Author results

5D9Y
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CRYSTAL STRUCTURE OF TET2-5FC COMPLEX
分子名称:Methylcytosine dioxygenase TET2,Methylcytosine dioxygenase TET2, DNA (5'-D(*AP*CP*TP*GP*TP*(5FC)P*GP*AP*AP*GP*CP*T)-3'), DNA (5'-D(*AP*GP*CP*TP*TP*CP*GP*AP*CP*AP*GP*T)-3'), ...
著者Hu, L., Cheng, J., Rao, Q., Li, Z., Li, J., Xu, Y.
登録日2015-08-19
公開日2015-11-04
最終更新日2015-11-18
実験手法X-RAY DIFFRACTION (1.971 Å)
主引用文献Structural insight into substrate preference for TET-mediated oxidation.
Nature, 527, 2015
5DEU
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CRYSTAL STRUCTURE OF TET2-5HMC COMPLEX
分子名称:Methylcytosine dioxygenase TET2, chimeric construct, DNA (5'-D(*AP*CP*CP*AP*CP*(5HC)P*GP*GP*TP*GP*GP*T)-3'), ...
著者Hu, L., Cheng, J., Rao, Q., Li, Z., Li, J., Xu, Y.
登録日2015-08-26
公開日2015-11-04
最終更新日2015-11-18
実験手法X-RAY DIFFRACTION (1.801 Å)
主引用文献Structural insight into substrate preference for TET-mediated oxidation.
Nature, 527, 2015
2AXH
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CRYSTAL STRUCTURES OF T CELL RECEPTOR BETA CHAINS RELATED TO RHEUMATOID ARTHRITIS
分子名称:T cell receptor beta chain
著者Li, H., Van Vranken, S., Zhao, Y., Li, Z., Guo, Y., Eisele, L., Li, Y.
登録日2005-09-05
公開日2005-09-20
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Crystal structures of T cell receptor (beta) chains related to rheumatoid arthritis.
Protein Sci., 14, 2005
2AXJ
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CRYSTAL STRUCTURES OF T CELL RECEPTOR BETA CHAINS RELATED TO RHEUMATOID ARTHRITIS
分子名称:SF4 T cell receptor beta chain
著者Li, H., Van Vranken, S., Zhao, Y., Li, Z., Guo, Y., Eisele, L., Li, Y.
登録日2005-09-05
公開日2005-09-20
最終更新日2017-10-11
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献Crystal structures of T cell receptor (beta) chains related to rheumatoid arthritis.
Protein Sci., 14, 2005
1R5I
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CRYSTAL STRUCTURE OF THE MAM-MHC COMPLEX
分子名称:HLA class II histocompatibility antigen, DR alpha chain, DRB1-1 beta chain, ...
著者Zhao, Y., Li, Z., Drozd, S.J., Guo, Y., Mourad, W., Li, H.
登録日2003-10-10
公開日2004-03-16
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Crystal structure of Mycoplasma arthritidis mitogen complexed with HLA-DR1 reveals a novel superantigen fold and a dimerized superantigen-MHC complex.
Structure, 12, 2004
2OJE
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MYCOPLASMA ARTHRITIDIS-DERIVED MITOGEN COMPLEXED WITH CLASS II MHC MOLECULE HLA-DR1/HA COMPLEX IN THE PRESENCE OF EDTA
分子名称:HLA class II histocompatibility antigen, DR alpha chain precursor, DRB1-1 beta chain precursor, ...
著者Li, H., Zhao, Y., Guo, Y., Li, Z., Eisele, L., Mourad, W.
登録日2007-01-12
公開日2007-01-23
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Zinc induces dimerization of the class II major histocompatibility complex molecule that leads to cooperative binding to a superantigen.
J.Biol.Chem., 282, 2007
3J8G
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ELECTRON CRYO-MICROSCOPY STRUCTURE OF ENGA BOUND WITH THE 50S RIBOSOMAL SUBUNIT
分子名称:5S rRNA, 23S rRNA, 50S ribosomal protein L28, ...
