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4V2A
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HUMAN UNC5A ECTODOMAIN
Descriptor:NETRIN RECEPTOR UNC5A, N-ACETYL-D-GLUCOSAMINE
Authors:Seiradake, E., del Toro, D., Nagel, D., Cop, F., Haertl, R., Ruff, T., Seyit-Bremer, G., Harlos, K., Border, E.C., Acker-Palmer, A., Jones, E.Y., Klein, R.
Deposit date:2014-10-08
Release date:2014-11-05
Last modified:2015-07-22
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Flrt Structure: Balancing Repulsion and Cell Adhesion in Cortical and Vascular Development
Neuron, 84, 2014
4V2B
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RAT UNC5D IG DOMAIN 1
Descriptor:PROTEIN UNC5D
Authors:Seiradake, E., del Toro, D., Nagel, D., Cop, F., Haertl, R., Ruff, T., Seyit-Bremer, G., Harlos, K., Border, E.C., Acker-Palmer, A., Jones, E.Y., Klein, R.
Deposit date:2014-10-08
Release date:2014-11-05
Last modified:2015-07-22
Method:X-RAY DIFFRACTION (2 Å)
Cite:Flrt Structure: Balancing Repulsion and Cell Adhesion in Cortical and Vascular Development
Neuron, 84, 2014
4V2C
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MOUSE FLRT2 LRR DOMAIN IN COMPLEX WITH RAT UNC5D IG1 DOMAIN
Descriptor:FIBRONECTIN LEUCINE RICH TRANSMEMBRANE PROTEIN 2, PROTEIN UNC5D
Authors:Seiradake, E., del Toro, D., Nagel, D., Cop, F., Haertl, R., Ruff, T., Seyit-Bremer, G., Harlos, K., Border, E.C., Acker-Palmer, A., Jones, E.Y., Klein, R.
Deposit date:2014-10-08
Release date:2014-11-05
Last modified:2015-07-22
Method:X-RAY DIFFRACTION (4 Å)
Cite:Flrt Structure: Balancing Repulsion and Cell Adhesion in Cortical and Vascular Development
Neuron, 84, 2014
4V2D
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FLRT2 LRR DOMAIN
Descriptor:FIBRONECTIN LEUCINE RICH TRANSMEMBRANE PROTEIN 2
Authors:Seiradake, E., del Toro, D., Nagel, D., Cop, F., Haertl, R., Ruff, T., Seyit-Bremer, G., Harlos, K., Border, E.C., Acker-Palmer, A., Jones, E.Y., Klein, R.
Deposit date:2014-10-08
Release date:2014-11-05
Last modified:2015-07-22
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Flrt Structure: Balancing Repulsion and Cell Adhesion in Cortical and Vascular Development
Neuron, 84, 2014
4V2E
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FLRT3 LRR DOMAIN
Descriptor:FIBRONECTIN LEUCINE RICH TRANSMEMBRANE PROTEIN 3
Authors:Seiradake, E., del Toro, D., Nagel, D., Cop, F., Haertl, R., Ruff, T., Seyit-Bremer, G., Harlos, K., Border, E.C., Acker-Palmer, A., Jones, E.Y., Klein, R.
Deposit date:2014-10-08
Release date:2014-11-05
Last modified:2015-08-12
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Flrt Structure: Balancing Repulsion and Cell Adhesion in Cortical and Vascular Development.
Neuron, 84, 2014
4WJX
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CRYSTAL STRUCTURE OF HUMAN CHITOTRIOSIDASE-1 CATALYTIC DOMAIN AT 1.0 A RESOLUTION
Descriptor:Chitotriosidase-1, L(+)-TARTARIC ACID
Authors:Fadel, F., Zhao, Y., Cachau, R., Cousido-Siah, A., Ruiz, F.X., Harlos, K., Howard, E., Mitschler, A., Podjarny, A.
Deposit date:2014-10-01
Release date:2015-07-08
Last modified:2015-07-22
Method:X-RAY DIFFRACTION (1 Å)
Cite:New insights into the enzymatic mechanism of human chitotriosidase (CHIT1) catalytic domain by atomic resolution X-ray diffraction and hybrid QM/MM
Acta Crystallogr.,Sect.D, 71, 2015
4WK9
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CRYSTAL STRUCTURE OF HUMAN CHITOTRIOSIDASE-1 CATALYTIC DOMAIN IN COMPLEX WITH CHITOBIOSE (0.3MM) AT 1.10 A RESOLUTION
Descriptor:Chitotriosidase-1, DI(N-ACETYL-D-GLUCOSAMINE)
Authors:Fadel, F., Zhao, Y., Cachau, R., Cousido-Siah, A., Ruiz, F.X., Harlos, K., Howard, E., Mitschler, A., Podjarny, A.
