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4E5Y
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BU of 4e5y by Molmil
Structure of human FX protein, the key enzyme in the biosynthesis of GDP-L-fucose
Descriptor: GDP-L-fucose synthase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
Authors:Zhou, H, He, J.H.
Deposit date:2012-03-15
Release date:2013-04-17
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.37 Å)
Cite:Structure of human FX protein, the key enzyme in the biosynthesis of GDP-L-fucose
To be Published
3H3B
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BU of 3h3b by Molmil
Crystal structure of the single-chain Fv (scFv) fragment of an anti-ErbB2 antibody chA21 in complex with residues 1-192 of ErbB2 extracellular domain
Descriptor: Receptor tyrosine-protein kinase erbB-2, anti-ErbB2 antibody chA21
Authors:Zhou, H, Liu, Y, Niu, L, Zhu, J, Teng, M.
Deposit date:2009-04-16
Release date:2010-04-28
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Structural Insights into the Down-regulation of Overexpressed p185her2/neu Protein of Transformed Cells by the Antibody chA21.
J.Biol.Chem., 286, 2011
7SHK
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BU of 7shk by Molmil
Structure of Xenopus laevis CRL2Lrr1 (State 1)
Descriptor: CULLIN_2 domain-containing protein, Elongin-C, Lrr1, ...
Authors:Zhou, H, Brown, A.
Deposit date:2021-10-09
Release date:2021-12-08
Last modified:2021-12-29
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Structure of CRL2Lrr1, the E3 ubiquitin ligase that promotes DNA replication termination in vertebrates.
Nucleic Acids Res., 49, 2021
7SHL
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BU of 7shl by Molmil
Structure of Xenopus laevis CRL2Lrr1 (State 2)
Descriptor: CULLIN_2 domain-containing protein, Elongin-C, Lrr1, ...
Authors:Zhou, H, Brown, A.
Deposit date:2021-10-09
Release date:2021-12-08
Last modified:2021-12-29
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Structure of CRL2Lrr1, the E3 ubiquitin ligase that promotes DNA replication termination in vertebrates.
Nucleic Acids Res., 49, 2021
2HGF
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BU of 2hgf by Molmil
HAIRPIN LOOP CONTAINING DOMAIN OF HEPATOCYTE GROWTH FACTOR, NMR, MINIMIZED AVERAGE STRUCTURE
Descriptor: HEPATOCYTE GROWTH FACTOR
Authors:Zhou, H, Mazzulla, M.J, Kaufman, J.D, Stahl, S.J, Wingfield, P.T, Rubin, J.S, Bottaro, D.P, Byrd, R.A.
Deposit date:1997-12-18
Release date:1998-06-24
Last modified:2022-03-09
Method:SOLUTION NMR
Cite:The solution structure of the N-terminal domain of hepatocyte growth factor reveals a potential heparin-binding site.
Structure, 6, 1998
4XEM
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BU of 4xem by Molmil
Crystal Structure of wild type human AlaRS catalytic domain
Descriptor: '5'-O-(N-(L-ALANYL)-SULFAMOYL)ADENOSINE, 1,2-ETHANEDIOL, Alanine--tRNA ligase, ...
Authors:Zhou, H, He, W, Yang, X.L.
Deposit date:2014-12-24
Release date:2016-02-17
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.278 Å)
Cite:Crystal structure of wild type human AlaRS catalytic domain
To Be Published
1T2M
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BU of 1t2m by Molmil
Solution Structure Of The Pdz Domain Of AF-6
Descriptor: AF-6 protein
Authors:Zhou, H, Wu, J.H, Xu, Y.Q, Huang, A.D, Shi, Y.Y.
Deposit date:2004-04-22
Release date:2005-02-08
Last modified:2022-03-02
Method:SOLUTION NMR
Cite:Solution Structure of AF-6 PDZ Domain and Its Interaction with the C-terminal Peptides from Neurexin and Bcr
J.Biol.Chem., 280, 2005
6J11
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BU of 6j11 by Molmil
MERS-CoV spike N-terminal domain and 7D10 scFv complex
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, N-terminal domain of Spike glycoprotein, ...
Authors:Zhou, H, Zhang, S, Zhang, S, Tang, W, Wang, X.
Deposit date:2018-12-27
Release date:2019-07-24
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structural definition of a neutralization epitope on the N-terminal domain of MERS-CoV spike glycoprotein.
Nat Commun, 10, 2019
4HVC
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BU of 4hvc by Molmil
Crystal structure of human prolyl-tRNA synthetase in complex with halofuginone and ATP analogue
Descriptor: 7-bromo-6-chloro-3-{3-[(2R,3S)-3-hydroxypiperidin-2-yl]-2-oxopropyl}quinazolin-4(3H)-one, Bifunctional glutamate/proline--tRNA ligase, MAGNESIUM ION, ...
