1K4R
 
 | | Structure of Dengue Virus | | Descriptor: | MAJOR ENVELOPE PROTEIN E | | Authors: | Kuhn, R.J, Zhang, W, Rossmann, M.G, Pletnev, S.V, Corver, J, Lenches, E, Jones, C.T, Mukhopadhyay, S, Chipman, P.R, Strauss, E.G, Baker, T.S, Strauss, J.H. | | Deposit date: | 2001-10-08 | | Release date: | 2002-03-13 | | Last modified: | 2018-07-18 | | Method: | ELECTRON MICROSCOPY (24 Å) | | Cite: | Structure of dengue virus: implications for flavivirus organization, maturation, and fusion.
Cell(Cambridge,Mass.), 108, 2002
|
|
1DGI
 | | Cryo-EM structure of human poliovirus(serotype 1)complexed with three domain CD155 | | Descriptor: | POLIOVIRUS RECEPTOR, VP1, VP2, ... | | Authors: | He, Y, Bowman, V.D, Mueller, S, Bator, C.M, Bella, J, Peng, X, Baker, T.S, Wimmer, E, Kuhn, R.J, Rossmann, M.G. | | Deposit date: | 1999-11-24 | | Release date: | 2000-01-24 | | Last modified: | 2024-02-07 | | Method: | ELECTRON MICROSCOPY (22 Å) | | Cite: | Interaction of the poliovirus receptor with poliovirus.
Proc.Natl.Acad.Sci.USA, 97, 2000
|
|
8FE4
 | | Structure of dengue virus (DENV2) in complex with prM13, an anti-PrM monoclonal antibody | | Descriptor: | Envelope protein E, prM protein, prM13 Fab Heavy Chain, ... | | Authors: | Dowd, A.D, Sirohi, D, Speer, S, Mukherjee, S, Govero, J, Aleshnick, M, Larman, B, Sukupolvi-Petty, S, Sevvana, M, Miller, A.S, Klose, T, Zheng, A, Kielian, M, Kuhn, R.J, Diamond, M.S, Pierson, T.C. | | Deposit date: | 2022-12-05 | | Release date: | 2023-02-01 | | Last modified: | 2023-04-05 | | Method: | ELECTRON MICROSCOPY (9.8 Å) | | Cite: | prM-reactive antibodies reveal a role for partially mature virions in dengue virus pathogenesis.
Proc.Natl.Acad.Sci.USA, 120, 2023
|
|
8FE3
 | | Structure of dengue virus (DENV2) in complex with prM12, an anti-PrM monoclonal antibody | | Descriptor: | Envelope protein E, prM protein, prM12 Fab Heavy Chain, ... | | Authors: | Dowd, A.D, Sirohi, D, Speer, S, Mukherjee, S, Govero, J, Aleshnick, M, Larman, B, Sukupolvi-Petty, S, Sevvana, M, Miller, A.S, Klose, T, Zheng, A, Kielian, M, Kuhn, R.J, Diamond, M.S, Pierson, T.C. | | Deposit date: | 2022-12-05 | | Release date: | 2023-02-01 | | Last modified: | 2023-04-05 | | Method: | ELECTRON MICROSCOPY (10.2 Å) | | Cite: | prM-reactive antibodies reveal a role for partially mature virions in dengue virus pathogenesis.
Proc.Natl.Acad.Sci.USA, 120, 2023
|
|
6CO8
 | | Structure of Zika virus at a resolution of 3.1 Angstrom | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, E protein, M protein | | Authors: | Sevvana, M, Long, F, Miller, A.J, Klose, T, Buda, G, Sun, L, Kuhn, R.J, Rossmann, M.R. | | Deposit date: | 2018-03-12 | | Release date: | 2018-07-04 | | Last modified: | 2020-07-29 | | Method: | ELECTRON MICROSCOPY (3.1 Å) | | Cite: | Refinement and Analysis of the Mature Zika Virus Cryo-EM Structure at 3.1 angstrom Resolution.
Structure, 26, 2018
|
|
7T17
 | |
4WM7
 | | Crystal Structure of Human Enterovirus D68 in Complex with Pleconaril | | Descriptor: | 3-{3,5-DIMETHYL-4-[3-(3-METHYL-ISOXAZOL-5-YL)-PROPOXY]-PHENYL}-5-TRIFLUOROMETHYL-[1,2,4]OXADIAZOLE, VP1, VP2, ... | | Authors: | Liu, Y, Sheng, J, Fokine, A, Meng, G, Long, F, Kuhn, R.J, Rossmann, M.G. | | Deposit date: | 2014-10-08 | | Release date: | 2015-01-14 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (2.32 Å) | | Cite: | Virus structure. Structure and inhibition of EV-D68, a virus that causes respiratory illness in children.
