Author results

5V0O
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RNA HAIRPIN STRUCTURE CONTAINING 2-MEIMPG ANALOGUE BOUND
Descriptor:RNA (25-MER), RNA (5'-R(*GP*CP*AP*CP*CP*UP*CP*A)-3'), 5'-O-[(S)-hydroxy(4-methyl-1H-imidazol-5-yl)phosphoryl]guanosine
Authors:Zhang, W., Tam, C.P., Szostak, J.W.
Deposit date:2017-02-28
Release date:2018-02-21
Last modified:2018-03-14
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural Rationale for the Enhanced Catalysis of Nonenzymatic RNA Primer Extension by a Downstream Oligonucleotide.
J. Am. Chem. Soc., 140, 2018
5V9Z
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RNA HAIRPIN STRUCTURE CONTAINING 2-MEIMPG ANALOGUE BOUND
Descriptor:RNA (25-MER), RNA (5'-R(P*GP*CP*AP*CP*CP*UP*CP*A)-3'), 5'-O-[(S)-hydroxy(4-methyl-1H-imidazol-5-yl)phosphoryl]guanosine
Authors:Zhang, W., Szostak, J.W.
Deposit date:2017-03-24
Release date:2018-02-21
Last modified:2018-03-14
Method:X-RAY DIFFRACTION (2.51 Å)
Cite:Structural Rationale for the Enhanced Catalysis of Nonenzymatic RNA Primer Extension by a Downstream Oligonucleotide.
J. Am. Chem. Soc., 140, 2018
5VCF
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RNA HAIRPIN STRUCTURE CONTAINING TETRALOOP/RECEPTOR MOTIF, COMPLEXED WITH 2-MEIMPG ANALOGUE
Descriptor:RNA (5'-R(*CP*UP*GP*CP*UP*GP*GP*CP*UP*AP*AP*GP*GP*CP*CP*CP*GP*AP*AP*AP*GP*G)-3'), RNA (5'-R(*CP*UP*AP*UP*GP*CP*CP*UP*GP*CP*UP*G)-3'), 5'-O-[(S)-hydroxy(4-methyl-1H-imidazol-5-yl)phosphoryl]guanosine
Authors:Zhang, W., Szostak, J.W.
Deposit date:2017-03-31
Release date:2018-02-21
Last modified:2018-03-14
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural Rationale for the Enhanced Catalysis of Nonenzymatic RNA Primer Extension by a Downstream Oligonucleotide.
J. Am. Chem. Soc., 140, 2018
5VCI
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RNA HAIRPIN STRUCTURE CONTAINING TETRALOOP/RECEPTOR MOTIF, COMPLEXED WITH 2-MEIMPG ANALOGUE
Descriptor:RNA (5'-R(*CP*UP*GP*CP*UP*GP*GP*CP*UP*AP*AP*GP*GP*CP*CP*CP*GP*AP*AP*AP*GP*G)-3'), RNA (5'-R(P*CP*UP*AP*UP*GP*CP*CP*UP*GP*CP*UP*G)-3'), 5'-O-[(S)-hydroxy(4-methyl-1H-imidazol-5-yl)phosphoryl]guanosine
Authors:Szostak, J.W., Zhang, W.
Deposit date:2017-03-31
Release date:2018-02-21
Last modified:2018-03-14
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural Rationale for the Enhanced Catalysis of Nonenzymatic RNA Primer Extension by a Downstream Oligonucleotide.
J. Am. Chem. Soc., 140, 2018
5VGW
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RNA HAIRPIN STRUCTURE CONTAINING TETRALOOP/RECEPTOR MOTIF
Descriptor:RNA (5'-R(*CP*UP*GP*CP*UP*GP*GP*CP*UP*AP*AP*GP*GP*CP*CP*CP*GP*AP*AP*AP*GP*G)-3'), RNA (5'-R(P*GP*CP*UP*AP*UP*GP*CP*CP*UP*GP*CP*UP*G)-3')
Authors:Zhang, W., Szostak, J.W.
Deposit date:2017-04-11
Release date:2018-02-21
Last modified:2018-03-14
Method:X-RAY DIFFRACTION (2.42 Å)
Cite:Structural Rationale for the Enhanced Catalysis of Nonenzymatic RNA Primer Extension by a Downstream Oligonucleotide.
J. Am. Chem. Soc., 140, 2018
5WBS
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CRYSTAL STRUCTURE OF FRIZZLED-7 CRD WITH AN INHIBITOR PEPTIDE FZ7-21
Descriptor:Frizzled-7,inhibitor peptide Fz7-21
Authors:Nile, A.H., Mukund, S., Hannoush, R.N., Wang, W.
