Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help
Search by PDB author
1D7M
DownloadVisualize
BU of 1d7m by Molmil
COILED-COIL DIMERIZATION DOMAIN FROM CORTEXILLIN I
Descriptor: CORTEXILLIN I
Authors:Burkhard, P, Kammerer, R.A, Steinmetz, M.O, Bourenkov, G.P, Aebi, U.
Deposit date:1999-10-19
Release date:2000-03-27
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:The coiled-coil trigger site of the rod domain of cortexillin I unveils a distinct network of interhelical and intrahelical salt bridges.
Structure Fold.Des., 8, 2000
7AU5
DownloadVisualize
BU of 7au5 by Molmil
Tubulin-noscapine-analogue-14e complex
Descriptor: (5~{R})-5-[(1~{S})-4,5-dimethoxy-1,3-dihydro-2-benzofuran-1-yl]-~{N}-ethyl-4-methoxy-7,8-dihydro-5~{H}-[1,3]dioxolo[4,5-g]isoquinoline-6-carboxamide, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, ...
Authors:Yong, C, Devine, S.M, Abel, A.-C, Muthiah, D, Gao, X, Callaghan, R, Capuano, B, Steinmetz, M.O, Prota, A.E, Scammels, P.J.
Deposit date:2020-11-02
Release date:2021-07-07
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:1,3-Benzodioxole-Modified Noscapine Analogues: Synthesis, Antiproliferative Activity, and Tubulin-Bound Structure.
Chemmedchem, 16, 2021
7AG9
DownloadVisualize
BU of 7ag9 by Molmil
Structure of the Kar9 protein
Descriptor: Kar9
Authors:Kumar, A, prota, A.E, Steinmetz, M.O.
Deposit date:2020-09-22
Release date:2021-07-07
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Structure of the Kar9 protein
Structure, 2021
8RIV
DownloadVisualize
BU of 8riv by Molmil
T2R-TTL-1-K08 complex
Descriptor: (4-fluoranyl-2-methyl-1~{H}-indol-5-yl) 3,4,5-trimethoxybenzenesulfonate, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, ...
Authors:Boiarska, Z, Homer, J.A, Steinmetz, M.O, Moses, J.E, Prota, A.E.P.
Deposit date:2023-12-19
Release date:2024-03-27
Method:X-RAY DIFFRACTION (2.78 Å)
Cite:Modular synthesis of functional libraries by accelerated SuFEx click chemistry.
Chem Sci, 15, 2024
8RIW
DownloadVisualize
BU of 8riw by Molmil
T2R-TTL-1-L01 complex
Descriptor: (2-methyl-1~{H}-indol-5-yl) 3,4,5-trimethoxybenzenesulfonate, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, ...
Authors:Prota, A.E.P, Boiarska, Z, Homer, J.A, Steinmetz, M.O, Moses, J.E.
Deposit date:2023-12-19
Release date:2024-03-27
Method:X-RAY DIFFRACTION (2.57 Å)
Cite:Modular synthesis of functional libraries by accelerated SuFEx click chemistry.
Chem Sci, 15, 2024
5D3A
DownloadVisualize
BU of 5d3a by Molmil
KIF21A regulatory coiled coil
Descriptor: GLYCEROL, Kinesin-like protein KIF21A
Authors:Bianchi, S, Kraatz, S, Steinmetz, M.O, Kammerer, A.R.
Deposit date:2015-08-06
Release date:2016-09-14
Method:X-RAY DIFFRACTION (2.495 Å)
Cite:Structure of KIF21A regulatory coiled coil
To Be Published
2AKF
DownloadVisualize
BU of 2akf by Molmil
Crystal structure of the coiled-coil domain of coronin 1
Descriptor: Coronin-1A, ZINC ION
Authors:Kammerer, R.A, Kostrewa, D, Progias, P, Honnappa, S, Avila, D, Lustig, A, Winkler, F.K, Pieters, J, Steinmetz, M.O.
