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8T5X
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BU of 8t5x by Molmil
Probing the dissociation pathway of a kinetically labile transthyretin mutant (A25T)
Descriptor: Transthyretin
Authors:Ferguson, J.A, Sun, X, Leach, B.I, Stanfield, R.L, Dyson, H.J, Wright, P.E.
Deposit date:2023-06-14
Release date:2023-08-02
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.63 Å)
Cite:Probing the Dissociation Pathway of a Kinetically Labile Transthyretin Mutant.
J.Am.Chem.Soc., 146, 2024
6WLH
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BU of 6wlh by Molmil
RNA complex of WT1 zinc finger transcription factor
Descriptor: RNA (29-MER), Wilms tumor protein, ZINC ION
Authors:Wright, P.E, Dyson, H.J.
Deposit date:2020-04-20
Release date:2021-03-03
Method:SOLUTION NMR
Cite:RNA Binding by the KTS Splice Variants of Wilms' Tumor Suppressor Protein WT1.
Biochemistry, 59, 2020
7LVS
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BU of 7lvs by Molmil
The CBP TAZ1 Domain in Complex with a CITED2-HIF-1-Alpha Fusion Peptide
Descriptor: Cbp/p300-interacting transactivator 2,Hypoxia-inducible factor 1-alpha, Histone lysine acetyltransferase CREBBP, ZINC ION
Authors:Appling, F.D, Berlow, R.B, Stanfield, R.L, Dyson, H.J, Wright, P.E.
Deposit date:2021-02-26
Release date:2021-07-28
Last modified:2021-12-15
Method:X-RAY DIFFRACTION (2.02 Å)
Cite:The molecular basis of allostery in a facilitated dissociation process.
Structure, 29, 2021
6UNA
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BU of 6una by Molmil
Crystal structure of inactive p38gamma
Descriptor: GLYCEROL, Mitogen-activated protein kinase 12, SULFATE ION
Authors:Aoto, P.C, Stanfield, R.L, Wilson, I.A, Dyson, H.J, Wright, P.E.
Deposit date:2019-10-11
Release date:2019-12-18
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.554 Å)
Cite:A Dynamic Switch in Inactive p38 gamma Leads to an Excited State on the Pathway to an Active Kinase.
Biochemistry, 58, 2019
6V8U
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BU of 6v8u by Molmil
Kaiso (ZBTB33) zinc finger DNA binding domain in complex with a modified Kaiso binding sequence (KBS)
Descriptor: CHLORIDE ION, DNA (5'-D(*CP*GP*TP*TP*AP*TP*TP*GP*GP*CP*AP*CP*GP*AP*AP*GP*CP*A)-3'), DNA (5'-D(*TP*GP*CP*TP*TP*CP*GP*TP*GP*CP*CP*AP*AP*TP*AP*AP*CP*G)-3'), ...
Authors:Nikolova, E.N, Stanfield, R.L, Dyson, H.J, Wright, P.E.
Deposit date:2019-12-12
Release date:2020-04-15
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.103 Å)
Cite:A Conformational Switch in the Zinc Finger Protein Kaiso Mediates Differential Readout of Specific and Methylated DNA Sequences.
Biochemistry, 59, 2020
1XOB
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BU of 1xob by Molmil
THIOREDOXIN (REDUCED DITHIO FORM), NMR, 20 STRUCTURES
Descriptor: THIOREDOXIN
Authors:Jeng, M.-F, Campbell, A.P, Begley, T, Holmgren, A, Case, D.A, Wright, P.E, Dyson, H.J.
Deposit date:1995-11-28
Release date:1996-06-10
Last modified:2017-11-29
Method:SOLUTION NMR
Cite:High-resolution solution structures of oxidized and reduced Escherichia coli thioredoxin.
Structure, 2, 1994
1XOA
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BU of 1xoa by Molmil
THIOREDOXIN (OXIDIZED DISULFIDE FORM), NMR, 20 STRUCTURES
Descriptor: THIOREDOXIN
Authors:Jeng, M.-F, Campbell, A.P, Begley, T, Holmgren, A, Case, D.A, Wright, P.E, Dyson, H.J.
Deposit date:1995-11-28
Release date:1996-06-10
Last modified:2017-11-29
Method:SOLUTION NMR
Cite:High-resolution solution structures of oxidized and reduced Escherichia coli thioredoxin.
Structure, 2, 1994
1CUR
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BU of 1cur by Molmil
REDUCED RUSTICYANIN, NMR
Descriptor: COPPER (II) ION, CU(I) RUSTICYANIN
Authors:Botuyan, M.V, Dyson, H.J.
