Author results

3ILJ
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CRYSTAL STRUCTURE OF E. COLI HPPK(D95A) IN COMPLEX WITH MGAMPCPP
Descriptor:2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase, MAGNESIUM ION, DIPHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER, ...
Authors:Blaszczyk, J., Li, Y., Yan, H., Ji, X.
Deposit date:2009-08-07
Release date:2010-08-11
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Structural and functional roles of residues D95 and D97 in E. coli HPPK
To be Published
3ILL
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CRYSTAL STRUCTURE OF E. COLI HPPK(D97A)
Descriptor:2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase, CHLORIDE ION
Authors:Blaszczyk, J., Li, Y., Yan, H., Ji, X.
Deposit date:2009-08-07
Release date:2010-08-11
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (1.73 Å)
Cite:Structural and functional roles of residues D95 and D97 in E. coli HPPK
To be Published
3ILO
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CRYSTAL STRUCTURE OF E. COLI HPPK(D97A) IN COMPLEX WITH MGAMPCPP AND 6-HYDROXYMETHYL-7,8-DIHYDROPTERIN
Descriptor:2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase, MAGNESIUM ION, DIPHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER, ...
Authors:Blaszczyk, J., Li, Y., Yan, H., Ji, X.
Deposit date:2009-08-07
Release date:2010-08-11
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (1.1 Å)
Cite:Structural and functional roles of residues D95 and D97 in E. coli HPPK
To be Published
3KUE
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CRYSTAL STRUCTURE OF E. COLI HPPK(E77A)
Descriptor:2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase, CHLORIDE ION, ACETATE ION
Authors:Blaszczyk, J., Li, Y., Yan, H., Ji, X.
Deposit date:2009-11-27
Release date:2010-11-24
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (1.538 Å)
Cite:Roles of residues E77 and H115 in E. coli HPPK
To be Published
3KUG
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CRYSTAL STRUCTURE OF E. COLI HPPK(H115A)
Descriptor:2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
Authors:Blaszczyk, J., Li, Y., Yan, H., Ji, X.
Deposit date:2009-11-27
Release date:2010-11-24
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (1.996 Å)
Cite:Roles of residues E77 and H115 in E. coli HPPK
To be Published
3KUH
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CRYSTAL STRUCTURE OF E. COLI HPPK(H115A) IN COMPLEX WITH AMPCPP AND HP
Descriptor:2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase, DIPHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER, 2-AMINO-6-HYDROXYMETHYL-7,8-DIHYDRO-3H-PTERIDIN-4-ONE, ...
Authors:Blaszczyk, J., Li, Y., Yan, H., Ji, X.
Deposit date:2009-11-27
Release date:2010-11-24
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (1.35 Å)
Cite:Roles of residues E77 and H115 in E. coli HPPK
To be Published
3O8X
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RECOGNITION OF GLYCOLIPID ANTIGEN BY INKT CELL TCR
Descriptor:Antigen-presenting glycoprotein CD1d1, Beta-2-microglobulin, Valpha14 chimera (Mouse variable domain, ...
Authors:Zajonc, D.M., Li, Y.
Deposit date:2010-08-03
Release date:2010-09-29
Last modified:2017-06-28
Method:X-RAY DIFFRACTION (2.74 Å)
Cite:The V{alpha}14 invariant natural killer T cell TCR forces microbial glycolipids and CD1d into a conserved binding mode.
J.Exp.Med., 2010
3O9W
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RECOGNITION OF A GLYCOLIPID ANTIGEN BY THE INKT CELL TCR
Descriptor:Antigen-presenting glycoprotein CD1d1, Beta-2-microglobulin, Valpha14 chimera (Mouse variable domain, ...
Authors:Zajonc, D.M., Li, Y.
Deposit date:2010-08-04
Release date:2010-09-29
Last modified:2017-06-28
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:The V{alpha}14 invariant natural killer T cell TCR forces microbial glycolipids and CD1d into a conserved binding mode.
J.Exp.Med., 2010
3QUX
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STRUCTURE OF THE MOUSE CD1D-ALPHA-C-GALCER-INKT TCR COMPLEX
Descriptor:Antigen-presenting glycoprotein CD1d1, Beta-2 microglobulin, Valpha14 (mouse variable domain, ...
Authors:Li, Y., Girardi, E., Yu, E.D., Zajonc, D.M.
Deposit date:2011-02-24
Release date:2011-06-29
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.91 Å)
Cite:Galactose-modified iNKT cell agonists stabilized by an induced fit of CD1d prevent tumour metastasis.
