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4RLJ
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CRYSTAL STRUCTURE OF (3R)-HYDROXYACYL-ACP DEHYDRATASE HADAB HETERO-DIMER FROM MYCOBACTERIUM TUBERCULOSIS
Descriptor:(3R)-hydroxyacyl-ACP dehydratase subunit HadA, (3R)-hydroxyacyl-ACP dehydratase subunit HadB, GLYCEROL, ...
Authors:Li, J., Dong, Y., Rao, Z.H.
Deposit date:2014-10-17
Release date:2015-10-21
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Molecular basis for the inhibition of beta-hydroxyacyl-ACP dehydratase HadAB complex from Mycobacterium tuberculosis by flavonoid inhibitors.
Protein Cell, 6, 2015
4RLT
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CRYSTAL STRUCTURE OF (3R)-HYDROXYACYL-ACP DEHYDRATASE HADAB HETERO-DIMER FROM MYCOBACTERIUM TUBERCULOSIS COMPLEXED WITH FISETIN
Descriptor:(3R)-hydroxyacyl-ACP dehydratase subunit HadA, (3R)-hydroxyacyl-ACP dehydratase subunit HadB, 3,7,3',4'-TETRAHYDROXYFLAVONE, ...
Authors:Li, J., Dong, Y., Rao, Z.H.
Deposit date:2014-10-18
Release date:2015-10-21
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (2.049 Å)
Cite:Molecular basis for the inhibition of beta-hydroxyacyl-ACP dehydratase HadAB complex from Mycobacterium tuberculosis by flavonoid inhibitors.
Protein Cell, 6, 2015
4RLU
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CRYSTAL STRUCTURE OF (3R)-HYDROXYACYL-ACP DEHYDRATASE HADAB HETERO-DIMER FROM MYCOBACTERIUM TUBERCULOSIS COMPLEXED WITH 2',4,4'-TRIHYDROXYCHALCONE
Descriptor:(3R)-hydroxyacyl-ACP dehydratase subunit HadA, (3R)-hydroxyacyl-ACP dehydratase subunit HadB, 2',4,4'-TRIHYDROXYCHALCONE, ...
Authors:Li, J., Dong, Y., Rao, Z.H.
Deposit date:2014-10-18
Release date:2015-10-21
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (2.198 Å)
Cite:Molecular basis for the inhibition of beta-hydroxyacyl-ACP dehydratase HadAB complex from Mycobacterium tuberculosis by flavonoid inhibitors.
Protein Cell, 6, 2015
4RLW
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CRYSTAL STRUCTURE OF (3R)-HYDROXYACYL-ACP DEHYDRATASE HADAB HETERO-DIMER FROM MYCOBACTERIUM TUBERCULOSIS COMPLEXED WITH BUTEIN
Descriptor:(3R)-hydroxyacyl-ACP dehydratase subunit HadA, (3R)-hydroxyacyl-ACP dehydratase subunit HadB, (2E)-1-(2,4-dihydroxyphenyl)-3-(3,4-dihydroxyphenyl)prop-2-en-1-one, ...
Authors:Li, J., Dong, Y., Rao, Z.H.
Deposit date:2014-10-18
Release date:2015-10-21
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (2.196 Å)
Cite:Molecular basis for the inhibition of beta-hydroxyacyl-ACP dehydratase HadAB complex from Mycobacterium tuberculosis by flavonoid inhibitors.
Protein Cell, 6, 2015
5ZCK
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STRUCTURE OF THE RIP3 CORE REGION
Descriptor:peptide from Receptor-interacting serine/threonine-protein kinase 3, SODIUM ION
Authors:Li, J., Wu, H.
Deposit date:2018-02-18
Release date:2018-04-18
Last modified:2018-05-30
Method:X-RAY DIFFRACTION (1.271 Å)
Cite:The Structure of the Necrosome RIPK1-RIPK3 Core, a Human Hetero-Amyloid Signaling Complex.
Cell, 173, 2018
1DLC
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CRYSTAL STRUCTURE OF INSECTICIDAL DELTA-ENDOTOXIN FROM BACILLUS THURINGIENSIS AT 2.5 ANGSTROMS RESOLUTION
Descriptor:DELTA-ENDOTOXIN CRYIIIA
Authors:Li, J.
Deposit date:1994-06-22
Release date:1994-09-30
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structure of insecticidal delta-endotoxin from Bacillus thuringiensis at 2.5 A resolution.
Nature, 353, 1991
3MP1
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COMPLEX STRUCTURE OF SGF29 AND TRIMETHYLATED H3K4
Descriptor:Maltose-binding periplasmic protein,LINKER,SAGA-associated factor 29, H3K4me3 peptide, MALTOSE, ...
Authors:Li, J., Ruan, J., Wu, M., Xue, X., Zang, J.
