Author results

5EX7
  • Download 5ex7
  • View 5ex7
Molmil generated image of 5ex7
CRYSTAL STRUCTURE OF BRAT NHL DOMAIN IN COMPLEX WITH AN 8-NT HUNCHBACK MRNA
Descriptor:Brain tumor protein, RNA (5'-R(P*UP*UP*UP*GP*UP*UP*GP*U)-3')
Authors:Wang, Y., Yu, Z., Wang, M., Liu, C.P., Yang, N., Xu, R.M.
Deposit date:2015-11-23
Release date:2015-12-09
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal structure of Brat NHL domain in complex with an 8-nt hunchback mRNA
To Be Published
5XET
  • Download 5xet
  • View 5xet
Molmil generated image of 5xet
CRYSTAL STRUCTURE OF MYCOBACTERIUM TUBERCULOSIS METHIONYL-TRNA SYNTHETASE BOUND BY METHIONYL-ADENYLATE (MET-AMP)
Descriptor:Methionine--tRNA ligase, [[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxy-oxolan-2-yl]methoxy-hydroxy-phosphoryl] (2S)-2-azanyl-4-methylsulfanyl-butanoate, 1,2-ETHANEDIOL, ...
Authors:Wang, W., Qin, B., Wojdyla, J.A., Wang, M., Gao, X., Cui, S.
Deposit date:2017-04-06
Release date:2018-07-11
Last modified:2018-08-01
Method:X-RAY DIFFRACTION (2.38 Å)
Cite:Structural characterization of free-state and product-stateMycobacterium tuberculosismethionyl-tRNA synthetase reveals an induced-fit ligand-recognition mechanism.
IUCrJ, 5, 2018
5XGQ
  • Download 5xgq
  • View 5xgq
Molmil generated image of 5xgq
CRYSTAL STRUCTURE OF APO FORM (FREE-STATE) MYCOBACTERIUM TUBERCULOSIS METHIONYL-TRNA SYNTHETASE
Descriptor:Methionine-tRNA ligase
Authors:Wang, W., Wang, M., Wojdyla, J.A., Cui, S.
Deposit date:2017-04-15
Release date:2018-07-11
Last modified:2018-08-01
Method:X-RAY DIFFRACTION (1.899 Å)
Cite:Structural characterization of free-state and product-stateMycobacterium tuberculosismethionyl-tRNA synthetase reveals an induced-fit ligand-recognition mechanism
IUCrJ, 5, 2018
5Z3W
  • Download 5z3w
  • View 5z3w
Molmil generated image of 5z3w
MALATE DEHYDROGENASE BINDS SILVER AT C113
Descriptor:Malate dehydrogenase, SILVER ION
Authors:Wang, H., Wang, M., Sun, H.
Deposit date:2018-01-09
Release date:2019-01-16
Method:X-RAY DIFFRACTION (2.29 Å)
Cite:Structure of silver-bound malate dehydrogenase
To Be Published
5ZCJ
  • Download 5zcj
  • View 5zcj
Molmil generated image of 5zcj
CRYSTAL STRUCTURE OF COMPLEX
Descriptor:Tudor-interacting repair regulator protein, TP53-binding protein 1
Authors:Wang, J., Yuan, Z., Cui, Y., Xie, R., Wang, M., Ma, Y., Yu, X., Liu, X.
Deposit date:2018-02-17
Release date:2018-06-27
Method:X-RAY DIFFRACTION (2.004 Å)
Cite:Crystal structure of complex
To Be Published
6I59
  • Download 6i59
  • View 6i59
Molmil generated image of 6i59
LONG WAVELENGTH NATIVE-SAD PHASING OF SEN1 HELICASE
Descriptor:Helicase SEN1, ADENOSINE-5'-DIPHOSPHATE, 1,2-ETHANEDIOL, ...
Authors:Basu, S., Olieric, V., Matsugaki, N., Kawano, Y., Takashi, T., Huang, C.Y., Leonarski, F., Yamada, Y., Vera, L., Olieric, N., Basquin, J., Wojdyla, J.A., Diederichs, K., Yamamoto, M., Bunk, O., Wang, M.
Deposit date:2018-11-13
Release date:2019-03-13
Last modified:2019-06-12
Method:X-RAY DIFFRACTION (2.95 Å)
Cite:Long-wavelength native-SAD phasing: opportunities and challenges.
Iucrj, 6, 2019
4R8T
  • Download 4r8t
  • View 4r8t
Molmil generated image of 4r8t
STRUCTURE OF JEV PROTEASE
Descriptor:Serine protease subunit NS2B, NS3, CHLORIDE ION
Authors:Nair, D.T., Weinert, T., Wang, M., Olieric, V.