Science, 347, 2015
|
|
4WM8
 | | Crystal Structure of Human Enterovirus D68 | | Descriptor: | DECANOIC ACID, VP1, VP2, ... | | Authors: | Liu, Y, Sheng, J, Fokine, A, Meng, G, Long, F, Kuhn, R.J, Rossmann, M.G. | | Deposit date: | 2014-10-08 | | Release date: | 2015-01-14 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Virus structure. Structure and inhibition of EV-D68, a virus that causes respiratory illness in children.
Science, 347, 2015
|
|
5U4W
 | | Cryo-EM Structure of Immature Zika Virus | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, E protein, M protein, ... | | Authors: | Mangala Prasad, V, Miller, A.S, Klose, T, Sirohi, D, Buda, G, Jiang, W, Kuhn, R.J, Rossmann, M.G. | | Deposit date: | 2016-12-06 | | Release date: | 2017-01-11 | | Last modified: | 2020-07-29 | | Method: | ELECTRON MICROSCOPY (9.1 Å) | | Cite: | Structure of the immature Zika virus at 9 angstrom resolution.
Nat. Struct. Mol. Biol., 24, 2017
|
|
5UHY
 | | A Human Antibody Against Zika Virus Crosslinks the E Protein to Prevent Infection | | Descriptor: | ZV67 Fab chain 1, ZV67 Fab chain 2, envelope protein | | Authors: | Hasan, S.S, Miller, A, Sapparapu, G, Fernandez, E, Klose, T, Long, F, Fokine, A, Porta, J.C, Jiang, W, Diamond, M.S, Crowe Jr, J.E, Kuhn, R.J, Rossmann, M.G. | | Deposit date: | 2017-01-12 | | Release date: | 2017-03-29 | | Last modified: | 2019-11-27 | | Method: | ELECTRON MICROSCOPY (6.2 Å) | | Cite: | A human antibody against Zika virus crosslinks the E protein to prevent infection.
Nat Commun, 8, 2017
|
|
4UOM
 | | Electron Cryo-microscopy of Venezuelan Equine Encephalitis Virus TC- 83 in complex with neutralizing antibody Fab F5 | | Descriptor: | FAB FRAGMENT HEAVY CHAIN, FAB FRAGMENT LIGHT CHAIN | | Authors: | Porta, J, Jose, J, Roehrig, J.T, Blair, C.D, Kuhn, R.J, Rossmann, M.G. | | Deposit date: | 2014-06-05 | | Release date: | 2014-10-15 | | Last modified: | 2017-08-23 | | Method: | ELECTRON MICROSCOPY (17 Å) | | Cite: | Locking and Blocking the Viral Landscape of an Alphavirus with Neutralizing Antibodies.
J.Virol., 88, 2014
|
|
4UOK
 | | Electron Cryo-microscopy of Venezuelan Equine Encephalitis Virus TC-83 in complex with neutralizing antibody Fab 3B4C-4 | | Descriptor: | FAB FRAGMENT HEAVY CHAIN, FAB FRAGMENT LIGHT CHAIN | | Authors: | Porta, J, Jose, J, Roehrig, J.T, Blair, C.D, Kuhn, R.J, Rossmann, M.G. | | Deposit date: | 2014-06-04 | | Release date: | 2014-09-17 | | Last modified: | 2019-05-29 | | Method: | ELECTRON MICROSCOPY (18 Å) | | Cite: | Locking and blocking the viral landscape of an alphavirus with neutralizing antibodies.
J.Virol., 88, 2014
|
|
7TAG
 | | Cryo-EM structure of Human Enterovirus D68 US/MO/14-18947 strain virion in complex with pleconaril | | Descriptor: | 3-{3,5-DIMETHYL-4-[3-(3-METHYL-ISOXAZOL-5-YL)-PROPOXY]-PHENYL}-5-TRIFLUOROMETHYL-[1,2,4]OXADIAZOLE, viral protein 1, viral protein 2, ... | | Authors: | Fu, J, Klose, T, Kuhn, R.J, Center for Structural Genomics of Infectious Diseases (CSGID) | | Deposit date: | 2021-12-20 | | Release date: | 2023-01-25 | | Method: | ELECTRON MICROSCOPY (2.7 Å) | | Cite: | Isoxazole-3-Carboxamide Derivatives of Pleconaril Destabilize the Viral Capsid of Enterovirus-D68
To Be Published
|
|
7TAH
 | |
7TAJ
 | |
7TAF
 | | Cryo-EM structure of Human Enterovirus D68 US/MO/14-18947 strain virion in complex with inhibitor 11526092 | | Descriptor: | N,N-dimethyl-5-(3-{2-methyl-4-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]phenoxy}propyl)-1,2-oxazole-3-carboxamide, viral protein 1, viral protein 2, ... | | Authors: | Fu, J, Klose, T, Kuhn, R.J, Center for Structural Genomics of Infectious Diseases (CSGID) | | Deposit date: | 2021-12-20 | | Release date: | 2023-01-25 | | Method: | ELECTRON MICROSCOPY (2 Å) | | Cite: | Isoxazole-3-Carboxamide Derivatives of Pleconaril Destabilize the Viral Capsid of Enterovirus-D68
To Be Published
|
|
7T9P
 | |
7N69
 | |
7N6A
 | |
7V0P
 | | Cryo-EM structure of SINV/EEEV in complex with Fab fragment of a potently neutralizing human antibody IgG-106 | | Descriptor: | IgG 106 Fab heavy chain, IgG 106 Fab light chain, Spike glycoprotein E1, ... | | Authors: | Bandyopadhyay, A, Klose, T, Kuhn, R.J. | | Deposit date: | 2022-05-10 | | Release date: | 2023-04-05 | | Last modified: | 2024-02-21 | | Method: | ELECTRON MICROSCOPY (5.2 Å) | | Cite: | Structural constraints link differences in neutralization potency of human anti-Eastern equine encephalitis virus monoclonal antibodies.
