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1MRY
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BU of 1mry by Molmil
crystal structure of an inactive akt2 kinase domain
Descriptor: RAC-beta serine/threonine kinase
Authors:Huang, X, Begley, M, Morgenstern, K.A, Gu, Y, Rose, P, Zhao, H, Zhu, X.
Deposit date:2002-09-18
Release date:2003-09-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal structure of an inactive akt2 kinase domain
Structure, 11, 2003
6OQC
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BU of 6oqc by Molmil
Crystal structure of Mcl1 with inhibitor 9
Descriptor: (4S,7aR,9aR,10S,11E,15R)-6'-chloro-10-hydroxy-15-methyl-3',4',7a,8,9,9a,10,13,14,15-decahydro-2'H,3H,5H-spiro[1,19-(ethanediylidene)-16lambda~6~-cyclobuta[i][1,4]oxazepino[3,4-f][1,2,7]thiadiazacyclohexadecine-4,1'-naphthalene]-16,16,18(7H,17H)-trione, Induced myeloid leukemia cell differentiation protein Mcl-1
Authors:Huang, X.
Deposit date:2019-04-26
Release date:2019-05-15
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:AMG 176, a Selective MCL1 Inhibitor, Is Effective in Hematologic Cancer Models Alone and in Combination with Established Therapies.
CANCER DISCOV, 8, 2018
1MRV
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BU of 1mrv by Molmil
crystal structure of an inactive Akt2 kinase domain
Descriptor: RAC-beta serine/threonine kinase
Authors:Huang, X, Begley, M, Morgenstern, K.A, Gu, Y, Rose, P, Zhao, H, Zhu, X.
Deposit date:2002-09-18
Release date:2003-09-23
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal structure of an inactive akt2 kinase domain
Structure, 11, 2003
1EG3
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BU of 1eg3 by Molmil
STRUCTURE OF A DYSTROPHIN WW DOMAIN FRAGMENT IN COMPLEX WITH A BETA-DYSTROGLYCAN PEPTIDE
Descriptor: DYSTROPHIN
Authors:Huang, X, Poy, F, Zhang, R, Joachimiak, A, Sudol, M, Eck, M.J.
Deposit date:2000-02-11
Release date:2000-08-23
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure of a WW domain containing fragment of dystrophin in complex with beta-dystroglycan.
Nat.Struct.Biol., 7, 2000
1EG4
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BU of 1eg4 by Molmil
STRUCTURE OF A DYSTROPHIN WW DOMAIN FRAGMENT IN COMPLEX WITH A BETA-DYSTROGLYCAN PEPTIDE
Descriptor: BETA-DYSTROGLYCAN, DYSTROPHIN
Authors:Huang, X, Poy, F, Zhang, R, Joachimiak, A, Sudol, M, Eck, M.J.
Deposit date:2000-02-11
Release date:2000-08-23
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure of a WW domain containing fragment of dystrophin in complex with beta-dystroglycan.
Nat.Struct.Biol., 7, 2000
3EBU
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BU of 3ebu by Molmil
Replacement of Val3 in Human Thymidylate Synthase Affects Its Kinetic Properties and Intracellular Stability
Descriptor: 1,2-ETHANEDIOL, SULFATE ION, Thymidylate synthase
Authors:Huang, X, Gibson, L.M, Bell, B.J, Lovelace, L.L, Pena, M.M, Berger, F.G, Berger, S.H.
Deposit date:2008-08-28
Release date:2010-03-02
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Replacement of Val3 in human thymidylate synthase affects its kinetic properties and intracellular stability .
Biochemistry, 49, 2010
3EAW
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BU of 3eaw by Molmil
Replacement of Val3 in Human Thymidylate Synthase Affects Its Kinetic Properties and Intracellular Stability
Descriptor: 1,2-ETHANEDIOL, SULFATE ION, Thymidylate synthase
Authors:Huang, X, Gibson, L.M, Bell, B.J, Lovelace, L.L, Pena, M.M, Berger, F.G, Berger, S.H.
Deposit date:2008-08-26
Release date:2010-03-02
Last modified:2021-10-20
Method:X-RAY DIFFRACTION (1.86 Å)
Cite:Replacement of Val3 in human thymidylate synthase affects its kinetic properties and intracellular stability .
Biochemistry, 49, 2010
3EJL
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BU of 3ejl by Molmil
Replacement of Val3 in Human Thymidylate Synthase Affects Its Kinetic Properties and Intracellular Stability
Descriptor: 5-FLUORO-2'-DEOXYURIDINE-5'-MONOPHOSPHATE, PHOSPHATE ION, Thymidylate synthase
Authors:Huang, X, Gibson, L.M, Bell, B.J, Lovelace, L.L, Pena, M.M, Berger, F.G, Berger, S.H.
Deposit date:2008-09-18
Release date:2010-03-02
Last modified:2021-10-20
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Replacement of Val3 in human thymidylate synthase affects its kinetic properties and intracellular stability .