Deposit date:2014-09-03
Release date:2014-12-24
Last modified:2015-08-12
Method:X-RAY DIFFRACTION (2.133 Å)
Cite:Fast native-SAD phasing for routine macromolecular structure determination.
Nat.Methods, 12, 2015
4R8U
  • Download 4r8u
  • View 4r8u
Molmil generated image of 4r8u
S-SAD STRUCTURE OF DINB-DNA COMPLEX
Descriptor:DNA polymerase IV, DNA, MAGNESIUM ION, ...
Authors:Kottur, J., Nair, D.T., Weinert, T., Oligeric, V., Wang, M.
Deposit date:2014-09-03
Release date:2015-01-14
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Fast native-SAD phasing for routine macromolecular structure determination
Nat.Methods, 12, 2015
4WAB
  • Download 4wab
  • View 4wab
Molmil generated image of 4wab
CRYSTAL STRUCTURE OF MPGES1 SOLVED BY NATIVE-SAD PHASING
Descriptor:Prostaglandin E synthase,Leukotriene C4 synthase, GLUTATHIONE, 2-[[2,6-bis(chloranyl)-3-[(2,2-dimethylpropanoylamino)methyl]phenyl]amino]-1-methyl-6-(2-methyl-2-oxidanyl-propoxy)-N-[2,2,2-tris(fluoranyl)ethyl]benzimidazole-5-carboxamide
Authors:Weinert, T., Li, D., Howe, N., Caffrey, M., Wang, M.
Deposit date:2014-08-29
Release date:2014-12-10
Last modified:2015-02-11
Method:X-RAY DIFFRACTION (2.704 Å)
Cite:Fast native-SAD phasing for routine macromolecular structure determination.
Nat.Methods, 12, 2015
4WAU
  • Download 4wau
  • View 4wau
Molmil generated image of 4wau
CRYSTAL STRUCTURE OF CENP-M SOLVED BY NATIVE-SAD PHASING
Descriptor:Centromere protein M
Authors:Weinert, T., Basilico, F., Cecatiello, V., Pasqualato, S., Wang, M.
Deposit date:2014-09-01
Release date:2014-12-10
Last modified:2015-02-11
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Fast native-SAD phasing for routine macromolecular structure determination.
Nat.Methods, 12, 2015
4WBQ
  • Download 4wbq
  • View 4wbq
Molmil generated image of 4wbq
CRYSTAL STRUCTURE OF THE EXONUCLEASE DOMAIN OF QIP (QDE-2 INTERACTING PROTEIN) SOLVED BY NATIVE-SAD PHASING.
Descriptor:QDE-2-interacting protein, CALCIUM ION
Authors:Boland, A., Weinert, T., Weichenrieder, O., Wang, M.
Deposit date:2014-09-03
Release date:2014-12-10
Last modified:2015-02-11
Method:X-RAY DIFFRACTION (2.693 Å)
Cite:Fast native-SAD phasing for routine macromolecular structure determination.
Nat.Methods, 12, 2015
3ZJ6
  • Download 3zj6
  • View 3zj6
Molmil generated image of 3zj6
CRYSTAL OF RAUCAFFRICINE GLUCOSIDASE IN COMPLEX WITH INHIBITOR
Descriptor:RAUCAFFRICINE-O-BETA-D-GLUCOSIDASE, SULFATE ION, (1R,2S,3S,4R,5R)-4-(cyclohexylmethylamino)-5-(hydroxymethyl)cyclopentane-1,2,3-triol
Authors:Xia, L., Lin, H., Panjikar, S., Ruppert, M., Castiglia, A., Rajendran, C., Wang, M., Schuebel, H., Warzecha, H., Jaeger, V., Stoeckigt, J.
Deposit date:2013-01-17
Release date:2014-01-29
Last modified:2015-07-22
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Ligand Structures of Synthetic Deoxa-Pyranosylamines with Raucaffricine and Strictosidine Glucosidases Provide Structural Insights Into Their Binding and Inhibitory Behaviours.
J.Enzyme.Inhib.Med.Chem., 30, 2015
4ATD
  • Download 4atd
  • View 4atd
Molmil generated image of 4atd
CRYSTAL STRUCTURE OF NATIVE RAUCAFFRICINE GLUCOSIDASE
Descriptor:RAUCAFFRICINE-O-BETA-D-GLUCOSIDASE, SULFATE ION
Authors:Xia, L., Rajendran, C., Ruppert, M., Panjikar, S., Wang, M., Stoeckigt, J.
