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4QN7
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CRYSTAL STRUCTURE OF NEURAMNIDASE N7 COMPLEXED WITH OSELTAMIVIR
分子名称:Neuraminidase, CALCIUM ION, N-ACETYL-D-GLUCOSAMINE, ...
著者Sun, X., Li, Q., Wu, Y., Liu, Y., Qi, J., Vavricka, C.J., Gao, G.F.
登録日2014-06-17
公開日2014-07-30
最終更新日2014-08-06
実験手法X-RAY DIFFRACTION (2.302 Å)
主引用文献Structure of influenza virus N7: the last piece of the neuraminidase "jigsaw" puzzle
J.Virol., 2014
4XSQ
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STRUCTURE OF A VARIABLE LYMPHOCYTE RECEPTOR-LIKE PROTEIN BF66946 FROM BRANCHIOSTOMA FLORIDAE
分子名称:variable lymphocyte receptor-like protein Bf66946, 1,2-ETHANEDIOL, GLYCEROL
著者Cao, D.D., Cheng, W., Jiang, Y.L., Wang, W.J., Li, Q., Chen, Y., Zhou, C.Z.
登録日2015-01-22
公開日2016-03-23
実験手法X-RAY DIFFRACTION (1.79 Å)
主引用文献Structure of a variable lymphocyte receptor-like protein from the amphioxus Branchiostoma floridae.
Sci Rep, 6, 2016
5D8W
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STRUCTRUE OF A LUCIDUM PROTEIN
分子名称:Endoglucanase
著者Guo, R., Li, Q., Shang, N., Liu, G., Ko, T.P., Chen, C.C., Liu, W.
登録日2015-08-18
公開日2016-06-29
最終更新日2018-05-23
実験手法X-RAY DIFFRACTION (2.86 Å)
主引用文献Functional and structural analyses of a 1,4-beta-endoglucanase from Ganoderma lucidum.
Enzyme.Microb.Technol., 86, 2016
5D8Z
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STRUCTRUE OF A LUCIDUM PROTEIN
分子名称:endoglucanase, CELLOBIOSE
著者Guo, R., Li, Q., Shang, N., Liu, G., Ko, T.P., Chen, C.C., Liu, W.
登録日2015-08-18
公開日2016-06-29
最終更新日2018-05-23
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Functional and structural analyses of a 1,4-beta-endoglucanase from Ganoderma lucidum.
Enzyme.Microb.Technol., 86, 2016
5XE0
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CRYSTAL STRUCTURE OF EV-D68-3DPOL IN COMPLEX WITH GTP
分子名称:Genome polyprotein, GUANOSINE-5'-TRIPHOSPHATE
著者Xie, W., Wang, C., Wang, Z., Li, Q., Wang, C.
登録日2017-03-30
公開日2017-06-28
最終更新日2018-01-03
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal Structure and Thermostability Characterization of Enterovirus D68 3Dpol
J. Virol., 91, 2017
5YAT
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CRYSTAL STRUCTURE OF MITOCHONDRIAL ALCOHOL DEHYDROGENASE ISOZYME III FROM KOMAGATAELLA PHAFFII GS115
分子名称:Mitochondrial alcohol dehydrogenase isozyme III, GLYCEROL, ISOPROPYL ALCOHOL, ...
著者Zhang, H.D., Li, Q.
登録日2017-09-01
公開日2018-03-21
実験手法X-RAY DIFFRACTION (1.745 Å)
主引用文献Investigation of structure and function of mitochondrial alcohol dehydrogenase isozyme III from Komagataella phaffii GS115.
Biochim. Biophys. Acta, 1862, 2018
6JY5
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STRUCTURE OF CSOS4B FROM HALOTHIOBACILLUS NEAPOLITANUS
分子名称:Unidentified carboxysome polypeptide
著者Zhao, Y.Y., Jiang, Y.L., Chen, Y., Zhou, C.Z., Li, Q.
登録日2019-04-26
公開日2019-06-26
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Crystal structure of pentameric shell protein CsoS4B of Halothiobacillus neapolitanus alpha-carboxysome.
Biochem.Biophys.Res.Commun., 515, 2019
2F7E
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PKA COMPLEXED WITH (S)-2-(1H-INDOL-3-YL)-1-(5-ISOQUINOLIN-6-YL-PYRIDIN-3-YLOXYMETHYL-ETYLAMINE
分子名称:cAMP-dependent protein kinase, alpha-catalytic subunit, PKI inhibitory peptide, ...
著者Stoll, V.S.
登録日2005-11-30
公開日2006-06-27
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Synthesis and structure-activity relationship of 3,4'-bispyridinylethylenes: discovery of a potent 3-isoquinolinylpyridine inhibitor of protein kinase B (PKB/Akt) for the treatment of cancer.
Bioorg.Med.Chem.Lett., 16, 2006
2I1K
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MOESIN FROM SPODOPTERA FRUGIPERDA REVEALS THE COILED-COIL DOMAIN AT 3.0 ANGSTROM RESOLUTION
分子名称:Moesin, CHLORIDE ION, UREA, ...