Embo J., 30, 2011
3QUY
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STRUCTURE OF THE MOUSE CD1D-BNNH-GSL-1'-INKT TCR COMPLEX
Descriptor:Antigen-presenting glycoprotein CD1d1, Beta-2 microglobulin, Valpha14 (mouse variable domain, ...
Authors:Li, Y., Girardi, E., Yu, E.D., Zajonc, D.M.
Deposit date:2011-02-24
Release date:2011-06-29
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Galactose-modified iNKT cell agonists stabilized by an induced fit of CD1d prevent tumour metastasis.
Embo J., 30, 2011
3QUZ
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STRUCTURE OF THE MOUSE CD1D-NU-ALPHA-GALCER-INKT TCR COMPLEX
Descriptor:Antigen-presenting glycoprotein CD1d1, Beta-2 microglobulin, Valpha14 (mouse variable domain, ...
Authors:Li, Y., Girardi, E., Yu, E.D., Zajonc, D.M.
Deposit date:2011-02-24
Release date:2011-06-29
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Galactose-modified iNKT cell agonists stabilized by an induced fit of CD1d prevent tumour metastasis.
Embo J., 30, 2011
4IS6
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CRYSTAL STRUCTURE OF HLA-DR4 BOUND TO GP100 PEPTIDE
Descriptor:HLA class II histocompatibility antigen, DR alpha chain, DRB1-4 beta chain, ...
Authors:Li, Y.
Deposit date:2013-01-16
Release date:2013-10-23
Last modified:2013-11-20
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structure-Based Design of Altered MHC Class II-Restricted Peptide Ligands with Heterogeneous Immunogenicity.
J.Immunol., 191, 2013
4P7I
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CRYSTAL STRUCTURE OF THE MERLIN FERM/DCAF1 COMPLEX
Descriptor:Merlin, Protein VPRBP, GLYCEROL
Authors:Wei, Z., Li, Y., Zhang, M.
Deposit date:2014-03-27
Release date:2014-04-09
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural basis of the binding of Merlin FERM domain to the E3 ubiquitin ligase substrate adaptor DCAF1.
J.Biol.Chem., 289, 2014
4R9V
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CRYSTAL STRUCTURE OF SIALYLTRANSFERASE FROM PHOTOBACTERIUM DAMSELAE, RESIDUES 113-497 CORRESPONDING TO THE GT-B DOMAIN
Descriptor:Sialyltransferase 0160, CALCIUM ION
Authors:Li, Y., Huynh, N., Chen, X., Fisher, A.J.
Deposit date:2014-09-08
Release date:2014-12-03
Last modified:2015-01-14
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structures of sialyltransferase from Photobacterium damselae.
Febs Lett., 588, 2014
4YZE
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CRYSTAL STRUCTURE OF E.COLI NEMR REDUCED FORM
Descriptor:HTH-type transcriptional repressor NemR
Authors:Li, Y., Gray, M.J., Jakob, U., Xu, Z.
Deposit date:2015-03-24
Release date:2016-02-03
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Does the Transcription Factor NemR Use a Regulatory Sulfenamide Bond to Sense Bleach?
Antioxid.Redox Signal., 23, 2015
4ZVV
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LACTATE DEHYDROGENASE A IN COMPLEX WITH A TRISUBSTITUTED PIPERIDINE-2,4-DIONE INHIBITOR GNE-140
Descriptor:L-lactate dehydrogenase A chain, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, SULFATE ION, ...
Authors:Li, Y., Chen, Z., Eigenbrot, C.
Deposit date:2015-05-18
Release date:2016-05-18
Last modified:2016-09-28
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Metabolic plasticity underpins innate and acquired resistance to LDHA inhibition.
Nat.Chem.Biol., 12, 2016
5V4B
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CRYSTAL STRUCTURE OF THE SKP1-FBXW7-DISC1 COMPLEX
Descriptor:S-phase kinase-associated protein 1,S-phase kinase-associated protein 1, F-box/WD repeat-containing protein 7, DISC1 peptide, ...
Authors:Li, Y., Baillie, G.S., Hao, B.
Deposit date:2017-03-08
Release date:2017-09-20
Last modified:2018-05-16
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:FBXW7 regulates DISC1 stability via the ubiquitin-proteosome system.
Mol. Psychiatry, 23, 2018
5W2J
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CRYSTAL STRUCTURE OF DIMERIC FORM OF MOUSE GLUTAMINASE C
Descriptor:Glutaminase kidney isoform, mitochondrial, unidentified peptide, ...
Authors:Cerione, R.A., Li, Y.