著者Zhang, X., Yan, K., Zhang, Y., Li, N., Ma, C., Li, Z., Zhang, Y., Feng, B., Liu, J., Sun, Y., Xu, Y., Lei, J., Gao, N.
登録日2014-10-24
公開日2014-11-26
実験手法ELECTRON MICROSCOPY (5 Å)
主引用文献Structural insights into the function of a unique tandem GTPase EngA in bacterial ribosome assembly
Nucleic Acids Res., 2014
3KUP
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CRYSTAL STRUCTURE OF THE CBX3 CHROMO SHADOW DOMAIN
分子名称:Chromobox protein homolog 3, UNKNOWN ATOM OR ION
著者Tempel, W., Li, Z., Li, Y., Kozieradzki, I., Bountra, C., Weigelt, J., Arrowsmith, C.H., Edwards, A.M., Bochkarev, A., Min, J., Ouyang, H., Structural Genomics Consortium (SGC)
登録日2009-11-27
公開日2009-12-08
最終更新日2017-11-01
実験手法X-RAY DIFFRACTION (1.77 Å)
主引用文献Crystal Structure of the CBX3 Chromo Shadow Domain
to be published
3R93
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CRYSTAL STRUCTURE OF THE CHROMO DOMAIN OF M-PHASE PHOSPHOPROTEIN 8 BOUND TO H3K9ME3 PEPTIDE
分子名称:M-phase phosphoprotein 8, H3K9Me3 peptide, UNKNOWN ATOM OR ION
著者Li, J., Li, Z., Ruan, J., Xu, C., Tong, Y., Pan, P.W., Tempel, W., Crombet, L., Min, J., Zang, J., Structural Genomics Consortium (SGC)
登録日2011-03-24
公開日2011-04-06
最終更新日2017-11-08
実験手法X-RAY DIFFRACTION (2.057 Å)
主引用文献Structural basis for specific binding of human MPP8 chromodomain to histone H3 methylated at lysine 9.
Plos One, 6, 2011
3ZIU
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CRYSTAL STRUCTURE OF MYCOPLASMA MOBILE LEUCYL-TRNA SYNTHETASE WITH LEU-AMS IN THE ACTIVE SITE
分子名称:LEUCYL-TRNA SYNTHETASE, 5'-O-(L-leucylsulfamoyl)adenosine, GLYCEROL
著者Li, L., Palencia, A., Lukk, T., Li, Z., Luthey-Schulten, Z.A., Cusack, S., Martinis, S.A., Boniecki, M.T.
登録日2013-01-10
公開日2013-02-27
最終更新日2013-03-20
実験手法X-RAY DIFFRACTION (2.07 Å)
主引用文献Leucyl-tRNA Synthetase Editing Domain Functions as a Molecular Rheostat to Control Codon Ambiguity in Mycoplasma Pathogens.
Proc.Natl.Acad.Sci.USA, 110, 2013
4LAK
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CRYSTAL STRUCTURE OF CORDYCEPS MILITARIS IDCASE D323N MUTANT IN APO FORM
分子名称:Uracil-5-carboxylate decarboxylase, ZINC ION
著者Xu, S., Li, W., Zhu, J., Wang, R., Li, Z., Xu, G.L., Ding, J.
登録日2013-06-20
公開日2013-10-02
最終更新日2017-11-15
実験手法X-RAY DIFFRACTION (2.41 Å)
主引用文献Crystal structures of isoorotate decarboxylases reveal a novel catalytic mechanism of 5-carboxyl-uracil decarboxylation and shed light on the search for DNA decarboxylase.
Cell Res., 23, 2013
4R05
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CRYSTAL STRUCTURE OF THE REFOLDED DENV3 METHYLTRANSFERASE
分子名称:Nonstructural protein NS5
著者Brecher, M.B., Li, Z., Zhang, J., Chen, H., Lin, Q., Liu, B., Li, H.M.
登録日2014-07-29
公開日2014-11-12
最終更新日2015-01-21
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Refolding of a fully functional flavivirus methyltransferase revealed that S-adenosyl methionine but not S-adenosyl homocysteine is copurified with flavivirus methyltransferase.