著者Nance, M.R., Tesmer, J.J.G.
登録日2006-08-14
公開日2006-12-19
最終更新日2017-10-18
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Self-masking in an Intact ERM-merlin Protein: An Active Role for the Central alpha-Helical Domain.
J.Mol.Biol., 365, 2007
3IG9
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SMALL OUTER CAPSID PROTEIN (SOC) OF BACTERIOPHAGE RB69
分子名称:Soc small outer capsid protein, IMIDAZOLE
著者Li, Q., Fokine, A., O'Donnell, E., Rao, V.B., Rossmann, M.G.
登録日2009-07-27
公開日2009-12-08
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structure of the Small Outer Capsid Protein, Soc: A Clamp for Stabilizing Capsids of T4-like Phages
J.Mol.Biol., 395, 2010
3IGE
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SMALL OUTER CAPSID PROTEIN (SOC) FROM BACTERIOPHAGE RB69
分子名称:Soc small outer capsid protein, IMIDAZOLE
著者Li, Q., Fokine, A., O'Donnell, E., Rao, V.B., Rossmann, M.G.
登録日2009-07-27
公開日2009-12-08
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.254 Å)
主引用文献Structure of the Small Outer Capsid Protein, Soc: A Clamp for Stabilizing Capsids of T4-like Phages
J.Mol.Biol., 395, 2010
3OCH
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CHEMICALLY SELF-ASSEMBLED ANTIBODY NANORINGS (CSANS): DESIGN AND CHARACTERIZATION OF AN ANTI-CD3 IGM BIOMIMETIC
分子名称:Dihydrofolate reductase, CHLORIDE ION, (2S,2'S)-5,5'-(nonane-1,9-diyldiimino)bis(2-{[(4-{[(2,4-diaminopteridin-6-yl)methyl](methyl)amino}phenyl)carbonyl]amino}-5-oxopentanoic acid) (non-preferred name), ...
著者Cody, V.
登録日2010-08-10
公開日2010-12-08
最終更新日2018-01-24
実験手法X-RAY DIFFRACTION (1.79 Å)
主引用文献Chemically Self-Assembled Antibody Nanorings (CSANs): Design and Characterization of an Anti-CD3 IgM Biomimetic.
J.Am.Chem.Soc., 132, 2010
5XHZ
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CRYSTAL STRUCTURE ANALYSIS OF CIN85-SH3B IN COMPLEX WITH ARAP1-P2
分子名称:SH3 domain-containing kinase-binding protein 1, Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1, ...
著者Liu, W., Yang, W.
登録日2017-04-25
公開日2018-04-11
最終更新日2018-04-25
実験手法X-RAY DIFFRACTION (1.319 Å)
主引用文献Biochemical and Structural Studies of the Interaction between ARAP1 and CIN85.
Biochemistry, 57, 2018
4U9A
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SULPHUR ANOMALOUS CRYSTAL STRUCTURE OF ASYMMETRIC IRAK4 DIMER
分子名称:Interleukin-1 receptor-associated kinase 4, STAUROSPORINE, SULFATE ION
著者Ferrao, R., Liu, Q., Wu, H.
登録日2014-08-05
公開日2014-09-24
最終更新日2014-10-01
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献IRAK4 Dimerization and trans-Autophosphorylation Are Induced by Myddosome Assembly.
Mol.Cell, 55, 2014
4PV5
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CRYSTAL STRUCTURE OF MOUSE GLYOXALASE I IN COMPLEXED WITH 18-BETA-GLYCYRRHETINIC ACID
分子名称:Lactoylglutathione lyase, ZINC ION, (3BETA,5BETA,14BETA)-3-HYDROXY-11-OXOOLEAN-12-EN-29-OIC ACID
著者Zhang, H., Zhai, J., Zhang, L.P., Zhao, Y.N., Li, C., Hu, X.P.
登録日2014-03-15
公開日2015-03-18
最終更新日2015-09-16
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural basis for 18-beta-glycyrrhetinic acid as a novel non-GSH analog glyoxalase I inhibitor
Acta Pharmacol.Sin., 36, 2015
4U97
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CRYSTAL STRUCTURE OF ASYMMETRIC IRAK4 DIMER
分子名称:Interleukin-1 receptor-associated kinase 4, STAUROSPORINE, SULFATE ION
著者Ferrao, R., Wu, H.
登録日2014-08-05
公開日2014-09-24
最終更新日2014-10-01
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献IRAK4 Dimerization and trans-Autophosphorylation Are Induced by Myddosome Assembly.
Mol.Cell, 55, 2014
2LH0
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NMR STRUCTURE OF THE HISTONE-INTERACTING N-TERMINAL HOMODIMERIC REGION OF RTT106
分子名称:Histone chaperone RTT106
著者Hu, Q., Cui, G., Mer, G.
登録日2011-08-04
公開日2012-02-01
最終更新日2012-03-07
実験手法SOLUTION NMR
主引用文献Structural basis for recognition of H3K56-acetylated histone H3-H4 by the chaperone Rtt106.
