Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help
Search by PDB author
1UDI
DownloadVisualize
BU of 1udi by Molmil
NUCLEOTIDE MIMICRY IN THE CRYSTAL STRUCTURE OF THE URACIL-DNA GLYCOSYLASE-URACIL GLYCOSYLASE INHIBITOR PROTEIN COMPLEX
Descriptor: URACIL-DNA GLYCOSYLASE, URACIL-DNA GLYCOSYLASE INHIBITOR PROTEIN
Authors:Pearl, L.H, Savva, R.
Deposit date:1995-10-30
Release date:1996-03-08
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Nucleotide mimicry in the crystal structure of the uracil-DNA glycosylase-uracil glycosylase inhibitor protein complex.
Nat.Struct.Biol., 2, 1995
1QNL
DownloadVisualize
BU of 1qnl by Molmil
AMIDE RECEPTOR/NEGATIVE REGULATOR OF THE AMIDASE OPERON OF PSEUDOMONAS AERUGINOSA (AMIC) COMPLEXED WITH BUTYRAMIDE
Descriptor: ALIPHATIC AMIDASE EXPRESSION-REGULATING PROTEIN, BUTYRAMIDE
Authors:Pearl, L.H, O'Hara, B.P, Roe, S.M.
Deposit date:1999-10-19
Release date:1999-12-23
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural Adaptation to Selective Pressure for Altered Ligand Specificity in the Pseudomonas Aeruginosa Amide Receptor, Amic
Protein Eng., 13, 2000
1QO0
DownloadVisualize
BU of 1qo0 by Molmil
Amide receptor of the amidase operon of Pseudomonas aeruginosa (AmiC) complexed with the negative regulator AmiR.
Descriptor: AMIC, AMIR, BUTYRAMIDE
Authors:Pearl, L.H, O'Hara, B.P, Roe, S.M.
Deposit date:1999-10-26
Release date:1999-12-23
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Crystal Structure and Induction Mechanism of Amic-Amir: A Ligand-Regulated Transcription Antitermination Complex
Embo J., 18, 1999
1UDH
DownloadVisualize
BU of 1udh by Molmil
THE STRUCTURAL BASIS OF SPECIFIC BASE EXCISION REPAIR BY URACIL-DNA GLYCOSYLASE
Descriptor: SULFATE ION, URACIL, URACIL-DNA GLYCOSYLASE
Authors:Pearl, L.H, Savva, R.
Deposit date:1995-10-30
Release date:1996-03-08
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:The structural basis of specific base-excision repair by uracil-DNA glycosylase.
Nature, 373, 1995
1UDG
DownloadVisualize
BU of 1udg by Molmil
THE STRUCTURAL BASIS OF SPECIFIC BASE EXCISION REPAIR BY URACIL-DNA GLYCOSYLASE
Descriptor: SULFATE ION, URACIL-DNA GLYCOSYLASE
Authors:Pearl, L.H, Savva, R.
Deposit date:1995-06-23
Release date:1996-01-29
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:The structural basis of specific base-excision repair by uracil-DNA glycosylase.
Nature, 373, 1995
1PEA
DownloadVisualize
BU of 1pea by Molmil
AMIDE RECEPTOR/NEGATIVE REGULATOR OF THE AMIDASE OPERON OF PSEUDOMONAS AERUGINOSA (AMIC) COMPLEXED WITH ACETAMIDE
Descriptor: ACETAMIDE, AMIDASE OPERON
Authors:Pearl, L.H, O'Hara, B.P.
Deposit date:1995-11-16
Release date:1996-04-03
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structure of AmiC: the controller of transcription antitermination in the amidase operon of Pseudomonas aeruginosa.
EMBO J., 13, 1994
1AM1
DownloadVisualize
BU of 1am1 by Molmil
ATP BINDING SITE IN THE HSP90 MOLECULAR CHAPERONE
Descriptor: ADENOSINE-5'-DIPHOSPHATE, HEAT SHOCK PROTEIN 90
Authors:Pearl, L.H, Roe, S.M, Prodromou, C.
Deposit date:1997-06-20
Release date:1998-06-24
Last modified:2023-08-02
Method:X-RAY DIFFRACTION (2 Å)
Cite:Identification and structural characterization of the ATP/ADP-binding site in the Hsp90 molecular chaperone
Cell(Cambridge,Mass.), 90, 1997
1AMW
DownloadVisualize
BU of 1amw by Molmil
ADP BINDING SITE IN THE HSP90 MOLECULAR CHAPERONE
Descriptor: ADENOSINE-5'-DIPHOSPHATE, HEAT SHOCK PROTEIN 90
Authors:Pearl, L.H, Roe, S.M, Prodromou, C.
Deposit date:1997-06-19
Release date:1998-06-24
Last modified:2023-08-02
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Identification and structural characterization of the ATP/ADP-binding site in the Hsp90 molecular chaperone
Cell(Cambridge,Mass.), 90, 1997
1GOW
DownloadVisualize
BU of 1gow by Molmil
BETA-GLYCOSIDASE FROM SULFOLOBUS SOLFATARICUS
Descriptor: BETA-GLYCOSIDASE
Authors:Pearl, L.H, Aguilar, C.F, Sanderson, I.
