Author results

3D1B
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TETRAGONAL CRYSTAL STRUCTURE OF TAS3 C-TERMINAL ALPHA MOTIF
Descriptor:RNA-induced transcriptional silencing complex protein tas3
Authors:Li, H., Patel, D.J.
Deposit date:2008-05-05
Release date:2009-04-21
Last modified:2013-06-19
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:An alpha motif at Tas3 C terminus mediates RITS cis spreading and promotes heterochromatic gene silencing.
Mol.Cell, 34, 2009
3D1D
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HEXAGONAL CRYSTAL STRUCTURE OF TAS3 C-TERMINAL ALPHA MOTIF
Descriptor:RNA-induced transcriptional silencing complex protein tas3
Authors:Li, H., Patel, D.J.
Deposit date:2008-05-05
Release date:2009-04-21
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:An alpha motif at Tas3 C terminus mediates RITS cis spreading and promotes heterochromatic gene silencing.
Mol.Cell, 34, 2009
3E9C
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STRUCTURE OF A TRYPTIC CORE FRAGMENT OF TIGAR FROM DANIO RERIO
Descriptor:Zgc:56074, POTASSIUM ION
Authors:Li, H., Jogl, G.
Deposit date:2008-08-21
Release date:2008-12-16
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (2 Å)
Cite:TIGAR (TP53 induced glycolysis and apoptosis regulator) is a fructose-2,6- and fructose-1,6-bisphosphatase
To be Published
3E9D
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STRUCTURE OF FULL-LENGTH TIGAR FROM DANIO RERIO
Descriptor:Zgc:56074, PHOSPHATE ION, POTASSIUM ION
Authors:Li, H., Jogl, G.
Deposit date:2008-08-21
Release date:2008-12-16
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (2 Å)
Cite:TIGAR (TP53 induced glycolysis and apoptosis regulator) is a fructose-2,6- and fructose-1,6-bisphosphatase
To be Published
3E9E
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STRUCTURE OF FULL-LENGTH H11A MUTANT FORM OF TIGAR FROM DANIO RERIO
Descriptor:Zgc:56074, PHOSPHATE ION
Authors:Li, H., Jogl, G.
Deposit date:2008-08-21
Release date:2008-12-16
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:TIGAR (TP53 induced glycolysis and apoptosis regulator) is a fructose-2,6- and fructose-1,6-bisphosphatase
To be Published
3FD2
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CRYSTAL STRUCTURE OF MMSOI/DNA COMPLEX WITH CALCIUM
Descriptor:Site-specific DNA endonuclease I-MsoI, 5'-D(*GP*CP*AP*GP*AP*AP*CP*GP*TP*CP*GP*TP*GP*AP*GP*AP*CP*AP*GP*TP*TP*CP*CP*G)-3', 5'-D(*CP*GP*GP*AP*AP*CP*TP*GP*TP*CP*TP*CP*AP*CP*GP*AP*CP*GP*TP*TP*CP*TP*GP*C)-3', ...
Authors:Li, H., Monnat, R.J.
Deposit date:2008-11-24
Release date:2009-06-30
Last modified:2017-06-28
Method:X-RAY DIFFRACTION (2.69 Å)
Cite:Generation of single-chain LAGLIDADG homing endonucleases from native homodimeric precursor proteins.
Nucleic Acids Res., 37, 2009
3NO9
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CRYSTAL STRUCTURE OF APO FUMARATE HYDRATASE FROM MYCOBACTERIUM TUBERCULOSIS
Descriptor:Fumarate hydratase class II
Authors:Li, H., Swanson, S., Yu, M., Hung, L.-W., Sacchettini, J.C., TB Structural Genomics Consortium (TBSGC)
Deposit date:2010-06-25
Release date:2010-07-14
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.48 Å)
Cite:Crystal Structure of apo fumarate hydratase from Mycobacterium tuberculosis
To be Published
3S8M
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THE CRYSTAL STRUCTURE OF FABV
Descriptor:Enoyl-ACP Reductase
Authors:Li, H., Zhang, X.L., Bi, L.J., He, J., Jiang, T.
Deposit date:2011-05-29
Release date:2011-11-16
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Determination of the Crystal Structure and Active Residues of FabV, the Enoyl-ACP Reductase from Xanthomonas oryzae.
Plos One, 6, 2011
4D1N
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STRUCTURE OF HUMAN NNOS HEME DOMAIN WITH L-ARG BOUND
Descriptor:NITRIC OXIDE SYNTHASE, BRAIN, ARGININE, ...
Authors:Li, H., Poulos, T.L.
Deposit date:2014-05-02
Release date:2014-10-15
Last modified:2014-10-22
Method:X-RAY DIFFRACTION (2.03 Å)
Cite:Structures of Human Constitutive Nitric Oxide Synthases
Acta Crystallogr.,Sect.D, 70, 2014
4D1O
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STRUCTURE OF HUMAN ENDOTHELIAL NITRIC OXIDE SYNTHASE HEME DOMAIN WITH L-ARG BOUND
Descriptor:NITRIC OXIDE SYNTHASE, ENDOTHELIAL, ARGININE, ...
