Author results

5Z3W
  • Download 5z3w
  • View 5z3w
Molmil generated image of 5z3w
MALATE DEHYDROGENASE BINDS SILVER AT C113
Descriptor:Malate dehydrogenase, SILVER ION
Authors:Wang, H., Wang, M., Sun, H.
Deposit date:2018-01-09
Release date:2019-01-16
Method:X-RAY DIFFRACTION (2.29 Å)
Cite:Structure of silver-bound malate dehydrogenase
To Be Published
5ZCJ
  • Download 5zcj
  • View 5zcj
Molmil generated image of 5zcj
CRYSTAL STRUCTURE OF COMPLEX
Descriptor:Tudor-interacting repair regulator protein, TP53-binding protein 1
Authors:Wang, J., Yuan, Z., Cui, Y., Xie, R., Wang, M., Ma, Y., Yu, X., Liu, X.
Deposit date:2018-02-17
Release date:2018-06-27
Method:X-RAY DIFFRACTION (2.004 Å)
Cite:Crystal structure of complex
To Be Published
4WAB
  • Download 4wab
  • View 4wab
Molmil generated image of 4wab
CRYSTAL STRUCTURE OF MPGES1 SOLVED BY NATIVE-SAD PHASING
Descriptor:Prostaglandin E synthase,Leukotriene C4 synthase, GLUTATHIONE, 2-[[2,6-bis(chloranyl)-3-[(2,2-dimethylpropanoylamino)methyl]phenyl]amino]-1-methyl-6-(2-methyl-2-oxidanyl-propoxy)-N-[2,2,2-tris(fluoranyl)ethyl]benzimidazole-5-carboxamide
Authors:Weinert, T., Li, D., Howe, N., Caffrey, M., Wang, M.
Deposit date:2014-08-29
Release date:2014-12-10
Last modified:2015-02-11
Method:X-RAY DIFFRACTION (2.704 Å)
Cite:Fast native-SAD phasing for routine macromolecular structure determination.
Nat.Methods, 12, 2015
3ZJ6
  • Download 3zj6
  • View 3zj6
Molmil generated image of 3zj6
CRYSTAL OF RAUCAFFRICINE GLUCOSIDASE IN COMPLEX WITH INHIBITOR
Descriptor:RAUCAFFRICINE-O-BETA-D-GLUCOSIDASE, SULFATE ION, (1R,2S,3S,4R,5R)-4-(cyclohexylmethylamino)-5-(hydroxymethyl)cyclopentane-1,2,3-triol
Authors:Xia, L., Lin, H., Panjikar, S., Ruppert, M., Castiglia, A., Rajendran, C., Wang, M., Schuebel, H., Warzecha, H., Jaeger, V., Stoeckigt, J.
Deposit date:2013-01-17
Release date:2014-01-29
Last modified:2015-07-22
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Ligand Structures of Synthetic Deoxa-Pyranosylamines with Raucaffricine and Strictosidine Glucosidases Provide Structural Insights Into Their Binding and Inhibitory Behaviours.
J.Enzyme.Inhib.Med.Chem., 30, 2015
4ATD
  • Download 4atd
  • View 4atd
Molmil generated image of 4atd
CRYSTAL STRUCTURE OF NATIVE RAUCAFFRICINE GLUCOSIDASE
Descriptor:RAUCAFFRICINE-O-BETA-D-GLUCOSIDASE, SULFATE ION
Authors:Xia, L., Rajendran, C., Ruppert, M., Panjikar, S., Wang, M., Stoeckigt, J.
Deposit date:2012-05-05
Release date:2013-01-16
Last modified:2013-06-19
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:High Speed X-Ray Analysis of Plant Enzymes at Room Temperature
Phytochemistry, 91, 2013
4ATL
  • Download 4atl
  • View 4atl
Molmil generated image of 4atl
CRYSTAL STRUCTURE OF RAUCAFFRICINE GLUCOSIDASE IN COMPLEX WITH GLUCOSE
Descriptor:RAUCAFFRICINE-O-BETA-D-GLUCOSIDASE, BETA-D-GLUCOSE
Authors:Xia, L., Rajendran, C., Ruppert, M., Panjikar, S., Wang, M., Stoeckigt, J.