Proc.Natl.Acad.Sci.USA, 120, 2023
|
|
7V0N
 | | Cryo-EM structure of SINV/EEEV in complex with Fab fragment of a moderately/weakly neutralizing human antibody IgG-21 | | Descriptor: | IgG 21 Fab heavy chain, IgG 21 Fab light chain, Spike glycoprotein E1, ... | | Authors: | Bandyopadhyay, A, Klose, T, Kuhn, R.J. | | Deposit date: | 2022-05-10 | | Release date: | 2023-04-05 | | Last modified: | 2024-02-21 | | Method: | ELECTRON MICROSCOPY (5.9 Å) | | Cite: | Structural constraints link differences in neutralization potency of human anti-Eastern equine encephalitis virus monoclonal antibodies.
Proc.Natl.Acad.Sci.USA, 120, 2023
|
|
7V0O
 | | Cryo-EM structure of SINV/EEEV in complex with Fab fragment of a moderately/weakly neutralizing human antibody IgG-94 | | Descriptor: | IgG 94 Fab heavy chain, IgG 94 Fab light chain, Spike glycoprotein E1, ... | | Authors: | Bandyopadhyay, A, Klose, T, Kuhn, R.J. | | Deposit date: | 2022-05-10 | | Release date: | 2023-04-05 | | Last modified: | 2024-02-21 | | Method: | ELECTRON MICROSCOPY (6.6 Å) | | Cite: | Structural constraints link differences in neutralization potency of human anti-Eastern equine encephalitis virus monoclonal antibodies.
Proc.Natl.Acad.Sci.USA, 120, 2023
|
|
2SNW
 | | SINDBIS VIRUS CAPSID PROTEIN, TYPE3 CRYSTAL FORM | | Descriptor: | COAT PROTEIN C | | Authors: | Choi, H.-K, Lee, S, Zhang, Y.-P, Mckinney, B.R, Wengler, G, Rossmann, M.G, Kuhn, R.J. | | Deposit date: | 1998-02-17 | | Release date: | 1998-04-08 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Structural analysis of Sindbis virus capsid mutants involving assembly and catalysis.
J.Mol.Biol., 262, 1996
|
|
2B6B
 | | Cryo EM structure of Dengue complexed with CRD of DC-SIGN | | Descriptor: | CD209 antigen, envelope glycoprotein | | Authors: | Pokidysheva, E, Zhang, Y, Battisti, A.J, Bator-Kelly, C.M, Chipman, P.R, Gregorio, G, Hendrickson, W.A, Kuhn, R.J, Rossmann, M.G. | | Deposit date: | 2005-09-30 | | Release date: | 2006-03-07 | | Last modified: | 2024-02-14 | | Method: | ELECTRON MICROSCOPY (25 Å) | | Cite: | Cryo-EM reconstruction of dengue virus in complex with the carbohydrate recognition domain of DC-SIGN
Cell(Cambridge,Mass.), 124, 2006
|
|
3IYA
 | | Association of the pr peptides with dengue virus blocks membrane fusion at acidic pH | | Descriptor: | Envelope protein, prM protein | | Authors: | Yu, I, Holdaway, H.A, Chipman, P.R, Kuhn, R.J, Rossmann, M.G, Chen, J. | | Deposit date: | 2009-06-01 | | Release date: | 2010-04-14 | | Last modified: | 2024-02-21 | | Method: | ELECTRON MICROSCOPY (22 Å) | | Cite: | Association of the pr peptides with dengue virus at acidic pH blocks membrane fusion.
J.Virol., 83, 2009
|
|
