8RC7
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6INS
| X-RAY ANALYSIS OF THE SINGLE CHAIN B29-A1 PEPTIDE-LINKED INSULIN MOLECULE. A COMPLETELY INACTIVE ANALOGUE | Descriptor: | INSULIN, ZINC ION | Authors: | Derewenda, U, Derewenda, Z, Dodson, E.J, Dodson, G.G, Bing, X, Markussen, J. | Deposit date: | 1992-11-25 | Release date: | 1994-01-31 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | X-ray analysis of the single chain B29-A1 peptide-linked insulin molecule. A completely inactive analogue. J.Mol.Biol., 220, 1991
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4INS
| THE STRUCTURE OF 2ZN PIG INSULIN CRYSTALS AT 1.5 ANGSTROMS RESOLUTION | Descriptor: | INSULIN (CHAIN A), INSULIN (CHAIN B), ZINC ION | Authors: | Dodson, G.G, Dodson, E.J, Hodgkin, D.C, Isaacs, N.W, Vijayan, M. | Deposit date: | 1989-07-10 | Release date: | 1990-04-15 | Last modified: | 2017-11-29 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | The structure of 2Zn pig insulin crystals at 1.5 A resolution. Philos.Trans.R.Soc.London,Ser.B, 319, 1988
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2INS
| THE STRUCTURE OF DES-PHE B1 BOVINE INSULIN | Descriptor: | DES-PHE B1 INSULIN (CHAIN A), DES-PHE B1 INSULIN (CHAIN B), ZINC ION | Authors: | Smith, G.D, Duax, W.L, Dodson, E.J, Dodson, G.G, Degraaf, R.A.G, Reynolds, C.D. | Deposit date: | 1982-05-10 | Release date: | 1982-08-05 | Last modified: | 2017-11-29 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | The Structure of Des-Phe B1 Bovine Insulin Acta Crystallogr.,Sect.B, 38, 1982
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6TAA
| STRUCTURE AND MOLECULAR MODEL REFINEMENT OF ASPERGILLUS ORYZAE (TAKA) ALPHA-AMYLASE: AN APPLICATION OF THE SIMULATED-ANNEALING METHOD | Descriptor: | ALPHA-AMYLASE, CALCIUM ION | Authors: | Swift, H.J, Brady, L, Derewenda, Z.S, Dodson, E.J, Turkenburg, J.P, Wilkinson, A.J. | Deposit date: | 1992-08-21 | Release date: | 1993-10-31 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structure and molecular model refinement of Aspergillus oryzae (TAKA) alpha-amylase: an application of the simulated-annealing method. Acta Crystallogr.,Sect.B, 47, 1991
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7ATR
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4XP7
| Crystal structure of Human tRNA dihydrouridine synthase 2 | Descriptor: | 1-DEOXY-1-(7,8-DIMETHYL-2,4-DIOXO-3,4-DIHYDRO-2H-BENZO[G]PTERIDIN-1-ID-10(5H)-YL)-5-O-PHOSPHONATO-D-RIBITOL, tRNA-dihydrouridine(20) synthase [NAD(P)+]-like | Authors: | Whelan, F, Jenkins, H.T, Griffiths, S, Byrne, R.T, Dodson, E.J, Antson, A.A. | Deposit date: | 2015-01-16 | Release date: | 2015-01-28 | Last modified: | 2015-07-15 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | From bacterial to human dihydrouridine synthase: automated structure determination. Acta Crystallogr.,Sect.D, 71, 2015
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1ZNI
| INSULIN | Descriptor: | CHLORIDE ION, INSULIN, ZINC ION | Authors: | Turkenburg, M.G.W, Whittingham, J.L, Dodson, G.G, Dodson, E.J, Xiao, B, Bentley, G.A. | Deposit date: | 1997-09-23 | Release date: | 1998-01-28 | Last modified: | 2018-07-04 | Method: | X-RAY DIFFRACTION (1.498 Å) | Cite: | Structure of insulin in 4-zinc insulin. Nature, 261, 1976
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3JSD
| Insulin's biosynthesis and activity have opposing structural requirements: a new factor in neonatal diabetes mellitus | Descriptor: | CHLORIDE ION, Insulin A chain, Insulin B chain, ... | Authors: | Weiss, M.A, Wan, Z.L, Dodson, E.J, Liu, M, Xu, B, Hua, Q.X, Turkenburg, M, Whittingham, J, Nakagawa, S.H, Huang, K, Hu, S.Q, Jia, W.H, Wang, S.H, Brange, J, Whittaker, J, Arvan, P, Katsoyannis, P.G, Dodson, G.G. | Deposit date: | 2009-09-10 | Release date: | 2010-09-15 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Insulin's biosynthesis and activity have opposing structural requirements: a new factor in neonatal diabetes mellitus To be Published
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1ZNJ
