Author results

3P20
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CRYSTAL STRUCTURE OF VANADATE BOUND SUBUNIT A OF THE A1AO ATP SYNTHASE
Descriptor:V-type ATP synthase alpha chain, VANADATE ION, ACETIC ACID, ...
Authors:Manimekalai, M.S.S., Kumar, A., Jeyakanthan, J., Gruber, G.
Deposit date:2010-10-01
Release date:2011-03-30
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:The transition-like state and Pi entrance into the catalytic a subunit of the biological engine A-ATP synthase.
J.Mol.Biol., 408, 2011
3QG1
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CRYSTAL STRUCTURE OF P-LOOP G239A MUTANT OF SUBUNIT A OF THE A1AO ATP SYNTHASE
Descriptor:V-type ATP synthase alpha chain, ACETIC ACID, (4S)-2-METHYL-2,4-PENTANEDIOL
Authors:Ragunathan, P., Manimekalai, M.S.S., Kumar, A., Jeyakanthan, J., Gruber, G.
Deposit date:2011-01-24
Release date:2011-10-05
Last modified:2017-08-23
Method:X-RAY DIFFRACTION (2.95 Å)
Cite:Conserved glycine residues in the P-loop of ATP synthases form a doorframe for nucleotide entrance.
J.Mol.Biol., 413, 2011
1BPB
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CRYSTAL STRUCTURE OF RAT DNA POLYMERASE BETA: EVIDENCE FOR A COMMON POLYMERASE MECHANISM
Descriptor:DNA POLYMERASE BETA
Authors:Sawaya, M.R., Pelletier, H., Kumar, A., Wilson, S.H., Kraut, J.
Deposit date:1994-04-12
Release date:1994-06-22
Last modified:2011-11-16
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structure of rat DNA polymerase beta: evidence for a common polymerase mechanism.
Science, 264, 1994
1BPD
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CRYSTAL STRUCTURE OF RAT DNA POLYMERASE BETA: EVIDENCE FOR A COMMON POLYMERASE MECHANISM
Descriptor:DNA POLYMERASE BETA, PHOSPHATE ION
Authors:Sawaya, M.R., Pelletier, H., Kumar, A., Wilson, S.H., Kraut, J.
Deposit date:1994-04-12
Release date:1994-06-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.6 Å)
Cite:Crystal structure of rat DNA polymerase beta: evidence for a common polymerase mechanism.
Science, 264, 1994
1RL4
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PLASMODIUM FALCIPARUM PEPTIDE DEFORMYLASE COMPLEX WITH INHIBITOR
Descriptor:formylmethionine deformylase, COBALT (II) ION, (2R)-2-{[FORMYL(HYDROXY)AMINO]METHYL}HEXANOIC ACID, ...
Authors:Robien, M.A., Nguyen, K.T., Kumar, A., Hirsh, I., Turley, S., Pei, D., Hol, W.G.J.
Deposit date:2003-11-24
Release date:2003-12-09
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.18 Å)
Cite:An improved crystal form of Plasmodium falciparum peptide deformylase.
Protein Sci., 13, 2004
1RQC
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CRYSTALS OF PEPTIDE DEFORMYLASE FROM PLASMODIUM FALCIPARUM WITH TEN SUBUNITS PER ASYMMETRIC UNIT REVEAL CRITICAL CHARACTERISTICS OF THE ACTIVE SITE FOR DRUG DESIGN
Descriptor:formylmethionine deformylase, COBALT (II) ION
Authors:Robien, M.A., Nguyen, K.T., Kumar, A., Hirsh, I., Turley, S., Pei, D., Hol, W.G.
Deposit date:2003-12-04
Release date:2004-01-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:An improved crystal form of Plasmodium falciparum peptide deformylase
Protein Sci., 13, 2004
2BPC
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CRYSTAL STRUCTURE OF RAT DNA POLYMERASE BETA: EVIDENCE FOR A COMMON POLYMERASE MECHANISM
Descriptor:DNA POLYMERASE BETA, MANGANESE (II) ION
Authors:Sawaya, M.R., Pelletier, H., Kumar, A., Wilson, S.H., Kraut, J.
Deposit date:1994-07-08
Release date:1994-08-31
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal structure of rat DNA polymerase beta: evidence for a common polymerase mechanism.
