Author results

3MAR
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CRYSTAL STRUCTURE OF HOMODIMERIC R132H MUTANT OF HUMAN CYTOSOLIC NADP(+)-DEPENDENT ISOCITRATE DEHYDROGENASE IN COMPLEX WITH NADP
分子名称:Isocitrate dehydrogenase [NADP] cytoplasmic, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
著者Yang, B., Peng, Y., Ding, J.
登録日2010-03-24
公開日2010-11-10
最終更新日2014-05-21
実験手法X-RAY DIFFRACTION (3.41 Å)
主引用文献Molecular mechanisms of "off-on switch" of activities of human IDH1 by tumor-associated mutation R132H.
Cell Res., 20, 2010
3MAS
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CRYSTAL STRUCTURE OF HETERODIMERIC R132H MUTANT OF HUMAN CYTOSOLIC NADP(+)-DEPENDENT ISOCITRATE DEHYDROGENASE IN COMPLEX WITH NADP AND ISOCITRATE
分子名称:Isocitrate dehydrogenase [NADP] cytoplasmic, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ISOCITRIC ACID
著者Yang, B., Peng, Y., Ding, J.
登録日2010-03-24
公開日2010-11-10
最終更新日2017-11-08
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Molecular mechanisms of "off-on switch" of activities of human IDH1 by tumor-associated mutation R132H.
Cell Res., 20, 2010
3PPV
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CRYSTAL STRUCTURE OF AN ENGINEERED VWF A2 DOMAIN (N1493C AND C1670S)
分子名称:von Willebrand factor, SULFATE ION, CALCIUM ION
著者Zhou, M., Dong, X., Zhong, C., Ding, J.
登録日2010-11-25
公開日2011-05-04
最終更新日2017-11-08
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献A novel calcium-binding site of von Willebrand factor A2 domain regulates its cleavage by ADAMTS13
Blood, 117, 2011
3PPW
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CRYSTAL STRUCTURE OF THE D1596A MUTANT OF AN ENGINEERED VWF A2 DOMAIN (N1493C AND C1670S)
分子名称:von Willebrand factor, SODIUM ION
著者Zhou, M., Dong, X., Zhong, C., Ding, J.
登録日2010-11-25
公開日2011-05-04
最終更新日2017-11-08
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献A novel calcium-binding site of von Willebrand factor A2 domain regulates its cleavage by ADAMTS13
Blood, 117, 2011
3PPX
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CRYSTAL STRUCTURE OF THE N1602A MUTANT OF AN ENGINEERED VWF A2 DOMAIN (N1493C AND C1670S)
分子名称:von Willebrand factor, SODIUM ION
著者Zhou, M., Dong, X., Zhong, C., Ding, J.
登録日2010-11-25
公開日2011-05-04
最終更新日2017-11-08
実験手法X-RAY DIFFRACTION (1.91 Å)
主引用文献A novel calcium-binding site of von Willebrand factor A2 domain regulates its cleavage by ADAMTS13
Blood, 117, 2011
3PPY
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CRYSTAL STRUCTURE OF THE D1596A/N1602A DOUBLE MUTANT OF AN ENGINEERED VWF A2 DOMAIN (N1493C AND C1670S)
分子名称:von Willebrand factor, SODIUM ION
著者Zhou, M., Dong, X., Zhong, C., Ding, J.
登録日2010-11-25
公開日2011-05-04
最終更新日2017-11-08
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献A novel calcium-binding site of von Willebrand factor A2 domain regulates its cleavage by ADAMTS13
Blood, 117, 2011
3QAH
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CRYSTAL STRUCTURE OF APO-FORM HUMAN MOF CATALYTIC DOMAIN
分子名称:Probable histone acetyltransferase MYST1, ZINC ION
著者Sun, B., Tang, Q., Zhong, C., Ding, J.