Deposit date:2005-08-03
Release date:2005-09-27
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:A conserved trimerization motif controls the topology of short coiled coils
Proc.Natl.Acad.Sci.Usa, 102, 2005
3CO1
DownloadVisualize
BU of 3co1 by Molmil
Crystal structure of microtubule binding domain of human EB3
Descriptor: Microtubule-associated protein RP/EB family member 3
Authors:De Groot, C.O, Honnappa, S, Steinmetz, M.O.
Deposit date:2008-03-27
Release date:2009-03-17
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Mammalian end binding proteins control persistent microtubule growth.
J.Cell Biol., 2009
3E2U
DownloadVisualize
BU of 3e2u by Molmil
Crystal structure of the zink-knuckle 2 domain of human CLIP-170 in complex with CAP-Gly domain of human dynactin-1 (p150-GLUED)
Descriptor: CAP-Gly domain-containing linker protein 1, Dynactin subunit 1, ZINC ION
Authors:Weisbrich, A, Honnappa, S, Capitani, G, Steinmetz, M.O.
Deposit date:2008-08-06
Release date:2008-08-19
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structure-function relationship of CAP-Gly domains
Nat.Struct.Mol.Biol., 14, 2007
3GJP
DownloadVisualize
BU of 3gjp by Molmil
Crystal structure of mutant coiled coil GCN4 leucine zipper
Descriptor: General control protein GCN4
Authors:Honnappa, S, Steinmetz, M.O.
Deposit date:2009-03-09
Release date:2010-03-09
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2 Å)
Cite:Molecular basis of coiled-coil oligomerization-state specificity
Proc.Natl.Acad.Sci.USA, 107, 2010
3GJO
DownloadVisualize
BU of 3gjo by Molmil
Crystal structure of human EB1 in complex with microtubule Tip localization signal peptide of MACF
Descriptor: Dystonin, Microtubule-associated protein RP/EB family member 1
Authors:Honnappa, S, Steinmetz, M.O.
Deposit date:2009-03-09
Release date:2009-08-04
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:An EB1-binding motif acts as a microtubule tip localization signal
Cell(Cambridge,Mass.), 138, 2009
7PJE
DownloadVisualize
BU of 7pje by Molmil
Inhibiting parasite proliferation using a rationally designed anti-tubulin agent
Descriptor: Darpin D1, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
Authors:Sharma, A, Gaillard, N, Ehrhard, V.A, Steinmetz, M.O.
Deposit date:2021-08-24
Release date:2021-09-22
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Inhibiting parasite proliferation using a rationally designed anti-tubulin agent.
Embo Mol Med, 13, 2021
7PJF
DownloadVisualize
BU of 7pjf by Molmil
Inhibiting parasite proliferation using a rationally designed anti-tubulin agent
Descriptor: Designed ankyrin repeat protein (DARPIN) D1, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
Authors:Sharma, A, Gaillard, N, Ehrhard, V.A, Steinmetz, M.O.
Deposit date:2021-08-24
Release date:2021-09-22
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.862 Å)
Cite:Inhibiting parasite proliferation using a rationally designed anti-tubulin agent.
Embo Mol Med, 13, 2021
1WU9
DownloadVisualize
BU of 1wu9 by Molmil
Crystal structure of the C-terminal domain of the end-binding protein 1 (EB1)
Descriptor: Microtubule-associated protein RP/EB family member 1
Authors:Honnappa, S, John, C.M, Kostrewa, D, Winkler, F.K, Steinmetz, M.O.
Deposit date:2004-12-02
Release date:2005-02-01
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.54 Å)
Cite:Structural insights into the EB1-APC interaction
Embo J., 24, 2005
1Z2B
DownloadVisualize
BU of 1z2b by Molmil
Tubulin-colchicine-vinblastine: stathmin-like domain complex
Descriptor: (2ALPHA,2'BETA,3BETA,4ALPHA,5BETA)-VINCALEUKOBLASTINE, 2-MERCAPTO-N-[1,2,3,10-TETRAMETHOXY-9-OXO-5,6,7,9-TETRAHYDRO-BENZO[A]HEPTALEN-7-YL]ACETAMIDE, GUANOSINE-5'-DIPHOSPHATE, ...
