Author results

2LEF
  • Download 2lef
  • View 2lef
Molmil generated image of 2lef
LEF1 HMG DOMAIN (FROM MOUSE), COMPLEXED WITH DNA (15BP), NMR, 12 STRUCTURES
分子名称:DNA (5'-D(*CP*AP*CP*CP*CP*TP*TP*TP*GP*AP*AP*GP*CP*TP*C)-3'), DNA (5'-D(*GP*AP*GP*CP*TP*TP*CP*AP*AP*AP*GP*GP*GP*TP*G)-3'), PROTEIN (LYMPHOID ENHANCER-BINDING FACTOR)
著者Li, X., Love, J.J., Case, D.A., Wright, P.E.
登録日1998-10-13
公開日1998-10-21
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献Structural basis for DNA bending by the architectural transcription factor LEF-1.
Nature, 376, 1995
3NCZ
  • Download 3ncz
  • View 3ncz
Molmil generated image of 3ncz
X-RAY CO-STRUCTURE OF RHO-ASSOCIATED PROTEIN KINASE (ROCK1) WITH A POTENT 2H-ISOQUINOLIN-1-ONE INHIBITOR
分子名称:Rho-associated protein kinase 1, cis-4-amino-N-(7-chloro-1-oxo-1,2-dihydroisoquinolin-6-yl)cyclohexanecarboxamide
著者Li, X.
登録日2010-06-06
公開日2010-12-08
最終更新日2019-07-17
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Substituted 2H-isoquinolin-1-ones as potent Rho-kinase inhibitors: Part 2, optimization for blood pressure reduction in spontaneously hypertensive rats.
Bioorg.Med.Chem.Lett., 20, 2010
3UR1
  • Download 3ur1
  • View 3ur1
Molmil generated image of 3ur1
THE STRUCTURE OF A TERNARY COMPLEX BETWEEN CHEA DOMAINS P4 AND P5 WITH CHEW AND WITH A TRUNCATED FRAGMENT OF TM14, A CHEMORECEPTOR ANALOG FROM THERMOTOGA MARITIMA.
分子名称:Chemotaxis protein CheA, Chemotaxis protein CheW, Methyl-accepting chemotaxis protein
著者Li, X., Crane, B.R., Bilwes, A.M.
登録日2011-11-21
公開日2012-03-07
実験手法X-RAY DIFFRACTION (4.5 Å)
主引用文献The structure of native bacterial chemoreceptor arrays
Proc.Natl.Acad.Sci.USA, 2012
4TVQ
  • Download 4tvq
  • View 4tvq
Molmil generated image of 4tvq
CCM3 IN COMPLEX WITH CCM2 LD-LIKE MOTIF
分子名称:Cerebral cavernous malformations 3 protein, Cerebral cavernous malformations 2 protein
著者Li, X., Zhang, R., Fisher, O.S., Boggon, T.J.
登録日2014-06-27
公開日2015-03-25
最終更新日2017-09-20
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献CCM2-CCM3 interaction stabilizes their protein expression and permits endothelial network formation.
J.Cell Biol., 208, 2015
4YMQ
  • Download 4ymq
  • View 4ymq
Molmil generated image of 4ymq
X-RAY CO-STRUCTURE OF NUCLEAR RECEPTOR ROR-GAMMAT + SRC2 PEPTIDE WITH A BENZOTHIADIAZOLE DIOXIDE INVERSE AGONIST
分子名称:Nuclear receptor ROR-gamma, SODIUM ION, GLYCEROL, ...
著者li, X.
登録日2015-03-07
公開日2015-04-22
最終更新日2015-04-29
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Discovery of 1,3-dihydro-2,1,3-benzothiadiazole 2,2-dioxide analogs as new RORC modulators.
Bioorg.Med.Chem.Lett., 25, 2015
5T17
  • Download 5t17
  • View 5t17
Molmil generated image of 5t17
NMR STRUCTURE OF THE E. COLI PROTEIN NPR, RESIDUES 1-85
分子名称:Phosphocarrier protein NPr
著者Wang, G., Li, X., Peterkofsky, A.
