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3F5C
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BU of 3f5c by Molmil
Structure of Dax-1:LRH-1 complex
Descriptor: Nuclear receptor subfamily 0 group B member 1, Nuclear receptor subfamily 5 group A member 2
Authors:Fletterick, R.J, Sablin, E.P.
Deposit date:2008-11-03
Release date:2008-12-23
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (3 Å)
Cite:The structure of corepressor Dax-1 bound to its target nuclear receptor LRH-1.
Proc.Natl.Acad.Sci.USA, 105, 2008
1ANE
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BU of 1ane by Molmil
ANIONIC TRYPSIN WILD TYPE
Descriptor: ANIONIC TRYPSIN, BENZAMIDINE
Authors:Fletterick, R.J, Mcgrath, M.E.
Deposit date:1994-12-21
Release date:1997-04-01
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structure of an engineered, metal-actuated switch in trypsin.
Biochemistry, 32, 1993
1ANC
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BU of 1anc by Molmil
ANIONIC TRYPSIN MUTANT WITH SER 214 REPLACED BY LYS
Descriptor: ANIONIC TRYPSIN, BENZAMIDINE, CALCIUM ION
Authors:Fletterick, R.J, Mcgrath, M.E.
Deposit date:1994-12-21
Release date:1997-04-01
Last modified:2021-11-03
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Perturbing the polar environment of Asp102 in trypsin: consequences of replacing conserved Ser214.
Biochemistry, 31, 1992
1ANB
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BU of 1anb by Molmil
ANIONIC TRYPSIN MUTANT WITH SER 214 REPLACED BY GLU
Descriptor: ANIONIC TRYPSIN, BENZAMIDINE, CALCIUM ION
Authors:Fletterick, R.J, Mcgrath, M.E.
Deposit date:1994-12-21
Release date:1997-04-01
Last modified:2021-11-03
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Perturbing the polar environment of Asp102 in trypsin: consequences of replacing conserved Ser214.
Biochemistry, 31, 1992
1AND
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BU of 1and by Molmil
ANIONIC TRYPSIN MUTANT WITH ARG 96 REPLACED BY HIS
Descriptor: ANIONIC TRYPSIN, BENZAMIDINE, COPPER (II) ION
Authors:Fletterick, R.J, Mcgrath, M.E.
Deposit date:1994-12-21
Release date:1997-04-01
Last modified:2021-11-03
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structure of an engineered, metal-actuated switch in trypsin.
Biochemistry, 32, 1993
2AIM
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BU of 2aim by Molmil
CRUZAIN INHIBITED WITH BENZOYL-ARGININE-ALANINE-FLUOROMETHYLKETONE
Descriptor: BENZOYL-ARGININE-ALANINE-FLUORO-METHYL KETONE, CRUZAIN
Authors:Gillmor, S.A, Fletterick, R.J.
Deposit date:1997-04-21
Release date:1997-10-22
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural determinants of specificity in the cysteine protease cruzain.
Protein Sci., 6, 1997
1CR9
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BU of 1cr9 by Molmil
CRYSTAL STRUCTURE OF THE ANTI-PRION FAB 3F4
Descriptor: FAB ANTIBODY HEAVY CHAIN, FAB ANTIBODY LIGHT CHAIN
Authors:Kanyo, Z.F, Pan, K.M, Williamson, R.A, Burton, D.R, Prusiner, S.B, Fletterick, R.J, Cohen, F.E.
Deposit date:1999-08-14
Release date:2000-04-17
Last modified:2018-04-04
Method:X-RAY DIFFRACTION (2 Å)
Cite:Antibody binding defines a structure for an epitope that participates in the PrPC-->PrPSc conformational change.
J.Mol.Biol., 293, 1999
1CU4
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BU of 1cu4 by Molmil
CRYSTAL STRUCTURE OF THE ANTI-PRION FAB 3F4 IN COMPLEX WITH ITS PEPTIDE EPITOPE
Descriptor: FAB HEAVY CHAIN, FAB LIGHT CHAIN, RECOGNITION PEPTIDE
Authors:Kanyo, Z.F, Pan, K.M, Williamson, R.A, Burton, D.R, Prusiner, S.B, Fletterick, R.J, Cohen, F.E.
Deposit date:1999-08-20
Release date:2000-04-17
Last modified:2018-04-04
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Antibody binding defines a structure for an epitope that participates in the PrPC-->PrPSc conformational change.
J.Mol.Biol., 293, 1999
6DDA
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BU of 6dda by Molmil
Nurr1 Covalently Modified by a Dopamine Metabolite
Descriptor: 5-hydroxy-1,2-dihydro-6H-indol-6-one, BROMIDE ION, Nuclear receptor subfamily 4 group A member 2, ...