Authors:Gigant, B, Wang, C, Ravelli, R.B.G, Roussi, F, Steinmetz, M.O, Curmi, P.A, Sobel, A, Knossow, M.
Deposit date:2005-03-08
Release date:2005-05-31
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (4.1 Å)
Cite:Structural basis for the regulation of tubulin by vinblastine.
Nature, 435, 2005
2L56
DownloadVisualize
BU of 2l56 by Molmil
NMR structure of the GCN4 trigger peptide refined using biased molecular dynamics simulations
Descriptor: General control protein GCN4
Authors:Missimer, J.H, Dolenc, J, Steinmetz, M.O, van Gunsteren, W.F.
Deposit date:2010-10-26
Release date:2010-12-01
Last modified:2011-10-26
Method:SOLUTION NMR
Cite:Exploring the trigger sequence of the GCN4 coiled-coil: Biased molecular dynamics resolves apparent inconsistencies in NMR measurements
Protein Sci., 19, 2010
2O7H
DownloadVisualize
BU of 2o7h by Molmil
Crystal structure of trimeric coiled coil GCN4 leucine zipper
Descriptor: General control protein GCN4
Authors:Jawhari, H, Honnappa, S, Steinmetz, M.O.
Deposit date:2006-12-11
Release date:2007-11-27
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.86 Å)
Cite:Molecular basis of coiled-coil oligomerization-state specificity
Proc.Natl.Acad.Sci.USA, 107, 2010
5FCM
DownloadVisualize
BU of 5fcm by Molmil
CrBld10-N 1-70
Descriptor: Basal body protein, ISOPROPYL ALCOHOL, SULFATE ION
Authors:Kraatz, S.H.W, Steinmetz, M.O.
Deposit date:2015-12-15
Release date:2016-07-20
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (2.229 Å)
Cite:The Human Centriolar Protein CEP135 Contains a Two-Stranded Coiled-Coil Domain Critical for Microtubule Binding.
Structure, 24, 2016
2PZI
DownloadVisualize
BU of 2pzi by Molmil
Crystal Structure of Protein kinase PknG from Mycobacterium tuberculosis in Complex with Tetrahydrobenzothiophene AX20017
Descriptor: 2-[(CYCLOPROPYLCARBONYL)AMINO]-4,5,6,7-TETRAHYDRO-1-BENZOTHIOPHENE-3-CARBOXAMIDE, CADMIUM ION, CHLORIDE ION, ...
Authors:Honnappa, S, Steinmetz, M.O.
Deposit date:2007-05-18
Release date:2007-07-24
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural basis for the specific inhibition of protein kinase G, a virulence factor of Mycobacterium tuberculosis.
Proc.Natl.Acad.Sci.Usa, 104, 2007
3TQ7
DownloadVisualize
BU of 3tq7 by Molmil
EB1c/EB3c heterodimer in complex with the CAP-Gly domain of P150glued
Descriptor: Dynactin subunit 1, Microtubule-associated protein RP/EB family member 1, Microtubule-associated protein RP/EB family member 3
Authors:De Groot, C.O, Scharer, M.A, Capitani, G, Steinmetz, M.O.
Deposit date:2011-09-09
Release date:2012-01-25
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Interaction of mammalian end binding proteins with CAP-Gly domains of CLIP-170 and p150(glued).
J.Struct.Biol., 177, 2012
1S9Z
DownloadVisualize
BU of 1s9z by Molmil
SYNTHETIC 17 AMINO ACID LONG PEPTIDE THAT FORMS A NATIVE-LIKE COILED-COIL AT AMBIENT TEMPERATURE AND AGGREGATES INTO AMYLOID-LIKE FIBRILS AT HIGHER TEMPERATURES.
