Author results

5YDG
  • Download 5ydg
  • View 5ydg
Molmil generated image of 5ydg
CRYSTAL STRUCTURE OF THE ARABIDOPSIS THALIANA CHLOROPLAST RNA EDITING FACTORS 2(MORF2)
Descriptor:Multiple organellar RNA editing factor 2, chloroplastic
Authors:Wang, X., Yang, J.Y., Wang, Y.L., Gao, Y.S.
Deposit date:2017-09-13
Release date:2017-12-20
Last modified:2018-01-17
Method:X-RAY DIFFRACTION (2.405 Å)
Cite:Crystal structure of the chloroplast RNA editing factor MORF2
Biochem. Biophys. Res. Commun., 495, 2018
6NII
  • Download 6nii
  • View 6nii
Molmil generated image of 6nii
CRYSTAL STRUCTURE OF RAVD (RESIDUES 1-200) FROM LEGIONELLA PNEUMOPHILA (STRAIN CORBY)
Descriptor:Uncharacterized protein RavD
Authors:Wang, X., Zhou, Y., Zhu, Y.
Deposit date:2018-12-28
Release date:2019-05-22
Last modified:2020-01-08
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:A bacterial effector deubiquitinase specifically hydrolyses linear ubiquitin chains to inhibit host inflammatory signalling.
Nat Microbiol, 4, 2019
6NJD
  • Download 6njd
  • View 6njd
Molmil generated image of 6njd
CRYSTAL STRUCTURE OF RAVD (RESIDUES 1-200) FROM LEGIONELLA PNEUMOPHILA (STRAIN CORBY) COMPLEXED WITH MET-1 LINKED DI-UBIQUITIN
Descriptor:Di-ubiquitin, RavD, MAGNESIUM ION
Authors:Wang, X., Zhou, Y., Zhu, Y.
Deposit date:2019-01-03
Release date:2019-05-22
Last modified:2020-01-08
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:A bacterial effector deubiquitinase specifically hydrolyses linear ubiquitin chains to inhibit host inflammatory signalling.
Nat Microbiol, 4, 2019
2MTC
  • Download 2mtc
  • View 2mtc
Molmil generated image of 2mtc
STRUCTURE OF DECORIN BINDING PROTEIN A FROM STRAIN N40 OF BORRELIA BURGDORFERI
Descriptor:Decorin-binding protein A
Authors:Wang, X., Morgan, A.
Deposit date:2014-08-16
Release date:2015-03-25
Last modified:2015-04-29
Method:SOLUTION NMR
Cite:Structural mechanisms underlying sequence-dependent variations in GAG affinities of decorin binding protein A, a Borrelia burgdorferi adhesin.
Biochem.J., 467, 2015
2MTD
  • Download 2mtd
  • View 2mtd
Molmil generated image of 2mtd
STRCUCTURE OF DECORIN BINDING PROTEIN A FROM STRAIN PBR OF BORRELIA GARINII
Descriptor:Decorin binding protein A
Authors:Wang, X., Morgan, A.
Deposit date:2014-08-16
Release date:2015-03-25
Last modified:2015-04-29
Method:SOLUTION NMR
Cite:Structural mechanisms underlying sequence-dependent variations in GAG affinities of decorin binding protein A, a Borrelia burgdorferi adhesin.
Biochem.J., 467, 2015
2MVG
  • Download 2mvg
  • View 2mvg
Molmil generated image of 2mvg
SOLUTION STRUCTURE OF DECORIN BINDING PROTEIN B FROM BORRELIA BURGDORFERI
Descriptor:Decorin-binding protein B
Authors:Wang, X., Feng, W.
Deposit date:2014-10-03
Release date:2015-08-19
Last modified:2016-01-27
Method:SOLUTION NMR
Cite:Structure of decorin binding protein B from Borrelia burgdorferi and its interactions with glycosaminoglycans.
Biochim.Biophys.Acta, 1854, 2015
2P4H
  • Download 2p4h
  • View 2p4h
Molmil generated image of 2p4h
CRYSTAL STRUCTURE OF VESTITONE REDUCTASE FROM ALFALFA (MEDICAGO SATIVA L.)
Descriptor:Vestitone reductase
Authors:Wang, X., Shao, H., Dixon, R.A.
Deposit date:2007-03-12
Release date:2007-05-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Crystal Structure of Vestitone Reductase from Alfalfa (Medicago sativa L.).