Deposit date:2012-05-05
Release date:2013-01-16
Last modified:2013-06-19
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:High Speed X-Ray Analysis of Plant Enzymes at Room Temperature
Phytochemistry, 91, 2013
4ATL
  • Download 4atl
  • View 4atl
Molmil generated image of 4atl
CRYSTAL STRUCTURE OF RAUCAFFRICINE GLUCOSIDASE IN COMPLEX WITH GLUCOSE
Descriptor:RAUCAFFRICINE-O-BETA-D-GLUCOSIDASE, BETA-D-GLUCOSE
Authors:Xia, L., Rajendran, C., Ruppert, M., Panjikar, S., Wang, M., Stoeckigt, J.
Deposit date:2012-05-08
Release date:2013-01-30
Last modified:2013-08-07
Method:X-RAY DIFFRACTION (2.52 Å)
Cite:High Speed X-Ray Analysis of Plant Enzymes at Room Temperature
Phytochemistry, 91, 2013
6I5C
  • Download 6i5c
  • View 6i5c
Molmil generated image of 6i5c
LONG WAVELENGTH NATIVE-SAD PHASING OF TUBULIN-STATHMIN-TTL COMPLEX
Descriptor:Tubulin alpha-1B chain, Tubulin beta-2B chain, Stathmin-4, ...
Authors:Basu, S., Olieric, V., Matsugaki, N., Kawano, Y., Takashi, T., Huang, C.Y., Leonarski, F., Yamada, Y., Vera, L., Olieric, N., Basquin, J., Wojdyla, J.A., Diederichs, K., Yamamoto, M., Bunk, O., Wang, M.
Deposit date:2018-11-13
Release date:2019-03-13
Last modified:2019-05-29
Method:X-RAY DIFFRACTION (2.95 Å)
Cite:Long-wavelength native-SAD phasing: opportunities and challenges.
Iucrj, 6, 2019
1Y0H
  • Download 1y0h
  • View 1y0h
Molmil generated image of 1y0h
STRUCTURE OF RV0793 FROM MYCOBACTERIUM TUBERCULOSIS
Descriptor:hypothetical protein Rv0793, ACETATE ION
Authors:Lemieux, M.J., Ference, C., Cherney, M.M., Wang, M., Garen, C., James, M.N., TB Structural Genomics Consortium (TBSGC)
Deposit date:2004-11-15
Release date:2004-12-28
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:The crystal structure of Rv0793, a hypothetical monooxygenase from M. tuberculosis
J.STRUCT.FUNCT.GENOM., 6, 2005
2AKJ
  • Download 2akj
  • View 2akj
Molmil generated image of 2akj
STRUCTURE OF SPINACH NITRITE REDUCTASE
Descriptor:Ferredoxin--nitrite reductase, chloroplast, IRON/SULFUR CLUSTER, ...
Authors:Swamy, U., Wang, M., Tripathy, J.N., Kim, S.-K., Hirasawa, M., Knaff, D.B., Allen, J.P.
Deposit date:2005-08-03
Release date:2006-01-24
Last modified:2018-04-04
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structure of Spinach Nitrite Reductase: Implications for Multi-electron Reactions by the Iron-Sulfur:Siroheme Cofactor
Biochemistry, 44, 2005
2P05
  • Download 2p05
  • View 2p05
Molmil generated image of 2p05
STRUCTURAL INSIGHTS INTO THE EVOLUTION OF A NON-BIOLOGICAL PROTEIN
Descriptor:a non-biological ATP binding protein 1819, ZINC ION, CHLORIDE ION, ...
Authors:Smith, M., Rosenow, M., Wang, M., Allen, J.P., Szostak, J.W., Chaput, J.C.
Deposit date:2007-02-28
Release date:2007-06-05
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural insights into the evolution of a non-biological protein: importance of surface residues in protein fold optimization.
PLoS ONE, 2, 2007
2P09
  • Download 2p09
  • View 2p09
Molmil generated image of 2p09
STRUCTURAL INSIGHTS INTO THE EVOLUTION OF A NON-BIOLOGICAL PROTEIN
Descriptor:a non-biological ATP binding protein with two mutations N32D and D65V, ZINC ION, CHLORIDE ION, ...
Authors:Smith, M., Rosenow, M., Wang, M., Allen, J.P., Szostak, J.W., Chaput, J.C.
Deposit date:2007-02-28
Release date:2007-06-05
Last modified:2018-04-04
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Structural insights into the evolution of a non-biological protein: importance of surface residues in protein fold optimization.