Deposit date:1996-09-19
Release date:1997-08-20
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal structure of the beta-glycosidase from the hyperthermophilic archeon Sulfolobus solfataricus: resilience as a key factor in thermostability.
J.Mol.Biol., 271, 1997
1LAU
DownloadVisualize
BU of 1lau by Molmil
URACIL-DNA GLYCOSYLASE
Descriptor: DNA (5'-D(*TP*TP*T)-3'), PROTEIN (URACIL-DNA GLYCOSYLASE (E.C.3.2.2.-))
Authors:Pearl, L.H, Savva, R.
Deposit date:1996-01-03
Release date:1996-06-10
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:The structural basis of specific base-excision repair by uracil-DNA glycosylase.
Nature, 373, 1995
4APE
DownloadVisualize
BU of 4ape by Molmil
THE ACTIVE SITE OF ASPARTIC PROTEINASES
Descriptor: ENDOTHIAPEPSIN
Authors:Pearl, L.H, Sewell, B.T, Jenkins, J.A, Cooper, J.B, Blundell, T.L.
Deposit date:1986-06-09
Release date:1986-07-14
Last modified:2019-10-16
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:The Active Site of Aspartic Proteinases
FEBS Lett., 174, 1984
1GXR
DownloadVisualize
BU of 1gxr by Molmil
WD40 Region of Human Groucho/TLE1
Descriptor: CALCIUM ION, TRANSDUCIN-LIKE ENHANCER PROTEIN 1
Authors:Pearl, L.H, Roe, S.M, Pickles, L.M.
Deposit date:2002-04-10
Release date:2002-06-13
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Crystal Structure of the C-Terminal Wd40 Repeat Domain of the Human Groucho/Tle1 Transcriptional Corepressor
Structure, 10, 2002
7Z6H
DownloadVisualize
BU of 7z6h by Molmil
Structure of DNA-bound human RAD17-RFC clamp loader and 9-1-1 checkpoint clamp
Descriptor: Cell cycle checkpoint control protein RAD9A, Cell cycle checkpoint protein RAD1,Cell cycle checkpoint protein RAD17, Checkpoint protein HUS1, ...
Authors:Day, M, Oliver, A.W, Pearl, L.H.
Deposit date:2022-03-11
Release date:2022-05-04
Last modified:2022-08-31
Method:ELECTRON MICROSCOPY (3.59 Å)
Cite:Structure of the human RAD17-RFC clamp loader and 9-1-1 checkpoint clamp bound to a dsDNA-ssDNA junction.
Nucleic Acids Res., 50, 2022
1BGQ
DownloadVisualize
BU of 1bgq by Molmil
RADICICOL BOUND TO THE ATP BINDING SITE OF THE N-TERMINAL DOMAIN OF THE YEAST HSP90 CHAPERONE
Descriptor: HEAT SHOCK PROTEIN 90, RADICICOL
Authors:Roe, S.M, Prodromou, C, Pearl, L.H.
Deposit date:1998-05-29
Release date:1999-06-08
Last modified:2023-08-02
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural basis for inhibition of the Hsp90 molecular chaperone by the antitumor antibiotics radicicol and geldanamycin.
J.Med.Chem., 42, 1999
8OK2
DownloadVisualize
BU of 8ok2 by Molmil
Bipartite interaction of TOPBP1 with the GINS complex
Descriptor: DNA replication complex GINS protein PSF1, DNA replication complex GINS protein PSF2, DNA replication complex GINS protein PSF3, ...
Authors:Day, M, Oliver, A.W, Pearl, L.H.
Deposit date:2023-03-26
Release date:2024-03-13
Method:ELECTRON MICROSCOPY (4.1 Å)
Cite:TopBP1 utilises a bipartite GINS binding mode to support genome replication.
Nat Commun, 15, 2024
8AG4
DownloadVisualize
BU of 8ag4 by Molmil
Vaccinia C16 protein bound to Ku70/Ku80
Descriptor: Protein C10, X-ray repair cross-complementing protein 5, X-ray repair cross-complementing protein 6
Authors:Rivera-Calzada, A, Arribas-Bosacoma, R, Pearl, L.H, Llorca, O.
Deposit date:2022-07-19
Release date:2022-11-09
Last modified:2022-11-30
Method:ELECTRON MICROSCOPY (2.46 Å)
Cite:Structural basis for the inactivation of cytosolic DNA sensing by the vaccinia virus.
Nat Commun, 13, 2022
8AG3
DownloadVisualize
BU of 8ag3 by Molmil
Vaccinia C16 N-terminal domains
Descriptor: Protein C10
Authors:Rivera-Calzada, A, Arribas-Bosacoma, R, Pearl, L.H, Llorca, O.