Deposit date:2014-10-02
Release date:2015-07-08
Last modified:2018-02-28
Method:X-RAY DIFFRACTION (1.102 Å)
Cite:New insights into the enzymatic mechanism of human chitotriosidase (CHIT1) catalytic domain by atomic resolution X-ray diffraction and hybrid QM/MM.
Acta Crystallogr.,Sect.D, 71, 2015
4WKA
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CRYSTAL STRUCTURE OF HUMAN CHITOTRIOSIDASE-1 CATALYTIC DOMAIN AT 0.95 A RESOLUTION
Descriptor:Chitotriosidase-1, L(+)-TARTARIC ACID
Authors:Fadel, F., Zhao, Y., Cachau, R., Cousido-Siah, A., Ruiz, F.X., Harlos, K., Howard, E., Mitschler, A., Podjarny, A.
Deposit date:2014-10-02
Release date:2015-07-08
Last modified:2015-07-22
Method:X-RAY DIFFRACTION (0.95 Å)
Cite:New insights into the enzymatic mechanism of human chitotriosidase (CHIT1) catalytic domain by atomic resolution X-ray diffraction and hybrid QM/MM.
Acta Crystallogr.,Sect.D, 71, 2015
4WKF
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CRYSTAL STRUCTURE OF HUMAN CHITOTRIOSIDASE-1 CATALYTIC DOMAIN IN COMPLEX WITH CHITOBIOSE (2.5MM) AT 1.10 A RESOLUTION
Descriptor:Chitotriosidase-1, DI(N-ACETYL-D-GLUCOSAMINE)
Authors:Fadel, F., Zhao, Y., Cachau, R., Cousido-Siah, A., Ruiz, F.X., Harlos, K., Howard, E., Mitschler, A., Podjarny, A.
Deposit date:2014-10-02
Release date:2015-07-08
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (1.101 Å)
Cite:New insights into the enzymatic mechanism of human chitotriosidase (CHIT1) catalytic domain by atomic resolution X-ray diffraction and hybrid QM/MM.
Acta Crystallogr.,Sect.D, 71, 2015
4WKH
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CRYSTAL STRUCTURE OF HUMAN CHITOTRIOSIDASE-1 CATALYTIC DOMAIN IN COMPLEX WITH CHITOBIOSE (1MM) AT 1.05 A RESOLUTION
Descriptor:Chitotriosidase-1, DI(N-ACETYL-D-GLUCOSAMINE)
Authors:Fadel, F., Zhao, Y., Cachau, R., Cousido-Siah, A., Ruiz, F.X., Harlos, K., Howard, E., Mitschler, A., Podjarny, A.
Deposit date:2014-10-02
Release date:2015-07-08
Last modified:2015-07-22
Method:X-RAY DIFFRACTION (1.05 Å)
Cite:New insights into the enzymatic mechanism of human chitotriosidase (CHIT1) catalytic domain by atomic resolution X-ray diffraction and hybrid QM/MM.
Acta Crystallogr.,Sect.D, 71, 2015
4Z7I
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CRYSTAL STRUCTURE OF INSULIN REGULATED AMINOPEPTIDASE IN COMPLEX WITH LIGAND
Descriptor:Leucyl-cystinyl aminopeptidase, DG025 transition-state analogue enzyme inhibitor, ZINC ION, ...
Authors:Mpakali, A., Saridakis, E., Harlos, K., Zhao, Y., Stratikos, E.
Deposit date:2015-04-07
Release date:2015-08-26
Last modified:2015-09-16
Method:X-RAY DIFFRACTION (3.31 Å)
Cite:Crystal Structure of Insulin-Regulated Aminopeptidase with Bound Substrate Analogue Provides Insight on Antigenic Epitope Precursor Recognition and Processing.
J Immunol., 195, 2015
5AFB
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CRYSTAL STRUCTURE OF THE LATROPHILIN3 LECTIN AND OLFACTOMEDIN DOMAINS
Descriptor:LATROPHILIN-3, N-ACETYL-D-GLUCOSAMINE, SODIUM ION, ...
Authors:Jackson, V.A., del Toro, D., Carrasquero, M., Roversi, P., Harlos, K., Klein, R., Seiradake, E.
Deposit date:2015-01-21
Release date:2015-03-18
Last modified:2016-03-09
Method:X-RAY DIFFRACTION (2.16 Å)
Cite:Structural Basis of Latrophilin-Flrt Interaction.