Science, 264, 1994
2BPF
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STRUCTURES OF TERNARY COMPLEXES OF RAT DNA POLYMERASE BETA, A DNA TEMPLATE-PRIMER, AND DDCTP
Descriptor:DNA (5'-D(*GP*GP*GP*CP*GP*CP*CP*G)-3'), DNA (5'-D(*CP*GP*GP*CP*GP*CP*C)-3'), PROTEIN (DNA POLYMERASE BETA (E.C.2.7.7.7)), ...
Authors:Pelletier, H., Sawaya, M.R., Kumar, A., Wilson, S.H., Kraut, J.
Deposit date:1994-05-19
Release date:1994-12-14
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structures of ternary complexes of rat DNA polymerase beta, a DNA template-primer, and ddCTP.
Science, 264, 1994
2BPG
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STRUCTURES OF TERNARY COMPLEXES OF RAT DNA POLYMERASE BETA, A DNA TEMPLATE-PRIMER, AND DDCTP
Descriptor:DNA (5'-D(*GP*GP*GP*CP*GP*CP*CP*G)-3'), DNA (5'-D(*CP*GP*GP*CP*GP*CP*C)-3'), DNA POLYMERASE BETA, ...
Authors:Pelletier, H., Sawaya, M.R., Kumar, A., Wilson, S.H., Kraut, J.
Deposit date:1994-05-19
Release date:1994-08-31
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.6 Å)
Cite:Structures of ternary complexes of rat DNA polymerase beta, a DNA template-primer, and ddCTP.
Science, 264, 1994
3EIU
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A SECOND TRANSIENT POSITION OF ATP ON ITS TRAIL TO THE NUCLEOTIDE-BINDING SITE OF SUBUNIT B OF THE MOTOR PROTEIN A1AO ATP SYNTHASE
Descriptor:V-type ATP synthase beta chain, ADENOSINE-5'-TRIPHOSPHATE, 4-(2-AMINOETHYL)BENZENESULFONYL FLUORIDE
Authors:Manimekalai, S.M.S., Kumar, A., Balakrishna, A.M., Gruber, G.
Deposit date:2008-09-17
Release date:2009-02-10
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (3.43 Å)
Cite:A second transient position of ATP on its trail to the nucleotide-binding site of subunit B of the motor protein A(1)A(O) ATP synthase
J.Struct.Biol., 166, 2009
4JC4
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CRYSTAL STRUCTURE OF PEPTIDYL-TRNA HYDROLASE FROM PSEUDOMONAS AERUGINOSA AT 2.25 ANGSTROM RESOLUTION
Descriptor:Peptidyl-tRNA hydrolase, GLYCEROL
Authors:Singh, A., Kumar, A., Sinha, M., Bhushan, A., Kaur, P., Sharma, S., Arora, A., Singh, T.P.
Deposit date:2013-02-21
Release date:2013-04-03
Last modified:2014-11-12
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Structural and binding studies of peptidyl-tRNA hydrolase from Pseudomonas aeruginosa provide a platform for the structure-based inhibitor design against peptidyl-tRNA hydrolase
Biochem.J., 463, 2014
4QAJ
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CRYSTAL STRUCTURE OF PEPTIDYL-TRNA HYDROLASE FROM PSEUDOMONAS AERUGINOSA AT 1.5 ANGSTROM RESOLUTION
Descriptor:Peptidyl-tRNA hydrolase
Authors:Singh, A., Kumar, A., Gautam, L., Sinha, M., Bhushan, A., Kaur, P., Sharma, S., Arora, A., Singh, T.P.
Deposit date:2014-05-05
Release date:2014-05-28
Last modified:2014-11-12
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Structural and binding studies of peptidyl-tRNA hydrolase from Pseudomonas aeruginosa provide a platform for the structure-based inhibitor design against peptidyl-tRNA hydrolase
Biochem.J., 463, 2014
6HUE
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PARKINS65N
Descriptor:E3 ubiquitin-protein ligase parkin, ZINC ION, SULFATE ION, ...