Deposit date:2017-06-06
Release date:2018-10-17
Last modified:2019-02-27
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Mechanistic Basis of Glutaminase Activation: A KEY ENZYME THAT PROMOTES GLUTAMINE METABOLISM IN CANCER CELLS.
J. Biol. Chem., 291, 2016
6MHU
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NUCLEOTIDE-FREE CRYO-EM STRUCTURE OF E.COLI LPTB2FG TRANSPORTER
Descriptor:Lipopolysaccharide export system permease protein LptF, Lipopolysaccharide export system permease protein LptG, Lipopolysaccharide export system ATP-binding protein LptB, ...
Authors:Orlando, B.J., Li, Y., Liao, M.
Deposit date:2018-09-18
Release date:2019-04-03
Last modified:2019-04-10
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Structural basis of lipopolysaccharide extraction by the LptB2FGC complex.
Nature, 567, 2019
6MHZ
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VANADATE TRAPPED CRYO-EM STRUCTURE OF E.COLI LPTB2FG TRANSPORTER
Descriptor:Lipopolysaccharide export system ATP-binding protein LptB, Lipopolysaccharide export system permease protein LptF, Lipopolysaccharide export system permease protein LptG, ...
Authors:Orlando, B.J., Li, Y., Liao, M.
Deposit date:2018-09-18
Release date:2019-04-03
Last modified:2019-04-10
Method:ELECTRON MICROSCOPY (4.1 Å)
Cite:Structural basis of lipopolysaccharide extraction by the LptB2FGC complex.
Nature, 567, 2019
6MI7
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NUCLEOTIDE-FREE CRYO-EM STRUCTURE OF E.COLI LPTB2FGC
Descriptor:Lipopolysaccharide export system permease protein LptF, Lipopolysaccharide export system permease protein LptG, Lipopolysaccharide export system ATP-binding protein LptB, ...
Authors:Orlando, B.J., Li, Y., Liao, M.
Deposit date:2018-09-19
Release date:2019-04-03
Last modified:2019-04-10
Method:ELECTRON MICROSCOPY (4.2 Å)
Cite:Structural basis of lipopolysaccharide extraction by the LptB2FGC complex.
Nature, 567, 2019
6MI8
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CRYO-EM STRUCTURE OF VANADATE-TRAPPED E.COLI LPTB2FGC
Descriptor:Lipopolysaccharide export system ATP-binding protein LptB, Lipopolysaccharide export system permease protein LptF, Lipopolysaccharide export system permease protein LptG, ...
Authors:Orlando, B.J., Li, Y., Liao, M.
Deposit date:2018-09-19
Release date:2019-04-03
Last modified:2019-04-10
Method:ELECTRON MICROSCOPY (4.3 Å)
Cite:Structural basis of lipopolysaccharide extraction by the LptB2FGC complex.
Nature, 567, 2019
2AXH
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CRYSTAL STRUCTURES OF T CELL RECEPTOR BETA CHAINS RELATED TO RHEUMATOID ARTHRITIS
Descriptor:T cell receptor beta chain
Authors:Li, H., Van Vranken, S., Zhao, Y., Li, Z., Guo, Y., Eisele, L., Li, Y.
Deposit date:2005-09-05
Release date:2005-09-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Crystal structures of T cell receptor (beta) chains related to rheumatoid arthritis.
Protein Sci., 14, 2005
2AXJ
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CRYSTAL STRUCTURES OF T CELL RECEPTOR BETA CHAINS RELATED TO RHEUMATOID ARTHRITIS
Descriptor:SF4 T cell receptor beta chain
Authors:Li, H., Van Vranken, S., Zhao, Y., Li, Z., Guo, Y., Eisele, L., Li, Y.
Deposit date:2005-09-05
Release date:2005-09-20
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Crystal structures of T cell receptor (beta) chains related to rheumatoid arthritis.
Protein Sci., 14, 2005
4H52
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WILD-TYPE INFLUENZA N2 NEURAMINIDASE COVALENT COMPLEX WITH 3-FLUORO-NEU5AC
Descriptor:Neuraminidase, CALCIUM ION, N-ACETYL-D-GLUCOSAMINE, ...
Authors:Vavricka, C.J., Liu, Y., Kiyota, H., Sriwilaijaroen, N., Qi, J., Tanaka, K., Wu, Y., Li, Q., Li, Y., Yan, J., Suzuki, Y., Gao, G.F.
Deposit date:2012-09-18
Release date:2013-02-20
Last modified:2013-07-31
Method:X-RAY DIFFRACTION (1.803 Å)
Cite:Influenza neuraminidase operates via a nucleophilic mechanism and can be targeted by covalent inhibitors
Nat Commun, 4, 2013