Author results

1HVJ
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INFLUENCE OF STEREOCHEMISTRY ON ACTIVITY AND BINDING MODES FOR C2 SYMMETRY-BASED DIOL INHIBITORS OF HIV-1 PROTEASE
Descriptor:HIV-1 PROTEASE, N-{1-BENZYL-3-HYDROXY-4-[3-METHYL-2-(3-METHYL-3-PYRIDIN-2-YLMETHYL-UREIDO)-BUTYRYLAMINO]-5-PHENYL-PENTYL}-3-METHYL-2-(3-METHYL-3-PYRIDIN-2-YLMETHYL-UREIDO)-BUTYRAMIDE
Authors:Bhat, T.N., Hosur, M.V., Baldwin, E.T., Erickson, J.W.
Deposit date:1994-01-26
Release date:1994-04-30
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Influence of Stereochemistry on Activity and Binding Modes for C2 Symmetry-Based Diol Inhibitors of HIV-1 Protease
J.Am.Chem.Soc., 116, 1994
1HVK
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INFLUENCE OF STEREOCHEMISTRY ON ACTIVITY AND BINDING MODES FOR C2 SYMMETRY-BASED DIOL INHIBITORS OF HIV-1 PROTEASE
Descriptor:HIV-1 PROTEASE, N-{1-BENZYL-(2S,3S)-2,3-DIHYDROXY-4-[3-METHYL-2-(3-METHYL-3-PYRIDIN-2-YLMETHYL-UREIDO)-BUTYRYLAMINO]-5-PHENYL-PENTYL}-3-METHYL-2-(3-METHYL-3-PYRIDIN-2-YLMETHYL-UREIDO)-BUTYRAMIDE
Authors:Bhat, T.N., Hosur, M.V., Baldwin, E.T., Erickson, J.W.
Deposit date:1994-01-26
Release date:1994-04-30
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Influence of Stereochemistry on Activity and Binding Modes for C2 Symmetry-Based Diol Inhibitors of HIV-1 Protease
J.Am.Chem.Soc., 116, 1994
1HVL
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INFLUENCE OF STEREOCHEMISTRY ON ACTIVITY AND BINDING MODES FOR C2 SYMMETRY-BASED DIOL INHIBITORS OF HIV-1 PROTEASE
Descriptor:HIV-1 PROTEASE, N-{1-BENZYL-(2R,3R)-2,3-DIHYDROXY-4-[3-METHYL-2-(3-METHYL-3-PYRIDIN-2-YLMETHYL-UREIDO)-BUTYRYLAMINO]-5-PHENYL-PENTYL}-3-METHYL-2-(3-METHYL-3-PYRIDIN-2-YLMETHYL-UREIDO)-BUTYRAMIDE
Authors:Bhat, T.N., Hosur, M.V., Baldwin, E.T., Erickson, J.W.
Deposit date:1994-01-26
Release date:1994-04-30
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Influence of Stereochemistry on Activity and Binding Modes for C2 Symmetry-Based Diol Inhibitors of HIV-1 Protease
J.Am.Chem.Soc., 116, 1994
2IZA
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APOSTREPTAVIDIN PH 2.00 I4122 STRUCTURE
Descriptor:STREPTAVIDIN, FORMIC ACID
Authors:Katz, B.A.
Deposit date:1997-08-13
Release date:1998-09-16
Last modified:2017-02-08
Method:X-RAY DIFFRACTION (1.46 Å)
Cite:Binding of biotin to streptavidin stabilizes intersubunit salt bridges between Asp61 and His87 at low pH.
J.Mol.Biol., 274, 1997
2IZB
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APOSTREPTAVIDIN PH 3.12 I4122 STRUCTURE
Descriptor:STREPTAVIDIN, SULFATE ION, FORMIC ACID
Authors:Katz, B.A.
Deposit date:1997-08-13
Release date:1998-09-16
Last modified:2017-02-08
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:Binding of biotin to streptavidin stabilizes intersubunit salt bridges between Asp61 and His87 at low pH.
J.Mol.Biol., 274, 1997
2IZC
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APOSTREPTAVIDIN PH 2.0 I222 COMPLEX
Descriptor:STREPTAVIDIN, SODIUM ION, CHLORIDE ION
Authors:Katz, B.A.
Deposit date:1997-08-13
Release date:1998-09-16
Last modified:2017-02-08
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Binding of biotin to streptavidin stabilizes intersubunit salt bridges between Asp61 and His87 at low pH.
J.Mol.Biol., 274, 1997
2IZD
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APOSTREPTAVIDIN PH 3.0 I222 COMPLEX
Descriptor:STREPTAVIDIN, SULFATE ION, CHLORIDE ION, ...
