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3WSA
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THE TUBERCULOSIS DRUG SQ109 INHIBITS TRYPANOSOMA CRUZI CELL PROLIFERATION AND ACTS SYNERGISTICALLY WITH POSACONAZOLE
分子名称:Squalene synthase, N-[(2Z)-3,7-dimethylocta-2,6-dien-1-yl]-N'-[(1R,3S,5R,7R)-tricyclo[3.3.1.1~3,7~]dec-2-yl]ethane-1,2-diamine
著者Shang, N., Li, Q., Huang, C.H., Oldfield, E., Guo, R.T.
登録日2014-03-05
公開日2015-04-01
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献The Tuberculosis Drug SQ109 Inhibits Trypanosoma cruzi Cell Proliferation and acts Synergistically with Posaconazole
To be Published
3WSB
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THE TUBERCULOSIS DRUG SQ109 INHIBITS TRYPANOSOMA CRUZI CELL PROLIFERATION AND ACTS SYNERGISTICALLY WITH POSACONAZOLE
分子名称:Farnesyltransferase, putative, S-[(2E,6E)-3,7,11-TRIMETHYLDODECA-2,6,10-TRIENYL] TRIHYDROGEN THIODIPHOSPHATE, ...
著者Shang, N., Li, Q., Huang, C.H., Oldfield, E., Guo, R.T.
登録日2014-03-05
公開日2015-04-01
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献The Tuberculosis Drug SQ109 Inhibits Trypanosoma cruzi Cell Proliferation and acts Synergistically with Posaconazole
To be Published
4AYT
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STRUCTURE OF THE HUMAN MITOCHONDRIAL ABC TRANSPORTER, ABCB10
分子名称:ATP-BINDING CASSETTE SUB-FAMILY B MEMBER 10 MITOCHONDRIAL, GLYCINE, MAGNESIUM ION, ...
著者Pike, A.C.W., Shintre, C.A., Li, Q., Kim, J., von Delft, F., Barr, A.J., Das, S., Chaikuad, A., Xia, X., Quigley, A., Dong, Y., Dong, L., Krojer, T., Vollmar, M., Muniz, J.R.C., Bray, J.E., Berridge, G., Chalk, R., Gileadi, O., Burgess-Brown, N., Shrestha, L., Goubin, S., Yang, J., Mahajan, P., Mukhopadhyay, S., Bullock, A.N., Arrowsmith, C.H., Weigelt, J., Bountra, C., Edwards, A.M., Carpenter, E.P.
登録日2012-06-22
公開日2012-07-11
最終更新日2018-01-24
実験手法X-RAY DIFFRACTION (2.85 Å)
主引用文献Structures of Abcb10, a Human ATP-Binding Cassette Transporter in Apo- and Nucleotide-Bound States
Proc.Natl.Acad.Sci.USA, 110, 2013
4AYW
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STRUCTURE OF THE HUMAN MITOCHONDRIAL ABC TRANSPORTER, ABCB10 (PLATE FORM)
分子名称:ATP-BINDING CASSETTE SUB-FAMILY B MEMBER 10, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, DODECYL-BETA-D-MALTOSIDE, ...
著者Pike, A.C.W., Shintre, C.A., Li, Q., Kim, J., von Delft, F., Barr, A.J., Das, S., Chaikuad, A., Xia, X., Quigley, A., Dong, Y., Dong, L., Krojer, T., Vollmar, M., Muniz, J.R.C., Bray, J.E., Berridge, G., Chalk, R., Gileadi, O., Burgess-Brown, N., Shrestha, L., Goubin, S., Yang, J., Mahajan, P., Mukhopadhyay, S., Bullock, A.N., Arrowsmith, C.H., Weigelt, J., Bountra, C., Edwards, A.M., Carpenter, E.P.
登録日2012-06-22
公開日2012-07-11
最終更新日2018-01-24
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Structures of Abcb10, a Human ATP-Binding Cassette Transporter in Apo- and Nucleotide-Bound States
Proc.Natl.Acad.Sci.USA, 110, 2013
4AYX
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STRUCTURE OF THE HUMAN MITOCHONDRIAL ABC TRANSPORTER, ABCB10 (ROD FORM B)
分子名称:ATP-BINDING CASSETTE SUB-FAMILY B MEMBER 10, GLYCINE, MAGNESIUM ION, ...
