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6P7S
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CRYSTAL STRUCTURE OF THE CEDAR HENIPAVIRUS ATTACHMENT G GLYCOPROTEIN GLOBULAR DOMAIN IN COMPLEX WITH THE RECEPTOR EPHRIN-B1
分子名称:Attachment glycoprotein, Ephrin-B1, N-ACETYL-D-GLUCOSAMINE, ...
著者Xu, K., Nikolov, D.B., Xu, Y.
登録日2019-06-06
公開日2019-09-25
最終更新日2019-10-23
実験手法X-RAY DIFFRACTION (3.49 Å)
主引用文献Structural and functional analyses reveal promiscuous and species specific use of ephrin receptors by Cedar virus.
Proc.Natl.Acad.Sci.USA, 116, 2019
6P7Y
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CRYSTAL STRUCTURE OF THE CEDAR HENIPAVIRUS ATTACHMENT G GLYCOPROTEIN GLOBULAR DOMAIN IN COMPLEX WITH THE RECEPTOR EPHRIN-B2
分子名称:Attachment glycoprotein, Ephrin-B2, N-ACETYL-D-GLUCOSAMINE, ...
著者Xu, K., Nikolov, D.B., Xu, Y.
登録日2019-06-06
公開日2019-09-25
最終更新日2019-10-23
実験手法X-RAY DIFFRACTION (2.844 Å)
主引用文献Structural and functional analyses reveal promiscuous and species specific use of ephrin receptors by Cedar virus.
Proc.Natl.Acad.Sci.USA, 116, 2019
4PY4
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CRYSTAL STRUCTURE OF HUMAN POLY(ADP-RIBOSE) POLYMERASE 14, CATALYTIC DOMAIN IN COMPLEX WITH AN INHIBITOR XL2
分子名称:Poly [ADP-ribose] polymerase 14, 2-({4-[(1R)-1-(dimethylamino)ethyl]phenyl}amino)-6-fluoro-1,3-benzothiazole-4-carboxamide
著者Li, J., Xu, Y.
登録日2014-03-26
公開日2015-04-01
最終更新日2017-12-06
実験手法X-RAY DIFFRACTION (2.76 Å)
主引用文献Palladium-catalyzed N-arylation of 2-aminobenzothiazole-4-carboxylates/carboxamides: facile synthesis of PARP14 inhibitors
Tetrahedron, 70, 2017
2IE3
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STRUCTURE OF THE PROTEIN PHOSPHATASE 2A CORE ENZYME BOUND TO TUMOR-INDUCING TOXINS
分子名称:Protein Phosphatase 2, regulatory subunit A (PR 65), alpha isoform, ...
著者Xing, Y., Xu, Y., Chen, Y., Jeffrey, P.D., Chao, Y., Shi, Y.
登録日2006-09-17
公開日2006-11-07
最終更新日2013-02-27
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structure of Protein Phosphatase 2A Core Enzyme Bound to Tumor-Inducing Toxins
Cell(Cambridge,Mass.), 127, 2006
2IE4
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STRUCTURE OF THE PROTEIN PHOSPHATASE 2A CORE ENZYME BOUND TO OKADAIC ACID
分子名称:Protein Phosphatase 2, regulatory subunit A (PR 65), alpha isoform, ...
著者Xing, Y., Xu, Y., Chen, Y., Jeffrey, P.D., Chao, Y., Shi, Y.
登録日2006-09-17
公開日2006-11-07
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structure of Protein Phosphatase 2A Core Enzyme Bound to Tumor-Inducing Toxins
Cell(Cambridge,Mass.), 127, 2006
3N9L
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CEKDM7A FROM C.ELEGANS, COMPLEX WITH H3K4ME3 PEPTIDE AND NOG
分子名称:Putative uncharacterized protein, Histone H3 peptide, FE (II) ION, ...
著者Yang, Y., Hu, L., Wang, P., Hou, H., Chen, C.D., Xu, Y.
登録日2010-05-31
公開日2010-06-30
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.796 Å)
主引用文献Structural insights into a dual-specificity histone demethylase ceKDM7A from Caenorhabditis elegans
Cell Res., 20, 2010
3N9M
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CEKDM7A FROM C.ELEGANS, ALONE
分子名称:Putative uncharacterized protein, FE (II) ION, ZINC ION
著者Yang, Y., Hu, L., Wang, P., Hou, H., Chen, C.D., Xu, Y.