Authors:Li, H., Poulos, T.L.
Deposit date:2014-05-02
Release date:2014-10-15
Last modified:2014-10-22
Method:X-RAY DIFFRACTION (1.819 Å)
Cite:Structures of Human Constitutive Nitric Oxide Synthases
Acta Crystallogr.,Sect.D, 70, 2014
4D1P
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STRUCTURE OF HUMAN ENDOTHELIAL NITRIC OXIDE SYNTHASE HEME DOMAIN IN COMPLEX WITH 6-((((3S, 5R)-5-(((6-AMINO-4-METHYLPYRIDIN-2-YL)METHOXY) METHYL)PYRROLIDIN-3-YL)OXY) METHYL)-4-METHYLPYRIDIN-2-AMINE
Descriptor:NITRIC OXIDE SYNTHASE, ENDOTHELIAL, PROTOPORPHYRIN IX CONTAINING FE, ...
Authors:Li, H., Poulos, T.L.
Deposit date:2014-05-02
Release date:2014-10-15
Last modified:2014-10-22
Method:X-RAY DIFFRACTION (1.731 Å)
Cite:Structures of Human Constitutive Nitric Oxide Synthases
Acta Crystallogr.,Sect.D, 70, 2014
4G3T
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MYCOBACTERIUM SMEGMATIS DPRE1 - HEXAGONAL CRYSTAL FORM
Descriptor:oxidoreductase DprE1
Authors:Li, H., Jogl, G.
Deposit date:2012-07-15
Release date:2012-12-05
Last modified:2013-08-28
Method:X-RAY DIFFRACTION (2.346 Å)
Cite:Crystal structure of decaprenylphosphoryl-beta- D-ribose 2'-epimerase from Mycobacterium smegmatis.
Proteins, 81, 2013
4G3U
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MYCOBACTERIUM SMEGMATIS DPRE1 - MONOCLINIC CRYSTAL FORM
Descriptor:oxidoreductase DprE1
Authors:Li, H., Jogl, G.
Deposit date:2012-07-15
Release date:2012-12-05
Last modified:2013-08-28
Method:X-RAY DIFFRACTION (2.689 Å)
Cite:Crystal structure of decaprenylphosphoryl-beta- D-ribose 2'-epimerase from Mycobacterium smegmatis.
Proteins, 81, 2013
4LNQ
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CRYSTAL STRUCTURE OF IFI202 HINA DOMAIN IN COMPLEX WITH 20BP DSDNA
Descriptor:Interferon-activable protein 202, 20bp DNA
Authors:Li, H., Wang, Z.-X., Wu, J.-W.
Deposit date:2013-07-12
Release date:2014-01-08
Last modified:2014-02-12
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural mechanism of DNA recognition by the p202 HINa domain: insights into the inhibition of Aim2-mediated inflammatory signalling.
Acta Crystallogr F Struct Biol Commun, 70, 2014
5E6F
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CANARYPOX VIRUS RESOLVASE
Descriptor:CNPV261 Holliday junction resolvase protein, MAGNESIUM ION, D(-)-TARTARIC ACID
Authors:Li, H., Hwang, Y., Perry, K., Bushman, F.D., Van Duyne, G.D.
Deposit date:2015-10-09
Release date:2016-03-30
Last modified:2017-09-27
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structure and Metal Binding Properties of a Poxvirus Resolvase.
J.Biol.Chem., 291, 2016
5FMG
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STRUCTURE AND FUNCTION BASED DESIGN OF PLASMODIUM-SELECTIVE PROTEASOME INHIBITORS
Descriptor:PROTEASOME SUBUNIT ALPHA, PUTATIVE, PROTEASOME SUBUNIT ALPHA TYPE 2, ...
Authors:Li, H., O'Donoghue, A.J., van der Linden, W.A., Xie, S.C., Yoo, E., Foe, I.T., Tilley, L., Craik, C.S., da Fonseca, P.C.A., Bogyo, M.
Deposit date:2015-11-04
Release date:2016-03-02
Last modified:2017-08-23
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Structure and Function Based Design of Plasmodium-Selective Proteasome Inhibitors
Nature, 530, 2016
5GRQ
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CRYSTAL STRUCTURE OF DHB DOMAIN OF DAXX IN COMPLEX WITH AN ATRX PEPTIDE
Descriptor:Death domain-associated protein 6, Transcriptional regulator ATRX, ACETATE ION, ...
Authors:Li, H.