Descriptor: SODIUM ION, SYNTHETIC COILED-COIL PEPTIDE, ZINC ION
Authors:Kammerer, R.A, Kostrewa, D, Zurdo, J, Detken, A, Garcia-Echeverria, C, Green, J.D, Muller, S.A, Meier, B.H, Winkler, F.K, Dobson, C.M, Steinmetz, M.O.
Deposit date:2004-02-06
Release date:2004-04-06
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.01 Å)
Cite:Exploring amyloid formation by a de novo design
Proc.Natl.Acad.Sci.USA, 101, 2004
4I4T
DownloadVisualize
BU of 4i4t by Molmil
Crystal structure of tubulin-RB3-TTL-Zampanolide complex
Descriptor: (2Z,4E)-N-[(S)-[(1S,2E,5S,8E,10Z,17S)-3,11-dimethyl-19-methylidene-7,13-dioxo-6,21-dioxabicyclo[15.3.1]henicosa-2,8,10-trien-5-yl](hydroxy)methyl]hexa-2,4-dienamide, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, ...
Authors:Prota, A.E, Steinmetz, M.O.
Deposit date:2012-11-28
Release date:2013-01-23
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Molecular Mechanism of Action of Microtubule-Stabilizing Anticancer Agents.
Science, 339, 2013
6Y6D
DownloadVisualize
BU of 6y6d by Molmil
Tubulin-7-Aminonoscapine complex
Descriptor: (3~{S})-7-azanyl-6-methoxy-3-[(5~{R})-4-methoxy-6-methyl-7,8-dihydro-5~{H}-[1,3]dioxolo[4,5-g]isoquinolin-5-yl]-3~{H}-2-benzofuran-1-one, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, ...
Authors:Oliva, M.A, Prota, A.E, Rodriguez-Salarichs, J, Gu, W, Bennani, Y.L, Jimenez-Barbero, J, Canales, A, Steinmetz, M.O, Diaz, J.F.
Deposit date:2020-02-26
Release date:2020-07-22
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural Basis of Noscapine Activation for Tubulin Binding.
J.Med.Chem., 63, 2020
6ZPH
DownloadVisualize
BU of 6zph by Molmil
Kinesin binding protein complexed with Kif15 motor domain
Descriptor: ADENOSINE-5'-DIPHOSPHATE, KIF-binding protein, Kinesin-like protein KIF15, ...
Authors:Atherton, J, Hummel, J.J.A, Olieric, N, Locke, J, Pena, A, Rosenfeld, S.S, Steinmetz, M.O, Hoogenraad, C.C, Moores, C.A.
Deposit date:2020-07-08
Release date:2020-12-30
Method:ELECTRON MICROSCOPY (6.9 Å)
Cite:The mechanism of kinesin inhibition by kinesin-binding protein.
Elife, 9, 2020
6ZWC
DownloadVisualize
BU of 6zwc by Molmil
Z-SBTub2 photoswitch bound to tubulin-DARPin D1 complex
Descriptor: 2-[2-(3,4,5-trimethoxyphenyl)ethyl]-1,3-benzothiazole, Designed Ankyrin Repeat Protein (DARPIN) D1, GUANOSINE-5'-DIPHOSPHATE, ...
Authors:Wranik, M, Weinert, T, Olieric, N, Gao, L, Kraus, Y.C.M, Bingham, R, Ntouliou, E, Ahlfeld, J, Thorn-Seshold, O, Steinmetz, M.O, Standfuss, J.
Deposit date:2020-07-28
Release date:2020-12-23
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.04 Å)
Cite:A Robust, GFP-Orthogonal Photoswitchable Inhibitor Scaffold Extends Optical Control over the Microtubule Cytoskeleton.
Cell Chem Biol, 28, 2021

218500

PDB entries from 2024-04-17

PDB statisticsPDBj update infoContact PDBjnumon