著者Pike, A.C.W., Shintre, C.A., Li, Q., Kim, J., von Delft, F., Barr, A.J., Das, S., Chaikuad, A., Xia, X., Quigley, A., Dong, Y., Dong, L., Krojer, T., Vollmar, M., Muniz, J.R.C., Bray, J.E., Berridge, G., Chalk, R., Gileadi, O., Burgess-Brown, N., Shrestha, L., Goubin, S., Yang, J., Mahajan, P., Mukhopadhyay, S., Bullock, A.N., Arrowsmith, C.H., Weigelt, J., Bountra, C., Edwards, A.M., Carpenter, E.P.
登録日2012-06-22
公開日2012-07-11
最終更新日2018-01-24
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Structures of Abcb10, a Human ATP-Binding Cassette Transporter in Apo- and Nucleotide-Bound States
Proc.Natl.Acad.Sci.USA, 110, 2013
4E8C
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CRYSTAL STRUCTURE OF STREPTOCOCCAL BETA-GALACTOSIDASE IN COMPLEX WITH GALACTOSE
分子名称:Glycosyl hydrolase, family 35, BETA-D-GALACTOSE, ...
著者Cheng, W., Wang, L., Bai, X.H., Jiang, Y.L., Li, Q., Yu, G., Zhou, C.Z., Chen, Y.X.
登録日2012-03-20
公開日2012-05-30
最終更新日2013-08-07
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Structural insights into the substrate specificity of Streptococcus pneumoniae beta (1,3)-galactosidase BgaC
J.Biol.Chem., 287, 2012
4E8D
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CRYSTAL STRUCTURE OF STREPTOCOCCAL BETA-GALACTOSIDASE
分子名称:Glycosyl hydrolase, family 35, GLYCEROL
著者Cheng, W., Wang, L., Bai, X.H., Jiang, Y.L., Li, Q., Yu, G., Zhou, C.Z., Chen, Y.X.
登録日2012-03-20
公開日2012-05-30
最終更新日2013-08-07
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structural insights into the substrate specificity of Streptococcus pneumoniae beta (1,3)-galactosidase BgaC
J.Biol.Chem., 287, 2012
4GA7
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CRYSTAL STRUCTURE OF HUMAN SERPINB1 MUTANT
分子名称:Leukocyte elastase inhibitor
著者Wang, L., Li, Q., Wu, L., Zhang, K., Tong, L., Sun, F., Fan, Z.
登録日2012-07-25
公開日2013-01-16
最終更新日2013-07-17
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Identification of SERPINB1 as a physiological inhibitor of human granzyme H
J.Immunol., 190, 2013
4GAW
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CRYSTAL STRUCTURE OF ACTIVE HUMAN GRANZYME H
分子名称:Granzyme H, SULFATE ION, CHLORIDE ION
著者Wang, L., Li, Q., Wu, L., Zhang, K., Tong, L., Sun, F., Fan, Z.
登録日2012-07-25
公開日2013-01-16
最終更新日2013-07-17
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Identification of SERPINB1 as a physiological inhibitor of human granzyme H
J.Immunol., 190, 2013
4HMO
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CRYSTAL STRUCTURE OF STREPTOCOCCUS PNEUMONIAE TIGR4 PIAA IN COMPLEX WITH BIS-TRIS PROPANE
分子名称:Iron-compound ABC transporter, iron compound-binding protein, GLYCEROL, ...
著者Cheng, W., Li, Q., Jiang, Y.-L., Chen, Y., Zhou, C.-Z.
登録日2012-10-18
公開日2013-09-04
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structures of Streptococcus pneumoniae PiaA and Its Complex with Ferrichrome Reveal Insights into the Substrate Binding and Release of High Affinity Iron Transporters
Plos One, 8, 2013
4HMP
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CRYSTAL STRUCTURE OF IRON UPTAKE ABC TRANSPORTER SUBSTRATE-BINDING PROTEIN PIAA FROM STREPTOCOCCUS PNEUMONIAE TIGR4
分子名称:Iron-compound ABC transporter, iron compound-binding protein, CADMIUM ION, ...
著者Cheng, W., Li, Q., Jiang, Y.-L., Chen, Y., Zhou, C.-Z.
登録日2012-10-18
公開日2013-09-04
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structures of Streptococcus pneumoniae PiaA and Its Complex with Ferrichrome Reveal Insights into the Substrate Binding and Release of High Affinity Iron Transporters
Plos One, 8, 2013
4HMQ
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CRYSTAL STRUCTURE OF STREPTOCOCCUS PNEUMONIAE TIGR4 PIAA IN COMPLEX WITH FERRICHROME
分子名称:Iron-compound ABC transporter, iron compound-binding protein, FERRICHROME, ...
著者Cheng, W., Li, Q., Jiang, Y.-L., Chen, Y., Zhou, C.-Z.