登録日2010-05-31
公開日2010-06-30
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.493 Å)
主引用文献Structural insights into a dual-specificity histone demethylase ceKDM7A from Caenorhabditis elegans
Cell Res., 20, 2010
3N9N
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CEKDM7A FROM C.ELEGANS, COMPLEX WITH H3K4ME3K9ME2 PEPTIDE AND NOG
分子名称:Putative uncharacterized protein, Histone H3 peptide, FE (II) ION, ...
著者Yang, Y., Hu, L., Wang, P., Hou, H., Chen, C.D., Xu, Y.
登録日2010-05-31
公開日2010-06-30
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.299 Å)
主引用文献Structural insights into a dual-specificity histone demethylase ceKDM7A from Caenorhabditis elegans
Cell Res., 20, 2010
3N9O
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CEKDM7A FROM C.ELEGANS, COMPLEX WITH H3K4ME3 PEPTIDE, H3K9ME2 PEPTIDE AND NOG
分子名称:Putative uncharacterized protein, Histone H3 peptide, FE (II) ION, ...
著者Yang, Y., Hu, L., Wang, P., Hou, H., Chen, C.D., Xu, Y.
登録日2010-05-31
公開日2010-06-30
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.309 Å)
主引用文献Structural insights into a dual-specificity histone demethylase ceKDM7A from Caenorhabditis elegans
Cell Res., 20, 2010
3N9P
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CEKDM7A FROM C.ELEGANS, COMPLEX WITH H3K4ME3K27ME2 PEPTIDE AND NOG
分子名称:Putative uncharacterized protein, Histone H3 peptide, FE (II) ION, ...
著者Yang, Y., Hu, L., Wang, P., Hou, H., Chen, C.D., Xu, Y.
登録日2010-05-31
公開日2010-06-30
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.388 Å)
主引用文献Structural insights into a dual-specificity histone demethylase ceKDM7A from Caenorhabditis elegans
Cell Res., 20, 2010
3N9Q
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CEKDM7A FROM C.ELEGANS, COMPLEX WITH H3K4ME3 PEPTIDE, H3K27ME2 PEPTIDE AND NOG
分子名称:Putative uncharacterized protein, Histone H3 peptide, FE (II) ION, ...
著者Yang, Y., Hu, L., Wang, P., Hou, H., Chen, C.D., Xu, Y.
登録日2010-05-31
公開日2010-06-30
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural insights into a dual-specificity histone demethylase ceKDM7A from Caenorhabditis elegans
Cell Res., 20, 2010
1TMW
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SOLUTION STRUCTURE OF HUMAN COACTOSIN LIKE PROTEIN D123N
分子名称:Coactosin-like protein
著者Dai, H., Wu, J., Xu, Y., Tang, Y., Ding, H., Shi, Y.
登録日2004-06-11
公開日2005-06-28
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献Study on Solution Structure and Its binding function to F-actin
To be Published
1U4A
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SOLUTION STRUCTURE OF HUMAN SUMO-3 C47S
分子名称:Ubiquitin-like protein SMT3A
著者Ding, H., Xu, Y., Dai, H., Tang, Y., Wu, J., Shi, Y.
登録日2004-07-23
公開日2005-03-08
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献Solution Structure of Human SUMO-3 C47S and Its Binding Surface for Ubc9
Biochemistry, 44, 2005
2D5L
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CRYSTAL STRUCTURE OF PROLYL TRIPEPTIDYL AMINOPEPTIDASE FROM PORPHYROMONAS GINGIVALIS
分子名称:dipeptidyl aminopeptidase IV, putative, SULFATE ION
著者Nakajima, Y., Ito, K., Xu, Y., Yamada, N., Onohara, Y., Yoshimoto, T.