Deposit date:2016-08-12
Release date:2017-09-27
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (1.584 Å)
Cite:Crystal Structure of DHB domain of Daxx in complex with an ATRX peptide
To be published
5HU4
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CYSTAL STRUCTURE OF LISTERIA MONOCYTOGENES SORTASE A
Descriptor:Cysteine protease
Authors:Li, H.
Deposit date:2016-01-27
Release date:2017-02-01
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Inhibition of sortase A by chalcone prevents Listeria monocytogenes infection.
Biochem. Pharmacol., 106, 2016
5J8R
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CRYSTAL STRUCTURE OF THE CATALYTIC DOMAIN OF HUMAN PROTEIN TYROSINE PHOSPHATASE NON-RECEPTOR TYPE 12 - K61R MUTANT
Descriptor:Tyrosine-protein phosphatase non-receptor type 12
Authors:Li, H., Yang, F., Xu, Y.F., Wang, W.J., Xiao, P., Yu, X., Sun, J.P.
Deposit date:2016-04-08
Release date:2016-04-27
Last modified:2016-05-18
Method:X-RAY DIFFRACTION (2.043 Å)
Cite:Crystal structure and substrate specificity of PTPN12.
Cell Rep, 15, 2016
6CIC
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STRUCTURE OF THE HUMAN NITRIC OXIDE SYNTHASE R354A/G357D MUTANT HEME DOMAIN IN COMPLEX WITH N-(1-(2-(ETHYL(METHYL)AMINO)ETHYL)-1,2,3,4-TETRAHYDROQUINO-LIN-6-YL)THIOPHENE-2-CARBOXIMIDAMIDE
Descriptor:Nitric oxide synthase, brain, PROTOPORPHYRIN IX CONTAINING FE, ...
Authors:Li, H., Poulos, T.L.
Deposit date:2018-02-23
Release date:2018-10-31
Last modified:2018-11-21
Method:X-RAY DIFFRACTION (1.752 Å)
Cite:Structural Basis for Isoform Selective Nitric Oxide Synthase Inhibition by Thiophene-2-carboximidamides.
Biochemistry, 57, 2018
6CID
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STRUCTURE OF HUMAN NEURONAL NITRIC OXIDE SYNTHASE R354A/G357D MUTANT HEME DOMAIN IN COMPLEX WITH N-(1-(PIPERIDIN-4-YL)INDOLIN-5-YL)THIOPHENE-2-CARBOXIMIDAMIDE
Descriptor:Nitric oxide synthase, brain, PROTOPORPHYRIN IX CONTAINING FE, ...
Authors:Li, H., Poulos, T.L.
Deposit date:2018-02-23
Release date:2018-10-31
Last modified:2019-02-20
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Structural Basis for Isoform Selective Nitric Oxide Synthase Inhibition by Thiophene-2-carboximidamides.
Biochemistry, 57, 2018
6DNW
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SEQUENCE REQUIREMENTS OF THE LISTERIA INNOCUA PROPHAGE ATTP SITE
Descriptor:Putative integrase [Bacteriophage A118], DNA (26-MER), ZINC ION
Authors:Li, H., Sharp, R., Rutherford, K., Gupta, K., Van Duyne, G.D.
Deposit date:2018-06-08
Release date:2018-10-03
Last modified:2018-10-24
Method:X-RAY DIFFRACTION (2.849 Å)
Cite:Serine Integrase attP Binding and Specificity.
J. Mol. Biol., 430, 2018
6EDQ
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CRYSTAL STRUCTURE OF THE LIGHT-GATED ANION CHANNELRHODOPSIN GTACR1
Descriptor:Anion channelrhodopsin 1, (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, GLYCEROL
Authors:Li, H., Huang, C.Y., Wang, M., Zheng, L., Spudich, J.L.
Deposit date:2018-08-10
Release date:2019-01-16
Last modified:2019-01-23
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Crystal structure of a natural light-gated anion channelrhodopsin.
Elife, 8, 2019
4TMP
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CRYSTAL STRUCTURE OF AF9 YEATS BOUND TO H3K9AC PEPTIDE
Descriptor:Protein AF-9, ALA-ARG-THR-LYS-GLN-THR-ALA-ARG-ALY-SER-THR, 1,2-ETHANEDIOL
Authors:Li, H., Li, Y., Wang, H., Ren, Y.
Deposit date:2014-06-02
Release date:2014-11-05
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:AF9 YEATS Domain Links Histone Acetylation to DOT1L-Mediated H3K79 Methylation.
Cell, 159, 2014
5B73
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CRYSTAL STRUCTURE OF HUMAN ZMYND8 PHD-BROMO-PWWP DOMAIN
Descriptor:Protein kinase C-binding protein 1, ZINC ION
Authors:Li, H., Li, Y., Zheng, X.
Deposit date:2016-06-03
Release date:2016-11-02
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:ZMYND8 Reads the Dual Histone Mark H3K4me1-H3K14ac to Antagonize the Expression of Metastasis-Linked Genes
Mol.Cell, 63, 2016