified:2017-07-26
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural mechanism of demethylation and inactivation of protein phosphatase 2A.
Cell(Cambridge,Mass.), 133, 2008
3DW8
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STRUCTURE OF A PROTEIN PHOSPHATASE 2A HOLOENZYME WITH B55 SUBUNIT
Descriptor:Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform, Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform, Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform, ...
Authors:Xu, Y., Chen, Y., Zhang, P., Jeffrey, P.D., Shi, Y.
Deposit date:2008-07-21
Release date:2008-10-07
Last modified:2013-10-16
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Structure of a protein phosphatase 2A holoenzyme: insights into B55-mediated Tau dephosphorylation.
Mol.Cell, 31, 2008
3FDF
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CRYSTAL STRUCTURE OF THE SERINE PHOSPHATASE OF RNA POLYMERASE II CTD (SSU72 SUPERFAMILY) FROM DROSOPHILA MELANOGASTER. ORTHORHOMBIC CRYSTAL FORM. NORTHEAST STRUCTURAL GENOMICS CONSORTIUM TARGET FR253.
Descriptor:FR253
Authors:Kuzin, A.P., Chen, Y., Seetharaman, J., Forouhar, F., Chinag, Y., Fang, Y., Cunningham, K., Ma, L.-C., Xiao, R., Liu, J., Baran, M.C., Acton, T.B., Rost, B., Montelione, G.T., Hunt, J.F., Tong, L., Northeast Structural Genomics Consortium (NESG)
Deposit date:2008-11-25
Release date:2009-01-06
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Orthorombic crystal structure of serine phosphatase of rna polymerase ii ctd from fly drosofila melanogaster. northeast structural genomics consortium target fr253.
To be Published
3FMV
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CRYSTAL STRUCTURE OF THE SERINE PHOSPHATASE OF RNA POLYMERASE II CTD (SSU72 SUPERFAMILY) FROM DROSOPHILA MELANOGASTER. MONOCLINIC CRYSTAL FORM. NORTHEAST STRUCTURAL GENOMICS CONSORTIUM TARGET FR253.
Descriptor:Serine phosphatase of RNA polymerase II CTD
Authors:Kuzin, A.P., Chen, Y., Seetharaman, J., Forouhar, F., Chinag, Y., Fang, Y., Cunningham, K., Ma, L.-C., Xiao, R., Liu, J., Baran, M.C., Acton, T.B., Rost, B., Montelione, G.T., Hunt, J.F., Tong, L., Northeast Structural Genomics Consortium (NESG)
Deposit date:2008-12-22
Release date:2009-01-06
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (3.31 Å)
Cite:Crystal structure of the serine phosphatase of RNA polymerase II CTD (SSU72 superfamily) from Drosophila melanogaster. Monoclinic crystal form. Northeast Structural Genomics Consortium target FR253.
To be Published
3GX8
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STRUCTURAL AND BIOCHEMICAL CHARACTERIZATION OF YEAST MONOTHIOL GLUTAREDOXIN GRX5
Descriptor:Monothiol glutaredoxin-5, mitochondrial, SULFATE ION
Authors:Wang, Y., He, Y.X., Yu, J., Xiong, Y., Chen, Y., Zhou, C.Z.
Deposit date:2009-04-01
Release date:2010-04-14
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.673 Å)
Cite:Structural and biochemical characterization of yeast monothiol glutaredoxin Grx5
To be Published