Authors:McWilliams, T.G., Barini, E., Pohjolan-Pirhonen, R., Brooks, S.P., Singh, F., Burel, S., Balk, K., Kumar, A., Montava-Garriga, L., Prescott, A.R., Hassoun, S.M., Mouton-Liger, F., Ball, G., Hills, R., Knebel, A., Ulusoy, A., Di Monte, D.A., Tamjar, J., Antico, O., Fears, K., Smith, L., Brambilla, R., Palin, E., Valori, M., Eerola-Rautio, J., Tienari, P., Corti, O., Dunnett, S.B., Ganley, I.G., Suomalainen, A., Muqit, M.M.K.
Deposit date:2018-10-07
Release date:2018-10-17
Last modified:2018-11-21
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Phosphorylation of Parkin at serine 65 is essential for its activationin vivo.
Open Biol, 8, 2018
2G15
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STRUCTURAL CHARACTERIZATION OF AUTOINHIBITED C-MET KINASE
Descriptor:activated met oncogene
Authors:Wang, W., Marimuthu, A., Tsai, J., Kumar, A., Krupka, H.I., Zhang, C., Powell, B., Suzuki, Y., Nguyen, H., Tabrizizad, M., Luu, C., West, B.L.
Deposit date:2006-02-13
Release date:2006-03-21
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Structural characterization of autoinhibited c-Met kinase produced by coexpression in bacteria with phosphatase.
Proc.Natl.Acad.Sci.Usa, 103, 2006
2LGJ
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SOLUTION STRUCTURE OF MSPTH
Descriptor:Peptidyl-tRNA hydrolase
Authors:Yadav, R., Pathak, P., Pulavarti, S., Jain, A., Kumar, A., Shukla, V., Arora, A.
Deposit date:2011-07-27
Release date:2012-08-01
Method:SOLUTION NMR
Cite:Solution structure and backbone dynamics of Peptidyl t-RNA hydrolase from Mycobacterium smegmatis
To be Published
3FS3
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CRYSTAL STRUCTURE OF MALARIA PARASITE NUCLEOSOME ASSEMBLY PROTEIN (NAP)
Descriptor:Nucleosome assembly protein 1, putative
Authors:Gill, J., Yogavel, M., Kumar, A., Belrhali, H., Sharma, A.
Deposit date:2009-01-09
Release date:2009-01-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structure of malaria parasite nucleosome assembly protein: distinct modes of protein localization and histone recognition.
J.Biol.Chem., 284, 2009
4B2Z
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STRUCTURE OF OSH6 IN COMPLEX WITH PHOSPHATIDYLSERINE
Descriptor:Oxysterol-binding protein homolog 6, SULFATE ION, O-[(R)-{[(2R)-2,3-bis(octadecanoyloxy)propyl]oxy}(hydroxy)phosphoryl]-L-serine, ...
Authors:Maeda, K., Anand, K., Chiapparino, A., Kumar, A., Poletto, M., Kaksonen, M., Gavin, A.C.
Deposit date:2012-07-19
Release date:2013-06-26
Last modified:2018-12-12
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Interactome Map Uncovers Phosphatidylserine Transport by Oxysterol-Binding Proteins
Nature, 501, 2013
4FNO
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CRYSTAL STRUCTURE OF PEPTIDYL T-RNA HYDROLASE FROM PSEUDOMONAS AERUGINOSA AT 2.2 ANGSTROM RESOLUTION
Descriptor:Peptidyl-tRNA hydrolase, DI(HYDROXYETHYL)ETHER, GLYCEROL
Authors:Singh, A., Kumar, A., Arora, A., Singh, N., Sinha, M., Kaur, P., Sharma, S., Singh, T.P.
Deposit date:2012-06-20
Release date:2012-07-04
Last modified:2014-11-12
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Structural and binding studies of peptidyl-tRNA hydrolase from Pseudomonas aeruginosa provide a platform for the structure-based inhibitor design against peptidyl-tRNA hydrolase
Biochem.J., 463, 2014
4YN6
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STRUCTURAL INSIGHT REVEALS DYNAMICS IN REPEATING R(CAG) TRANSCRIPT FOUND IN HUNTINGTON'S DISEASE (HD) AND SPINOCEREBELLAR ATAXIAS (SCAS)
Descriptor:RNA (5'-R(P*UP*UP*GP*GP*GP*CP*CP*AP*GP*CP*AP*GP*CP*AP*GP*GP*UP*CP*C)-3'), PHOSPHATE ION
Authors:Tawani, A., Kumar, A.