| INSULIN, MONOCLINIC CRYSTAL FORM | Descriptor: | CHLORIDE ION, INSULIN, PHENOL, ... | Authors: | Turkenburg, M.G.W, Whittingham, J.L, Turkenburg, J.P, Dodson, G.G, Derewenda, U, Smith, G.D, Dodson, E.J, Derewenda, Z.S, Xiao, B. | Deposit date: | 1997-09-23 | Release date: | 1998-01-28 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structure Determination and Refinement of Two Crystal Forms of Native Insulins To be Published
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6T9M
| Crystal structure of the Chitinase Domain of the Spore Coat Protein CotE from Clostridium difficile | Descriptor: | DI(HYDROXYETHYL)ETHER, PENTAETHYLENE GLYCOL, Peptide in active site, ... | Authors: | Whittingham, J.L, Dodson, E.J, Wilkinson, A.J. | Deposit date: | 2019-10-28 | Release date: | 2020-07-22 | Method: | X-RAY DIFFRACTION (1.3 Å) | Cite: | Crystal structures of the GH18 domain of the bifunctional peroxiredoxin-chitinase CotE from Clostridium difficile. Acta Crystallogr.,Sect.F, 76, 2020
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6TSB
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3TGL
| STRUCTURE AND MOLECULAR MODEL REFINEMENT OF RHIZOMUCOR MIEHEI TRIACYLGLYCERIDE LIPASE: A CASE STUDY OF THE USE OF SIMULATED ANNEALING IN PARTIAL MODEL REFINEMENT | Descriptor: | TRIACYL-GLYCEROL ACYLHYDROLASE | Authors: | Brady, L, Brzozowski, A.M, Derewenda, Z.S, Dodson, E.J, Dodson, G.G, Tolley, S.P, Turkenburg, J.P, Christiansen, L, Huge-Jensen, B, Norskov, L, Thim, L. | Deposit date: | 1991-07-29 | Release date: | 1993-07-15 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | STRUCTURE AND MOLECULAR-MODEL REFINEMENT OF RHIZOMUCOR-MIEHEI TRIACYLGLYCERIDE LIPASE - A CASE-STUDY OF THE USE OF SIMULATED ANNEALING IN PARTIAL MODEL REFINEMENT. Acta Crystallogr.,Sect.B, 48, 1992
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3ROV
| Insulin's biosynthesis and activity have opposing structural requirements: a new factor in neonatal diabetes mellitus | Descriptor: | CHLORIDE ION, Insulin, PHENOL, ... | Authors: | Weiss, M.A, Wan, Z.L, Dodson, E.J, Liu, M, Xu, B, Hua, Q.X, Turkenburg, M, Whittingham, J, Nakagawa, S.H, Huang, K, Hu, S.Q, Jia, W.H, Wang, S.H, Brange, J, Whittaker, J, Arvan, P, Katsoyannis, P.G, Dodson, G.G. | Deposit date: | 2011-04-26 | Release date: | 2012-05-02 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Insulin's biosynthesis and activity have opposing structural requirements: a new factor in neonatal diabetes mellitus To be Published
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7SP2
| Structure of PLS A-domain (residues 391-656; 513-518 deletion mutant) from Staphylococcus aureus | Descriptor: | CALCIUM ION, Plasmin Sensitive Protein Pls | Authors: | Clark, L, Whelan, F, Atkin, K.E, Brentnall, A.S, Dodson, E.J, Turkenburg, J.P, Potts, J.R. | Deposit date: | 2021-11-02 | Release date: | 2022-11-09 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.75 Å) | Cite: | Structure of PLS A-domain (residues 391-65) from Staphylococcus aureus Not Published
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5OAH
| THE PERIPLASMIC BINDING PROTEIN CEUE OF CAMPYLOBACTER JEJUNI BINDS THE IRON(III) COMPLEX OF Azotochelin | Descriptor: | Azotochelin, Enterochelin ABC transporter substrate-binding protein, FE (III) ION | Authors: | Raines, A.D.J, Blagova, E, Dodson, E.J, Wilson, K.S, Duhme-Klair, A.K. | Deposit date: | 2017-06-22 | Release date: | 2018-08-01 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Redox-switchable siderophore anchor enables reversible artificial metalloenzyme assembly Nat Catal, 2018
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5OD5
| Periplasmic binding protein CeuE complexed with a synthetic catalyst | Descriptor: | 2,5,8,11,14,17,20,23-OCTAOXAPENTACOSAN-25-OL, 4-(aminomethyl)-~{N}-(pyridin-2-ylmethyl)benzenesulfonamide, Azotochelin, ... | Authors: | Duhme-Klair, A.K, Raines, D.J, Clarke, J.E, Blagova, E.V, Dodson, E.J, Wilson, K.S. | Deposit date: | 2017-07-04 | Release date: | 2018-08-01 | Last modified: | 2018-09-26 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Redox-switchable siderophore anchor enables reversible artificial metalloenzyme assembly Nat Catal, 2018
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3MTH