登録日2016-08-18
公開日2016-09-28
最終更新日2017-09-27
実験手法SOLUTION NMR
主引用文献Solution structure of NPr, a bacterial signal-transducing protein that controls the phosphorylation state of the potassium transporter-regulating protein IIA Ntr.
Amino Acids, 35, 2008
6C9U
  • Download 6c9u
  • View 6c9u
Molmil generated image of 6c9u
CRYSTAL STRUCTURE OF [KS3][AT3] DIDOMAIN FROM MODULE 3 OF 6-DEOXYERTHRONOLIDE B SYNTHASE IN COMPLEX WITH ANTIBODY FRAGMENT (FAB)
分子名称:6-deoxyerythronolide-B synthase EryA2, modules 3 and 4, Light chain of Fab 1B2, ...
著者Deis, L.N., Li, X., Mathews, I.I., Khosla, C.
登録日2018-01-28
公開日2018-05-23
最終更新日2019-02-20
実験手法X-RAY DIFFRACTION (2.09 Å)
主引用文献Structure-Function Analysis of the Extended Conformation of a Polyketide Synthase Module.
J. Am. Chem. Soc., 140, 2018
6MLK
  • Download 6mlk
  • View 6mlk
Molmil generated image of 6mlk
STRUCTURE OF THIOESTERASE FROM DEBS WITH A THIOESTERASE-SPECIFIC ANTIBODY
分子名称:6-deoxyerythronolide-B synthase EryA3, modules 5 and 6, Light chain of Fab 3A6, ...
著者Mathews, I.I., Li, X., Khosla, C.
登録日2018-09-27
公開日2018-10-17
最終更新日2018-11-07
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献Discovery and Characterization of a Thioesterase-Specific Monoclonal Antibody That Recognizes the 6-Deoxyerythronolide B Synthase.
Biochemistry, 57, 2018
6N7P
  • Download 6n7p
  • View 6n7p
Molmil generated image of 6n7p
S. CEREVISIAE SPLICEOSOMAL E COMPLEX (UBC4)
分子名称:U1 small nuclear ribonucleoprotein 70 kDa homolog, U1 small nuclear ribonucleoprotein C, U1 small nuclear ribonucleoprotein A, ...
著者Liu, S., Li, X., Zhou, Z.H., Zhao, R.
登録日2018-11-27
公開日2019-09-18
最終更新日2019-10-02
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献A unified mechanism for intron and exon definition and back-splicing.
Nature, 573, 2019
6N7R
  • Download 6n7r
  • View 6n7r
Molmil generated image of 6n7r
SACCHAROMYCES CEREVISIAE SPLICEOSOMAL E COMPLEX (ACT1)
分子名称:U1 small nuclear ribonucleoprotein 70 kDa homolog, U1 small nuclear ribonucleoprotein C, U1 small nuclear ribonucleoprotein A, ...
著者Liu, S., Li, X., Zhou, Z.H., Zhao, R.
登録日2018-11-28
公開日2019-09-18
最終更新日2019-10-02
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献A unified mechanism for intron and exon definition and back-splicing.
Nature, 573, 2019
5Z3L
  • Download 5z3l
  • View 5z3l
Molmil generated image of 5z3l
STRUCTURE OF SNF2-NUCLEOSOME COMPLEX IN APO STATE
分子名称:Histone H3.2, Histone H4, Histone H2A, ...
著者Li, M., Xia, X., Liu, X., Li, X., Chen, Z.
登録日2018-01-08
公開日2019-04-03
実験手法ELECTRON MICROSCOPY (4.31 Å)
主引用文献Mechanism of DNA translocation underlying chromatin remodelling by Snf2.
Nature, 567, 2019
5Z3O
  • Download 5z3o
  • View 5z3o
Molmil generated image of 5z3o
STRUCTURE OF SNF2-NUCLEOSOME COMPLEX IN ADP STATE
分子名称:Histone H3.2, Histone H4, Histone H2A, ...
著者Li, M., Xia, X., Liu, X., Li, X., Chen, Z.
登録日2018-01-08
公開日2019-04-03
実験手法ELECTRON MICROSCOPY (3.62 Å)
主引用文献Mechanism of DNA translocation underlying chromatin remodelling by Snf2.