登録日2005-11-02
公開日2006-09-19
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal Structure and Mechanism of Tripeptidyl Activity of Prolyl Tripeptidyl Aminopeptidase from Porphyromonas gingivalis
J.Mol.Biol., 362, 2006
2DCM
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THE CRYSTAL STRUCTURE OF S603A MUTATED PROLYL TRIPEPTIDYL AMINOPEPTIDASE COMPLEXED WITH SUBSTRATE
分子名称:dipeptidyl aminopeptidase IV, putative, GLYCYLALANYL-N-2-NAPHTHYL-L-PROLINEAMIDE
著者Nakajima, Y., Ito, K., Xu, Y., Yamada, N., Onohara, Y., Yoshimoto, T.
登録日2006-01-09
公開日2006-09-19
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Crystal Structure and Mechanism of Tripeptidyl Activity of Prolyl Tripeptidyl Aminopeptidase from Porphyromonas gingivalis
J.Mol.Biol., 362, 2006
3J3R
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STRUCTURAL DYNAMICS OF THE MECA-CLPC COMPLEX REVEALED BY CRYO-EM
分子名称:Adapter protein MecA 1, Negative regulator of genetic competence ClpC/MecB
著者Liu, J., Mei, Z., Li, N., Qi, Y., Xu, Y., Shi, Y., Wang, F., Lei, J., Gao, N.
登録日2013-04-18
公開日2013-05-15
最終更新日2014-10-22
実験手法ELECTRON MICROSCOPY (9.4 Å)
主引用文献Structural dynamics of the MecA-ClpC complex: a type II AAA+ protein unfolding machine
J.Biol.Chem., 288, 2013
3J3S
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STRUCTURAL DYNAMICS OF THE MECA-CLPC COMPLEX REVEALED BY CRYO-EM
分子名称:Adapter protein MecA 1, Negative regulator of genetic competence ClpC/MecB
著者Liu, J., Mei, Z., Li, N., Qi, Y., Xu, Y., Shi, Y., Wang, F., Lei, J., Gao, N.
登録日2013-04-18
公開日2013-05-15
最終更新日2015-01-21
実験手法ELECTRON MICROSCOPY (11 Å)
主引用文献Structural dynamics of the MecA-ClpC complex: a type II AAA+ protein unfolding machine.
J.Biol.Chem., 288, 2013
3J3T
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STRUCTURAL DYNAMICS OF THE MECA-CLPC COMPLEX REVEALED BY CRYO-EM
分子名称:Adapter protein MecA 1, Negative regulator of genetic competence ClpC/MecB
著者Liu, J., Mei, Z., Li, N., Qi, Y., Xu, Y., Shi, Y., Wang, F., Lei, J., Gao, N.
登録日2013-04-18
公開日2013-05-15
最終更新日2015-01-21
実験手法ELECTRON MICROSCOPY (9 Å)
主引用文献Structural dynamics of the MecA-ClpC complex: a type II AAA+ protein unfolding machine.
J.Biol.Chem., 288, 2013
3J3U
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STRUCTURAL DYNAMICS OF THE MECA-CLPC COMPLEX REVEALED BY CRYO-EM
分子名称:Adapter protein MecA 1, Negative regulator of genetic competence ClpC/MecB
著者Liu, J., Mei, Z., Li, N., Qi, Y., Xu, Y., Shi, Y., Wang, F., Lei, J., Gao, N.
登録日2013-04-18
公開日2013-05-15
最終更新日2015-01-21
実験手法ELECTRON MICROSCOPY (10 Å)
主引用文献Structural dynamics of the MecA-ClpC complex: a type II AAA+ protein unfolding machine.
J.Biol.Chem., 288, 2013
3J8G
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ELECTRON CRYO-MICROSCOPY STRUCTURE OF ENGA BOUND WITH THE 50S RIBOSOMAL SUBUNIT
分子名称:5S rRNA, 23S rRNA, 50S ribosomal protein L28, ...
著者Zhang, X., Yan, K., Zhang, Y., Li, N., Ma, C., Li, Z., Zhang, Y., Feng, B., Liu, J., Sun, Y., Xu, Y., Lei, J., Gao, N.
