Author results

1FIM
  • Download 1fim
  • View 1fim
Molmil generated image of 1fim
MACROPHAGE MIGRATION INHIBITORY FACTOR
Descriptor:MACROPHAGE MIGRATION INHIBITORY FACTOR
Authors:Suzuki, M., Sugimoto, H., Nakagawa, A., Tanaka, I.
Deposit date:1996-01-31
Release date:1996-07-11
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structure of the macrophage migration inhibitory factor from rat liver.
Nat.Struct.Biol., 3, 1996
1ODD
  • Download 1odd
  • View 1odd
Molmil generated image of 1odd
OMPR C-TERMINAL DOMAIN (OMPR-C) FROM ESCHERICHIA COLI
Descriptor:TRANSCRIPTIONAL REGULATORY PROTEIN OMPR
Authors:Kondou, H., Nakagawa, A., Tanaka, I.
Deposit date:1996-10-31
Release date:1997-05-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Escherichia coli positive regulator OmpR has a large loop structure at the putative RNA polymerase interaction site.
Nat.Struct.Biol., 4, 1997
1SQJ
  • Download 1sqj
  • View 1sqj
Molmil generated image of 1sqj
CRYSTAL STRUCTURE ANALYSIS OF OLIGOXYLOGLUCAN REDUCING-END-SPECIFIC CELLOBIOHYDROLASE (OXG-RCBH)
Descriptor:oligoxyloglucan reducing-end-specific cellobiohydrolase
Authors:Yaoi, K., Kondo, H., Noro, N., Suzuki, M., Tsuda, S., Mitsuishi, Y.
Deposit date:2004-03-19
Release date:2004-07-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Tandem Repeat of a Seven-Bladed beta-Propeller Domain in Oligoxyloglucan Reducing-End-Specific Cellobiohydrolase
Structure, 12, 2004
1V3X
  • Download 1v3x
  • View 1v3x
Molmil generated image of 1v3x
FACTOR XA IN COMPLEX WITH THE INHIBITOR 1-[6-METHYL-4,5,6,7-TETRAHYDROTHIAZOLO(5,4-C)PYRIDIN-2-YL] CARBONYL-2-CARBAMOYL-4-(6-CHLORONAPHTH-2-YLSULPHONYL)PIPERAZINE
Descriptor:Coagulation factor X, HEAVY CHAIN, LIGHT CHAIN, ...
Authors:Suzuki, M.
Deposit date:2003-11-07
Release date:2004-11-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Synthesis and conformational analysis of a non-amidine factor Xa inhibitor that incorporates 5-methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine as S4 binding element
J.Med.Chem., 47, 2004
2D1J
  • Download 2d1j
  • View 2d1j
Molmil generated image of 2d1j
FACTOR XA IN COMPLEX WITH THE INHIBITOR 2-[[4-[(5-CHLOROINDOL-2-YL)SULFONYL]PIPERAZIN-1-YL] CARBONYL]THIENO[3,2-B]PYRIDINE N-OXIDE
Descriptor:Coagulation factor X, heavy chain, light chain, ...
Authors:Suzuki, M.
Deposit date:2005-08-24
Release date:2006-08-24
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Design, synthesis, and biological activity of non-basic compounds as factor Xa inhibitors: SAR study of S1 and aryl binding sites.
Bioorg.Med.Chem., 13, 2005
2F08
  • Download 2f08
  • View 2f08
Molmil generated image of 2f08
CRYSTAL STRUCTURE OF A MAJOR HOUSE DUST MITE ALLERGEN, DERF 2
Descriptor:mite allergen Der f II, O-ACETALDEHYDYL-HEXAETHYLENE GLYCOL
Authors:Mikami, B., Tanaka, Y., Minato, N., Suzuki, M., Korematsu, S.
Deposit date:2005-11-12
Release date:2005-11-29
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structure and some properties of a major house dust mite allergen, Derf 2
Biochem.Biophys.Res.Commun., 339, 2006
3TK5
  • Download 3tk5
  • View 3tk5
Molmil generated image of 3tk5
FACTOR XA IN COMPLEX WITH D102-4380
Descriptor:Factor X heavy chain, Factor X light chain, CALCIUM ION, ...