Nature, 567, 2019
5Z3U
  • Download 5z3u
  • View 5z3u
Molmil generated image of 5z3u
STRUCTURE OF SNF2-NUCLEOSOME COMPLEX AT SHL2 IN ADP BEFX STATE
分子名称:Transcription regulatory protein SNF2, Histone H3.2, Histone H4, ...
著者Li, M., Xia, X., Liu, X., Li, X., Chen, Z.
登録日2018-01-08
公開日2019-05-22
実験手法ELECTRON MICROSCOPY (4.31 Å)
主引用文献Mechanism of DNA translocation underlying chromatin remodelling by Snf2.
Nature, 567, 2019
5Z3V
  • Download 5z3v
  • View 5z3v
Molmil generated image of 5z3v
STRUCTURE OF SNF2-NUCLEOSOME COMPLEX AT SHL-2 IN ADP BEFX STATE
分子名称:Transcription regulatory protein SNF2, Histone H3.2, Histone H4, ...
著者Li, M., Xia, X., Liu, X., Li, X., Chen, Z.
登録日2018-01-08
公開日2019-05-22
実験手法ELECTRON MICROSCOPY (4.22 Å)
主引用文献Mechanism of DNA translocation underlying chromatin remodelling by Snf2.
Nature, 567, 2019
6A6B
  • Download 6a6b
  • View 6a6b
Molmil generated image of 6a6b
CRYO-EM STRUCTURE OF ALPHA-SYNUCLEIN FIBER
分子名称:Alpha-synuclein
著者Li, Y.W., Zhao, C.Y., Luo, F., Liu, Z., Gui, X., Luo, Z., Zhang, X., Li, D., Liu, C., Li, X.
登録日2018-06-27
公開日2018-07-11
最終更新日2018-10-24
実験手法ELECTRON MICROSCOPY (3.07 Å)
主引用文献Amyloid fibril structure of alpha-synuclein determined by cryo-electron microscopy
Cell Res., 28, 2018
6IY2
  • Download 6iy2
  • View 6iy2
Molmil generated image of 6iy2
STRUCTURE OF SNF2-MMTV-A NUCLEOSOME COMPLEX AT SHL2 IN ADP STATE
分子名称:Histone H3, Histone H4, Histone H2A, ...
著者Li, M., Xia, X., Liu, X., Li, X., Chen, Z.
登録日2018-12-12
公開日2019-04-03
実験手法ELECTRON MICROSCOPY (3.47 Å)
主引用文献Mechanism of DNA translocation underlying chromatin remodelling by Snf2.
Nature, 567, 2019
6IY3
  • Download 6iy3
  • View 6iy3
Molmil generated image of 6iy3
STRUCTURE OF SNF2-MMTV-A NUCLEOSOME COMPLEX AT SHL-2 IN ADP STATE
分子名称:Histone H3, Histone H4, Histone H2A, ...
著者Li, M., Xia, X., Liu, X., Li, X., Chen, Z.
登録日2018-12-12
公開日2019-04-03
実験手法ELECTRON MICROSCOPY (3.67 Å)
主引用文献Mechanism of DNA translocation underlying chromatin remodelling by Snf2.
Nature, 567, 2019
5JYY
  • Download 5jyy
  • View 5jyy
Molmil generated image of 5jyy
STRUCTURE-BASED TETRAVALENT ZANAMIVIR WITH POTENT INHIBITORY ACTIVITY AGAINST DRUG-RESISTANT INFLUENZA VIRUSES
分子名称:Neuraminidase, N-ACETYL-D-GLUCOSAMINE, BETA-D-MANNOSE, ...
著者Fu, L., Wu, Y., Bi, Y., Zhang, S., Lv, X., Qi, J., Li, Y., Lu, X., Yan, J., Gao, G.F., Li, X.
登録日2016-05-15
公開日2016-06-29
最終更新日2018-10-24
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structure-Based Tetravalent Zanamivir with Potent Inhibitory Activity against Drug-Resistant Influenza Viruses
J.Med.Chem., 59, 2016
5XSG
  • Download 5xsg
  • View 5xsg
Molmil generated image of 5xsg
ULTRAHIGH RESOLUTION STRUCTURE OF FUS (37-42) SYSGYS DETERMINED BY MICROED
分子名称:RNA-binding protein FUS
著者Luo, F., Gui, X., Zhou, H., Li, D., Li, X., Liu, C.