Protein Sci., 24, 2015
4Y07
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CRYSTAL STRUCTURE OF THE HECT DOMAIN OF HUMAN WWP2
分子名称:NEDD4-like E3 ubiquitin-protein ligase WWP2
著者Gong, W., Li, J., Li, Z., Xu, Y.
登録日2015-02-05
公開日2015-11-04
実験手法X-RAY DIFFRACTION (2.507 Å)
主引用文献Structure of the HECT domain of human WWP2
Acta Crystallogr.,Sect.F, 71, 2015
5CUQ
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IDENTIFICATION AND CHARACTERIZATION OF NOVEL BROAD SPECTRUM INHIBITORS OF THE FLAVIVIRUS METHYLTRANSFERASE
分子名称:Nonstructural protein NS5, N,N'-BIS(4-AMINO-2-METHYLQUINOLIN-6-YL)UREA
著者Brecher, B., Chen, H., Li, Z., Banavali, N.K., Jones, S.A., Zhang, J., Kramer, L.D., Li, H.M.
登録日2015-07-24
公開日2016-02-03
最終更新日2017-09-27
実験手法X-RAY DIFFRACTION (1.696 Å)
主引用文献Identification and Characterization of Novel Broad-Spectrum Inhibitors of the Flavivirus Methyltransferase.
Acs Infect Dis., 1, 2015
5DV9
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CRYSTAL STRUCTURE OF THE LUCIFERASE
分子名称:Luciferin 4-monooxygenase
著者Su, J., Li, Z., Yuan, Z., Gu, L.
登録日2015-09-21
公開日2016-09-28
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Crystal structure of the Luciferase
To Be Published
5DWV
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CRYSTAL STRUCTURE OF THE LUCIFERASE COMPLEXED WITH SUBSTRATE ANALOGUE
分子名称:Luciferin 4-monooxygenase, 2-[6-(cyclobuta-1,3-dien-1-ylamino)-1,3-benzothiazol-2-yl]-1,3-thiazol-4-ol
著者Su, J., Li, Z., Yuan, Z., Gu, L.
登録日2015-09-23
公開日2016-09-28
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal structure of the Luciferase complexed with substrate analogue
To Be Published
5H4P
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STRUCTURAL SNAPSHOT OF CYTOPLASMIC PRE-60S RIBOSOMAL PARTICLES BOUND WITH NMD3, LSG1, TIF6 AND REH1
分子名称:25S ribosomal RNA, 5S ribosomal RNA, 5.8S ribosomal RNA, ...
著者Ma, C., Wu, S., Li, N., Chen, Y., Yan, K., Li, Z., Zheng, L., Lei, J., Woolford, J.L., Gao, N.
登録日2016-11-01
公開日2017-01-25
最終更新日2017-06-14
実験手法ELECTRON MICROSCOPY (3.07 Å)
主引用文献Structural snapshot of cytoplasmic pre-60S ribosomal particles bound by Nmd3, Lsg1, Tif6 and Reh1
Nat. Struct. Mol. Biol., 24, 2017
5XWP
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CRYSTAL STRUCTURE OF LBUCAS13A-CRRNA-TARGET RNA TERNARY COMPLEX
分子名称:Uncharacterized protein, RNA (59-MER), RNA (30-MER)
著者Liu, L., Li, X., Li, Z., Wang, Y.
登録日2017-06-30
公開日2017-09-13
最終更新日2017-10-18
実験手法X-RAY DIFFRACTION (3.086 Å)
主引用文献The Molecular Architecture for RNA-Guided RNA Cleavage by Cas13a.
Cell, 170, 2017
5XWY
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ELECTRON CRYO-MICROSCOPY STRUCTURE OF LBUCAS13A-CRRNA BINARY COMPLEX
分子名称:A type VI-A CRISPR-Cas RNA-guided RNA ribonuclease, Cas13a, RNA (59-MER)
著者Zhang, X., Wang, Y., Ma, J., Liu, L., Li, X., Li, Z., You, L., Wang, J., Wang, M.