Deposit date:2015-03-09
Release date:2015-04-22
Last modified:2015-09-02
Method:X-RAY DIFFRACTION (2.301 Å)
Cite:Structural Insights Reveal the Dynamics of the Repeating r(CAG) Transcript Found in Huntington's Disease (HD) and Spinocerebellar Ataxias (SCAs)
Plos One, 10, 2015
5CAD
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CRYSTAL STRUCTURE OF THE VICILIN FROM SOLANUM MELONGENA REVEALED EXISTENCE OF DIFFERENT ANIONIC LIGANDS IN STRUCTURALLY SIMILAR POCKETS
Descriptor:SM80.1 Vicilin, MAGNESIUM ION, ACETATE ION, ...
Authors:Jain, A., Kumar, A., Salunke, D.M.
Deposit date:2015-06-29
Release date:2016-04-06
Method:X-RAY DIFFRACTION (1.49 Å)
Cite:Crystal structure of the vicilin from Solanum melongena reveals existence of different anionic ligands in structurally similar pockets
Sci Rep, 6, 2016
5HWI
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CRYSTAL STRUCTURE OF SELENOMETHIONINE LABELLED GAMA GLUTAMYL CYCLOTRANSFEREASE SPECIFIC TO GLUTATHIONE FROM YEAST
Descriptor:Glutathione-specific gamma-glutamylcyclotransferase, SUCCINIC ACID, GLYCEROL
Authors:Kaur, A., Gautam, R., Srivastava, R., Chandel, A., Kumar, A., Karthikeyan, S., Bachhawat, A.K.
Deposit date:2016-01-29
Release date:2016-12-14
Last modified:2017-01-25
Method:X-RAY DIFFRACTION (1.755 Å)
Cite:ChaC2, an Enzyme for Slow Turnover of Cytosolic Glutathione
J. Biol. Chem., 292, 2017
5HWK
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CRYSTAL STRUCTURE OF GAMA GLUTAMYL CYCLOTRANSFEREASE SPECIFIC TO GLUTATHIONE FROM YEAST
Descriptor:Glutathione-specific gamma-glutamylcyclotransferase, BENZOIC ACID, PHOSPHATE ION
Authors:Kaur, A., Gautam, R., Srivastava, R., Chandel, A., Kumar, A., Karthikeyan, S., Bachhawat, A.K.
Deposit date:2016-01-29
Release date:2016-12-14
Last modified:2017-01-25
Method:X-RAY DIFFRACTION (1.344 Å)
Cite:ChaC2, an Enzyme for Slow Turnover of Cytosolic Glutathione
J. Biol. Chem., 292, 2017
5IQY
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STRUCTURE OF APO-DEHYDROASCORBATE REDUCTASE FROM PENNISETUM GLAUCUM PHASED BY IODIDE-SAD METHOD
Descriptor:Dehydroascorbate reductase, IODIDE ION
Authors:Das, B.K., Kumar, A., Manidola, P., Arockiasamy, A.
Deposit date:2016-03-11
Release date:2016-05-04
Last modified:2017-10-04
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Non-native ligands define the active site of Pennisetum glaucum (L.) R. Br dehydroascorbate reductase
Biochem.Biophys.Res.Commun., 473, 2016
5XYL
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SOLUTION STRUCTURE OF SKP1 FROM HOMO SAPIENS
Descriptor:S-phase kinase-associated protein 1
Authors:Shukla, V.K., Kachariya, N.N., Bhattacharya, A., Dantu, S.C., Kumar, A.
Deposit date:2017-07-09
Release date:2018-07-11
Method:SOLUTION NMR
Cite:Structural and dynamics insight of the recognition of Fbox protein by Skp1
To Be Published
6EOJ
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POLYA POLYMERASE MODULE OF THE CLEAVAGE AND POLYADENYLATION FACTOR (CPF) FROM SACCHAROMYCES CEREVISIAE
Descriptor:Protein CFT1, mRNA 3'-end-processing protein YTH1, Polyadenylation factor subunit 2,Polyadenylation factor subunit 2, ...
Authors:Casanal, A., Kumar, A., Hill, C.H., Emsley, P., Passmore, L.
Deposit date:2017-10-09
Release date:2017-11-15
Last modified:2018-01-31
Method:ELECTRON MICROSCOPY (3.55 Å)
Cite:Architecture of eukaryotic mRNA 3'-end processing machinery.
Science, 358, 2017