登録日2017-06-14
公開日2018-04-04
最終更新日2018-04-18
実験手法ELECTRON CRYSTALLOGRAPHY (0.73 Å)
主引用文献Atomic structures of FUS LC domain segments reveal bases for reversible amyloid fibril formation.
Nat. Struct. Mol. Biol., 25, 2018
4I8B
  • Download 4i8b
  • View 4i8b
Molmil generated image of 4i8b
CRYSTAL STRUCTURE OF THIOREDOXIN FROM SCHISTOSOMA JAPONICUM
分子名称:Thioredoxin
著者Wu, Q., Peng, Y., Zhao, J., Li, X., Fan, X., Zhou, X., Chen, J., Luo, Z., Shi, D.
登録日2012-12-03
公開日2013-12-04
最終更新日2015-06-17
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Expression, characterization and crystal structure of thioredoxin from Schistosoma japonicum.
Parasitology, 142, 2015
5H3O
  • Download 5h3o
  • View 5h3o
Molmil generated image of 5h3o
STRUCTURE OF A EUKARYOTIC CYCLIC NUCLEOTIDE-GATED CHANNEL
分子名称:Cyclic nucleotide-gated cation channel, CYCLIC GUANOSINE MONOPHOSPHATE, SODIUM ION
著者Li, M., Zhou, X., Wang, S., Michailidis, I., Gong, Y., Su, D., Li, H., Li, X., Yang, J.
登録日2016-10-26
公開日2017-01-25
最終更新日2017-12-13
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Structure of a eukaryotic cyclic-nucleotide-gated channel.
Nature, 542, 2017
5TJA
  • Download 5tja
  • View 5tja
Molmil generated image of 5tja
I-II LINKER OF TRPML1 CHANNEL AT PH 6
分子名称:Mucolipin-1
著者Li, M., Zhang, W.K., Benvin, N.M., Zhou, X., Su, D., Li, H., Wang, S., Michailidis, I.E., Tong, L., Li, X., Yang, J.
登録日2016-10-04
公開日2017-01-25
最終更新日2017-09-27
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural basis of dual Ca(2+)/pH regulation of the endolysosomal TRPML1 channel.
Nat. Struct. Mol. Biol., 24, 2017
5TJB
  • Download 5tjb
  • View 5tjb
Molmil generated image of 5tjb
I-II LINKER OF TRPML1 CHANNEL AT PH 4.5
分子名称:Mucolipin-1
著者Li, M., Zhang, W.K., Benvin, N.M., Zhou, X., Su, D., Li, H., Wang, S., Michailidis, I.E., Tong, L., Li, X., Yang, J.
登録日2016-10-04
公開日2017-01-25
最終更新日2017-09-27
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structural basis of dual Ca(2+)/pH regulation of the endolysosomal TRPML1 channel.
Nat. Struct. Mol. Biol., 24, 2017
5TJC
  • Download 5tjc
  • View 5tjc
Molmil generated image of 5tjc
I-II LINKER OF TRPML1 CHANNEL AT PH 7.5
分子名称:Mucolipin-1
著者Li, M., Zhang, W.K., Benvin, N.M., Zhou, X., Su, D., Li, H., Wang, S., Michailidis, I.E., Tong, L., Li, X., Yang, J.
登録日2016-10-04
公開日2017-01-25
最終更新日2017-09-27
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structural basis of dual Ca(2+)/pH regulation of the endolysosomal TRPML1 channel.
Nat. Struct. Mol. Biol., 24, 2017
5X0X
  • Download 5x0x
  • View 5x0x
Molmil generated image of 5x0x
COMPLEX OF SNF2-NUCLEOSOME COMPLEX WITH SNF2 BOUND TO POSITION +6 OF THE NUCLEOSOME
分子名称:Histone H3.2, Histone H4, Histone H2A, ...
著者Li, M., Liu, X., Xia, X., Chen, Z., Li, X.
登録日2017-01-23
公開日2017-04-19
最終更新日2019-10-09
実験手法ELECTRON MICROSCOPY (3.97 Å)
主引用文献Mechanism of chromatin remodelling revealed by the Snf2-nucleosome structure.
Nature, 544, 2017