Authors:Katz, B.A.
Deposit date:1997-08-13
Release date:1998-09-23
Last modified:2017-02-08
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Binding of biotin to streptavidin stabilizes intersubunit salt bridges between Asp61 and His87 at low pH.
J.Mol.Biol., 274, 1997
2IZE
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APOSTREPTAVIDIN PH 3.08 I222 COMPLEX
Descriptor:STREPTAVIDIN, SODIUM ION, CHLORIDE ION, ...
Authors:Katz, B.A.
Deposit date:1997-08-13
Release date:1998-09-16
Last modified:2017-02-08
Method:X-RAY DIFFRACTION (1.57 Å)
Cite:Binding of biotin to streptavidin stabilizes intersubunit salt bridges between Asp61 and His87 at low pH.
J.Mol.Biol., 274, 1997
2IZF
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STREPTAVIDIN-BIOTIN PH 4.0 I222 COMPLEX
Descriptor:STREPTAVIDIN, BIOTIN, SULFATE ION
Authors:Katz, B.A.
Deposit date:1997-08-13
Release date:1998-09-16
Last modified:2017-02-08
Method:X-RAY DIFFRACTION (1.58 Å)
Cite:Binding of biotin to streptavidin stabilizes intersubunit salt bridges between Asp61 and His87 at low pH.
J.Mol.Biol., 274, 1997
2IZG
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STREPTAVIDIN-BIOTIN PH 2.0 I222 COMPLEX
Descriptor:STREPTAVIDIN, BIOTIN, SULFATE ION
Authors:Katz, B.A.
Deposit date:1997-08-13
Release date:1998-09-16
Last modified:2017-02-08
Method:X-RAY DIFFRACTION (1.36 Å)
Cite:Binding of biotin to streptavidin stabilizes intersubunit salt bridges between Asp61 and His87 at low pH.
J.Mol.Biol., 274, 1997
2IZH
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STREPTAVIDIN-BIOTIN PH 10.44 I222 COMPLEX
Descriptor:STREPTAVIDIN, BIOTIN
Authors:Katz, B.A.
Deposit date:1997-08-13
Release date:1998-09-16
Last modified:2017-02-08
Method:X-RAY DIFFRACTION (1.36 Å)
Cite:Binding of biotin to streptavidin stabilizes intersubunit salt bridges between Asp61 and His87 at low pH.
J.Mol.Biol., 274, 1997
2IZI
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STREPTAVIDIN-BIOTIN PH 2.53 I4122 STRUCTURE
Descriptor:STREPTAVIDIN, BIOTIN
Authors:Katz, B.A.
Deposit date:1997-08-13
Release date:1998-09-16
Last modified:2017-02-08
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Binding of biotin to streptavidin stabilizes intersubunit salt bridges between Asp61 and His87 at low pH.
J.Mol.Biol., 274, 1997
2IZJ
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STREPTAVIDIN-BIOTIN PH 3.50 I4122 STRUCTURE
Descriptor:STREPTAVIDIN, BIOTIN
Authors:Katz, B.A.
Deposit date:1997-08-13
Release date:1998-09-16
Last modified:2017-02-08
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Binding of biotin to streptavidin stabilizes intersubunit salt bridges between Asp61 and His87 at low pH.
J.Mol.Biol., 274, 1997
2IZK
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STREPTAVIDIN-GLYCOLURIL PH 2.58 I4122 COMPLEX
Descriptor:STREPTAVIDIN, ACETATE ION, SULFATE ION, ...
Authors:Katz, B.A.
Deposit date:1997-08-13
Release date:1998-09-16
Last modified:2017-02-08
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Binding of biotin to streptavidin stabilizes intersubunit salt bridges between Asp61 and His87 at low pH.
J.Mol.Biol., 274, 1997
2IZL
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STREPTAVIDIN-2-IMINOBIOTIN PH 7.3 I222 COMPLEX
Descriptor:STREPTAVIDIN, 2-IMINOBIOTIN
Authors:Katz, B.A.
Deposit date:1997-08-13
Release date:1998-09-16
Last modified:2017-02-08
Method:X-RAY DIFFRACTION (1.48 Å)
Cite:Binding of biotin to streptavidin stabilizes intersubunit salt bridges between Asp61 and His87 at low pH.
J.Mol.Biol., 274, 1997
2M9L
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SOLUTION STRUCTURE OF PROTOXIN-1
Descriptor:Beta-theraphotoxin-Tp1a
Authors:Daly, N.
Deposit date:2013-06-13
Release date:2014-04-30
Method:SOLUTION NMR
Cite:A tarantula-venom peptide antagonizes the TRPA1 nociceptor ion channel by binding to the S1-S4 gating domain.