Deposit date:2022-07-19
Release date:2022-11-09
Last modified:2022-11-30
Method:ELECTRON MICROSCOPY (3.47 Å)
Cite:Structural basis for the inactivation of cytosolic DNA sensing by the vaccinia virus.
Nat Commun, 13, 2022
8AG5
DownloadVisualize
BU of 8ag5 by Molmil
Vaccinia C16 protein bound to Ku70/Ku80
Descriptor: Ku70-Xrcc6, Protein C10, X-ray repair cross-complementing protein 5
Authors:Rivera-Calzada, A, Arribas-Bosacoma, R, Pearl, L.H, Llorca, O.
Deposit date:2022-07-19
Release date:2022-11-09
Last modified:2022-11-30
Method:ELECTRON MICROSCOPY (3.47 Å)
Cite:Structural basis for the inactivation of cytosolic DNA sensing by the vaccinia virus.
Nat Commun, 13, 2022
7ZR5
DownloadVisualize
BU of 7zr5 by Molmil
CryoEM structure of HSP90-CDC37-BRAF(V600E)-PP5(closed) complex
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Heat shock protein HSP 90-beta, Hsp90 co-chaperone Cdc37, ...
Authors:Oberoi, J, Pearl, L.H.
Deposit date:2022-05-03
Release date:2022-12-14
Last modified:2022-12-21
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:HSP90-CDC37-PP5 forms a structural platform for kinase dephosphorylation.
Nat Commun, 13, 2022
7ZR0
DownloadVisualize
BU of 7zr0 by Molmil
CryoEM structure of HSP90-CDC37-BRAF(V600E) complex.
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Heat shock protein HSP 90-beta, Hsp90 co-chaperone Cdc37, ...
Authors:Oberoi, J, Pearl, L.H.
Deposit date:2022-05-03
Release date:2022-12-14
Last modified:2023-01-11
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:HSP90-CDC37-PP5 forms a structural platform for kinase dephosphorylation.
Nat Commun, 13, 2022
7ZR6
DownloadVisualize
BU of 7zr6 by Molmil
CryoEM structure of HSP90-CDC37-BRAF(V600E)-PP5(open) complex
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Heat shock protein HSP 90-beta, Hsp90 co-chaperone Cdc37, ...
Authors:Oberoi, J, Pearl, L.H.
Deposit date:2022-05-03
Release date:2022-12-28
Method:ELECTRON MICROSCOPY (4.2 Å)
Cite:HSP90-CDC37-PP5 forms a structural platform for kinase dephosphorylation.
Nat Commun, 13, 2022
5LOH
DownloadVisualize
BU of 5loh by Molmil
Kinase domain of human Greatwall
Descriptor: 1,2-ETHANEDIOL, CHLORIDE ION, STAUROSPORINE, ...
Authors:Rajasekaran, M.B, Pearl, L.H, Oliver, A.W.
Deposit date:2016-08-09
Release date:2016-09-07
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:A first generation inhibitor of human Greatwall kinase, enabled by structural and functional characterisation of a minimal kinase domain construct.
Oncotarget, 7, 2016
3G65
DownloadVisualize
BU of 3g65 by Molmil
Crystal Structure of the Human Rad9-Rad1-Hus1 DNA Damage Checkpoint Complex
Descriptor: Cell cycle checkpoint control protein RAD9A, Cell cycle checkpoint protein RAD1, Checkpoint protein HUS1
Authors:Dore, A.S, Kilkenny, M.L, Rzechorzek, N.J, Pearl, L.H.
Deposit date:2009-02-06
Release date:2009-05-26
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Crystal structure of the rad9-rad1-hus1 DNA damage checkpoint complex--implications for clamp loading and regulation.
Mol.Cell, 34, 2009
7OA5
DownloadVisualize
BU of 7oa5 by Molmil
RUVA COMPLEXED TO A HOLLIDAY JUNCTION.
Descriptor: CALCIUM ION, DNA (5'-D(*AP*GP*TP*TP*CP*GP*CP*GP*AP*GP*TP*TP*CP*GP*C)-3'), DNA (5'-D(*AP*GP*TP*TP*CP*GP*CP*GP*CP*GP*CP*GP*AP*AP*CP*T)-3'), ...
Authors:Roe, S.M, Pearl, L.H.
Deposit date:2021-04-19
Release date:2021-04-28
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.378 Å)
Cite:Crystal structure of an octameric RuvA-Holliday junction complex
Molecular Cell, 2, 1998
7P0L
DownloadVisualize
BU of 7p0l by Molmil
Crystal structure of S.pombe Mdb1 BRCT domains in complex with a H2A phosphopeptide
Descriptor: DNA damage response protein Mdb1, Histone H2A-beta
Authors:Day, M, Oliver, A.W, Pearl, L.H.
Deposit date:2021-06-29
Release date:2021-12-01
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.97 Å)
Cite:Phosphorylation-dependent assembly of DNA damage response systems and the central roles of TOPBP1.
DNA Repair (Amst), 108, 2021

217705

PDB entries from 2024-03-27

PDB statisticsPDBj update infoContact PDBjnumon