Deposit date:2012-05-08
Release date:2013-01-30
Last modified:2013-08-07
Method:X-RAY DIFFRACTION (2.52 Å)
Cite:High Speed X-Ray Analysis of Plant Enzymes at Room Temperature
Phytochemistry, 91, 2013
4R8T
  • Download 4r8t
  • View 4r8t
Molmil generated image of 4r8t
STRUCTURE OF JEV PROTEASE
Descriptor:Serine protease subunit NS2B, NS3, CHLORIDE ION
Authors:Nair, D.T., Weinert, T., Wang, M., Olieric, V.
Deposit date:2014-09-03
Release date:2014-12-24
Last modified:2015-08-12
Method:X-RAY DIFFRACTION (2.133 Å)
Cite:Fast native-SAD phasing for routine macromolecular structure determination.
Nat.Methods, 12, 2015
4R8U
  • Download 4r8u
  • View 4r8u
Molmil generated image of 4r8u
S-SAD STRUCTURE OF DINB-DNA COMPLEX
Descriptor:DNA polymerase IV, DNA, MAGNESIUM ION, ...
Authors:Kottur, J., Nair, D.T., Weinert, T., Oligeric, V., Wang, M.
Deposit date:2014-09-03
Release date:2015-01-14
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Fast native-SAD phasing for routine macromolecular structure determination
Nat.Methods, 12, 2015
4WAU
  • Download 4wau
  • View 4wau
Molmil generated image of 4wau
CRYSTAL STRUCTURE OF CENP-M SOLVED BY NATIVE-SAD PHASING
Descriptor:Centromere protein M
Authors:Weinert, T., Basilico, F., Cecatiello, V., Pasqualato, S., Wang, M.
Deposit date:2014-09-01
Release date:2014-12-10
Last modified:2015-02-11
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Fast native-SAD phasing for routine macromolecular structure determination.
Nat.Methods, 12, 2015
4WBQ
  • Download 4wbq
  • View 4wbq
Molmil generated image of 4wbq
CRYSTAL STRUCTURE OF THE EXONUCLEASE DOMAIN OF QIP (QDE-2 INTERACTING PROTEIN) SOLVED BY NATIVE-SAD PHASING.
Descriptor:QDE-2-interacting protein, CALCIUM ION
Authors:Boland, A., Weinert, T., Weichenrieder, O., Wang, M.
Deposit date:2014-09-03
Release date:2014-12-10
Last modified:2015-02-11
Method:X-RAY DIFFRACTION (2.693 Å)
Cite:Fast native-SAD phasing for routine macromolecular structure determination.
Nat.Methods, 12, 2015
5DWK
  • Download 5dwk
  • View 5dwk
Molmil generated image of 5dwk
DIACYLGLYCEROL KINASE SOLVED BY MULTI CRYSTAL MULTI ORIENTATION NATIVE SAD
Descriptor:Diacylglycerol kinase, (2R)-2,3-DIHYDROXYPROPYL(7Z)-PENTADEC-7-ENOATE, (2S)-2,3-DIHYDROXYPROPYL(7Z)-PENTADEC-7-ENOATE, ...
Authors:Weinert, T., Olieric, V., Finke, A.D., Li, D., Caffrey, M., Wang, M.
Deposit date:2015-09-22
Release date:2016-03-23
Method:X-RAY DIFFRACTION (2.601 Å)
Cite:Data-collection strategy for challenging native SAD phasing.
Acta Crystallogr D Struct Biol, 72, 2016
5FQ5
  • Download 5fq5
  • View 5fq5
Molmil generated image of 5fq5
CRYSTAL STRUCTURE OF CAS9-SGRNA-DNA COMPLEX SOLVED BY NATIVE SAD PHASING
Descriptor:SGRNA, CRISPR-ASSOCIATED ENDONUCLEASE CAS9/CSN1, TARGET DNA STRAND PROXIMAL FRAGMENT, ...
Authors:Olieric, V., Weinert, T., Finke, A., Anders, C., Jinek, M., Wang, M.
Deposit date:2015-12-07
Release date:2016-03-23
Method:X-RAY DIFFRACTION (2.136 Å)
Cite:Data-Collection Strategy for Challenging Native Sad Phasing.
Acta Crystallogr.,Sect.D, 72, 2016
5N6H
  • Download 5n6h
  • View 5n6h
Molmil generated image of 5n6h
STRUCTURE OF THE MEMBRANE INTEGRAL LIPOPROTEIN N-ACYLTRANSFERASE LNT FROM E. COLI
Descriptor:Apolipoprotein N-acyltransferase, (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, GLYCEROL
Authors:Huang, C.-Y., Boland, C., Howe, N., Wiktor, M., Vogeley, L., Weichert, D., Bailey, J., Olieric, V., Wang, M., Caffrey, M.