Authors:Suzuki, M., Mochizuki, A., Nagata, T., Takano, H., Kanno, H., Kishida, M., Ohta, T.
Deposit date:2011-08-25
Release date:2012-08-29
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Zwitter ionic potent durable orally active Factor Xa inhibitor.
To be Published
5AZ0
  • Download 5az0
  • View 5az0
Molmil generated image of 5az0
CRYSTAL STRUCTURE OF ALDO-KETO REDUCTASE (AKR2E5) OF THE SILKWORM, BOMBYX MORI
Descriptor:Uncharacterized protein, CALCIUM ION, 1,2-ETHANEDIOL, ...
Authors:Yamamoto, K., Higashiura, A., Suzuki, M., Nakagawa, A.
Deposit date:2015-09-15
Release date:2016-02-10
Last modified:2016-05-18
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural characterization of an aldo-keto reductase (AKR2E5) from the silkworm Bombyx mori
Biochem.Biophys.Res.Commun., 474, 2016
6AD9
  • Download 6ad9
  • View 6ad9
Molmil generated image of 6ad9
CRYSTAL STRUCTURE OF PPARGAMMA LIGAND BINDING DOMAIN IN COMPLEX WITH DIBENZOOXEPINE DERIVATIVE COMPOUND-9
Descriptor:Peroxisome proliferator-activated receptor gamma, 12-mer peptide from Peroxisome proliferator-activated receptor gamma coactivator 1-alpha, 3-[(1E)-1-{8-[(4-methyl-2-propyl-1H-benzimidazol-1-yl)methyl]dibenzo[b,e]oxepin-11(6H)-ylidene}ethyl]-1,2,4-oxadiazol-5(4H)-one
Authors:Takahashi, Y., Suzuki, M., Yamamoto, K., Saito, J.
Deposit date:2018-07-31
Release date:2018-11-14
Last modified:2018-12-05
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Development of Dihydrodibenzooxepine Peroxisome Proliferator-Activated Receptor (PPAR) Gamma Ligands of a Novel Binding Mode as Anticancer Agents: Effective Mimicry of Chiral Structures by Olefinic E/ Z-Isomers.
J. Med. Chem., 61, 2018
5B21
  • Download 5b21
  • View 5b21
Molmil generated image of 5b21
DIMER STRUCTURE OF MURINE NECTIN-1 D1
Descriptor:murine Nectin-1 D1
Authors:Sangawa, T., Takebe, K., Suzuki, M.
Deposit date:2015-12-28
Release date:2016-12-28
Method:X-RAY DIFFRACTION (2.24 Å)
Cite:Dimer structure of murine Nectin-1 D1
To Be Published
6JIB
  • Download 6jib
  • View 6jib
Molmil generated image of 6jib
HUMAN MTHFD2 IN COMPLEX WITH DS44960156
Descriptor:Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial, 4-(5-oxo-1,5-dihydro-2H-[1]benzopyrano[3,4-c]pyridine-3(4H)-carbonyl)benzoic acid, ...
Authors:Suzuki, M., Matsui, Y., Kawai, J.
Deposit date:2019-02-20
Release date:2019-06-05
Last modified:2019-07-10
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Structure-Based Design and Synthesis of an Isozyme-Selective MTHFD2 Inhibitor with a Tricyclic Coumarin Scaffold.
Acs Med.Chem.Lett., 10, 2019
1RDC
  • Download 1rdc
  • View 1rdc
Molmil generated image of 1rdc
CRYSTAL STRUCTURES OF RIBONUCLEASE HI ACTIVE SITE MUTANTS FROM ESCHERICHIA COLI
Descriptor:RIBONUCLEASE H
Authors:Katayanagi, K., Morikawa, K.
Deposit date:1993-06-23
Release date:1993-10-31
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structures of ribonuclease HI active site mutants from Escherichia coli.
