Author results

5YNW
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CRYSTAL STRUCTURE OF AN AROMATIC PRENYLTRANSFERASE FAMD1 FROM FISCHERELLA AMBIGUA UTEX 1903 IN COMPLEX WITH DMASPP AND INN
分子名称:aromatic prenyltransferase, DIMETHYLALLYL S-THIOLODIPHOSPHATE, GLYCEROL, ...
著者Wang, J., Liu, W.D., Chen, C.C., Guo, R.T.
登録日2017-10-25
公開日2018-08-29
最終更新日2019-10-16
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Structural insight into a novel indole prenyltransferase in hapalindole-type alkaloid biosynthesis.
Biochem. Biophys. Res. Commun., 495, 2018
5Z11
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CRYSTAL STRUCTURE OF GRASS CARP CD8 ALPHA ALPHA HOMODIMERS
分子名称:CD8 alpha chain
著者Wang, J.
登録日2017-12-22
公開日2018-04-11
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Crystal Structure of the Grass Carp CD8 alpha alpha Homodimers Indicates a Dramatic Evolution of CD8 from Ectotherms to Endotherms.
To Be Published
6BIE
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MISREADING CHAPERONE-SUBSTRATE COMPLEXES FROM RANDOM NOISE
分子名称:Periplasmic chaperone Spy, ZINC ION, CHLORIDE ION, ...
著者WANG, J.
登録日2017-11-01
公開日2018-10-17
最終更新日2019-02-20
実験手法X-RAY DIFFRACTION (1.77 Å)
主引用文献Misreading chaperone-substrate complexes from random noise.
Nat. Struct. Mol. Biol., 25, 2018
6CWE
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STRUCTURE OF ALPHA-GSA[8,6P] BOUND BY CD1D AND IN COMPLEX WITH THE VA14VB8.2 TCR
分子名称:Antigen-presenting glycoprotein CD1d1, Beta-2-microglobulin, Chimeric T cell antigen receptor alpha chain Va14,Va24,Ja18, ...
著者Wang, J., Zajonc, D.
登録日2018-03-30
公開日2019-04-03
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Glycolipid recognition by iNKT cells
To Be Published
6HK6
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HUMAN RIOK2 BOUND TO INHIBITOR
分子名称:Serine/threonine-protein kinase RIO2, 2-naphthalen-2-yl-~{N}-pyridin-2-yl-ethanamide, CHLORIDE ION, ...
著者Wang, J., Krojer, T., Bountra, C., Edwards, A.M., Arrowsmith, C., Knapp, S., Elkins, J.M.
登録日2018-09-05
公開日2018-10-24
最終更新日2019-10-02
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Crystal structure of human RIOK2 bound to a specific inhibitor.
Open Biology, 9, 2019
6MNZ
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CRYSTAL STRUCTURE OF RIBBX, A TWO DOMAIN 3,4-DIHYDROXY-2-BUTANONE 4-PHOSPHATE SYNTHASE FROM A. BAUMANNII.
分子名称:3,4-dihydroxy-2-butanone 4-phosphate synthase, SULFATE ION, CHLORIDE ION
著者Wang, J., Gonzalez-Gutierrez, G., Giedroc, D.P.
登録日2018-10-03
公開日2019-04-17
最終更新日2019-05-29
実験手法X-RAY DIFFRACTION (2.66 Å)
主引用文献Multi-metal Restriction by Calprotectin Impacts De Novo Flavin Biosynthesis in Acinetobacter baumannii.
Cell Chem Biol, 26, 2019
6J5T
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RECONSTITUTION AND STRUCTURE OF A PLANT NLR RESISTOSOME CONFERRING IMMUNITY
分子名称:Probable serine/threonine-protein kinase PBL2, Protein kinase superfamily protein, Disease resistance RPP13-like protein 4, ...
著者Wang, J.Z., Wang, J., Hu, M.J., Wang, H.W., Zhou, J.M., Chai, J.J.
登録日2019-01-12
公開日2019-03-20
最終更新日2019-04-17
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Reconstitution and structure of a plant NLR resistosome conferring immunity.
Science, 364, 2019
6J5U
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LIGAND-TRIGGERED ALLOSTERIC ADP RELEASE PRIMES A PLANT NLR COMPLEX
分子名称:Disease resistance RPP13-like protein 4, Probable serine/threonine-protein kinase PBL2, Protein kinase superfamily protein, ...
著者Wang, J.Z., Wang, J., Meijuan, H., Wang, H.W., Zhou, J.M., Chai, J.J.
登録日2019-01-12
公開日2019-04-03
最終更新日2019-11-06
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献Ligand-triggered allosteric ADP release primes a plant NLR complex.
Science, 364, 2019
6J5V
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LIGAND-TRIGGERED ALLOSTERIC ADP RELEASE PRIMES A PLANT NLR COMPLEX
分子名称:Disease resistance RPP13-like protein 4, Probable serine/threonine-protein kinase PBL2, Protein kinase superfamily protein, ...
