225D
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8CT8
| Crystal structure of Drosophila melanogaster PRL/CBS-pair domain complex | Descriptor: | IODIDE ION, PRL-1 phosphatase, Unextended protein | Authors: | Fakih, R, Goldstein, R.H, Kozlov, G, Gehring, K. | Deposit date: | 2022-05-13 | Release date: | 2023-03-01 | Last modified: | 2023-04-05 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Burst kinetics and CNNM binding are evolutionarily conserved properties of phosphatases of regenerating liver. J.Biol.Chem., 299, 2023
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7SOW
| LaM domain of human LARP1 in complex with UUUUUU | Descriptor: | 1,2-ETHANEDIOL, Isoform 2 of La-related protein 1, RNA (5'-R(P*UP*UP*UP*UP*UP*U)-3') | Authors: | Kozlov, G, Gehring, K. | Deposit date: | 2021-11-01 | Release date: | 2022-11-09 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.3 Å) | Cite: | Structural basis of 3'-end RNA recognition by LARP1 To Be Published
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7US1
| Structure of parkin (R0RB) bound to two phospho-ubiquitin molecules | Descriptor: | 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, E3 ubiquitin-protein ligase parkin, ... | Authors: | Fakih, R, Sauve, V, Gehring, K. | Deposit date: | 2022-04-22 | Release date: | 2022-06-22 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.484 Å) | Cite: | Structure of the second phosphoubiquitin-binding site in parkin. J.Biol.Chem., 298, 2022
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8GK6
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4K7D
| Crystal Structure of Parkin C-terminal RING domains | Descriptor: | CHLORIDE ION, E3 ubiquitin-protein ligase parkin, MALONATE ION, ... | Authors: | Sauve, V, Trempe, J.-F, Menade, M, Gehring, K. | Deposit date: | 2013-04-17 | Release date: | 2013-05-15 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structure of parkin reveals mechanisms for ubiquitin ligase activation. Science, 340, 2013
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4K95
| Crystal Structure of Parkin | Descriptor: | E3 ubiquitin-protein ligase parkin, ZINC ION | Authors: | Seirafi, M, Menade, M, Sauve, V, Kozlov, G, Trempe, J.-F, Nagar, B, Gehring, K. | Deposit date: | 2013-04-19 | Release date: | 2013-05-15 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (6.499 Å) | Cite: | Structure of parkin reveals mechanisms for ubiquitin ligase activation. Science, 340, 2013
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6B3Y
| Crystal structure of the PH-like domain from DENND3 | Descriptor: | DENN domain-containing protein 3 | Authors: | Kozlov, G, Xu, J, Menade, M, Beaugrand, M, Pan, T, McPherson, P.S, Gehring, K. | Deposit date: | 2017-09-25 | Release date: | 2018-01-24 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (1.852 Å) | Cite: | A PH-like domain of the Rab12 guanine nucleotide exchange factor DENND3 binds actin and is required for autophagy. J. Biol. Chem., 293, 2018
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7MSU
| Crystal structure of an archaeal CNNM, MtCorB, CBS-pair domain in complex with Mg2+-ATP | Descriptor: | 1,2-ETHANEDIOL, ADENOSINE-5'-TRIPHOSPHATE, Hemolysin, ... | Authors: | Chen, Y.S, Gehring, K. | Deposit date: | 2021-05-12 | Release date: | 2021-06-16 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.07 Å) | Cite: | Crystal structure of an archaeal CorB magnesium transporter. Nat Commun, 12, 2021
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6MN6
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5KDG
| Crystal Structure of Salmonella Typhimurium Effector GtgE | Descriptor: | GLYCEROL, Gifsy-2 prophage protein, SULFATE ION | Authors: | Kozlov, G, Xu, C, Wong, K, Gehring, K, Cygler, M, Montreal-Kingston Bacterial Structural Genomics Initiative (BSGI) | Deposit date: | 2016-06-08 | Release date: | 2016-11-16 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.73 Å) | Cite: | Crystal Structure of the Salmonella Typhimurium Effector GtgE. PLoS ONE, 11, 2016
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4Z2Z
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4ZYN
| Crystal Structure of Parkin E3 ubiquitin ligase (linker deletion; delta 86-130) | Descriptor: | E3 ubiquitin-protein ligase parkin, SULFATE ION, ZINC ION | Authors: | Lilov, A, Sauve, V, Trempe, J.F, Rodionov, D, Wang, J, Gehring, K. | Deposit date: | 2015-05-21 | Release date: | 2015-08-19 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.54 Å) | Cite: | A Ubl/ubiquitin switch in the activation of Parkin. Embo J., 34, 2015
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5K35
| Structure of the Legionella effector, AnkB, in complex with human Skp1 | Descriptor: | Ankyrin-repeat protein B, S-phase kinase-associated protein 1 | Authors: | Wong, K, Kozlov, G, Gehring, K, Montreal-Kingston Bacterial Structural Genomics Initiative (BSGI) | Deposit date: | 2016-05-19 | Release date: | 2017-01-25 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (2.85 Å) | Cite: | Structural Mimicry by a Bacterial F Box Effector Hijacks the Host Ubiquitin-Proteasome System. Structure, 25, 2017
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5K34
| Structure of the ankyrin domain of AnkB from Legionella Pneumophila | Descriptor: | Ankyrin-repeat protein B, GLYCEROL, SULFATE ION | Authors: | Wong, K, Kozlov, G, Gehring, K, Montreal-Kingston Bacterial Structural Genomics Initiative (BSGI) | Deposit date: | 2016-05-19 | Release date: | 2017-01-25 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (1.15 Å) | Cite: | Structural Mimicry by a Bacterial F Box Effector Hijacks the Host Ubiquitin-Proteasome System. Structure, 25, 2017
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5KES
| Solution structure of the yeast Ddi1 HDD domain | Descriptor: | DNA damage-inducible protein 1 | Authors: | Trempe, J.-F, Ratcliffe, C, Veverka, V, Saskova, K, Gehring, K. | Deposit date: | 2016-06-10 | Release date: | 2016-10-05 | Last modified: | 2023-06-14 | Method: | SOLUTION NMR | Cite: | Structural studies of the yeast DNA damage-inducible protein Ddi1 reveal domain architecture of this eukaryotic protein family. Sci Rep, 6, 2016
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8F6D
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8EY7
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8EY6
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8EY8
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8G91
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8G90
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6WUS
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6WUR
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6PIK
| Tetrameric cryo-EM ArnA | Descriptor: | Bifunctional polymyxin resistance protein ArnA, UDP-4-amino-4-deoxy-L-arabinose formyltransferase | Authors: | Yang, M, Gehring, K. | Deposit date: | 2019-06-26 | Release date: | 2019-07-31 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (7.8 Å) | Cite: | Cryo-electron microscopy structures of ArnA, a key enzyme for polymyxin resistance, revealed unexpected oligomerizations and domain movements. J.Struct.Biol., 208, 2019
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