Deposit date:2010-04-24
Release date:2011-05-04
Last modified:2017-06-21
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Sgf29 binds histone H3K4me2/3 and is required for SAGA complex recruitment and histone H3 acetylation
Embo J., 30, 2011
3MP6
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COMPLEX STRUCTURE OF SGF29 AND DIMETHYLATED H3K4
Descriptor:Maltose-binding periplasmic protein,LINKER,SAGA-associated factor 29, H3K4me2 peptide, MALTOSE
Authors:Li, J., Wu, M., Ruan, J., Zang, J.
Deposit date:2010-04-25
Release date:2011-05-04
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (1.48 Å)
Cite:Sgf29 binds histone H3K4me2/3 and is required for SAGA complex recruitment and histone H3 acetylation
Embo J., 30, 2011
3MP8
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CRYSTAL STRUCTURE OF SGF29 TUDOR DOMAIN
Descriptor:Maltose-binding periplasmic protein,LINKER,SAGA-associated factor 29, MALTOSE, GLYCEROL, ...
Authors:Li, J., Wu, M., Ruan, J., Zang, J.
Deposit date:2010-04-26
Release date:2011-05-04
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (1.92 Å)
Cite:Sgf29 binds histone H3K4me2/3 and is required for SAGA complex recruitment and histone H3 acetylation
Embo J., 30, 2011
4BBE
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AMINOALKYLPYRIMIDINE INHIBITOR COMPLEXES WITH JAK2
Descriptor:TYROSINE-PROTEIN KINASE JAK2, N-[4-[2-[(4-morpholin-4-ylphenyl)amino]pyrimidin-4-yl]phenyl]ethanamide
Authors:Li, J.
Deposit date:2012-09-21
Release date:2012-11-21
Last modified:2012-12-19
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Sar and in Vivo Evaluation of 4-Aryl-2-Aminoalkylpyrimidines as Potent and Selective Janus Kinase 2 (Jak2) Inhibitors
Bioorg.Med.Chem.Lett., 22, 2012
4BBF
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AMINOALKYLPYRIMIDINE INHIBITOR COMPLEXES WITH JAK2
Descriptor:TYROSINE-PROTEIN KINASE JAK2, (2R)-N-[4-[2-[(4-morpholin-4-ylphenyl)amino]pyrimidin-4-yl]phenyl]pyrrolidine-2-carboxamide
Authors:Li, J.
Deposit date:2012-09-21
Release date:2012-11-21
Last modified:2017-06-28
Method:X-RAY DIFFRACTION (2 Å)
Cite:Sar and in Vivo Evaluation of 4-Aryl-2-Aminoalkylpyrimidines as Potent and Selective Janus Kinase 2 (Jak2) Inhibitors
Bioorg.Med.Chem.Lett., 22, 2012
4LWE
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CRYSTAL STRUCTURE OF THE HUMAN HSP90-ALPHA N-DOMAIN BOUND TO THE HSP90 INHIBITOR FJ2
Descriptor:Heat shock protein HSP 90-alpha, N-[3-(5-chloro-2,4-dihydroxyphenyl)-4-(4-methoxyphenyl)-1,2-oxazol-5-yl]acetamide
Authors:Li, J., Shi, F., Xiong, B., He, J.
Deposit date:2013-07-27
Release date:2014-07-30
Last modified:2016-10-12
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Discovery of potent N-(isoxazol-5-yl)amides as HSP90 inhibitors.
Eur.J.Med.Chem., 87, 2014
4LWF
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CRYSTAL STRUCTURE OF THE HUMAN HSP90-ALPHA N-DOMAIN BOUND TO THE HSP90 INHIBITOR FJ3
Descriptor:Heat shock protein HSP 90-alpha, 4-(5-amino-1,2-oxazol-3-yl)-6-(propan-2-yl)benzene-1,3-diol
Authors:Li, J., Shi, F., Xiong, B., He, J.
Deposit date:2013-07-27
Release date:2014-07-30
Last modified:2016-10-12
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Discovery of potent N-(isoxazol-5-yl)amides as HSP90 inhibitors.
Eur.J.Med.Chem., 87, 2014
4LWG
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CRYSTAL STRUCTURE OF THE HUMAN HSP90-ALPHA N-DOMAIN BOUND TO THE HSP90 INHIBITOR FJ4
Descriptor:Heat shock protein HSP 90-alpha, 1-(5-chloro-2,4-dihydroxyphenyl)-2-(4-methoxyphenyl)ethanone
Authors:Li, J., Shi, F., Xiong, B., He, J.
Deposit date:2013-07-27
Release date:2014-07-30
Last modified:2016-10-12
Method:X-RAY DIFFRACTION (1.599 Å)
Cite:Discovery of potent N-(isoxazol-5-yl)amides as HSP90 inhibitors.
Eur.J.Med.Chem., 87, 2014
4LWH
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CRYSTAL STRUCTURE OF THE HUMAN HSP90-ALPHA N-DOMAIN BOUND TO THE HSP90 INHIBITOR FJ5
Descriptor:Heat shock protein HSP 90-alpha, N-{3-[2,4-dihydroxy-5-(propan-2-yl)phenyl]-4-[4-(morpholin-4-ylmethyl)phenyl]-1,2-oxazol-5-yl}cyclopropanecarboxamide
Authors:Li, J., Shi, F., Xiong, B., He, J.