J.Biol.Chem., 268, 1993
1WU1
  • Download 1wu1
  • View 1wu1
Molmil generated image of 1wu1
FACTOR XA IN COMPLEX WITH THE INHIBITOR 4-[(5-CHLOROINDOL-2-YL)SULFONYL]-2-(2-METHYLPROPYL)-1-[[5-(PYRIDIN-4-YL) PYRIMIDIN-2-YL]CARBONYL]PIPERAZINE
Descriptor:Coagulation factor X, heavy chain, light chain, ...
Authors:Suzuki, M.
Deposit date:2004-11-29
Release date:2005-11-29
Last modified:2012-06-20
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Design, synthesis, and biological activity of non-basic compounds as factor Xa inhibitors: SAR study of S1 and aryl binding sites
Bioorg.Med.Chem., 13, 2005
2EI6
  • Download 2ei6
  • View 2ei6
Molmil generated image of 2ei6
FACTOR XA IN COMPLEX WITH THE INHIBITOR (-)-CIS-N1-[(5-CHLOROINDOL-2-YL)CARBONYL]-N2-[(5-METHYL-4,5,6,7-TETRAHYDROTHIAZOLO[5,4-C]PYRIDIN-2-YL)CARBONYL]-1,2-CYCLOHEXANEDIAMINE
Descriptor:Coagulation factor X, heavy chain, light chain, ...
Authors:Suzuki, M.
Deposit date:2007-03-12
Release date:2008-03-18
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Cycloalkanediamine derivatives as novel blood coagulation factor Xa inhibitors.
Bioorg.Med.Chem.Lett., 17, 2007
2EI7
  • Download 2ei7
  • View 2ei7
Molmil generated image of 2ei7
FACTOR XA IN COMPLEX WITH THE INHIBITOR TRANS-N1-[(5-CHLOROINDOL-2-YL)CARBONYL]-N2-[(5-METHYL-4,5,6,7-TETRAHYDROTHIAZOLO[5,4-C]PYRIDIN-2-YL)CARBONYL]-1,2-CYCLOHEXANEDIAMINE
Descriptor:Coagulation factor X, heavy chain, light chain, ...
Authors:Suzuki, M.
Deposit date:2007-03-12
Release date:2008-03-18
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Cycloalkanediamine derivatives as novel blood coagulation factor Xa inhibitors
To be Published
5AZ1
  • Download 5az1
  • View 5az1
Molmil generated image of 5az1
CRYSTAL STRUCTURE OF ALDO-KETO REDUCTASE (AKR2E5) COMPLEXED WITH NADPH
Descriptor:Uncharacterized protein, CALCIUM ION, 1,2-ETHANEDIOL, ...
Authors:Yamamoto, K., Higashiura, A., Suzuki, M., Nakagawa, A.
Deposit date:2015-09-15
Release date:2016-02-10
Last modified:2016-05-18
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural characterization of an aldo-keto reductase (AKR2E5) from the silkworm Bombyx mori
Biochem.Biophys.Res.Commun., 474, 2016
5B1D
  • Download 5b1d
  • View 5b1d
Molmil generated image of 5b1d
CRYSTAL STRUCTURE OF PROTEINASE K FROM ENGYODONTIUM ALBUM
Descriptor:Proteinase K, CALCIUM ION
Authors:Sugahara, M., Suzuki, M., Numata, K.
Deposit date:2015-12-03
Release date:2016-12-14
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structure of proteinase K from Engyodontium album
To Be Published
5B1E
  • Download 5b1e
  • View 5b1e
Molmil generated image of 5b1e
CRYSTAL STRUCTURE OF PROTEINASE K FROM ENGYODONTIUM ALBUM
Descriptor:Proteinase K, CALCIUM ION
Authors:Sugahara, M., Suzuki, M., Numata, K.
Deposit date:2015-12-03
Release date:2016-12-14
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structure of proteinase K from Engyodontium album
To Be Published
5B1F
  • Download 5b1f
  • View 5b1f
Molmil generated image of 5b1f
CRYSTAL STRUCTURE OF HEN EGG-WHITE LYSOZYME
Descriptor:Lysozyme C, SODIUM ION, CHLORIDE ION
Authors:Sugahara, M., Suzuki, M., Nango, E.