PLoS ONE, 2, 2007
2WFL
  • Download 2wfl
  • View 2wfl
Molmil generated image of 2wfl
CRYSTAL STRUCTURE OF POLYNEURIDINE ALDEHYDE ESTERASE
Descriptor:POLYNEURIDINE-ALDEHYDE ESTERASE, SULFATE ION
Authors:Yang, L., Hill, M., Panjikar, S., Wang, M., Stoeckigt, J.
Deposit date:2009-04-08
Release date:2009-08-18
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural Basis and Enzymatic Mechanism of the Biosynthesis of C9- from C10-Monoterpenoid Indole Alkaloids.
Angew.Chem.Int.Ed.Engl., 48, 2009
2WFM
  • Download 2wfm
  • View 2wfm
Molmil generated image of 2wfm
CRYSTAL STRUCTURE OF POLYNEURIDINE ALDEHYDE ESTERASE MUTANT (H244A)
Descriptor:POLYNEURIDINE ALDEHYDE ESTERASE
Authors:Yang, L., Hill, M., Panjikar, S., Wang, M., Stoeckigt, J.
Deposit date:2009-04-08
Release date:2010-04-21
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural Basis and Enzymatic Mechanism of the Biosynthesis of C9- from C10-Monoterpenoid Indole Alkaloids.
Angew.Chem.Int.Ed.Engl., 48, 2009
3GZJ
  • Download 3gzj
  • View 3gzj
Molmil generated image of 3gzj
CRYSTAL STRUCTURE OF POLYNEURIDINE ALDEHYDE ESTERASE COMPLEXED WITH 16-EPI-VELLOSIMINE
Descriptor:Polyneuridine-aldehyde esterase, 16-epi-Vellosimine
Authors:Yang, L., Hill, M., Wang, M., Panjikar, S., Stoeckigt, J.
Deposit date:2009-04-07
Release date:2009-08-18
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (2.19 Å)
Cite:Structural basis and enzymatic mechanism of the biosynthesis of C9- from C10-monoterpenoid indole alkaloids
Angew.Chem.Int.Ed.Engl., 48, 2009
3U57
  • Download 3u57
  • View 3u57
Molmil generated image of 3u57
STRUCTURES OF ALKALOID BIOSYNTHETIC GLUCOSIDASES DECODE SUBSTRATE SPECIFICITY
Descriptor:Raucaffricine-O-beta-D-glucosidase, (2beta,7beta,16S,17R,19E,21beta)-21-(beta-D-glucopyranosyloxy)-2,7-dihydro-7,17-cyclosarpagan-17-yl acetate, CHLORIDE ION
Authors:Xia, L., Ruppert, M., Wang, M., Panjikar, S., Lin, H., Rajendran, C., Barleben, L., Stoeckigt, J.
Deposit date:2011-10-11
Release date:2011-11-30
Last modified:2013-07-10
Method:X-RAY DIFFRACTION (2.43 Å)
Cite:Structures of alkaloid biosynthetic glucosidases decode substrate specificity.
Acs Chem.Biol., 7, 2012
3U5U
  • Download 3u5u
  • View 3u5u
Molmil generated image of 3u5u
STRUCTURES OF ALKALOID BIOSYNTHETIC GLUCOSIDASES DECODE SUBSTRATE SPECIFICITY
Descriptor:Raucaffricine-O-beta-D-glucosidase, CHLORIDE ION
Authors:Xia, L., Ruppert, M., Wang, M., Panjikar, S., Lin, H., Rajendran, C., Barleben, L., Stoeckigt, J.
Deposit date:2011-10-11
Release date:2011-11-30
Last modified:2013-07-10
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structures of alkaloid biosynthetic glucosidases decode substrate specificity.
Acs Chem.Biol., 7, 2012
3U5Y
  • Download 3u5y
  • View 3u5y
Molmil generated image of 3u5y
STRUCTURES OF ALKALOID BIOSYNTHETIC GLUCOSIDASES DECODE SUBSTRATE SPECIFICITY
Descriptor:Raucaffricine-O-beta-D-glucosidase, METHYL (2S,3R,4S)-2-(BETA-D-GLUCOPYRANOSYLOXY)-4-(2-OXOETHYL)-3-VINYL-3,4-DIHYDRO-2H-PYRAN-5-CARBOXYLATE, CHLORIDE ION
Authors:Xia, L., Ruppert, M., Wang, M., Panjikar, S., Lin, H., Rajendran, C., Barleben, L., Stoeckigt, J.
Deposit date:2011-10-11
Release date:2011-11-30
Last modified:2013-07-10
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structures of alkaloid biosynthetic glucosidases decode substrate specificity.
Acs Chem.Biol., 7, 2012