Author results

4RI2
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CRYSTAL STRUCTURE OF THE PHOTOPROTECTIVE PROTEIN PSBS FROM SPINACH
Descriptor:Photosystem II 22 kDa protein, chloroplastic, B-NONYLGLUCOSIDE, ...
Authors:Fan, M., Li, M., Chang, W.
Deposit date:2014-10-05
Release date:2015-08-12
Last modified:2015-09-16
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Crystal structures of the PsbS protein essential for photoprotection in plants.
Nat.Struct.Mol.Biol., 22, 2015
4RI3
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CRYSTAL STRUCTURE OF DCCD-MODIFIED PSBS FROM SPINACH
Descriptor:Photosystem II 22 kDa protein, chloroplastic, DICYCLOHEXYLUREA, ...
Authors:Fan, M., Li, M., Chang, W.
Deposit date:2014-10-05
Release date:2015-08-12
Last modified:2015-09-16
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Crystal structures of the PsbS protein essential for photoprotection in plants.
Nat.Struct.Mol.Biol., 22, 2015
4RT4
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CRYSTAL STRUCTURE OF DPY30 COMPLEXED WITH BRE2
Descriptor:Protein dpy-30 homolog, Peptide from COMPASS component BRE2
Authors:Zhang, H.M., Li, M., Chang, W.R.
Deposit date:2014-11-12
Release date:2015-10-07
Method:X-RAY DIFFRACTION (1.997 Å)
Cite:Structural implications of Dpy30 oligomerization for MLL/SET1 COMPASS H3K4 trimethylation
Protein Cell, 6, 2015
4RTA
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CYSTAL STRUCTURE OF THE DPY30 FOR MLL/SET1 COMPASS H3K4 TRIMETHYLATION
Descriptor:Protein dpy-30 homolog, FORMIC ACID
Authors:Zhang, H.M., Li, M., Chang, W.R.
Deposit date:2014-11-14
Release date:2015-10-07
Method:X-RAY DIFFRACTION (2.123 Å)
Cite:Structural implications of Dpy30 oligomerization for MLL/SET1 COMPASS H3K4 trimethylation.
Protein Cell, 6, 2015
5BPE
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CRYSTAL STRUCTURE OF EV71 3CPRO IN COMPLEX WITH A POTENT AND SELECTIVE INHIBITOR
Descriptor:EV71 3Cpro, (2~{S})-~{N}-[(1~{R},2~{S})-1-cyano-1-oxidanyl-3-[(3~{S})-2-oxidanylidenepiperidin-3-yl]propan-2-yl]-3-phenyl-2-[[(~{E})-3-phenylprop-2-enoyl]amino]propanamide
Authors:Luqing, S., Yin, Z.
Deposit date:2015-05-28
Release date:2015-11-25
Last modified:2016-01-20
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Cyanohydrin as an Anchoring Group for Potent and Selective Inhibitors of Enterovirus 71 3C Protease
J.Med.Chem., 58, 2015
6IH9
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ADENO-ASSOCIATED VIRUS 2 AT 2.8 ANG
Descriptor:Capsid protein VP1
Authors:Lou, Z.Y., Zhang, R.
Deposit date:2018-09-29
Release date:2019-07-03
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:Adeno-associated virus 2 bound to its cellular receptor AAVR.
Nat Microbiol, 4, 2019
6IHB
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ADENO-ASSOCIATED VIRUS 2 IN COMPLEX WITH AAVR
Descriptor:Dyslexia-associated protein KIAA0319-like protein, Capsid protein VP1
Authors:Lou, Z.Y., Zhang, R.
Deposit date:2018-09-29
Release date:2019-03-20
Last modified:2019-04-10
Method:ELECTRON MICROSCOPY (2.84 Å)
Cite:Adeno-associated virus 2 bound to its cellular receptor AAVR.
Nat Microbiol, 4, 2019
1OBM
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RECOMBINANT SPERM WHALE MYOGLOBIN 29F/64Q/68F/122N MUTANT (MET)
Descriptor:MYOGLOBIN, SULFATE ION, PROTOPORPHYRIN IX CONTAINING FE
Authors:Brucker, E.A., Lile, R.A., Phillips Jr., G.N.
Deposit date:1997-12-19
Release date:1998-04-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Solution and crystal structures of a sperm whale myoglobin triple mutant that mimics the sulfide-binding hemoglobin from Lucina pectinata.
J.Biol.Chem., 273, 1998
1U6Q
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SUBSTITUTED 2-NAPHTHAMADINE INHIBITORS OF UROKINASE
Descriptor:Urokinase-type plasminogen activator, TRANS-6-(2-PHENYLCYCLOPROPYL)-NAPHTHALENE-2-CARBOXAMIDINE
Authors:Bruncko, M., McClellan, W., Wendt, M.D., Sauer, D.R., Geyer, A., Dalton, C.R., Kaminski, M.K., Nienaber, V.L., Rockway, T.R., Giranda, V.L.