Authors:Bruning, J.M, Wang, Y, Otrabella, F, Boxue, T, Liu, H, Bhattacharya, P, Guo, S, Holton, J.M, Fletterick, R.J, Jacobson, M.P, England, P.M.
Deposit date:2018-05-09
Release date:2019-03-20
Last modified:2019-11-06
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Covalent Modification and Regulation of the Nuclear Receptor Nurr1 by a Dopamine Metabolite.
Cell Chem Biol, 26, 2019
1YGP
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BU of 1ygp by Molmil
PHOSPHORYLATED FORM OF YEAST GLYCOGEN PHOSPHORYLASE WITH PHOSPHATE BOUND IN THE ACTIVE SITE.
Descriptor: PHOSPHATE ION, PYRIDOXAL-5'-PHOSPHATE, YEAST GLYCOGEN PHOSPHORYLASE
Authors:Lin, K, Rath, V.L, Dai, S.C, Fletterick, R.J, Hwang, P.K.
Deposit date:1996-05-30
Release date:1996-12-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:A protein phosphorylation switch at the conserved allosteric site in GP.
Science, 273, 1996
2Z4J
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BU of 2z4j by Molmil
Crystal structure of AR LBD with SHP peptide NR Box 2
Descriptor: 5-ALPHA-DIHYDROTESTOSTERONE, Androgen receptor, Nuclear receptor 0B2
Authors:Jouravel, N, Fletterick, R.J.
Deposit date:2007-06-19
Release date:2007-12-04
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Interaction between the androgen receptor and a segment of its corepressor SHP
Acta Crystallogr.,Sect.D, 63, 2007
3I00
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BU of 3i00 by Molmil
Crystal Structure of the huntingtin interacting protein 1 coiled coil domain
Descriptor: Huntingtin-interacting protein 1
Authors:Wilbur, J.D, Hwang, P.K, Brodsky, F.M, Fletterick, R.J.
Deposit date:2009-06-24
Release date:2010-02-23
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Accommodation of structural rearrangements in the huntingtin-interacting protein 1 coiled-coil domain.
Acta Crystallogr.,Sect.D, 66, 2010
3LVG
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BU of 3lvg by Molmil
Crystal structure of a clathrin heavy chain and clathrin light chain complex
Descriptor: Clathrin heavy chain 1, Clathrin light chain B
Authors:Wilbur, J.D, Hwang, P.K, Ybe, J.A, Lane, M, Sellers, B.D, Jacobson, M.P, Fletterick, R.J, Brodsky, F.M.
Deposit date:2010-02-20
Release date:2010-06-09
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (7.94 Å)
Cite:Conformation switching of clathrin light chain regulates clathrin lattice assembly.
Dev.Cell, 18, 2010
3LVH
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BU of 3lvh by Molmil
Crystal structure of a clathrin heavy chain and clathrin light chain complex
Descriptor: Clathrin heavy chain 1, Clathrin light chain B
Authors:Wilbur, J.D, Hwang, P.K, Ybe, J.A, Lane, M, Sellers, B.D, Jacobson, M.P, Fletterick, R.J, Brodsky, F.M.
Deposit date:2010-02-20
Release date:2010-06-09
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (9 Å)
Cite:Conformation switching of clathrin light chain regulates clathrin lattice assembly.
Dev.Cell, 18, 2010
2NCD
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BU of 2ncd by Molmil
NCD (NON-CLARET DISJUNCTIONAL) DIMER FROM D. MELANOGASTER
Descriptor: ADENOSINE-5'-DIPHOSPHATE, PROTEIN (Kinesin motor NCD), SULFATE ION
Authors:Sablin, E.P, Case, R.B, Dai, S.C, Hart, C.L, Ruby, A, Vale, R.D, Fletterick, R.J.
Deposit date:1999-06-04
Release date:1999-06-09
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Direction determination in the minus-end-directed kinesin motor ncd.
Nature, 395, 1998
3COB
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BU of 3cob by Molmil
Structural Dynamics of the Microtubule binding and regulatory elements in the Kinesin-like Calmodulin binding protein
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Kinesin heavy chain-like protein, MAGNESIUM ION
Authors:Vinogradova, M.V, Malanina, G.G, Reddy, V, Reddy, A.S.N, Fletterick, R.J.
Deposit date:2008-03-27
Release date:2008-06-24
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural dynamics of the microtubule binding and regulatory elements in the kinesin-like calmodulin binding protein.
J.Struct.Biol., 163, 2008
3CNZ
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BU of 3cnz by Molmil
Structural dynamics of the microtubule binding and regulatory elements in the kinesin-like calmodulin binding protein
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Kinesin heavy chain-like protein, MAGNESIUM ION
Authors:Vinogradova, M.V, Malanina, G.G, Reddy, V, Reddy, A.S.N, Fletterick, R.J.