登録日2012-10-18
公開日2013-09-04
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structures of Streptococcus pneumoniae PiaA and Its Complex with Ferrichrome Reveal Insights into the Substrate Binding and Release of High Affinity Iron Transporters
Plos One, 8, 2013
4JTV
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CRYSTAL STRUCTURE OF 2009 PANDEMIC INFLUENZA VIRUS HEMAGGLUTININ COMPLEXED WITH HUMAN RECEPTOR ANALOGUE LSTC
分子名称:Hemagglutinin, N-ACETYL-D-GLUCOSAMINE, O-SIALIC ACID, ...
著者Zhang, W., Shi, Y., Qi, J., Gao, F., Li, Q., Fan, Z., Yan, J., Gao, G.F.
登録日2013-03-24
公開日2013-05-01
最終更新日2013-08-07
実験手法X-RAY DIFFRACTION (2.997 Å)
主引用文献Molecular basis of the receptor binding specificity switch of the hemagglutinins from both the 1918 and 2009 pandemic influenza A viruses by a D225G substitution
J.Virol., 87, 2013
4JTX
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CRYSTAL STRUCTURE OF 2009 PANDEMIC INFLUENZA VIRUS HEMAGGLUTININ MUTANT D225E
分子名称:Hemagglutinin, N-ACETYL-D-GLUCOSAMINE
著者Zhang, W., Shi, Y., Qi, J., Gao, F., Li, Q., Fan, Z., Yan, J., Gao, G.F.
登録日2013-03-24
公開日2013-05-01
最終更新日2013-08-07
実験手法X-RAY DIFFRACTION (2.997 Å)
主引用文献Molecular basis of the receptor binding specificity switch of the hemagglutinins from both the 1918 and 2009 pandemic influenza A viruses by a D225G substitution
J.Virol., 87, 2013
4JU0
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CRYSTAL STRUCTURE OF 2009 PANDEMIC INFLUENZA VIRUS HEMAGGLUTININ MUTANT D225E COMPLEXED WITH HUMAN RECEPTOR ANALOGUE LSTC
分子名称:Hemagglutinin, O-SIALIC ACID, BETA-D-GALACTOSE, ...
著者Zhang, W., Shi, Y., Qi, J., Gao, F., Li, Q., Fan, Z., Yan, J., Gao, G.F.
登録日2013-03-24
公開日2013-05-01
最終更新日2013-08-07
実験手法X-RAY DIFFRACTION (2.908 Å)
主引用文献Molecular basis of the receptor binding specificity switch of the hemagglutinins from both the 1918 and 2009 pandemic influenza A viruses by a D225G substitution
J.Virol., 87, 2013
4JUG
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CRYSTAL STRUCTURE OF 1918 PANDEMIC INFLUENZA VIRUS HEMAGGLUTININ MUTANT D225G
分子名称:Hemagglutinin, N-ACETYL-D-GLUCOSAMINE, BETA-D-MANNOSE
著者Zhang, W., Shi, Y., Qi, J., Gao, F., Li, Q., Fan, Z., Yan, J., Gao, G.F.
登録日2013-03-24
公開日2013-05-01
最終更新日2013-08-07
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Molecular basis of the receptor binding specificity switch of the hemagglutinins from both the 1918 and 2009 pandemic influenza A viruses by a D225G substitution
J.Virol., 87, 2013
4JUH
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CRYSTAL STRUCTURE OF 1918 PANDEMIC INFLUENZA VIRUS HEMAGGLUTININ MUTANT D225G COMPLEXED WITH AVIAN RECEPTOR ANALOGUE LSTA
分子名称:Hemagglutinin, N-ACETYL-D-GLUCOSAMINE, O-SIALIC ACID, ...
著者Zhang, W., Shi, Y., Qi, J., Gao, F., Li, Q., Fan, Z., Yan, J., Gao, G.F.
登録日2013-03-24
公開日2013-05-01
最終更新日2013-08-07
実験手法X-RAY DIFFRACTION (2.805 Å)
主引用文献Molecular basis of the receptor binding specificity switch of the hemagglutinins from both the 1918 and 2009 pandemic influenza A viruses by a D225G substitution
J.Virol., 87, 2013
4JUJ
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CRYSTAL STRUCTURE OF 1918 PANDEMIC INFLUENZA VIRUS HEMAGGLUTININ MUTNAT D225G COMPLEXED WITH HUMAN RECEPTOR ANALOGUE LSTC
分子名称:Hemagglutinin, N-ACETYL-D-GLUCOSAMINE, O-SIALIC ACID, ...
著者Zhang, W., Shi, Y., Qi, J., Gao, F., Li, Q., Fan, Z., Yan, J., Gao, G.F.