Deposit date:2004-07-30
Release date:2004-10-19
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.02 Å)
Cite:Naphthamidine urokinase plasminogen activator inhibitors with improved pharmacokinetic properties.
Bioorg.Med.Chem.Lett., 15, 2005
2GER
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CRYSTAL STRUCTURE AND OXIDATIVE MECHANISM OF HUMAN PYRROLINE-5-CARBOXYLATE REDUCTASE
Descriptor:Pyrroline-5-carboxylate reductase 1
Authors:Meng, Z., Lou, Z., Liu, Z., Rao, Z.
Deposit date:2006-03-20
Release date:2006-09-19
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Crystal structure of human pyrroline-5-carboxylate reductase
J.Mol.Biol., 359, 2006
2GR9
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CRYSTAL STRUCTURE OF P5CR COMPLEXED WITH NADH
Descriptor:Pyrroline-5-carboxylate reductase 1, 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, GLUTAMIC ACID
Authors:Meng, Z., Lou, Z., Liu, Z., Rao, Z.
Deposit date:2006-04-23
Release date:2006-10-03
Last modified:2013-11-06
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Crystal structure of human pyrroline-5-carboxylate reductase
J.Mol.Biol., 359, 2006
2GRA
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CRYSTAL STRUCTURE OF HUMAN PYRROLINE-5-CARBOXYLATE REDUCTASE COMPLEXED WITH NADP
Descriptor:Pyrroline-5-carboxylate reductase 1, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, GLUTAMIC ACID
Authors:Meng, Z., Lou, Z., Liu, Z., Rao, Z.
Deposit date:2006-04-23
Release date:2006-10-03
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Crystal structure of human pyrroline-5-carboxylate reductase
J.Mol.Biol., 359, 2006
2M6X
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STRUCTURE OF THE P7 CHANNEL OF HEPATITIS C VIRUS, GENOTYPE 5A
Descriptor:p7
Authors:OuYang, B., Chou, J.J.
Deposit date:2013-04-12
Release date:2013-06-12
Last modified:2014-01-29
Method:SOLUTION NMR
Cite:Unusual architecture of the p7 channel from hepatitis C virus
Nature, 498, 2013
2N2N
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TOM1 NEGATIVELY MODULATES BINDING OF TOLLIP TO PHOSPHATIDYLINOSITOL 3-PHOSPHATE VIA A COUPLED FOLDING AND BINDING MECHANISM
Descriptor:Target of Myb protein 1
Authors:Xiao, S., Armstrong, G., Capelluto, D.
Deposit date:2015-05-11
Release date:2015-09-16
Last modified:2015-10-21
Method:SOLUTION NMR
Cite:Tom1 Modulates Binding of Tollip to Phosphatidylinositol 3-Phosphate via a Coupled Folding and Binding Mechanism.
Structure, 23, 2015
2N31
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TOM1 NEGATIVELY MODULATES BINDING OF TOLLIP TO PHOSPHATIDYLINOSITOL 3-PHOSPHATE VIA A COUPLED FOLDING AND BINDING MECHANISM
Descriptor:Toll interacting protein variant
Authors:Xiao, S., Armstrong, G., Capelluto, D.
Deposit date:2015-05-19
Release date:2015-09-16
Last modified:2015-10-21
Method:SOLUTION NMR
Cite:Tom1 Modulates Binding of Tollip to Phosphatidylinositol 3-Phosphate via a Coupled Folding and Binding Mechanism.
Structure, 23, 2015
2WGO
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STRUCTURE OF RANASPUMIN-2, A SURFACTANT PROTEIN FROM THE FOAM NESTS OF A TROPICAL FROG
Descriptor:RANASPUMIN-2
Authors:Mackenzie, C.D., Smith, B.O., Kennedy, M.W., Cooper, A.
Deposit date:2009-04-21
Release date:2009-06-23
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Ranaspumin-2: Structure and Function of a Surfactant Protein from the Foam Nests of a Tropical Frog.
Biophys.J., 96, 2009
3K3P
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CRYSTAL STRUCTURE OF THE APO FORM OF D-ALANINE:D-ALANINE LIGASE (DDL) FROM STREPTOCOCCUS MUTANS
Descriptor:D-alanine--D-alanine ligase
Authors:Lu, Y.
Deposit date:2009-10-03
Release date:2010-09-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.23 Å)
Cite:Crystal structure of the Apo form of D-Alanine:D-Alanine ligase (DDl) from Streptococcus mutans
Protein Pept.Lett., 17, 2010
3PL5
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FATTY ACID BINDING PROTEIN
Descriptor:Putative uncharacterized protein, PALMITIC ACID
Authors:Lu, Y.Z.