J.Mol.Biol., 369, 2007
3HBF
  • Download 3hbf
  • View 3hbf
Molmil generated image of 3hbf
STRUCTURE OF UGT78G1 COMPLEXED WITH MYRICETIN AND UDP
Descriptor:Flavonoid 3-O-glucosyltransferase, URIDINE-5'-DIPHOSPHATE, 3,5,7-TRIHYDROXY-2-(3,4,5-TRIHYDROXYPHENYL)-4H-CHROMEN-4-ONE
Authors:Wang, X., Modolo, L., Li, L., Dixon, R.
Deposit date:2009-05-04
Release date:2009-09-01
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structures of glycosyltransferase UGT78G1 reveal the molecular basis for glycosylation and deglycosylation of (iso)flavonoids.
J.Mol.Biol., 392, 2009
3HBJ
  • Download 3hbj
  • View 3hbj
Molmil generated image of 3hbj
STRUCTURE OF UGT78G1 COMPLEXED WITH UDP
Descriptor:Flavonoid 3-O-glucosyltransferase, URIDINE-5'-DIPHOSPHATE
Authors:Wang, X., Modolo, L., Li, L., Dixon, R.
Deposit date:2009-05-04
Release date:2009-09-01
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structures of glycosyltransferase UGT78G1 reveal the molecular basis for glycosylation and deglycosylation of (iso)flavonoids.
J.Mol.Biol., 392, 2009
4EJR
  • Download 4ejr
  • View 4ejr
Molmil generated image of 4ejr
CRYSTAL STRUCTURE OF MAJOR CAPSID PROTEIN S DOMAIN FROM RABBIT HEMORRHAGIC DISEASE VIRUS
Descriptor:Major capsid protein VP60
Authors:Xu, F., Ma, J., Zhang, K., Wang, X., Sun, F.
Deposit date:2012-04-07
Release date:2013-01-30
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (2 Å)
Cite:Atomic model of rabbit hemorrhagic disease virus by cryo-electron microscopy and crystallography.
Plos Pathog., 9, 2013
5K6S
  • Download 5k6s
  • View 5k6s
Molmil generated image of 5k6s
THE STRUCTURE OF THE PP2A B56 SUBUNIT BUBR1 COMPLEX
Descriptor:Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform, BubR1
Authors:Page, R., Wang, X., Bajaj, R., Peti, W.
Deposit date:2016-05-25
Release date:2016-12-07
Last modified:2019-12-18
Method:X-RAY DIFFRACTION (2.794 Å)
Cite:Expanding the PP2A Interactome by Defining a B56-Specific SLiM.
Structure, 24, 2016
5SW9
  • Download 5sw9
  • View 5sw9
Molmil generated image of 5sw9
THE STRUCTURE OF THE PP2A B56 SUBUNIT REPOMAN COMPLEX
Descriptor:Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform, RepoMan
Authors:Page, R., Wang, X., Bajaj, R., Peti, W.
Deposit date:2016-08-08
Release date:2016-11-30
Last modified:2019-12-18
Method:X-RAY DIFFRACTION (2.846 Å)
Cite:Expanding the PP2A Interactome by Defining a B56-Specific SLiM.
Structure, 24, 2016
5SWF
  • Download 5swf
  • View 5swf
Molmil generated image of 5swf
THE STRUCTURE OF THE PP2A B56 SUBUNIT DOUBLE PHOSPHORYLATED BUBR1 COMPLEX
Descriptor:Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform, Double phosphorylated BubR1
Authors:Page, R., Wang, X., Bajaj, R., Peti, W.
Deposit date:2016-08-08
Release date:2016-11-30
Last modified:2019-12-18
Method:X-RAY DIFFRACTION (2.818 Å)
Cite:Expanding the PP2A Interactome by Defining a B56-Specific SLiM.
Structure, 24, 2016
5Y18
  • Download 5y18
  • View 5y18
Molmil generated image of 5y18
CRYSTAL STRUCTURE OF DAXX HELICAL BUNDLE DOMAIN IN COMPLEX WITH ATRX
Descriptor:Death domain-associated protein 6, Transcriptional regulator ATRX
Authors:Chen, Y., Wang, X.