Deposit date:1996-04-19
Release date:1996-11-08
Last modified:2022-02-16
Method:SOLUTION NMR
Cite:NMR solution structure of Cu(I) rusticyanin from Thiobacillus ferrooxidans: structural basis for the extreme acid stability and redox potential.
J.Mol.Biol., 263, 1996
5HP0
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BU of 5hp0 by Molmil
Solution Structure of TAZ2-p53AD2
Descriptor: CREB-binding protein,Cellular tumor antigen p53 fusion protein, ZINC ION
Authors:Krois, A.S, Ferreon, J.C, Martinez-Yamout, M.A, Dyson, H.J, Wright, P.E.
Deposit date:2016-01-19
Release date:2016-03-16
Last modified:2019-12-04
Method:SOLUTION NMR
Cite:Recognition of the disordered p53 transactivation domain by the transcriptional adapter zinc finger domains of CREB-binding protein.
Proc.Natl.Acad.Sci.USA, 113, 2016
5HPD
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BU of 5hpd by Molmil
Solution Structure of TAZ2-p53TAD
Descriptor: CREB-binding protein,Cellular tumor antigen p53 fusion protein, ZINC ION
Authors:Krois, A.S, Ferreon, J.C, Martinez-Yamout, M.A, Dyson, H.J, Wright, P.E.
Deposit date:2016-01-20
Release date:2016-03-16
Last modified:2019-12-04
Method:SOLUTION NMR
Cite:Recognition of the disordered p53 transactivation domain by the transcriptional adapter zinc finger domains of CREB-binding protein.
Proc.Natl.Acad.Sci.USA, 113, 2016
5HOU
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BU of 5hou by Molmil
Solution Structure of p53TAD-TAZ1
Descriptor: Cellular tumor antigen p53,CREB-binding protein fusion protein, ZINC ION
Authors:Krois, A.S, Ferreon, J.C, Martinez-Yamout, M.A, Dyson, H.J, Wright, P.E.
Deposit date:2016-01-19
Release date:2016-03-16
Last modified:2019-12-04
Method:SOLUTION NMR
Cite:Recognition of the disordered p53 transactivation domain by the transcriptional adapter zinc finger domains of CREB-binding protein.
Proc.Natl.Acad.Sci.USA, 113, 2016
6DFA
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BU of 6dfa by Molmil
Kaiso (ZBTB33) E535A zinc finger DNA binding domain in complex with the specific Kaiso binding sequence (KBS)
Descriptor: CHLORIDE ION, DNA (5'-D(*CP*GP*TP*TP*AP*TP*TP*GP*GP*CP*AP*GP*GP*AP*AP*GP*CP*A)-3'), DNA (5'-D(*TP*GP*CP*TP*TP*CP*CP*TP*GP*CP*CP*AP*AP*TP*AP*AP*CP*G)-3'), ...
Authors:Nikolova, E.N, Stanfield, R.L, Dyson, H.J, Wright, P.E.
Deposit date:2018-05-14
Release date:2019-05-22
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.908 Å)
Cite:A conformational switch in the zinc finger protein Kaiso mediates differential readout of specific and methylated DNA sequences.
Biochemistry, 2020
6DF9
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BU of 6df9 by Molmil
Kaiso (ZBTB33) E535Q zinc finger DNA binding domain in complex with the specific Kaiso binding sequence (KBS)
Descriptor: CHLORIDE ION, DNA (5'-D(*CP*GP*TP*TP*AP*TP*TP*GP*GP*CP*AP*GP*GP*AP*AP*GP*CP*A)-3'), DNA (5'-D(*TP*GP*CP*TP*TP*CP*CP*TP*GP*CP*CP*AP*AP*TP*AP*AP*CP*G)-3'), ...
Authors:Nikolova, E.N, Stanfield, R.L, Dyson, H.J, Wright, P.E.
Deposit date:2018-05-14
Release date:2019-05-22
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.319 Å)
Cite:A conformational switch in the zinc finger protein Kaiso mediates differential readout of specific and methylated DNA sequences.
Biochemistry, 2020
6DF8
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BU of 6df8 by Molmil
Kaiso (ZBTB33) zinc finger DNA binding domain in complex with the specific Kaiso binding sequence (KBS), pH 6.5
Descriptor: CHLORIDE ION, DNA (5'-D(*CP*GP*TP*TP*AP*TP*TP*GP*GP*CP*AP*GP*GP*AP*AP*GP*CP*A)-3'), DNA (5'-D(*TP*GP*CP*TP*TP*CP*CP*TP*GP*CP*CP*AP*AP*TP*AP*AP*CP*G)-3'), ...