著者Wang, J.Z., Wang, J., Hu, M.J., Wang, H.W., Zhou, J.M., Chai, J.J.
登録日2019-01-12
公開日2019-04-03
最終更新日2019-11-06
実験手法ELECTRON MICROSCOPY (4.25 Å)
主引用文献Ligand-triggered allosteric ADP release primes a plant NLR complex.
Science, 364, 2019
6J5W
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LIGAND-TRIGGERED ALLOSTERIC ADP RELEASE PRIMES A PLANT NLR COMPLEX
分子名称:RKS1, Disease resistance RPP13-like protein 4, ADENOSINE-5'-DIPHOSPHATE
著者Wang, J.Z., Wang, J., Hu, M.J., Wang, H.W., Zhou, J.M., Chai, J.J.
登録日2019-01-12
公開日2019-04-03
最終更新日2019-04-17
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Ligand-triggered allosteric ADP release primes a plant NLR complex.
Science, 364, 2019
6J6I
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RECONSTITUTION AND STRUCTURE OF A PLANT NLR RESISTOSOME CONFERRING IMMUNITY
分子名称:Probable serine/threonine-protein kinase PBL2, Protein kinase superfamily protein, Disease resistance RPP13-like protein 4, ...
著者Wang, J.Z., Wang, J., Hu, M.J., Wang, H.W., Zhou, J.M., Chai, J.J.
登録日2019-01-15
公開日2019-03-20
最終更新日2019-04-17
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Reconstitution and structure of a plant NLR resistosome conferring immunity.
Science, 364, 2019
3CFO
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TRIPLE MUTANT APO STRUCTURE
分子名称:DNA polymerase, SULFATE ION, GUANOSINE
著者Wang, J., Klimenko, D., Wang, M., Steitz, T.A., Konigsberg, W.H.
登録日2008-03-04
公開日2009-03-10
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Insights into base selectivity from the structures of an RB69 DNA Polymerase triple mutant
To be Published
3CFP
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STRUCTURE OF THE REPLICATING COMPLEX OF A POL ALPHA FAMILY DNA POLYMERASE, TERNARY COMPLEX 1
分子名称:DNA (5'-D(*DAP*DCP*DAP*DGP*DGP*DTP*DAP*DAP*DGP*DCP*DAP*DGP*DTP*DCP*DCP*DGP*DCP*DG)-3'), DNA (5'-D(*DGP*DCP*DGP*DGP*DAP*DCP*DTP*DGP*DCP*DTP*DTP*DAP*DCP*(DOC))-3'), DNA polymerase, ...
著者Wang, J., Klimenko, D., Wang, M., Steitz, T.A., Konigsberg, W.H.
登録日2008-03-04
公開日2009-03-10
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Insights into base selectivity from the structures of an RB69 DNA Polymerase triple mutant
To be Published
3CFR
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STRUCTURE OF THE REPLICATING COMPLEX OF A POL ALPHA FAMILY DNA POLYMERASE, TERNARY COMPLEX 2
分子名称:DNA (5'-D(*DTP*DCP*DAP*DAP*DGP*DTP*DAP*DAP*DGP*DCP*DAP*DGP*DTP*DCP*DCP*DGP*DCP*DG)-3'), DNA (5'-D(*DGP*DCP*DGP*DGP*DAP*DCP*DTP*DGP*DCP*DTP*DTP*DAP*(DOC))-3'), DNA polymerase, ...
著者Wang, J., Klimenko, D., Wang, M., Steitz, T.A., Konigsberg, W.H.
登録日2008-03-04
公開日2009-03-10
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Insights into base selectivity from the structures of an RB69 DNA Polymerase triple mutant
To be Published
5GQH
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CRYO-EM STRUCTURE OF PAECAS3-ACRF3 COMPLEX
分子名称:CRISPR-associated nuclease/helicase Cas3 subtype I-F/YPEST, anti-CRISPR protein 3
著者Zhang, X., Ma, J., Wang, Y., Wang, J.
登録日2016-08-07
公開日2016-09-21
最終更新日2019-11-06
実験手法ELECTRON MICROSCOPY (4.2 Å)
主引用文献A CRISPR evolutionary arms race: structural insights into viral anti-CRISPR/Cas responses
Cell Res., 26, 2016
3OSY
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HUMAN ENTEROVIRUS 71 3C PROTEASE
分子名称:3C protease
著者Wang, J., Fan, T., Wang, M., Cui, S.
登録日2010-09-10
公開日2011-03-23
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.9923 Å)
主引用文献Crystal Structure of Human Enterovirus 71 3C Protease.
J.Mol.Biol., 408, 2011
4KNB
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C-MET IN COMPLEX WITH OSI LIGAND
分子名称:Hepatocyte growth factor receptor, 7-[(1R)-1-(2,6-dichloro-3-fluorophenyl)ethoxy]-3-[1-(piperidin-4-yl)-1H-pyrazol-4-yl]furo[3,2-c]pyridin-6-amine, GAMMA-BUTYROLACTONE
著者Wang, J., Steinig, A.G., Li, A.H., Chen, X., Dong, H., Ferraro, C., Jin, M., Kadalbajoo, M., Kleinberg, A., Stolz, K.M., Tavares-Greco, P.A., Wang, T., Albertella, M.R., Peng, Y., Crew, L., Kahler, J.