Authors:Zhou, H, Sun, L, Yang, X.L, Schimmel, P.
Deposit date:2012-11-06
Release date:2013-01-02
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2 Å)
Cite:ATP-directed capture of bioactive herbal-based medicine on human tRNA synthetase.
Nature, 494, 2012
3Q19
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BU of 3q19 by Molmil
Human Glutathione Transferase O2
Descriptor: CHLORIDE ION, GLUTATHIONE, Glutathione S-transferase omega-2
Authors:Zhou, H, Board, P.G, Oakley, A.J.
Deposit date:2010-12-16
Release date:2012-01-25
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural insights into the dehydroascorbate reductase activity of human omega-class glutathione transferases.
J.Mol.Biol., 420, 2012
3Q18
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BU of 3q18 by Molmil
Human Glutathione Transferase O2
Descriptor: CHLORIDE ION, DI(HYDROXYETHYL)ETHER, GLYCEROL, ...
Authors:Zhou, H, Board, P.G, Oakley, A.J.
Deposit date:2010-12-16
Release date:2012-01-25
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structural insights into the dehydroascorbate reductase activity of human omega-class glutathione transferases.
J.Mol.Biol., 420, 2012
3PSM
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BU of 3psm by Molmil
.98A crystal structure of a dimeric plant defensin SPE10
Descriptor: Defensin
Authors:Zhou, H, Song, X, Gong, W.
Deposit date:2010-12-01
Release date:2010-12-29
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (0.98 Å)
Cite:0.98A crystal structure of a dimeric plant defensin SPE10
To be Published
3QAG
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BU of 3qag by Molmil
Human Glutathione Transferase O2 with glutathione -new crystal form
Descriptor: 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, GLUTATHIONE, ...
Authors:Zhou, H, Board, P.G, Oakley, A.J.
Deposit date:2011-01-11
Release date:2012-01-11
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural insights into the dehydroascorbate reductase activity of human omega-class glutathione transferases.
J.Mol.Biol., 420, 2012
6KJ3
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BU of 6kj3 by Molmil
120kV MicroED structure of FUS (37-42) SYSGYS solved from merged datasets at 0.60 A
Descriptor: RNA-binding protein FUS
Authors:Zhou, H, Luo, F, Luo, Z, Li, D, Liu, C, Li, X.
Deposit date:2019-07-20
Release date:2019-10-02
Last modified:2024-03-27
Method:ELECTRON CRYSTALLOGRAPHY (0.6 Å)
Cite:Programming Conventional Electron Microscopes for Solving Ultrahigh-Resolution Structures of Small and Macro-Molecules.
Anal.Chem., 91, 2019
6KJ4
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BU of 6kj4 by Molmil
120kV MicroED structure of FUS (37-42) SYSGYS solved from single crystal at 0.65 A
Descriptor: RNA-binding protein FUS
Authors:Zhou, H, Luo, F, Luo, Z, Li, D, Liu, C, Li, X.
Deposit date:2019-07-20
Release date:2019-10-02
Last modified:2024-03-27
Method:ELECTRON CRYSTALLOGRAPHY (0.65 Å)
Cite:Programming Conventional Electron Microscopes for Solving Ultrahigh-Resolution Structures of Small and Macro-Molecules.
Anal.Chem., 91, 2019
6KJ2
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BU of 6kj2 by Molmil
200kV MicroED structure of FUS (37-42) SYSGYS solved from single crystal at 0.67 A
Descriptor: RNA-binding protein FUS
Authors:Zhou, H, Luo, F, Luo, Z, Li, D, Liu, C, Li, X.
Deposit date:2019-07-20
Release date:2019-10-02
Last modified:2024-03-27
Method:ELECTRON CRYSTALLOGRAPHY (0.67 Å)
Cite:Programming Conventional Electron Microscopes for Solving Ultrahigh-Resolution Structures of Small and Macro-Molecules.
Anal.Chem., 91, 2019
6KJ1
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BU of 6kj1 by Molmil
200kV MicroED structure of FUS (37-42) SYSGYS solved from merged datasets at 0.65 A
Descriptor: RNA-binding protein FUS
Authors:Zhou, H, Luo, F, Luo, Z, Li, D, Liu, C, Li, X.
Deposit date:2019-07-20
Release date:2019-10-02
Last modified:2024-03-27
Method:ELECTRON CRYSTALLOGRAPHY (0.65 Å)
Cite:Programming Conventional Electron Microscopes for Solving Ultrahigh-Resolution Structures of Small and Macro-Molecules.