Deposit date:2013-07-27
Release date:2014-07-30
Last modified:2016-10-12
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Discovery of potent N-(isoxazol-5-yl)amides as HSP90 inhibitors.
Eur.J.Med.Chem., 87, 2014
4LWI
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CRYSTAL STRUCTURE OF THE HUMAN HSP90-ALPHA N-DOMAIN BOUND TO THE HSP90 INHIBITOR FJ6
Descriptor:Heat shock protein HSP 90-alpha, N-{3-[2,4-dihydroxy-5-(propan-2-yl)phenyl]-4-(4-methoxyphenyl)-1,2-oxazol-5-yl}cyclopropanecarboxamide
Authors:Li, J., Shi, F., Xiong, B., He, J.
Deposit date:2013-07-27
Release date:2014-07-30
Last modified:2016-10-12
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Discovery of potent N-(isoxazol-5-yl)amides as HSP90 inhibitors.
Eur.J.Med.Chem., 87, 2014
4R3M
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CRYSTAL STRUCTURE OF HUMAN HSP90 WITH JR9
Descriptor:Heat shock protein HSP 90-alpha, N~3~-benzyl-2-[(6-bromo-1,3-benzodioxol-5-yl)methyl]imidazo[1,2-a]pyrazine-3,8-diamine
Authors:Li, J., Yang, M., Ren, J., Xiong, B., He, J.
Deposit date:2014-08-16
Release date:2014-11-05
Last modified:2015-11-25
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Multi-substituted 8-aminoimidazo[1,2-a]pyrazines by Groebke-Blackburn-Bienayme reaction and their Hsp90 inhibitory activity.
Org.Biomol.Chem., 13, 2015
5HC0
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STRUCTURE OF ESTERASE EST22 WITH P-NITROPHENOL
Descriptor:Lipolytic enzyme, GLYCEROL, P-NITROPHENOL, ...
Authors:Li, J., Huang, J.
Deposit date:2016-01-04
Release date:2017-01-18
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Structural insights of a hormone sensitive lipase homologue Est22.
Sci Rep, 6, 2016
5HC2
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STRUCTURE OF ESTERASE EST22 MUTANT-S188A WITH P-NITROPHENOL
Descriptor:Lipolytic enzyme, P-NITROPHENOL, IMIDAZOLE
Authors:Li, J., Huang, J.
Deposit date:2016-01-04
Release date:2017-01-18
Method:X-RAY DIFFRACTION (1.986 Å)
Cite:Structural insights of a hormone sensitive lipase homologue Est22.
Sci Rep, 6, 2016
5HC3
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THE STRUCTURE OF ESTERASE EST22
Descriptor:Lipolytic enzyme, GLYCEROL
Authors:Li, J., Huang, J.
Deposit date:2016-01-04
Release date:2017-01-18
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural insights of a hormone sensitive lipase homologue Est22.
Sci Rep, 6, 2016
5HC4
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STRUCTURE OF ESTERASE EST22
Descriptor:Lipolytic enzyme, GLYCEROL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL
Authors:Li, J., Huang, J.
Deposit date:2016-01-04
Release date:2017-01-18
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural insights of a hormone sensitive lipase homologue Est22.
Sci Rep, 6, 2016
5HC5
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THE STRUCTURE OF ESTERASE EST22 MUTANT-S188A
Descriptor:Lipolytic enzyme
Authors:Li, J., Huang, J.
Deposit date:2016-01-04
Release date:2017-01-18
Method:X-RAY DIFFRACTION (2.43 Å)
Cite:Structural insights of a hormone sensitive lipase homologue Est22.
Sci Rep, 6, 2016
6JLS
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CRYSTAL STRUCTURE OF FMN-DEPENDENT CYSTEINE DECARBOXYLASES TVAF FROM THIOVIRIDAMIDE BIOSYNTHESIS
Descriptor:Putative flavoprotein decarboxylase, FLAVIN MONONUCLEOTIDE
Authors:Li, J., Lu, J., Wang, H., Zhu, J.
Deposit date:2019-03-06
Release date:2019-06-26
Last modified:2019-07-10
Method:X-RAY DIFFRACTION (2.24 Å)
Cite:Characterization of the FMN-Dependent Cysteine Decarboxylase from Thioviridamide Biosynthesis.
Org.Lett., 21, 2019
2FJ3
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NMR SOLUTION OF RABBIT PRION PROTEIN (91-228)
Descriptor:Major prion protein
Authors:Li, J., Lin, D.H.
Deposit date:2005-12-31
Release date:2006-12-31
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Unique structural characteristics of the rabbit prion protein
J.Biol.Chem., 285, 2010
2JOM
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NMR STRUCTURE OF RABBIT PRION PROTEIN MUTATION I214V
Descriptor:Major prion protein
Authors:Li, J., Lin, D.
Deposit date:2007-03-14
Release date:2008-01-29
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Solution Structure and Dynamics of the I214V Mutant of the Rabbit Prion Protein.
Plos One, 5, 2010