登録日2011-01-11
公開日2011-07-06
最終更新日2013-06-26
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Regulation of the histone acetyltransferase activity of hMOF via autoacetylation of Lys274
Cell Res., 21, 2011
3RIB
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HUMAN LYSINE METHYLTRANSFERASE SMYD2 IN COMPLEX WITH ADOHCY
分子名称:N-lysine methyltransferase SMYD2, ZINC ION, S-ADENOSYL-L-HOMOCYSTEINE, ...
著者Xu, S., Zhang, T., Zhong, C., Ding, J.
登録日2011-04-13
公開日2011-07-20
最終更新日2017-11-08
実験手法X-RAY DIFFRACTION (2.79 Å)
主引用文献Structure of human lysine methyltransferase Smyd2 reveals insights into the substrate divergence in Smyd proteins
J Mol Cell Biol, 3, 2011
3RPN
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CRYSTAL STRUCTURE OF HUMAN KAPPA CLASS GLUTATHIONE TRANSFERASE IN COMPLEX WITH S-HEXYLGLUTATHIONE
分子名称:Glutathione S-transferase kappa 1, S-HEXYLGLUTATHIONE
著者Wang, B., Peng, Y., Zhang, T., Ding, J.
登録日2011-04-27
公開日2011-07-13
最終更新日2017-11-08
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal structures and kinetic studies of human Kappa class glutathione transferase provide insights into the catalytic mechanism.
Biochem.J., 439, 2011
3RPP
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CRYSTAL STRUCTURE OF HUMAN KAPPA CLASS GLUTATHIONE TRANSFERASE IN APO FORM
分子名称:Glutathione S-transferase kappa 1
著者Wang, B., Peng, Y., Zhang, T., Ding, J.
登録日2011-04-27
公開日2011-07-13
最終更新日2017-11-08
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystal structures and kinetic studies of human Kappa class glutathione transferase provide insights into the catalytic mechanism.
Biochem.J., 439, 2011
3SP4
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CRYSTAL STRUCTURE OF APRATAXIN ORTHOLOG HNT3 FROM SCHIZOSACCHAROMYCES POMBE
分子名称:Aprataxin-like protein, ZINC ION, SULFATE ION
著者Gong, Y., Zhu, D., Ding, J., Dou, C., Ren, X., Jiang, T., Wang, D.
登録日2011-07-01
公開日2011-10-12
最終更新日2013-07-03
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystal structures of aprataxin ortholog Hnt3 reveal the mechanism for reversal of 5'-adenylated DNA
Nat.Struct.Mol.Biol., 18, 2011
3SPD
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CRYSTAL STRUCTURE OF APRATAXIN ORTHOLOG HNT3 IN COMPLEX WITH DNA
分子名称:Aprataxin-like protein, DNA (5'-D(*TP*AP*TP*TP*CP*CP*GP*AP*TP*AP*GP*TP*GP*AP*C)-3'), DNA (5'-D(*GP*TP*CP*AP*CP*TP*AP*TP*CP*GP*GP*AP*AP*TP*GP*AP*G)-3'), ...
著者Gong, Y., Zhu, D., Ding, J., Dou, C., Ren, X., Jiang, T., Wang, D.
登録日2011-07-01
公開日2011-10-12
最終更新日2013-07-03
実験手法X-RAY DIFFRACTION (1.912 Å)
主引用文献Crystal structures of aprataxin ortholog Hnt3 reveal the mechanism for reversal of 5'-adenylated DNA
Nat.Struct.Mol.Biol., 18, 2011
3SPL
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CRYSTAL STRUCTURE OF APRATAXIN ORTHOLOG HNT3 IN COMPLEX WITH DNA AND AMP
分子名称:Aprataxin-like protein, DNA (5'-D(*TP*AP*TP*TP*CP*CP*GP*AP*TP*AP*GP*TP*GP*AP*C)-3'), DNA (5'-D(*GP*TP*CP*AP*CP*TP*AP*TP*CP*GP*GP*AP*AP*TP*GP*AP*G)-3'), ...