Curr.Biol., 24, 2014
3LPH
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CRYSTAL STRUCTURE OF THE HIV-1 REV DIMER
Descriptor:Protein Rev, SULFATE ION, BROMIDE ION, ...
Authors:Daugherty, M.D.
Deposit date:2010-02-05
Release date:2010-12-08
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural basis for cooperative RNA binding and export complex assembly by HIV Rev.
Nat.Struct.Mol.Biol., 17, 2010
3P8Z
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DENGUE METHYLTRANSFERASE BOUND TO A SAM-BASED INHIBITOR
Descriptor:Non-structural protein 5, (S)-2-amino-4-(((2S,3S,4R,5R)-5-(6-(3-chlorobenzylamino)-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methylthio)butanoic acid, S-ADENOSYL-L-HOMOCYSTEINE
Authors:Noble, C.G., Yap, L.J., Lescar, J.
Deposit date:2010-10-15
Release date:2010-12-08
Last modified:2011-09-28
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Small molecule inhibitors that selectively block dengue virus methyltransferase
J.Biol.Chem., 286, 2011
3P97
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DENGUE 3 NS5 METHYLTRANSFERASE BOUND TO THE SUBSTRATE S-ADENOSYL METHIONINE
Descriptor:Non-structural protein 5, S-ADENOSYLMETHIONINE
Authors:Noble, C.G., Yap, L.J., Lescar, J.
Deposit date:2010-10-16
Release date:2010-12-08
Last modified:2011-09-28
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Small molecule inhibitors that selectively block dengue virus methyltransferase
J.Biol.Chem., 286, 2011
3TF7
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42F3 QL9/H2-LD COMPLEX
Descriptor:H2-Ld SBM2, QL9 peptide (QLSPFPFDL), 42F3 Mut7 scFv (42F3 alpha chain, ...
Authors:Adams, J.J., Kranz, D.M., Garcia, K.C.
Deposit date:2011-08-15
Release date:2011-12-07
Last modified:2012-01-18
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:T cell receptor signaling is limited by docking geometry to peptide-major histocompatibility complex.
Immunity, 35, 2011
3TFK
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42F3-P4B10/H2-LD
Descriptor:H2-Ld SBM2, p4B10 peptide, 42F3 alpha, ...
Authors:Adams, J.J., Kranz, D.M., Garcia, K.C.
Deposit date:2011-08-15
Release date:2011-12-07
Last modified:2012-01-18
Method:X-RAY DIFFRACTION (2.753 Å)
Cite:T cell receptor signaling is limited by docking geometry to peptide-major histocompatibility complex.
Immunity, 35, 2011
3TJH
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42F3-P3A1/H2-LD COMPLEX
Descriptor:H2-Ld SBM2, p3A1, 42F3 alpha, ...
Authors:Adams, J.J., Kruse, A., Kranz, D.M., Garcia, K.C.
Deposit date:2011-08-24
Release date:2011-12-07
Last modified:2012-01-18
Method:X-RAY DIFFRACTION (2.12 Å)
Cite:T cell receptor signaling is limited by docking geometry to peptide-major histocompatibility complex.
Immunity, 35, 2011
3TPU
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42F3 P5E8/H2-LD COMPLEX
Descriptor:42F3 alpha, 42F3 beta, H2-Ld SBM2, ...
Authors:Adams, J.J., Kranz, D.M., Garcia, K.C.
Deposit date:2011-09-08
Release date:2011-12-07
Last modified:2012-01-18
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:T cell receptor signaling is limited by docking geometry to peptide-major histocompatibility complex.
Immunity, 35, 2011
3W51
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TANKYRASE IN COMPLEX WITH 2-HYDROXY-4-METHYLQUINOLINE
Descriptor:Tankyrase-2, 4-methylquinolin-2-ol, ZINC ION, ...
Authors:Jansson, A.E., Larsson, E.A., Nordlund, P.L.
Deposit date:2013-01-18
Release date:2013-07-10
Method:X-RAY DIFFRACTION (2 Å)
Cite:Fragment-based ligand design of novel potent inhibitors of tankyrases.
J.Med.Chem., 56, 2013
4IUE
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TANKYRASE IN COMPLEX WITH 7-(2-FLUOROPHENYL)-4-METHYL-1,2-DIHYDROQUINOLIN-2-ONE
Descriptor:Tankyrase-2, ZINC ION, SULFATE ION, ...
Authors:Jansson, A.E., Larsson, E.A., Nordlund, P.L.
Deposit date:2013-01-21
Release date:2013-06-26
Method:X-RAY DIFFRACTION (2.38 Å)
Cite:Fragment-based ligand design of novel potent inhibitors of tankyrases.
J.Med.Chem., 56, 2013