Deposit date:2017-07-19
Release date:2018-05-30
Method:X-RAY DIFFRACTION (2.202 Å)
Cite:Structural basis for DAXX interaction with ATRX
Protein Cell, 8, 2017
6H22
  • Download 6h22
  • View 6h22
Molmil generated image of 6h22
CRYSTAL STRUCTURE OF MDM2 BOUND TO A STAPLED PEPTIDE
Descriptor:E3 ubiquitin-protein ligase Mdm2, Stapled peptide, 12-(dimethylamino)-3,10-diethyl-N,N,N-trimethyl-3,10-dihydrodibenzo[3,4:7,8]cycloocta[1,2-d:5,6-d']bis([1,2,3]triazole)-5-aminium
Authors:Wang, X., Sharma, K., Spring, D.R., Hyvonen, M.
Deposit date:2018-07-12
Release date:2019-07-31
Last modified:2019-09-11
Method:X-RAY DIFFRACTION (2.006 Å)
Cite:Water-soluble, stable and azide-reactive strained dialkynes for biocompatible double strain-promoted click chemistry.
Org.Biomol.Chem., 17, 2019
6NUC
  • Download 6nuc
  • View 6nuc
Molmil generated image of 6nuc
STRUCTURE OF CALCINEURIN IN COMPLEX WITH NHE1 PEPTIDE
Descriptor:Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform, Calcineurin subunit B type 1, Sodium/hydrogen exchanger 1, ...
Authors:Wang, X., Page, R., Peti, W.
Deposit date:2019-01-31
Release date:2019-07-03
Last modified:2019-12-18
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Molecular basis for the binding and selective dephosphorylation of Na+/H+exchanger 1 by calcineurin.
Nat Commun, 10, 2019
6NUF
  • Download 6nuf
  • View 6nuf
Molmil generated image of 6nuf
STRUCTURE OF CALCINEURIN IN COMPLEX WITH NHE1 PEPTIDE
Descriptor:Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform, Calcineurin subunit B type 1, Sodium/hydrogen exchanger 1, ...
Authors:Wang, X., Page, R., Peti, W.
Deposit date:2019-01-31
Release date:2019-07-03
Last modified:2019-12-18
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Molecular basis for the binding and selective dephosphorylation of Na+/H+exchanger 1 by calcineurin.
Nat Commun, 10, 2019
6NUU
  • Download 6nuu
  • View 6nuu
Molmil generated image of 6nuu
STRUCTURE OF CALCINEURIN MUTANT IN COMPLEX WITH NHE1 PEPTIDE
Descriptor:Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform, Calcineurin subunit B type 1, Sodium/hydrogen exchanger 1, ...
Authors:Wang, X., Page, R., Peti, W.
Deposit date:2019-02-02
Release date:2019-07-03
Last modified:2019-12-18
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Molecular basis for the binding and selective dephosphorylation of Na+/H+exchanger 1 by calcineurin.
Nat Commun, 10, 2019
6V5L
  • Download 6v5l
  • View 6v5l
Molmil generated image of 6v5l
THE HADDOCK STRUCTURE MODEL OF GDP KRAS IN COMPLEX WITH ITS ALLOSTERIC INHIBITOR E22
Descriptor:GTPase KRas, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ...
Authors:Wang, X., Gupta, A.K., Prakash, P., Putkey, J.P., Gorfe, A.A.
Deposit date:2019-12-04
Release date:2019-12-18
Method:SOLUTION NMR
Cite:Multi target ensemble based virtual screening yields novel allosteric KRAS inhibitors at high success rate
Chemical Biology & Drug Design, 94, 2019
4CDQ
  • Download 4cdq
  • View 4cdq
Molmil generated image of 4cdq
CRYSTAL STRUCTURE OF HUMAN ENTEROVIRUS 71 IN COMPLEX WITH THE UNCOATING INHIBITOR GPP2
Descriptor:VP1, VP2, VP3, ...
Authors:DeColibus, L., Wang, X., Spyrou, J.A.B., Kelly, J., Ren, J., Grimes, J., Puerstinger, G., Stonehouse, N., Walter, T.S., Hu, Z., Wang, J., Li, X., Peng, W., Rowlands, D., Fry, E.E., Rao, Z., Stuart, D.I.
Deposit date:2013-11-05
Release date:2014-02-12
Last modified:2019-02-06
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:More-Powerful Virus Inhibitors from Structure-Based Analysis of Hev71 Capsid-Binding Molecules
Nat.Struct.Mol.Biol., 21, 2014
4CDU
  • Download 4cdu
  • View 4cdu
Molmil generated image of 4cdu
CRYSTAL STRUCTURE OF HUMAN ENTEROVIRUS 71 IN COMPLEX WITH THE UNCOATING INHIBITOR GPP3
Descriptor:VP1, VP2, VP3, ...