Biochemistry, 49, 2010
3EF9
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BU of 3ef9 by Molmil
Replacement of Val3 in Human Thymidylate Synthase Affects Its Kinetic Properties and Intracellular Stability
Descriptor: SULFATE ION, Thymidylate synthase
Authors:Huang, X, Gibson, L.M, Bell, B.J, Lovelace, L.L, Pena, M.M, Berger, F.G, Berger, S.H.
Deposit date:2008-09-08
Release date:2010-03-02
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Replacement of Val3 in human thymidylate synthase affects its kinetic properties and intracellular stability .
Biochemistry, 49, 2010
3ED7
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BU of 3ed7 by Molmil
Replacement of Val3 in Human Thymidylate Synthase Affects Its Kinetic Properties and Intracellular Stability
Descriptor: SULFATE ION, Thymidylate synthase
Authors:Huang, X, Gibson, L.M, Bell, B.J, Lovelace, L.L, Pena, M.M, Berger, F.G, Berger, S.H.
Deposit date:2008-09-02
Release date:2010-03-02
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.56 Å)
Cite:Replacement of Val3 in human thymidylate synthase affects its kinetic properties and intracellular stability .
Biochemistry, 49, 2010
3EDW
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BU of 3edw by Molmil
Replacement of Val3 in Human Thymidylate Synthase Affects Its Kinetic Properties and Intracellular Stability
Descriptor: SULFATE ION, Thymidylate synthase
Authors:Huang, X, Gibson, L.M, Bell, B.J, Lovelace, L.L, Pena, M.M, Berger, F.G, Berger, S.H.
Deposit date:2008-09-03
Release date:2010-03-02
Last modified:2021-10-20
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Replacement of Val3 in human thymidylate synthase affects its kinetic properties and intracellular stability .
Biochemistry, 49, 2010
6IP1
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BU of 6ip1 by Molmil
alpha-SNAP-SNARE subcomplex in the whole 20S complex
Descriptor: Alpha-soluble NSF attachment protein, Synaptosomal-associated protein 25, Syntaxin-1A, ...
Authors:Huang, X, Sun, S, Wang, X, Fan, F, Zhou, Q, Sui, S.F.
Deposit date:2018-11-01
Release date:2019-04-24
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Mechanistic insights into the SNARE complex disassembly.
Sci Adv, 5, 2019
6IP2
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BU of 6ip2 by Molmil
NSF-D1D2 part in the whole 20S complex
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Vesicle-fusing ATPase
Authors:Huang, X, Sun, S, Wang, X, Fan, F, Zhou, Q, Sui, S.F.
Deposit date:2018-11-01
Release date:2019-04-24
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Mechanistic insights into the SNARE complex disassembly.
Sci Adv, 5, 2019
4HGS
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BU of 4hgs by Molmil
Crystal structure of ck1gs with compound 13
Descriptor: 2-{2-[(3,4-difluorophenoxy)methyl]-5-methoxypyridin-4-yl}-1,5,6,7-tetrahydro-4H-pyrrolo[3,2-c]pyridin-4-one, Casein kinase I isoform gamma-3
Authors:Huang, X.
Deposit date:2012-10-08
Release date:2012-11-21
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal structure of ck1gs with compound 13
Acs Med.Chem.Lett
2JHB
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BU of 2jhb by Molmil
CORE BINDING FACTOR BETA
Descriptor: PROTEIN (CORE BINDING FACTOR BETA)
Authors:Huang, X, Peng, J, Speck, N.A, Bushweller, J.H.
Deposit date:1999-03-17
Release date:1999-07-05
Last modified:2023-12-27
Method:SOLUTION NMR
Cite:Solution structure of core binding factor beta and map of the CBF alpha binding site.
Nat.Struct.Biol., 6, 1999
3GH0
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BU of 3gh0 by Molmil
Replacement of Val3 in Human Thymidylate Synthase Affects Its Kinetic Properties and Intracellular Stability
Descriptor: SULFATE ION, Thymidylate synthase
Authors:Huang, X, Gibson, L.M, Bell, B.J, Lovelace, L.L, Lebioda, L.
Deposit date:2009-03-02
Release date:2010-03-02
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.56 Å)
Cite:Replacement of Val3 in human thymidylate synthase affects its kinetic properties and intracellular stability .
Biochemistry, 49, 2010
3GH2
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BU of 3gh2 by Molmil
Replacement of Val3 in Human Thymidylate Synthase Affects Its Kinetic Properties and Intracellular Stability
Descriptor: SULFATE ION, Thymidylate synthase
Authors:Huang, X, Gibson, L.M, Bell, B.J, Lovelace, L.L, Lebioda, L.
Deposit date:2009-03-02
Release date:2010-03-02
Last modified:2021-10-20
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Replacement of Val3 in human thymidylate synthase affects its kinetic properties and intracellular stability .