| X-RAY CRYSTALLOGRAPHIC STUDIES ON HEXAMERIC INSULINS IN THE PRESENCE OF HELIX-STABILIZING AGENTS, THIOCYANATE, METHYLPARABEN AND PHENOL | Descriptor: | 4-HYDROXY-BENZOIC ACID METHYL ESTER, CHLORIDE ION, METHYLPARABEN INSULIN, ... | Authors: | Whittingham, J.L, Dodson, E.J, Moody, P.C.E, Dodson, G.G. | Deposit date: | 1995-09-13 | Release date: | 1996-01-29 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | X-ray crystallographic studies on hexameric insulins in the presence of helix-stabilizing agents, thiocyanate, methylparaben, and phenol. Biochemistry, 34, 1995
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1WAP
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2TCI
| X-RAY CRYSTALLOGRAPHIC STUDIES ON HEXAMERIC INSULINS IN THE PRESENCE OF HELIX-STABILIZING AGENTS, THIOCYANATE, METHYLPARABEN AND PHENOL | Descriptor: | THIOCYANATE INSULIN, THIOCYANATE ION, ZINC ION | Authors: | Whittingham, J.L, Dodson, E.J, Moody, P.C.E, Dodson, G.G. | Deposit date: | 1995-09-13 | Release date: | 1996-01-29 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | X-ray crystallographic studies on hexameric insulins in the presence of helix-stabilizing agents, thiocyanate, methylparaben, and phenol. Biochemistry, 34, 1995
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1QAW
| Regulatory Features of the TRP Operon and the Crystal Structure of the TRP RNA-Binding Attenuation Protein from Bacillus Stearothermophilus. | Descriptor: | TRP RNA-BINDING ATTENUATION PROTEIN, TRYPTOPHAN | Authors: | Chen, X.-P, Antson, A.A, Yang, M, Baumann, C, Dodson, E.J, Dodson, G.G, Gollnick, P. | Deposit date: | 1999-03-31 | Release date: | 1999-04-16 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Regulatory features of the trp operon and the crystal structure of the trp RNA-binding attenuation protein from Bacillus stearothermophilus. J.Mol.Biol., 289, 1999
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1C9S
| CRYSTAL STRUCTURE OF A COMPLEX OF TRP RNA-BINDING ATTENUATION PROTEIN WITH A 53-BASE SINGLE STRANDED RNA CONTAINING ELEVEN GAG TRIPLETS SEPARATED BY AU DINUCLEOTIDES | Descriptor: | SINGLE STRANDED RNA (55-MER), TRP RNA-BINDING ATTENUATION PROTEIN, TRYPTOPHAN | Authors: | Antson, A.A, Dodson, E.J, Dodson, G.G, Greaves, R.B, Chen, X.-P, Gollnick, P. | Deposit date: | 1999-08-03 | Release date: | 1999-09-15 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structure of the trp RNA-binding attenuation protein, TRAP, bound to RNA. Nature, 401, 1999
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1UZ9
| Crystallographic and solution studies of N-lithocholyl insulin: a new generation of prolonged-acting insulins. | Descriptor: | (2S)-2-AMINO-6-({(4R)-4-[(10R,13S)-10,13-DIMETHYL-3-OXOHEXADECAHYDRO-1H-CYCLOPENTA[A]PHENANTHREN-17-YL]PENTANOYL}AMINO)HEXANOIC ACID, CHLORIDE ION, INSULIN, ... | Authors: | Whittingham, J.L, Jonassen, I, Havelund, S, Roberts, S.M, Dodson, E.J, Verma, C.S, Wilkinson, A.J, Dodson, G.G. | Deposit date: | 2004-03-08 | Release date: | 2005-03-03 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Crystallographic and Solution Studies of N-Lithocholyl Insulin: A New Generation of Prolonged-Acting Human Insulins Biochemistry, 43, 2004
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1UW3
| The crystal structure of the globular domain of sheep prion protein | Descriptor: | GLUTATHIONE, PHOSPHATE ION, PRION PROTEIN | Authors: | Haire, L.F, Whyte, S.M, Vasisht, N, Gill, A.C, Verma, C, Dodson, E.J, Dodson, G.G, Bayley, P.M. | Deposit date: | 2004-01-29 | Release date: | 2004-03-25 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | The Crystal Structure of the Globular Domain of Sheep Prion Protein J.Mol.Biol., 336, 2004
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1W8P
| Structural properties of the B25Tyr-NMe-B26Phe insulin mutant. | Descriptor: | INSULIN A-CHAIN, INSULIN B-CHAIN, PHENOL, ... | Authors: | Zakowa, L, Au-Alvarez, O, Dodson, E.J, Dodson, G.G, Brzozowski, A.M. | Deposit date: | 2004-09-24 | Release date: | 2005-02-03 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.08 Å) | Cite: | Towards the Insulin-Igf-I Intermediate Structures: Functional and Structural Properties of the B25Tyr-Nme-B26Phe Insulin Mutant. Biochemistry, 43, 2004
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