Structure, 23, 2015
5BPB
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CRYSTAL STRUCTURE OF THE CYSTEINE-RICH DOMAIN OF HUMAN FRIZZLED 4 - CRYSTAL FORM I
Descriptor:Frizzled-4, N-ACETYL-D-GLUCOSAMINE
Authors:Chang, T.-H., Hsieh, F.-L., Harlos, K., Jones, E.Y.
Deposit date:2015-05-27
Release date:2015-07-01
Last modified:2017-09-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structure and functional properties of Norrin mimic Wnt for signalling with Frizzled4, Lrp5/6, and proteoglycan.
Elife, 4, 2015
5BPQ
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CRYSTAL STRUCTURE OF THE CYSTEINE-RICH DOMAIN OF HUMAN FRIZZLED 4 - CRYSTAL FORM II
Descriptor:Frizzled-4, N-ACETYL-D-GLUCOSAMINE, CHLORIDE ION
Authors:Chang, T.-H., Hsieh, F.-L., Harlos, K., Jones, E.Y.
Deposit date:2015-05-28
Release date:2015-07-01
Last modified:2017-09-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structure and functional properties of Norrin mimic Wnt for signalling with Frizzled4, Lrp5/6, and proteoglycan.
Elife, 4, 2015
5BPU
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CRYSTAL STRUCTURE OF NORRIN, A WNT SIGNALLING ACTIVATOR, CRYSTAL FORM I
Descriptor:Norrin, (GGL)EEEEEE, (GGL)EEE
Authors:Chang, T.-H., Hsieh, F.-L., Harlos, K., Jones, E.Y.
Deposit date:2015-05-28
Release date:2015-07-01
Last modified:2019-07-10
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structure and functional properties of Norrin mimic Wnt for signalling with Frizzled4, Lrp5/6, and proteoglycan.
Elife, 4, 2015
5BQ8
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CRYSTAL STRUCTURE OF NORRIN, A WNT SIGNALLING ACTIVATOR, CRYSTAL FORM II
Descriptor:Norrin, CHLORIDE ION, DI(HYDROXYETHYL)ETHER
Authors:Chang, T.-H., Hsieh, F.-L., Harlos, K., Jones, E.Y.
Deposit date:2015-05-28
Release date:2015-07-01
Last modified:2017-09-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure and functional properties of Norrin mimic Wnt for signalling with Frizzled4, Lrp5/6, and proteoglycan.
Elife, 4, 2015
5BQB
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CRYSTAL STRUCTURE OF NORRIN, A WNT SIGNALLING ACTIVATOR, CRYSTAL FORM III
Descriptor:Norrin, CITRIC ACID, CHLORIDE ION
Authors:Chang, T.-H., Hsieh, F.-L., Harlos, K., Jones, E.Y.
Deposit date:2015-05-28
Release date:2015-07-01
Last modified:2017-09-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structure and functional properties of Norrin mimic Wnt for signalling with Frizzled4, Lrp5/6, and proteoglycan.
Elife, 4, 2015
5BQC
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CRYSTAL STRUCTURE OF NORRIN IN COMPLEX WITH THE CYSTEINE-RICH DOMAIN OF FRIZZLED 4 AND SUCROSE OCTASULFATE
Descriptor:Frizzled-4, Norrin, N-ACETYL-D-GLUCOSAMINE, ...
Authors:Chang, T.-H., Hsieh, F.-L., Zebisch, M., Harlos, K., Jones, E.Y.
Deposit date:2015-05-28
Release date:2015-07-01
Last modified:2017-09-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structure and functional properties of Norrin mimic Wnt for signalling with Frizzled4, Lrp5/6, and proteoglycan.
Elife, 4, 2015
5BQE
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CRYSTAL STRUCTURE OF NORRIN IN COMPLEX WITH THE CYSTEINE-RICH DOMAIN OF FRIZZLED 4 -METHYLATED FORM
Descriptor:Norrin, Frizzled-4, 2-(2-METHOXYETHOXY)ETHANOL, ...
Authors:Chang, T.-H., Hsieh, F.-L., Harlos, K., Jones, E.Y.
Deposit date:2015-05-28
Release date:2015-07-01
Last modified:2017-09-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structure and functional properties of Norrin mimic Wnt for signalling with Frizzled4, Lrp5/6, and proteoglycan.
Elife, 4, 2015
5C97
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INSULIN REGULATED AMINOPEPTIDASE
Descriptor:Leucyl-cystinyl aminopeptidase, ZINC ION, N-ACETYL-D-GLUCOSAMINE
Authors:Mpakali, A., Saridakis, E., Harlos, K., Zhao, Y., Stratikos, E.