Deposit date:2015-12-03
Release date:2016-12-07
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structure of hen egg-white lysozyme
To Be Published
5B1G
  • Download 5b1g
  • View 5b1g
Molmil generated image of 5b1g
CRYSTAL STRUCTURE OF HEN EGG-WHITE LYSOZYME
Descriptor:Lysozyme C, SODIUM ION, CHLORIDE ION
Authors:Sugahara, M., Suzuki, M., Nango, E.
Deposit date:2015-12-03
Release date:2016-12-07
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structure of hen egg-white lysozyme
To Be Published
5Y5N
  • Download 5y5n
  • View 5y5n
Molmil generated image of 5y5n
CRYSTAL STRUCTURE OF HUMAN SIRTUIN 2 IN COMPLEX WITH A SELECTIVE INHIBITOR
Descriptor:NAD-dependent protein deacetylase sirtuin-2, ZINC ION, 2-[[3-(2-phenylethoxy)phenyl]amino]benzamide
Authors:Mellini, P., Itoh, Y., Tsumoto, H., Li, Y., Suzuki, M., Tokuda, N., Kakizawa, T., Miura, Y., Takeuchi, J., Lahtela-Kakkonen, M., Suzuki, T.
Deposit date:2017-08-09
Release date:2017-09-06
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Potent Mechanism-Based Sirtuin-2-Selective Inhibition by an In-Situ-Generated Occupant of the "Selectivity Pocket", Substrate Binding Site, and NAD+ Binding Pocket
CHEM SCI, 8, 2017
3AHQ
  • Download 3ahq
  • View 3ahq
Molmil generated image of 3ahq
HYPERACTIVE HUMAN ERO1
Descriptor:ERO1-like protein alpha, FLAVIN-ADENINE DINUCLEOTIDE
Authors:Inaba, K., Sitia, R., Suzuki, M.
Deposit date:2010-04-26
Release date:2010-12-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Crystal structures of human Ero1-alpha reveal the mechanisms of regulated and targeted oxidation of PDI
Embo J., 29, 2010
5B35
  • Download 5b35
  • View 5b35
Molmil generated image of 5b35
SERIAL FEMTOSECOND CRYSTALLOGRAPHY (SFX) OF GROUND STATE BACTERIORHODOPSIN CRYSTALLIZED FROM BICELLES DETERMINED USING 7-KEV X-RAY FREE ELECTRON LASER (XFEL) AT SACLA
Descriptor:Bacteriorhodopsin, RETINAL, (3R,5S,7R,8R,9S,10S,12S,13R,14S,17R)-10,13-dimethyl-17-[(2R)-pentan-2-yl]-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthrene-3,7,12-triol, ...
Authors:Mizohata, E., Nakane, T., Suzuki, M.
Deposit date:2016-02-10
Release date:2016-11-09
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Membrane protein structure determination by SAD, SIR, or SIRAS phasing in serial femtosecond crystallography using an iododetergent
Proc.Natl.Acad.Sci.USA, 113, 2016
5WS5
  • Download 5ws5
  • View 5ws5
Molmil generated image of 5ws5
NATIVE XFEL STRUCTURE OF PHOTOSYSTEM II (PREFLASH DARK DATASET)
Descriptor:Photosystem II D1 protein, Photosystem II CP47 reaction center protein, Photosystem II CP43 protein, ...
Authors:Suga, M., Shen, J.R.
Deposit date:2016-12-05
Release date:2017-03-15
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Light-induced structural changes and the site of O=O bond formation in PSII caught by XFEL.
Nature, 543, 2017
5WS6
  • Download 5ws6
  • View 5ws6
Molmil generated image of 5ws6
NATIVE XFEL STRUCTURE OF PHOTOSYSTEM II (PREFLASH TWO-FLASH DATASET
Descriptor:Photosystem II D1 protein, Photosystem II CP47 reaction center protein, Photosystem II CP43 chlorophyll protein, ...
Authors:Suga, M., Shen, J.R.
Deposit date:2016-12-05
Release date:2017-03-15
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Light-induced structural changes and the site of O=O bond formation in PSII caught by XFEL.
Nature, 543, 2017