著者Gong, Y., Zhu, D., Ding, J., Dou, C., Ren, X., Jiang, T., Wang, D.
登録日2011-07-02
公開日2011-10-12
最終更新日2013-07-03
実験手法X-RAY DIFFRACTION (2.101 Å)
主引用文献Crystal structures of aprataxin ortholog Hnt3 reveal the mechanism for reversal of 5'-adenylated DNA
Nat.Struct.Mol.Biol., 18, 2011
3VPV
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CRYSTAL STRUCTURE OF PSEUDOMONAS AERUGINOSA TSI2
分子名称:Tse2 specific immunity protein 2
著者Wang, W., Ding, J., Wang, D.C.
登録日2012-03-13
公開日2012-03-28
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystal Structure of Pseudomonas aeruginosa Tsi2
To be Published
3W8H
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CRYSTAL STRUCTURE OF CCM3 IN COMPLEX WITH THE C-TERMINAL REGULATORY DOMAIN OF STK25
分子名称:Programmed cell death protein 10, Serine/threonine-protein kinase 25, SULFATE ION
著者Xu, X., Wang, D.C., Ding, J.
登録日2013-03-13
公開日2013-07-03
実験手法X-RAY DIFFRACTION (2.426 Å)
主引用文献Structural Basis for the Unique Heterodimeric Assembly between Cerebral Cavernous Malformation 3 and Germinal Center Kinase III.
Structure, 21, 2013
3W8I
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CRYSTAL STRUCTURE OF CCM3 IN COMPLEX WITH THE C-TERMINAL REGULATORY DOMAIN OF MST4
分子名称:Programmed cell death protein 10, Serine/threonine-protein kinase MST4
著者Xu, X., Wang, D.C., Ding, J.
登録日2013-03-13
公開日2013-07-03
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structural Basis for the Unique Heterodimeric Assembly between Cerebral Cavernous Malformation 3 and Germinal Center Kinase III.
Structure, 21, 2013
4EUE
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CRYSTAL STRUCTURE OF CLOSTRIDIUM ACETOBUTULICUM TRANS-2-ENOYL-COA REDUCTASE IN COMPLEX WITH NADH
分子名称:Putative reductase CA_C0462, 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, SODIUM ION
著者Hu, K., Zhao, M., Zhang, T., Yang, S., Ding, J.
登録日2012-04-25
公開日2012-11-28
最終更新日2013-07-17
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structures of trans-2-enoyl-CoA reductases from Clostridium acetobutylicum and Treponema denticola: insights into the substrate specificity and the catalytic mechanism
Biochem.J., 449, 2013
4EUF
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CRYSTAL STRUCTURE OF CLOSTRIDIUM ACETOBUTULICUM TRANS-2-ENOYL-COA REDUCTASE IN COMPLEX WITH NAD
分子名称:Putative reductase CA_C0462, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, SODIUM ION
著者Hu, K., Zhao, M., Zhang, T., Yang, S., Ding, J.
登録日2012-04-25
公開日2012-11-28
最終更新日2013-07-17
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structures of trans-2-enoyl-CoA reductases from Clostridium acetobutylicum and Treponema denticola: insights into the substrate specificity and the catalytic mechanism
Biochem.J., 449, 2013
4EUH
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CRYSTAL STRUCTURE OF CLOSTRIDIUM ACETOBUTULICUM TRANS-2-ENOYL-COA REDUCTASE APO FORM
分子名称:Putative reductase CA_C0462, SODIUM ION
著者Hu, K., Zhao, M., Zhang, T., Yang, S., Ding, J.