登録日2017-06-30
公開日2017-09-13
最終更新日2018-10-24
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献The Molecular Architecture for RNA-Guided RNA Cleavage by Cas13a.
Cell, 170, 2017
5Z96
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STRUCTURE OF THE MOUSE TRPC4 ION CHANNEL
分子名称:Short transient receptor potential channel 4, CHOLESTEROL HEMISUCCINATE, 2-(HEXADECANOYLOXY)-1-[(PHOSPHONOOXY)METHYL]ETHYL HEXADECANOATE, ...
著者Duan, J., Li, Z., Li, J., Zhang, J.
登録日2018-02-02
公開日2018-04-18
最終更新日2018-08-29
実験手法ELECTRON MICROSCOPY (3.28 Å)
主引用文献Structure of the mouse TRPC4 ion channel.
Nat Commun, 9, 2018
5ZX5
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3.3 ANGSTROM STRUCTURE OF MOUSE TRPM7 WITH EDTA
分子名称:Transient receptor potential cation channel subfamily M member 7, CHOLESTEROL HEMISUCCINATE
著者Zhang, J., Li, Z., Duan, J., Li, J., Hulse, R.E., Santa-Cruz, A., Abiria, S.A., Krapivinsky, G., Clapham, D.E.
登録日2018-05-18
公開日2018-10-17
実験手法ELECTRON MICROSCOPY (3.28 Å)
主引用文献Structure of the mammalian TRPM7, a magnesium channel required during embryonic development.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6BWD
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3.7 ANGSTROM CRYOEM STRUCTURE OF TRUNCATED MOUSE TRPM7
分子名称:Transient receptor potential cation channel subfamily M member 7, MAGNESIUM ION, CHOLESTEROL HEMISUCCINATE
著者Zhang, J., Li, Z., Duan, J., Li, J., Hulse, R.E., Santa-Cruz, A., Abiria, S.A., Krapivinsky, G., Clapham, D.E.
登録日2017-12-14
公開日2018-08-15
最終更新日2018-09-05
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Structure of the mammalian TRPM7, a magnesium channel required during embryonic development.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6BWI
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3.7 ANGSTROM CRYOEM STRUCTURE OF FULL LENGTH HUMAN TRPM4
分子名称:Transient receptor potential cation channel subfamily M member 4, SODIUM ION, CHOLESTEROL HEMISUCCINATE, ...
著者Zhang, J., Li, Z., Duan, J., Li, J., Clapham, D.E.
登録日2017-12-15
公開日2018-12-19
最終更新日2019-07-03
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Structure of full-length human TRPM4.
Proc.Natl.Acad.Sci.USA, 115, 2018
3MTS
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CHROMO DOMAIN OF HUMAN HISTONE-LYSINE N-METHYLTRANSFERASE SUV39H1
分子名称:Histone-lysine N-methyltransferase SUV39H1
著者Lam, R., Li, Z., Wang, J., Crombet, L., Walker, J.R., Ouyang, H., Bountra, C., Weigelt, J., Arrowsmith, C.H., Edwards, A.M., Bochkarev, A., Min, J., Structural Genomics Consortium (SGC)
登録日2010-04-30
公開日2010-06-30
最終更新日2017-11-08
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystal Structure of the Human SUV39H1 Chromodomain and Its Recognition of Histone H3K9me2/3.
Plos One, 7, 2012
3Q1J
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CRYSTAL STRUCTURE OF TUDOR DOMAIN 1 OF HUMAN PHD FINGER PROTEIN 20
分子名称:PHD finger protein 20, UNKNOWN ATOM OR ION
著者Tempel, W., Li, Z., Wernimont, A.K., Chao, X., Bian, C., Lam, R., Crombet, L., Bountra, C., Weigelt, J., Arrowsmith, C.H., Edwards, A.M., Min, J., Structural Genomics Consortium (SGC)
登録日2010-12-17
公開日2011-02-09
最終更新日2017-11-08
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Crystal structures of the Tudor domains of human PHF20 reveal novel structural variations on the Royal Family of proteins.
Febs Lett., 586, 2012