Deposit date:2017-02-15
Release date:2017-07-12
Last modified:2018-03-28
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structural insights into the mechanism of the membrane integral N-acyltransferase step in bacterial lipoprotein synthesis.
Nat Commun, 8, 2017
5N6L
  • Download 5n6l
  • View 5n6l
Molmil generated image of 5n6l
STRUCTURE OF THE MEMBRANE INTEGRAL LIPOPROTEIN N-ACYLTRANSFERASE LNT C387A MUTANT FROM E. COLI
Descriptor:Apolipoprotein N-acyltransferase, (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, GLYCEROL
Authors:Huang, C.-Y., Boland, C., Howe, N., Wiktor, M., Vogeley, L., Weichert, D., Bailey, J., Olieric, V., Wang, M., Caffrey, M.
Deposit date:2017-02-15
Release date:2017-07-12
Last modified:2018-03-28
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structural insights into the mechanism of the membrane integral N-acyltransferase step in bacterial lipoprotein synthesis.
Nat Commun, 8, 2017
5N6M
  • Download 5n6m
  • View 5n6m
Molmil generated image of 5n6m
STRUCTURE OF THE MEMBRANE INTEGRAL LIPOPROTEIN N-ACYLTRANSFERASE LNT FROM P. AERUGINOSA
Descriptor:Apolipoprotein N-acyltransferase, GLYCEROL, CITRATE ANION, ...
Authors:Huang, C.-Y., Boland, C., Howe, N., Wiktor, M., Vogeley, L., Weichert, D., Bailey, J., Olieric, V., Wang, M., Caffrey, M.
Deposit date:2017-02-15
Release date:2017-07-12
Last modified:2018-03-28
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Structural insights into the mechanism of the membrane integral N-acyltransferase step in bacterial lipoprotein synthesis.
Nat Commun, 8, 2017
5OON
  • Download 5oon
  • View 5oon
Molmil generated image of 5oon
STRUCTURE OF UNDECAPRENYL-PYROPHOSPHATE PHOSPHATASE, BACA
Descriptor:Undecaprenyl-diphosphatase, MERCURY (II) ION, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ...
Authors:Huang, C.-Y., Olieric, V., Warshamanage, R., Wang, M., Howe, N., Ghachi, M.E.I., Weichert, D., Kerff, F., Stansfeld, P., Touze, T., Caffrey, M.
Deposit date:2017-08-08
Release date:2018-03-21
Last modified:2018-06-06
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal structure of undecaprenyl-pyrophosphate phosphatase and its role in peptidoglycan biosynthesis.
Nat Commun, 9, 2018
1KVK
  • Download 1kvk
  • View 1kvk
Molmil generated image of 1kvk
THE STRUCTURE OF BINARY COMPLEX BETWEEN A MAMMALIAN MEVALONATE KINASE AND ATP: INSIGHTS INTO THE REACTION MECHANISM AND HUMAN INHERITED DISEASE
Descriptor:mevalonate kinase, MAGNESIUM ION, ADENOSINE-5'-TRIPHOSPHATE
Authors:Fu, Z., Wang, M., Potter, D., Mizioko, H.M., Kim, J.J.
Deposit date:2002-01-26
Release date:2002-03-27
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:The Structure of a Binary complex between a Mammalian Mevalonate Kinase and ATP: Insights into the Reaction Mechanism and Human Inherited Disease
J.Biol.Chem., 277, 2002
1Y0H
  • Download 1y0h
  • View 1y0h
Molmil generated image of 1y0h
STRUCTURE OF RV0793 FROM MYCOBACTERIUM TUBERCULOSIS
Descriptor:hypothetical protein Rv0793, ACETATE ION
Authors:Lemieux, M.J., Ference, C., Cherney, M.M., Wang, M., Garen, C., James, M.N., TB Structural Genomics Consortium (TBSGC)
Deposit date:2004-11-15
Release date:2004-12-28
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:The crystal structure of Rv0793, a hypothetical monooxygenase from M. tuberculosis
J.STRUCT.FUNCT.GENOM., 6, 2005
2AKJ
  • Download 2akj
  • View 2akj
Molmil generated image of 2akj
STRUCTURE OF SPINACH NITRITE REDUCTASE
Descriptor:Ferredoxin--nitrite reductase, chloroplast, IRON/SULFUR CLUSTER, ...