Biochemistry, 49, 2010
3GG5
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BU of 3gg5 by Molmil
Replacement of Val3 in Human Thymidylate Synthase Affects Its Kinetic Properties and Intracellular Stability
Descriptor: PHOSPHATE ION, SULFATE ION, Thymidylate synthase
Authors:Huang, X, Gibson, L.M, Bell, B.J, Lovelace, L.L, Lebioda, L.
Deposit date:2009-02-27
Release date:2010-03-02
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.77 Å)
Cite:Replacement of Val3 in human thymidylate synthase affects its kinetic properties and intracellular stability .
Biochemistry, 49, 2010
3O89
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BU of 3o89 by Molmil
Crystal Structure of Sperm Whale Myoglobin G65T
Descriptor: Myoglobin, PROTOPORPHYRIN IX CONTAINING FE, SULFATE ION
Authors:Huang, X, Lovelace, L, Lebioda, L.
Deposit date:2010-08-02
Release date:2011-12-07
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.1 Å)
Cite:Investigations of Structural Factors that Influence the Mechanism of Halophenol Dehalogenation using 'Peroxidase-Like' Myoglobin mutants and 'Myoglobin-Like' Amphitrite ornata Dehaloperoxidase Mutants
TO BE PUBLISHED
2R8U
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BU of 2r8u by Molmil
Structure of fragment of human end-binding protein 1 (EB1) containing the N-terminal domain at 1.35 A resolution
Descriptor: MOLYBDATE ION, Microtubule-associated protein RP/EB family member 1
Authors:Huang, X, Lovelace, L.L, Smith, D, Lebioda, L.
Deposit date:2007-09-11
Release date:2008-09-23
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.35 Å)
Cite:Structure of fragment of human end-binding protein 1 (EB1) containing the N-terminal domain at 1.35 A resolution
To be Published
8IGO
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BU of 8igo by Molmil
Crystal structure of apo SARS-CoV-2 main protease
Descriptor: 3C-like proteinase nsp5
Authors:Huang, X, Zhou, B, Xu, J, Yang, Z, Zhong, N, Xiong, X.
Deposit date:2023-02-21
Release date:2023-04-05
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2 Å)
Cite:Inhibition mechanism and antiviral activity of an alpha-ketoamide based SARS-CoV-2 main protease inhibitor
To Be Published
8IGN
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BU of 8ign by Molmil
Crystal structure of SARS-CoV-2 main protease in complex with RAY1216
Descriptor: (3~{S},3~{a}~{S},6~{a}~{R})-2-[(2~{S})-2-cyclohexyl-2-[2,2,2-tris(fluoranyl)ethanoylamino]ethanoyl]-~{N}-[(2~{S})-4-(cyclopentylamino)-3,4-bis(oxidanylidene)-1-[(3~{S})-2-oxidanylidenepyrrolidin-3-yl]butan-2-yl]-3,3~{a},4,5,6,6~{a}-hexahydro-1~{H}-cyclopenta[c]pyrrole-3-carboxamide, 3C-like proteinase nsp5
Authors:Huang, X, Zhou, B, Xu, J, Yang, Z, Zhong, N, Xiong, X.
Deposit date:2023-02-21
Release date:2023-04-05
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.02 Å)
Cite:Inhibition mechanism and antiviral activity of an alpha-ketoamide based SARS-CoV-2 main protease inhibitor
To Be Published
8I3D
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BU of 8i3d by Molmil
Cryo-EM structure of abscisic acid transporter AtABCG25
Descriptor: ABC transporter G family member 25
Authors:Huang, X, Zhang, X, Zhang, P.
Deposit date:2023-01-17
Release date:2023-09-13
Last modified:2023-11-01
Method:ELECTRON MICROSCOPY (2.81 Å)
Cite:Cryo-EM structure and molecular mechanism of abscisic acid transporter ABCG25.
Nat.Plants, 9, 2023
8I3A
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BU of 8i3a by Molmil
Cryo-EM structure of abscisic acid transporter AtABCG25 in outward conformation
Descriptor: ABC transporter G family member 25, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION
Authors:Huang, X, Zhang, X, Zhang, P.
Deposit date:2023-01-16
Release date:2023-09-13
Last modified:2023-11-01
Method:ELECTRON MICROSCOPY (3.04 Å)
Cite:Cryo-EM structure and molecular mechanism of abscisic acid transporter ABCG25.
Nat.Plants, 9, 2023
8I3B
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BU of 8i3b by Molmil
Cryo-EM structure of abscisic acid transporter AtABCG25 in nanodisc
Descriptor: ABC transporter G family member 25, ADENOSINE-5'-TRIPHOSPHATE
Authors:Huang, X, Zhang, X, Zhang, P.
Deposit date:2023-01-16
Release date:2023-09-13
Last modified:2023-11-01
Method:ELECTRON MICROSCOPY (3.08 Å)
Cite:Cryo-EM structure and molecular mechanism of abscisic acid transporter ABCG25.
Nat.Plants, 9, 2023

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PDB entries from 2024-03-27

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