Authors:De Colibus, L., Wang, X., Spyrou, J.A.B., Kelly, J., Ren, J., Grimes, J., Puerstinger, G., Stonehouse, N., Walter, T.S., Hu, Z., Wang, J., Li, X., Peng, W., Rowlands, D., Fry, E.E., Rao, Z., Stuart, D.I.
Deposit date:2013-11-06
Release date:2014-02-12
Last modified:2019-02-06
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:More-Powerful Virus Inhibitors from Structure-Based Analysis of Hev71 Capsid-Binding Molecules
Nat.Struct.Mol.Biol., 21, 2014
4CDW
  • Download 4cdw
  • View 4cdw
Molmil generated image of 4cdw
CRYSTAL STRUCTURE OF HUMAN ENTEROVIRUS 71 IN COMPLEX WITH THE UNCOATING INHIBITOR GPP4
Descriptor:VP1, VP2, VP3, ...
Authors:De Colibus, L., Wang, X., Spyrou, J.A.B., Kelly, J., Ren, J., Grimes, J., Puerstinger, G., Stonehouse, N., Walter, T.S., Hu, Z., Wang, J., Li, X., Peng, W., Rowlands, D., Fry, E.E., Rao, Z., Stuart, D.I.
Deposit date:2013-11-06
Release date:2014-02-12
Last modified:2019-02-06
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:More-Powerful Virus Inhibitors from Structure-Based Analysis of Hev71 Capsid-Binding Molecules
Nat.Struct.Mol.Biol., 21, 2014
4CDX
  • Download 4cdx
  • View 4cdx
Molmil generated image of 4cdx
CRYSTAL STRUCTURE OF HUMAN ENTEROVIRUS 71 IN COMPLEX WITH THE UNCOATING INHIBITOR GPP12
Descriptor:VP1, VP2, VP3, ...
Authors:De Colibus, L., Wang, X., Spyrou, J.A.B., Kelly, J., Ren, J., Grimes, J., Puerstinger, G., Stonehouse, N., Walter, T.S., Hu, Z., Wang, J., Li, X., Peng, W., Rowlands, D., Fry, E.E., Rao, Z., Stuart, D.I.
Deposit date:2013-11-07
Release date:2014-02-12
Last modified:2019-02-06
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:More-Powerful Virus Inhibitors from Structure-Based Analysis of Hev71 Capsid-Binding Molecules.
Nat.Struct.Mol.Biol., 21, 2014
4CEW
  • Download 4cew
  • View 4cew
Molmil generated image of 4cew
CRYSTAL STRUCTURE OF HUMAN ENTEROVIRUS 71 IN COMPLEX WITH THE UNCOATING INHIBITOR ALD
Descriptor:VP1, VP2, VP3, ...
Authors:De Colibus, L., Wang, X., Spyrou, J.A.B., Kelly, J., Ren, J., Grimes, J., Puerstinger, G., Stonehouse, N., Walter, T.S., Hu, Z., Wang, J., Li, X., Peng, W., Rowlands, D., Fry, E.E., Rao, Z., Stuart, D.I.
Deposit date:2013-11-12
Release date:2014-02-12
Last modified:2019-02-06
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:More-Powerful Virus Inhibitors from Structure-Based Analysis of Hev71 Capsid-Binding Molecules.
Nat.Struct.Mol.Biol., 21, 2014
4CEY
  • Download 4cey
  • View 4cey
Molmil generated image of 4cey
CRYSTAL STRUCTURE OF HUMAN ENTEROVIRUS 71 IN COMPLEX WITH THE UNCOATING INHIBITOR NLD
Descriptor:VP1, VP2, VP3, ...
Authors:De Colibus, L., Wang, X., Spyrou, J.A.B., Kelly, J., Ren, J., Grimes, J., Puerstinger, G., Stonehouse, N., Walter, T.S., Hu, Z., Wang, J., Li, X., Peng, W., Rowlands, D., Fry, E.E., Rao, Z., Stuart, D.I.
Deposit date:2013-11-12
Release date:2014-02-12
Last modified:2014-03-19
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:More-Powerful Virus Inhibitors from Structure-Based Analysis of Hev71 Capsid-Binding Molecules
Nat.Struct.Mol.Biol., 21, 2014