Deposit date:2015-06-26
Release date:2015-08-26
Last modified:2015-09-16
Method:X-RAY DIFFRACTION (3.37 Å)
Cite:Crystal Structure of Insulin-Regulated Aminopeptidase with Bound Substrate Analogue Provides Insight on Antigenic Epitope Precursor Recognition and Processing.
J Immunol., 195, 2015
5FMV
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CRYSTAL STRUCTURE OF HUMAN CD45 EXTRACELLULAR REGION, DOMAINS D1-D4
Descriptor:RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE C, N-ACETYL-D-GLUCOSAMINE, SULFATE ION
Authors:Chang, V.T., Fernandes, R.A., Ganzinger, K.A., Lee, S.F., Siebold, C., McColl, J., Jonsson, P., Palayret, M., Harlos, K., Coles, C.H., Jones, E.Y., Lui, Y., Huang, E., Gilbert, R.J.C., Klenerman, D., Aricescu, A.R., Davis, S.J.
Deposit date:2015-11-09
Release date:2016-03-23
Last modified:2017-09-13
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Initiation of T Cell Signaling by Cd45 Segregation at 'Close Contacts'.
Nat.Immunol., 17, 2016
5FN6
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CRYSTAL STRUCTURE OF HUMAN CD45 EXTRACELLULAR REGION, DOMAINS D1-D3
Descriptor:RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE C, N-ACETYL-D-GLUCOSAMINE
Authors:Chang, V.T., Fernandes, R.A., Ganzinger, K.A., Lee, S.F., Siebold, C., McColl, J., Jonsson, P., Palayret, M., Harlos, K., Coles, C.H., Jones, E.Y., Lui, Y., Huang, E., Gilbert, R.J.C., Klenerman, D., Aricescu, A.R., Davis, S.J.
Deposit date:2015-11-10
Release date:2016-03-23
Last modified:2019-04-03
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Initiation of T Cell Signaling by Cd45 Segregation at 'Close Contacts'.
Nat.Immunol., 17, 2016
5FN7
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CRYSTAL STRUCTURE OF HUMAN CD45 EXTRACELLULAR REGION, DOMAINS D1-D2
Descriptor:RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE C, N-ACETYL-D-GLUCOSAMINE, MERCURY (II) ION
Authors:Chang, V.T., Fernandes, R.A., Ganzinger, K.A., Lee, S.F., Siebold, C., McColl, J., Jonsson, P., Palayret, M., Harlos, K., Coles, C.H., Jones, E.Y., Lui, Y., Huang, E., Gilbert, R.J.C., Klenerman, D., Aricescu, A.R., Davis, S.J.
Deposit date:2015-11-10
Release date:2016-03-23
Last modified:2019-04-03
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Initiation of T Cell Signaling by Cd45 Segregation at 'Close Contacts'.
Nat.Immunol., 17, 2016
5FN8
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CRYSTAL STRUCTURE OF RAT CD45 EXTRACELLULAR REGION, DOMAINS D3-D4
Descriptor:RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE C, N-ACETYL-D-GLUCOSAMINE, CITRATE ANION
Authors:Chang, V.T., Fernandes, R.A., Ganzinger, K.A., Lee, S.F., Siebold, C., McColl, J., Jonsson, P., Palayret, M., Harlos, K., Coles, C.H., Jones, E.Y., Lui, Y., Huang, E., Gilbert, R.J.C., Klenerman, D., Aricescu, A.R., Davis, S.J.
Deposit date:2015-11-11
Release date:2016-03-23
Last modified:2016-05-04
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Initiation of T Cell Signaling by Cd45 Segregation at 'Close Contacts'.
Nat.Immunol., 17, 2016
5FXU
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CRYSTAL STRUCTURE OF PUUMALA VIRUS GN GLYCOPROTEIN ECTODOMAIN
Descriptor:ENVELOPE POLYPROTEIN, N-ACETYL-D-GLUCOSAMINE, BETA-D-MANNOSE, ...
Authors:Li, S., Rissanen, I., Zeltina, A., Hepojoki, J., Raghwani, J., Harlos, K., Pybus, O.G., Huiskonen, J.T., Bowden, T.A.
Deposit date:2016-03-02
Release date:2016-05-18
Last modified:2018-02-28
Method:X-RAY DIFFRACTION (2.28 Å)
Cite:A Molecular-Level Account of the Antigenic Hantaviral Surface.
Cell Rep., 15, 2016