Deposit date:2010-11-13
Release date:2011-12-07
Method:X-RAY DIFFRACTION (2.04 Å)
Cite:Lipid binding protein
To be Published
4FWX
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AQUOFERRIC F33Y CUB MYOGLOBIN (F33Y L29H F43H SPERM WHALE MYOGLOBIN)
Descriptor:Myoglobin, PROTOPORPHYRIN IX CONTAINING FE
Authors:Gao, Y.-G., Stoner-Ma, D., Robinson, H., Petrik, I.D., Miner, K.D., Lu, Y.
Deposit date:2012-07-02
Release date:2012-07-18
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:A Designed Functional Metalloenzyme that Reduces O(2) to H(2) O with Over One Thousand Turnovers.
Angew.Chem.Int.Ed.Engl., 51, 2012
4FWY
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F33Y CUB MYOGLOBIN (F33Y L29H F43H SPERM WHALE MYOGLOBIN) WITH COPPER BOUND
Descriptor:Myoglobin, PROTOPORPHYRIN IX CONTAINING FE, COPPER (II) ION
Authors:Gao, Y.-G., Robinson, H., Petrik, I.D., Miner, K.D., Lu, Y.
Deposit date:2012-07-02
Release date:2012-07-18
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:A Designed Functional Metalloenzyme that Reduces O(2) to H(2) O with Over One Thousand Turnovers.
Angew.Chem.Int.Ed.Engl., 51, 2012
4FWZ
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AQUOFERRIC CUB MYOGLOBIN (L29H F43H SPERM WHALE MYOGLOBIN)
Descriptor:Myoglobin, PROTOPORPHYRIN IX CONTAINING FE
Authors:Gao, Y.-G., Robinson, H., Petrik, I.D., Miner, K.D., Lu, Y.
Deposit date:2012-07-02
Release date:2012-07-18
Last modified:2012-11-14
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:A Designed Functional Metalloenzyme that Reduces O(2) to H(2) O with Over One Thousand Turnovers.
Angew.Chem.Int.Ed.Engl., 51, 2012
4H1J
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CRYSTAL STRUCTURE OF PYK2 WITH THE PYRAZOLE 13A
Descriptor:Protein-tyrosine kinase 2-beta, 1-[3-tert-butyl-1-(4-methylphenyl)-1H-pyrazol-5-yl]-3-[3-(4-methoxy-2-methylphenyl)-1H-pyrazol-5-yl]urea
Authors:Han, S.
Deposit date:2012-09-10
Release date:2012-11-28
Last modified:2012-12-12
Method:X-RAY DIFFRACTION (2 Å)
Cite:Identification of novel series of pyrazole and indole-urea based DFG-out PYK2 inhibitors.
Bioorg.Med.Chem.Lett., 22, 2012
4H1M
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CRYSTAL STRUCTURE OF PYK2 WITH THE INDOLE 10C
Descriptor:Protein-tyrosine kinase 2-beta, 7-({[3-tert-butyl-1-(4-methylphenyl)-1H-pyrazol-5-yl]carbamoyl}amino)-N-(propan-2-yl)-1H-indole-2-carboxamide
Authors:Han, S.
Deposit date:2012-09-10
Release date:2012-11-28
Last modified:2012-12-12
Method:X-RAY DIFFRACTION (1.99 Å)
Cite:Identification of novel series of pyrazole and indole-urea based DFG-out PYK2 inhibitors.
Bioorg.Med.Chem.Lett., 22, 2012
4HEU
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CRYSTAL STRUCTURE OF PDE10A WITH A BIARYL ETHER INHIBITOR ((1-(3-(4-((1H-BENZO[D]IMIDAZOL-2-YL)AMINO)PHENOXY)PYRIDIN-2-YL)PIPERIDIN-4-YL)METHANOL)
Descriptor:cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A, ZINC ION, SULFATE ION, ...
Authors:Chmait, S., Jordan, S.
Deposit date:2012-10-04
Release date:2012-12-12
Method:X-RAY DIFFRACTION (2 Å)
Cite:Discovery of selective biaryl ethers as PDE10A inhibitors: Improvement in potency and mitigation of Pgp-mediated efflux.
Bioorg.Med.Chem.Lett., 22, 2012
4HF4
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CRYSTAL STRUCTURE OF PDE10A WITH A BIARYL ETHER INHIBITOR (1-(1-(3-(4-(BENZO[D]THIAZOL-2-YLAMINO)PHENOXY)PYRAZIN-2-YL)PIPERIDIN-4-YL)ETHANOL)
Descriptor:cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A, ZINC ION, SULFATE ION, ...
Authors:Chmait, S., Jordan, S.
Deposit date:2012-10-04
Release date:2012-12-12
Method:X-RAY DIFFRACTION (2 Å)
Cite:Discovery of selective biaryl ethers as PDE10A inhibitors: Improvement in potency and mitigation of Pgp-mediated efflux.
Bioorg.Med.Chem.Lett., 22, 2012