Nature, 483, 2012
4KQE
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THE MUTANT STRUCTURE OF THE HUMAN GLYCYL-TRNA SYNTHETASE E71G
分子名称:Glycine--tRNA ligase, GLYCEROL
著者Qin, X., Hao, Z., Tian, Q., Zhang, Z., Zhou, C., Xie, W.
登録日2013-05-15
公開日2014-05-21
最終更新日2016-04-13
実験手法X-RAY DIFFRACTION (2.739 Å)
主引用文献Large Conformational Changes of Insertion 3 in Human Glycyl-tRNA Synthetase (hGlyRS) during Catalysis
J.Biol.Chem., 291, 2016
4L7F
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CO-CRYSTAL STRUCTURE OF JNK1 AND AX13587
分子名称:Mitogen-activated protein kinase 8, N-[1-(4-fluorophenyl)cyclopropyl]-4-[(trans-4-hydroxycyclohexyl)amino]imidazo[1,2-a]quinoxaline-8-carboxamide
著者Walter, R.L., Ranieri, G.M., Riggs, A.M., Weissig, H., Li, B., Shreder, K.R.
登録日2013-06-13
公開日2013-08-21
最終更新日2013-10-09
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Hit-to-lead optimization and kinase selectivity of imidazo[1,2-a]quinoxalin-4-amine derived JNK1 inhibitors.
Bioorg.Med.Chem.Lett., 23, 2013
4LGI
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N-TERMINAL TRUNCATED NLEC STRUCTURE
分子名称:Uncharacterized protein
著者Li, W.Q., Liu, Y.X., Sheng, X.L., Yan, C.Y., Wang, J.W.
登録日2013-06-28
公開日2014-01-15
最終更新日2015-02-25
実験手法X-RAY DIFFRACTION (2.301 Å)
主引用文献Structure and mechanism of a type III secretion protease, NleC
Acta Crystallogr.,Sect.D, 70, 2014
4LGJ
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CRYSTAL STRUCTURE AND MECHANISM OF A TYPE III SECRETION PROTEASE
分子名称:Uncharacterized protein, ZINC ION
著者Li, W.Q., Liu, Y.X., Sheng, X.L., Yan, C.Y., Wang, J.W.
登録日2013-06-28
公開日2014-01-15
最終更新日2015-02-25
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Structure and mechanism of a type III secretion protease, NleC
Acta Crystallogr.,Sect.D, 70, 2014
4X2A
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CRYSTAL STRUCTURE OF MOUSE GLYOXALASE I COMPLEXED WITH BAICALEIN
分子名称:Lactoylglutathione lyase, ZINC ION, 5,6,7-trihydroxy-2-phenyl-4H-chromen-4-one
著者Zhang, H., Zhai, J., Zhang, L., Li, C., Zhao, Y., Hu, X.
登録日2014-11-26
公開日2015-09-16
最終更新日2015-10-28
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献In Vitro Inhibition of Glyoxalase by Flavonoids: New Insights from Crystallographic Analysis
Curr Top Med Chem, 16, 2016
6J1L
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CRYTAL STRUCTURE ANALYSIS OF THE ROR GAMMA(C455E)
分子名称:Nuclear receptor ROR-gamma, 2-[4-(ethylsulfonyl)phenyl]-N-[2'-fluoro-4'-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)[1,1'-biphenyl]-4-yl]acetamide
著者zhang, Y., Li, C.C., wu, X.S.
登録日2018-12-28
公開日2019-05-01
最終更新日2019-05-22
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Discovery and Characterization of XY101, a Potent, Selective, and Orally Bioavailable ROR gamma Inverse Agonist for Treatment of Castration-Resistant Prostate Cancer.
J.Med.Chem., 62, 2019
2R2V
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SEQUENCE DETERMINANTS OF THE TOPOLOGY OF THE LAC REPRESSOR TETRAMERIC COILED COIL
分子名称:GCN4 leucine zipper, ZINC ION, ACETATE ION, ...
著者Liu, J., Lu, M.
登録日2007-08-27
公開日2008-06-17
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Conformational specificity of the lac repressor coiled-coil tetramerization domain.
Biochemistry, 46, 2007
2YFX
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STRUCTURE OF L1196M MUTANT ANAPLASTIC LYMPHOMA KINASE IN COMPLEX WITH CRIZOTINIB
分子名称:TYROSINE-PROTEIN KINASE RECEPTOR, 3-[(1R)-1-(2,6-dichloro-3-fluorophenyl)ethoxy]-5-(1-piperidin-4-yl-1H-pyrazol-4-yl)pyridin-2-amine
著者McTigue, M., Deng, Y., Liu, W., Brooun, A.
登録日2011-04-08
公開日2011-05-04
最終更新日2019-05-08
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Design of Potent and Selective Inhibitors to Overcome Clinical Anaplastic Lymphoma Kinase Mutations Resistant to Crizotinib.
J.Med.Chem., 57, 2014