Deposit date:2017-06-29
Release date:2018-04-18
Last modified:2018-05-30
Method:X-RAY DIFFRACTION (2.88 Å)
Cite:A selective peptide inhibitor of Frizzled 7 receptors disrupts intestinal stem cells.
Nat. Chem. Biol., 14, 2018
6AZ4
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RNA HAIRPIN COMPLEX WITH GUANOSINE DINUCLEOTIDE LIGAND G(5')PPP(5')G
Descriptor:RNA (32-MER), RNA (5'-R(*CP*AP*GP*CP*AP*GP*CP*AP*G)-3'), DIGUANOSINE-5'-TRIPHOSPHATE
Authors:Zhang, W., Szostak, J.W.
Deposit date:2017-09-09
Release date:2018-02-21
Last modified:2018-03-14
Method:X-RAY DIFFRACTION (2.98 Å)
Cite:Structural Rationale for the Enhanced Catalysis of Nonenzymatic RNA Primer Extension by a Downstream Oligonucleotide.
J. Am. Chem. Soc., 140, 2018
6BMD
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RNA HAIRPIN CONTAINING GPPPG-OLIGO TO MIMIC INTERMEDIATE FORMED BY ACTIVATED MONOMER AND ACTIVATED DOWNSTREAM HELPER
Descriptor:RNA (5'-R(P*GP*AP*GP*GP*UP*GP*(LCC)P*(LCC)P*GP*AP*GP*CP*GP*CP*GP*AP*AP*AP*GP*CP*GP*CP*UP*C)-3'), RNA (5'-D(*(GP3))-R(P*CP*AP*CP*CP*UP*CP*A)-3')
Authors:Zhang, W., Szostak, J.W.
Deposit date:2017-11-14
Release date:2018-02-21
Last modified:2018-03-14
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structural Rationale for the Enhanced Catalysis of Nonenzymatic RNA Primer Extension by a Downstream Oligonucleotide.
J. Am. Chem. Soc., 140, 2018
1YF3
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T4DAM IN COMPLEX WITH ADOHCY AND 13-MER OLIGONUCLEOTIDE MAKING NON- AND SEMI-SPECIFIC (~1/4) CONTACT
Descriptor:5'-D(*AP*CP*CP*AP*TP*GP*AP*TP*CP*TP*GP*AP*C)-3', 5'-D(*TP*GP*TP*CP*AP*GP*AP*TP*CP*AP*TP*GP*G)-3', DNA adenine methylase, ...
Authors:Horton, J.R., Liebert, K., Hattman, S., Jeltsch, A., Cheng, X.
Deposit date:2004-12-30
Release date:2005-05-17
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (2.29 Å)
Cite:Transition from Nonspecific to Specific DNA Interactions along the Substrate-Recognition Pathway of Dam Methyltransferase.
Cell(Cambridge,Mass.), 121, 2005
1YFJ
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T4DAM IN COMPLEX WITH ADOHCY AND 15-MER OLIGONUCLEOTIDE SHOWING SEMI-SPECIFIC AND SPECIFIC CONTACT
Descriptor:5'-D(*TP*CP*AP*CP*AP*GP*GP*AP*TP*CP*CP*TP*GP*TP*G)-3', DNA adenine methylase, CHLORIDE ION, ...
Authors:Horton, J.R., Liebert, K., Hattman, S., Jeltsch, A., Cheng, X.
Deposit date:2005-01-02
Release date:2005-05-17
Last modified:2018-01-31
Method:X-RAY DIFFRACTION (2.69 Å)
Cite:Transition from Nonspecific to Specific DNA Interactions along the Substrate-Recognition Pathway of Dam Methyltransferase.
Cell(Cambridge,Mass.), 121, 2005
1YFL
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T4DAM IN COMPLEX WITH SINEFUNGIN AND 16-MER OLIGONUCLEOTIDE SHOWING SEMI-SPECIFIC AND SPECIFIC CONTACT AND FLIPPED BASE
Descriptor:5'-D(P*TP*CP*AP*CP*AP*GP*GP*AP*TP*CP*CP*TP*GP*TP*GP*A)-3', DNA adenine methylase, SINEFUNGIN
Authors:Horton, J.R., Liebert, K., Hattman, S., Jeltsch, A., Cheng, X.
Deposit date:2005-01-03
Release date:2005-05-17
Last modified:2018-01-31
Method:X-RAY DIFFRACTION (3.09 Å)
Cite:Transition from Nonspecific to Specific DNA Interactions along the Substrate-Recognition Pathway of Dam Methyltransferase.
Cell(Cambridge,Mass.), 121, 2005