登録日2013-03-25
公開日2013-05-01
最終更新日2013-08-07
実験手法X-RAY DIFFRACTION (3.013 Å)
主引用文献Molecular basis of the receptor binding specificity switch of the hemagglutinins from both the 1918 and 2009 pandemic influenza A viruses by a D225G substitution
J.Virol., 87, 2013
4M57
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CRYSTAL STRUCTURE OF THE PENTATRICOPEPTIDE REPEAT PROTEIN PPR10 FROM MAIZE
分子名称:Chloroplast pentatricopeptide repeat protein 10
著者Yin, P., Li, Q., Yan, C., Liu, Y., Yan, N.
登録日2013-08-08
公開日2013-10-30
最終更新日2013-12-18
実験手法X-RAY DIFFRACTION (2.86 Å)
主引用文献Structural basis for the modular recognition of single-stranded RNA by PPR proteins.
Nature, 504, 2013
4M59
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CRYSTAL STRUCTURE OF THE PENTATRICOPEPTIDE REPEAT PROTEIN PPR10 IN COMPLEX WITH AN 18-NT PSAJ RNA ELEMENT
分子名称:Chloroplast pentatricopeptide repeat protein 10, psaJ RNA, PHOSPHATE ION
著者Yin, P., Li, Q., Yan, C., Liu, Y., Yan, N.
登録日2013-08-08
公開日2013-10-30
最終更新日2013-12-18
実験手法X-RAY DIFFRACTION (2.46 Å)
主引用文献Structural basis for the modular recognition of single-stranded RNA by PPR proteins.
Nature, 504, 2013
4Q2W
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CRYSTAL STRUCTURE OF PNEUMOCOCCAL PEPTIDOGLYCAN HYDROLASE LYTB
分子名称:Putative endo-beta-N-acetylglucosaminidase, GLYCEROL
著者Bai, X.H., Chen, H.J., Jiang, Y.L., Wen, Z., Cheng, W., Li, Q., Zhang, J.R., Chen, Y., Zhou, C.Z.
登録日2014-04-10
公開日2014-07-16
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Structure of pneumococcal peptidoglycan hydrolase LytB reveals insights into the bacterial cell wall remodeling and pathogenesis
J.Biol.Chem., 2014
4QN3
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CRYSTAL STRUCTURE OF NEURAMINIDASE N7
分子名称:Neuraminidase, CALCIUM ION, N-ACETYL-D-GLUCOSAMINE, ...
著者Sun, X., Li, Q., Wu, Y., Liu, Y., Qi, J., Vavricka, C.J., Gao, G.F.
登録日2014-06-17
公開日2014-07-30
実験手法X-RAY DIFFRACTION (2.092 Å)
主引用文献Structure of influenza virus N7: the last piece of the neuraminidase "jigsaw" puzzle
J.Virol., 2014
4QN4
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CRYSTAL STRUCTURE OF NEURAMINIDASE N6
分子名称:Neuraminidase, CALCIUM ION, N-ACETYL-D-GLUCOSAMINE, ...
著者Sun, X., Li, Q., Wu, Y., Liu, Y., Qi, J., Vavricka, C.J., Gao, G.F.
登録日2014-06-17
公開日2014-07-30
最終更新日2014-08-06
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structure of influenza virus N7: the last piece of the neuraminidase "jigsaw" puzzle
J.Virol., 2014
4QN5
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NEURAMINIDASE N5 BINDS LSTA AT THE SECOND SIA BINDING SITE
分子名称:Neuraminidase, CALCIUM ION, N-ACETYL-D-GLUCOSAMINE, ...
著者Sun, X., Li, Q., Wu, Y., Liu, Y., Qi, J., Vavricka, C.J., Gao, G.F.
登録日2014-06-17
公開日2014-07-30
最終更新日2014-08-06
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structure of influenza virus N7: the last piece of the neuraminidase "jigsaw" puzzle
J.Virol., 2014
4QN6
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CRYSTAL STRUCTURE OF NEURAMINIDASE N6 COMPLEXED WITH LANINAMIVIR
分子名称:Neuraminidase, CALCIUM ION, N-ACETYL-D-GLUCOSAMINE, ...
著者Sun, X., Li, Q., Wu, Y., Liu, Y., Qi, J., Vavricka, C.J., Gao, G.F.
登録日2014-06-17
公開日2014-07-30
最終更新日2014-08-06
実験手法X-RAY DIFFRACTION (1.945 Å)
主引用文献Structure of influenza virus N7: the last piece of the neuraminidase "jigsaw" puzzle
J.Virol., 2014