Anal.Chem., 91, 2019
6LAW
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BU of 6law by Molmil
MicroED structure of proteinase K at 1.50A determained using crystal lamellas prepared by focused ion beam milling
Descriptor: Proteinase K, SULFATE ION
Authors:Zhou, H, Luo, Z, Li, X.
Deposit date:2019-11-13
Release date:2019-12-04
Method:ELECTRON CRYSTALLOGRAPHY (1.5 Å)
Cite:Using focus ion beam to prepare crystal lamella for electron diffraction.
J. Struct. Biol., 205, 2019
6LAV
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BU of 6lav by Molmil
MicroED structure of lysozyme at 1.73A determained using crystal lamellas prepared by focused ion beam milling
Descriptor: ACETATE ION, Lysozyme C
Authors:Zhou, H, Luo, Z, Li, X.
Deposit date:2019-11-13
Release date:2019-11-27
Method:ELECTRON CRYSTALLOGRAPHY (1.73 Å)
Cite:Using focus ion beam to prepare crystal lamella for electron diffraction.
J. Struct. Biol., 205, 2019
6A68
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BU of 6a68 by Molmil
the crystal structure of rat calcium-dependent activator protein for secretion (CAPS) DAMH domain
Descriptor: Calcium-dependent secretion activator 1, POTASSIUM ION
Authors:Zhou, H, Wei, Z.Q, Yao, D.Q, Zhang, R.G, Ma, C.
Deposit date:2018-06-26
Release date:2019-03-13
Last modified:2019-11-20
Method:X-RAY DIFFRACTION (2.901 Å)
Cite:Structural and Functional Analysis of the CAPS SNARE-Binding Domain Required for SNARE Complex Formation and Exocytosis.
Cell Rep, 26, 2019
5V58
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BU of 5v58 by Molmil
Crystal structure of human prolyl-tRNA synthetase in complex with Aze-SA
Descriptor: 5'-O-{[(2S)-azetidine-2-carbonyl]sulfamoyl}adenosine, Bifunctional glutamate/proline--tRNA ligase, ZINC ION
Authors:Zhou, H, Song, Y, Schimmel, P.
Deposit date:2017-03-13
Release date:2018-01-10
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.59 Å)
Cite:Double mimicry evades tRNA synthetase editing by toxic vegetable-sourced non-proteinogenic amino acid.
Nat Commun, 8, 2017
5V59
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BU of 5v59 by Molmil
Crystal structure of catalytic fragment of human AlaRS in complex with Aze-SA
Descriptor: 5'-O-{[(2S)-azetidine-2-carbonyl]sulfamoyl}adenosine, Alanine--tRNA ligase, cytoplasmic
Authors:Zhou, H, Song, Y, Schimmel, P.
Deposit date:2017-03-13
Release date:2018-01-10
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.03 Å)
Cite:Double mimicry evades tRNA synthetase editing by toxic vegetable-sourced non-proteinogenic amino acid.
Nat Commun, 8, 2017
5HXW
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BU of 5hxw by Molmil
L-amino acid deaminase from Proteus vulgaris
Descriptor: CETYL-TRIMETHYL-AMMONIUM, FLAVIN-ADENINE DINUCLEOTIDE, L-amino acid deaminase
Authors:Zhou, H, Ju, Y, Niu, L, Teng, M.
Deposit date:2016-01-31
Release date:2016-08-03
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.63 Å)
Cite:Crystal structure of a membrane-bound l-amino acid deaminase from Proteus vulgaris
J.Struct.Biol., 195, 2016
5I39
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BU of 5i39 by Molmil
High resolution structure of L-amino acid deaminase from Proteus vulgaris with the deletion of the specific insertion sequence
Descriptor: 1,2-ETHANEDIOL, FLAVIN-ADENINE DINUCLEOTIDE, L-amino acid deaminase
Authors:Zhou, H, Ju, Y, Niu, L, Teng, M.
Deposit date:2016-02-10
Release date:2016-08-03
Last modified:2016-08-24
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:Crystal structure of a membrane-bound l-amino acid deaminase from Proteus vulgaris
J.Struct.Biol., 195, 2016
8F5P
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BU of 8f5p by Molmil
Structure of Leishmania tarentolae IFT-A (state 2)
Descriptor: Intraflagellar transport protein 122 homolog, Intraflagellar transport protein 122B, putative, ...
Authors:Zhou, H, Brown, A.
Deposit date:2022-11-14
Release date:2022-12-21
Last modified:2023-01-11
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Mechanism of IFT-A polymerization into trains for ciliary transport.
Cell, 185, 2022

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