登録日2014-10-24
公開日2014-11-26
実験手法ELECTRON MICROSCOPY (5 Å)
主引用文献Structural insights into the function of a unique tandem GTPase EngA in bacterial ribosome assembly
Nucleic Acids Res., 2014
4RAP
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CRYSTAL STRUCTURE OF BACTERIAL IRON-CONTAINING DODECAMERIC GLYCOSYLTRANSFERASE TIBC FROM ENTEROTOXIGENIC E.COLI H10407
分子名称:Glycosyltransferase TibC, FE (III) ION, 1,2-ETHANEDIOL
著者Yao, Q., Lu, Q., Xu, Y., Shao, F.
登録日2014-09-10
公開日2014-10-29
実験手法X-RAY DIFFRACTION (2.881 Å)
主引用文献A structural mechanism for bacterial autotransporter glycosylation by a dodecameric heptosyltransferase family.
Elife, 3, 2014
5COI
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CRYSTAL STRUCTURE OF THE FIRST BROMODOMAIN OF HUMAN BRD4 IN COMPLEX WITH BENZO[CD]INDOL-2(1H)-ONE LIGAND
分子名称:Bromodomain-containing protein 4, 1-({[(1-ethyl-2-oxo-1,2-dihydrobenzo[cd]indol-6-yl)sulfonyl]amino}methyl)cyclopentanecarboxylic acid
著者Zhang, Y., Song, M., Liu, Z., Xue, X., Xu, Y.
登録日2015-07-20
公開日2016-01-13
最終更新日2016-03-09
実験手法X-RAY DIFFRACTION (1.62 Å)
主引用文献Discovery of Benzo[cd]indol-2(1H)-ones as Potent and Specific BET Bromodomain Inhibitors: Structure-Based Virtual Screening, Optimization, and Biological Evaluation
J.Med.Chem., 59, 2016
5CP5
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CRYSTAL STRUCTURE OF THE FIRST BROMODOMAIN OF HUMAN BRD4 IN COMPLEX WITH BENZO[CD]INDOL-2(1H)-ONE LIGAND
分子名称:Bromodomain-containing protein 4, 1-ethyl-N-(4-fluorophenyl)-2-oxo-1,2-dihydrobenzo[cd]indole-6-sulfonamide, 1,2-ETHANEDIOL, ...
著者Zhang, Y., Song, M., Liu, Z., Xue, X., Xu, Y.
登録日2015-07-21
公開日2016-01-13
最終更新日2016-03-09
実験手法X-RAY DIFFRACTION (1.79 Å)
主引用文献Discovery of Benzo[cd]indol-2(1H)-ones as Potent and Specific BET Bromodomain Inhibitors: Structure-Based Virtual Screening, Optimization, and Biological Evaluation
J.Med.Chem., 59, 2016
5CPE
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CRYSTAL STRUCTURE OF THE FIRST BROMODOMAIN OF HUMAN BRD4 IN COMPLEX WITH BENZO[CD]INDOL-2(1H)-ONE LIGAND
分子名称:Bromodomain-containing protein 4, 1,2-ETHANEDIOL, N-cycloheptyl-1-ethyl-2-oxo-1,2-dihydrobenzo[cd]indole-6-sulfonamide
著者Zhang, Y., Song, M., Liu, Z., Xue, X., Xu, Y.
登録日2015-07-21
公開日2016-01-13
最終更新日2016-03-09
実験手法X-RAY DIFFRACTION (1.62 Å)
主引用文献Discovery of Benzo[cd]indol-2(1H)-ones as Potent and Specific BET Bromodomain Inhibitors: Structure-Based Virtual Screening, Optimization, and Biological Evaluation
J.Med.Chem., 59, 2016
5CQT
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CRYSTAL STRUCTURE OF THE FIRST BROMODOMAIN OF HUMAN BRD4 IN COMPLEX WITH BENZO[CD]INDOL-2(1H)-ONE LIGAND
分子名称:Bromodomain-containing protein 4, N-cyclohexyl-1-ethyl-2-oxo-1,2-dihydrobenzo[cd]indole-6-sulfonamide
著者Zhang, Y., Song, M., Liu, Z., Xue, X., Xu, Y.
登録日2015-07-22
公開日2016-01-13
最終更新日2016-03-09
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Discovery of Benzo[cd]indol-2(1H)-ones as Potent and Specific BET Bromodomain Inhibitors: Structure-Based Virtual Screening, Optimization, and Biological Evaluation
J.Med.Chem., 59, 2016