Authors:Swamy, U., Wang, M., Tripathy, J.N., Kim, S.-K., Hirasawa, M., Knaff, D.B., Allen, J.P.
Deposit date:2005-08-03
Release date:2006-01-24
Last modified:2018-04-04
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structure of Spinach Nitrite Reductase: Implications for Multi-electron Reactions by the Iron-Sulfur:Siroheme Cofactor
Biochemistry, 44, 2005
2P05
  • Download 2p05
  • View 2p05
Molmil generated image of 2p05
STRUCTURAL INSIGHTS INTO THE EVOLUTION OF A NON-BIOLOGICAL PROTEIN
Descriptor:a non-biological ATP binding protein 1819, ZINC ION, CHLORIDE ION, ...
Authors:Smith, M., Rosenow, M., Wang, M., Allen, J.P., Szostak, J.W., Chaput, J.C.
Deposit date:2007-02-28
Release date:2007-06-05
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural insights into the evolution of a non-biological protein: importance of surface residues in protein fold optimization.
PLoS ONE, 2, 2007
2P09
  • Download 2p09
  • View 2p09
Molmil generated image of 2p09
STRUCTURAL INSIGHTS INTO THE EVOLUTION OF A NON-BIOLOGICAL PROTEIN
Descriptor:a non-biological ATP binding protein with two mutations N32D and D65V, ZINC ION, CHLORIDE ION, ...
Authors:Smith, M., Rosenow, M., Wang, M., Allen, J.P., Szostak, J.W., Chaput, J.C.
Deposit date:2007-02-28
Release date:2007-06-05
Last modified:2018-04-04
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Structural insights into the evolution of a non-biological protein: importance of surface residues in protein fold optimization.
PLoS ONE, 2, 2007
2WFL
  • Download 2wfl
  • View 2wfl
Molmil generated image of 2wfl
CRYSTAL STRUCTURE OF POLYNEURIDINE ALDEHYDE ESTERASE
Descriptor:POLYNEURIDINE-ALDEHYDE ESTERASE, SULFATE ION
Authors:Yang, L., Hill, M., Panjikar, S., Wang, M., Stoeckigt, J.
Deposit date:2009-04-08
Release date:2009-08-18
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural Basis and Enzymatic Mechanism of the Biosynthesis of C9- from C10-Monoterpenoid Indole Alkaloids.
Angew.Chem.Int.Ed.Engl., 48, 2009
2WFM
  • Download 2wfm
  • View 2wfm
Molmil generated image of 2wfm
CRYSTAL STRUCTURE OF POLYNEURIDINE ALDEHYDE ESTERASE MUTANT (H244A)
Descriptor:POLYNEURIDINE ALDEHYDE ESTERASE
Authors:Yang, L., Hill, M., Panjikar, S., Wang, M., Stoeckigt, J.
Deposit date:2009-04-08
Release date:2010-04-21
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural Basis and Enzymatic Mechanism of the Biosynthesis of C9- from C10-Monoterpenoid Indole Alkaloids.
Angew.Chem.Int.Ed.Engl., 48, 2009
3EAD
  • Download 3ead
  • View 3ead
Molmil generated image of 3ead
CRYSTAL STRUCTURE OF CALX-CBD1
Descriptor:Na/Ca exchange protein, CALCIUM ION, GLYCEROL
Authors:Zheng, L., Wang, M.
Deposit date:2008-08-25
Release date:2009-09-08
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:crystal structure of calcium binding domain 1 from CALX
To be Published
3GZJ
  • Download 3gzj
  • View 3gzj
Molmil generated image of 3gzj
CRYSTAL STRUCTURE OF POLYNEURIDINE ALDEHYDE ESTERASE COMPLEXED WITH 16-EPI-VELLOSIMINE
Descriptor:Polyneuridine-aldehyde esterase, 16-epi-Vellosimine
Authors:Yang, L., Hill, M., Wang, M., Panjikar, S., Stoeckigt, J.
Deposit date:2009-04-07
Release date:2009-08-18
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (2.19 Å)
Cite:Structural basis and enzymatic mechanism of the biosynthesis of C9- from C10-monoterpenoid indole alkaloids
Angew.Chem.Int.Ed.Engl., 48, 2009