登録日2012-04-25
公開日2012-11-28
最終更新日2013-07-17
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structures of trans-2-enoyl-CoA reductases from Clostridium acetobutylicum and Treponema denticola: insights into the substrate specificity and the catalytic mechanism
Biochem.J., 449, 2013
4FBG
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CRYSTAL STRUCTURE OF TREPONEMA DENTICOLA TRANS-2-ENOYL-COA REDUCTASE IN COMPLEX WITH NAD
分子名称:Putative reductase TDE_0597, NICOTINAMIDE-ADENINE-DINUCLEOTIDE
著者Hu, K., Zhao, M., Zhang, T., Yang, S., Ding, J.
登録日2012-05-23
公開日2012-11-28
最終更新日2013-07-17
実験手法X-RAY DIFFRACTION (3.02 Å)
主引用文献Structures of trans-2-enoyl-CoA reductases from Clostridium acetobutylicum and Treponema denticola: insights into the substrate specificity and the catalytic mechanism
Biochem.J., 449, 2013
4FTX
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CRYSTAL STRUCTURE OF EGO3 HOMODIMER
分子名称:Protein SLM4, SUCCINIC ACID
著者Zhang, T., Peli-Gulli, M.P., Yang, H., De Virgilio, C., Ding, J.
登録日2012-06-28
公開日2012-11-28
最終更新日2013-09-04
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Ego3 functions as a homodimer to mediate the interaction between Gtr1-Gtr2 and Ego1 in the ego complex to activate TORC1.
Structure, 20, 2012
4FUW
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CRYSTAL STRUCTURE OF EGO3 MUTANT
分子名称:Protein SLM4, SULFATE ION
著者Zhang, T., Peli-Gulli, M.P., Yang, H., De Virgilio, C., Ding, J.
登録日2012-06-28
公開日2012-11-28
最終更新日2013-09-04
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Ego3 functions as a homodimer to mediate the interaction between Gtr1-Gtr2 and Ego1 in the ego complex to activate TORC1.
Structure, 20, 2012
4HKF
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CRYSTAL STRUCTURE OF DANIO RERIO MEC-17 CATALYTIC DOMAIN IN COMPLEX WITH ACETYL-COA
分子名称:Alpha-tubulin N-acetyltransferase, ACETYL COENZYME *A, SULFATE ION
著者Li, W., Zhong, C., Sun, B., Xu, S., Zhang, T., Ding, J.
登録日2012-10-15
公開日2012-12-12
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Molecular basis of the acetyltransferase activity of MEC-17 towards alpha- tubulin
Cell Res., 22, 2012
4M6W
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CRYSTAL STRUCTURE OF THE C-TERMINAL SEGMENT OF FANCM IN COMPLEX WITH FAAP24
分子名称:Fanconi anemia group M protein, Fanconi anemia-associated protein of 24 kDa, SULFATE ION
著者Yang, H., Zhang, T., Tong, L., Ding, J.
登録日2013-08-11
公開日2013-10-02
最終更新日2015-06-17
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Structural insights into the functions of the FANCM-FAAP24 complex in DNA repair.
Nucleic Acids Res., 41, 2013
4RL0
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STRUCTURAL AND MECHANISTIC INSIGHTS INTO NDM-1 CATALYZED HYDROLYSIS OF CEPHALOSPORINS
分子名称:Beta-lactamase NDM-1, ZINC ION, (2R,5S)-5-[(carbamoyloxy)methyl]-2-[(R)-carboxy{[(2Z)-2-(furan-2-yl)-2-(methoxyimino)acetyl]amino}methyl]-5,6-dihydro-2H-1,3-thiazine-4-carboxylic acid
著者Feng, H., Ding, J., Zhu, D., Liu, X., Xu, X., Zhang, Y., Zang, S., Wang, D.-C., Liu, W.
登録日2014-10-14
公開日2014-11-19
実験手法X-RAY DIFFRACTION (1.3 Å)
主引用文献Structural and Mechanistic Insights into NDM-1 Catalyzed Hydrolysis of Cephalosporins.
J.Am.Chem.Soc., 136, 2014