Deposit date:2008-03-26
Release date:2008-06-17
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structural dynamics of the microtubule binding and regulatory elements in the kinesin-like calmodulin binding protein.
J.Struct.Biol., 163, 2008
3F7D
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BU of 3f7d by Molmil
SF-1 LBD bound by phosphatidylcholine
Descriptor: (2S)-2-{[(1R)-1-hydroxyhexadecyl]oxy}-3-{[(1R)-1-hydroxyoctadecyl]oxy}propyl 2-(trimethylammonio)ethyl phosphate, Peroxisome proliferator-activated receptor gamma coactivator 1-alpha, nuclear receptor SF-1
Authors:Sablin, E.P, Fletterick, R.J.
Deposit date:2008-11-07
Release date:2008-12-09
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structure of SF-1 bound by different phospholipids: evidence for regulatory ligands.
Mol.Endocrinol., 23, 2009
1EWL
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BU of 1ewl by Molmil
CRYSTAL STRUCTURE OF CRUZAIN BOUND TO WRR-99
Descriptor: CRUZAIN, N-[3-CARBOXY-2-HYDROXY-PROPIONYL]-D-HOMOPHENYLALANYL-AMINO-2-METHYLBUTANE
Authors:Brinen, L.S, Gillmor, S.A, Fletterick, R.J.
Deposit date:2000-04-26
Release date:2003-06-10
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal Structure of Cruzain bound to WRR-99
To be Published
1EWM
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BU of 1ewm by Molmil
THE CYSTEINE PROTEASE CRUZAIN BOUND TO WRR-112
Descriptor: CRUZAIN, N-[3-CARBOXY-2-HYDROXY-PROPIONYL]-L-HOMOPHENYLALANYL-AMINO-2-METHYLBUTANE
Authors:Brinen, L.S, Gillmor, S.A, Fletterick, R.J.
Deposit date:2000-04-26
Release date:2003-06-10
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal Structure of Cruzain bound to WRR-112
To be Published
1EWO
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BU of 1ewo by Molmil
THE CYSTEINE PROTEASE CRUZAIN BOUND TO WRR-204
Descriptor: CRUZAIN, N-[N'-BENZYLOXYCARBONYL-PHENYLALANINYL]-3-AMINO-5-PHENYL-PENTANE-1-SULFONIC ACID PHENYL ESTER
Authors:Brinen, L.S, Gillmor, S.A, Fletterick, R.J.
Deposit date:2000-04-26
Release date:2003-06-10
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal Structure of Cruzain bound to WRR-204
To be Published
1A0Q
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BU of 1a0q by Molmil
29G11 COMPLEXED WITH PHENYL [1-(1-N-SUCCINYLAMINO)PENTYL] PHOSPHONATE
Descriptor: 29G11 FAB (HEAVY CHAIN), 29G11 FAB (LIGHT CHAIN), PHENYL[1-(N-SUCCINYLAMINO)PENTYL]PHOSPHONATE, ...
Authors:Buchbinder, J.L, Stephenson, R.C, Scanlan, T.S, Fletterick, R.J.
Deposit date:1997-12-05
Release date:1999-03-02
Last modified:2023-08-02
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:A comparison of the crystallographic structures of two catalytic antibodies with esterase activity.
J.Mol.Biol., 282, 1998
1AZZ
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BU of 1azz by Molmil
FIDDLER CRAB COLLAGENASE COMPLEXED TO ECOTIN
Descriptor: COLLAGENASE, ECOTIN
Authors:Perona, J.J, Fletterick, R.J.
Deposit date:1997-11-24
Release date:1998-02-25
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structure of an ecotin-collagenase complex suggests a model for recognition and cleavage of the collagen triple helix.
Biochemistry, 36, 1997
1BF6
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BU of 1bf6 by Molmil
PHOSPHOTRIESTERASE HOMOLOGY PROTEIN FROM ESCHERICHIA COLI
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, GLYCEROL, PHOSPHOTRIESTERASE HOMOLOGY PROTEIN, ...
Authors:Buchbinder, J.L, Stephenson, R.C, Scanlan, T.S, Fletterick, R.J.
Deposit date:1998-05-27
Release date:1999-06-08
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Biochemical characterization and crystallographic structure of an Escherichia coli protein from the phosphotriesterase gene family.
Biochemistry, 37, 1998
1BRA
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BU of 1bra by Molmil
RELOCATING A NEGATIVE CHARGE IN THE BINDING POCKET OF TRYPSIN
Descriptor: BENZAMIDINE, CALCIUM ION, TRYPSIN
Authors:Perona, J.J, Mcgrath, M.E, Fletterick, R.J.
Deposit date:1992-12-17
Release date:1994-04-30
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Relocating a negative charge in the binding pocket of trypsin.
J.Mol.Biol., 230, 1993

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