登録日2013-05-09
公開日2014-04-30
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Novel 6-aminofuro[3,2-c]pyridines as potent, orally efficacious inhibitors of cMET and RON kinases.
Bioorg.Med.Chem.Lett., 23, 2013
5UFL
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CRYSTAL STRUCTURE OF A CIP2A CORE DOMAIN
分子名称:Protein CIP2A, ZINC ION
著者Wang, Z., Wang, J., Rao, Z., Xu, W.
登録日2017-01-04
公開日2017-02-15
最終更新日2017-11-22
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Oncoprotein CIP2A is stabilized via interaction with tumor suppressor PP2A/B56.
EMBO Rep., 18, 2017
5UY8
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CRYSTAL STRUCTURE OF AICARFT BOUND TO AN ANTIFOLATE
分子名称:Bifunctional purine biosynthesis protein PURH, 5-[(5S)-5-ethyl-5-methyl-6-oxo-1,4,5,6-tetrahydropyridin-3-yl]-N-(6-fluoro-1-oxo-1,2-dihydroisoquinolin-7-yl)thiophene-2-sulfonamide, AMINOIMIDAZOLE 4-CARBOXAMIDE RIBONUCLEOTIDE, ...
著者Wang, J., Wang, Y., Fales, K.R., Atwell, S., Clawson, D.
登録日2017-02-23
公開日2018-01-10
実験手法X-RAY DIFFRACTION (2.39 Å)
主引用文献Discovery of N-(6-Fluoro-1-oxo-1,2-dihydroisoquinolin-7-yl)-5-[(3R)-3-hydroxypyrrolidin-1-yl]thiophene-2-sulfonamide (LSN 3213128), a Potent and Selective Nonclassical Antifolate Aminoimidazole-4-carboxamide Ribonucleotide Formyltransferase (AICARFT) Inhibitor Effective at Tumor Suppression in a Cancer Xenograft Model.
J. Med. Chem., 60, 2017
4HJR
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CRYSTAL STRUCTURE OF F2YRS
分子名称:Tyrosine-tRNA ligase
著者Wang, J., Tian, C., Gong, W., Li, F., Shi, P., Li, J., Ding, W.
登録日2012-10-13
公開日2013-03-13
最終更新日2013-05-22
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献A genetically encoded 19F NMR probe for tyrosine phosphorylation.
Angew.Chem.Int.Ed.Engl., 52, 2013
4HJX
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CRYSTAL STRUCTURE OF F2YRS COMPLEXED WITH F2Y
分子名称:Tyrosine-tRNA ligase, 3,5-difluoro-L-tyrosine
著者Wang, J., Tian, C., Gong, W., Li, F., Shi, P., Li, J., Ding, W.
登録日2012-10-14
公開日2013-03-13
最終更新日2018-03-14
実験手法X-RAY DIFFRACTION (2.91 Å)
主引用文献A genetically encoded 19F NMR probe for tyrosine phosphorylation.
Angew.Chem.Int.Ed.Engl., 52, 2013
4Z5W
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THE PLANT PEPTIDE HORMONE RECEPTOR
分子名称:Phytosulfokine receptor 1, Phytosulfokine, N-ACETYL-D-GLUCOSAMINE
著者Chai, J., Wang, J., Han, Z.
登録日2015-04-03
公開日2016-03-02
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Allosteric receptor activation by the plant peptide hormone phytosulfokine
Nature, 525, 2015
4Z61
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THE PLANT PEPTIDE HORMONE RECEPTOR COMPLEX
分子名称:Phytosulfokine receptor 1, Somatic embryogenesis receptor kinase 2, PTR-ILE-PTR-THR-GLN, ...
著者Chai, J., Wang, J.
登録日2015-04-03
公開日2016-03-02
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献Allosteric receptor activation by the plant peptide hormone phytosulfokine
Nature, 525, 2015
4Z62
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THE PLANT PEPTIDE HORMONE FREE RECEPTOR
分子名称:Phytosulfokine receptor 1, N-ACETYL-D-GLUCOSAMINE
著者Chai, J., Wang, J., Han, Z.
登録日2015-04-03
公開日2016-03-02
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Allosteric receptor activation by the plant peptide hormone phytosulfokine
Nature, 525, 2015
4Z63
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THE PLANT PEPTIDE HORMONE RECEPTOR IN ARABIDOPSIS
分子名称:Phytosulfokine receptor 1, Phytosulfokine, N-ACETYL-D-GLUCOSAMINE
著者Chai, J., Wang, J., Han, Z.
登録日2015-04-03
公開日2016-03-02
実験手法X-RAY DIFFRACTION (2.514 Å)
主引用文献Allosteric receptor activation by the plant peptide hormone phytosulfokine
Nature, 525, 2015