Authors:Nikolova, E.N, Stanfield, R.L, Dyson, H.J, Wright, P.E.
Deposit date:2018-05-14
Release date:2019-05-22
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.536 Å)
Cite:A conformational switch in the zinc finger protein Kaiso mediates differential readout of specific and methylated DNA sequences.
Biochemistry, 2020
6DF5
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BU of 6df5 by Molmil
Kaiso (ZBTB33) zinc finger DNA binding domain in complex with the specific Kaiso binding sequence (KBS)
Descriptor: CHLORIDE ION, DNA (5'-D(*CP*GP*TP*TP*AP*TP*TP*GP*GP*CP*AP*GP*GP*AP*AP*GP*CP*A)-3'), DNA (5'-D(*TP*GP*CP*TP*TP*CP*CP*TP*GP*CP*CP*AP*AP*TP*AP*AP*CP*G)-3'), ...
Authors:Nikolova, E.N, Stanfield, R.L, Dyson, H.J, Wright, P.E.
Deposit date:2018-05-14
Release date:2019-05-22
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.819 Å)
Cite:A conformational switch in the zinc finger protein Kaiso mediates differential readout of specific and methylated DNA sequences.
Biochemistry, 2020
6DFB
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BU of 6dfb by Molmil
Kaiso (ZBTB33) K539A zinc finger DNA binding domain in complex with the specific Kaiso binding sequence (KBS)
Descriptor: CHLORIDE ION, DNA (5'-D(*CP*GP*TP*TP*AP*TP*TP*GP*GP*CP*AP*GP*GP*AP*AP*GP*CP*A)-3'), DNA (5'-D(*TP*GP*CP*TP*TP*CP*CP*TP*GP*CP*CP*AP*AP*TP*AP*AP*CP*G)-3'), ...
Authors:Nikolova, E.N, Stanfield, R.L, Dyson, H.J, Wright, P.E.
Deposit date:2018-05-14
Release date:2019-05-22
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.66 Å)
Cite:A conformational switch in the zinc finger protein Kaiso mediates differential readout of specific and methylated DNA sequences.
Biochemistry, 2020
6DFC
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BU of 6dfc by Molmil
Kaiso (ZBTB33) zinc finger DNA binding domain in complex with the specific Kaiso binding sequence (KBS) with a T-to-U substitution
Descriptor: CHLORIDE ION, DNA (5'-D(*CP*GP*TP*TP*AP*TP*TP*GP*GP*CP*AP*AP*GP*AP*AP*GP*CP*A)-3'), DNA (5'-D(*TP*GP*CP*TP*TP*CP*UP*TP*GP*CP*CP*AP*AP*TP*AP*AP*CP*G)-3'), ...
Authors:Nikolova, E.N, Stanfield, R.L, Dyson, H.J, Wright, P.E.
Deposit date:2018-05-14
Release date:2019-05-22
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:A conformational switch in the zinc finger protein Kaiso mediates differential readout of specific and methylated DNA sequences.
Biochemistry, 2020
5U7G
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BU of 5u7g by Molmil
Crystal Structure of the Catalytic Core of CBP
Descriptor: CREB-binding protein, ZINC ION
Authors:Park, S, Stanfield, R.L, Martinez-Yamout, M.M, Dyson, H.J, Wilson, I.A, Wright, P.E.
Deposit date:2016-12-12
Release date:2017-06-21
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.401 Å)
Cite:Role of the CBP catalytic core in intramolecular SUMOylation and control of histone H3 acetylation.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5U6L
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BU of 5u6l by Molmil
Solution structure of the zinc fingers 3 and 4 of MBNL1
Descriptor: Muscleblind-like protein 1, ZINC ION
Authors:Phukan, P.D, Park, S, Martinez-Yamout, M.M, Zeeb, M, Dyson, H.J, Wright, P.E.
Deposit date:2016-12-08
Release date:2017-08-02
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Structural Basis for Interaction of the Tandem Zinc Finger Domains of Human Muscleblind with Cognate RNA from Human Cardiac Troponin T.
Biochemistry, 56, 2017
5U6H
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BU of 5u6h by Molmil
Solution structure of the zinc fingers 1 and 2 of MBNL1
Descriptor: Muscleblind-like protein 1, ZINC ION
Authors:Phukan, P.D, Park, S, Martinez-Yamout, M.M, Zeeb, M, Dyson, H.J, Wright, P.E.
Deposit date:2016-12-08
Release date:2017-08-02
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Structural Basis for Interaction of the Tandem Zinc Finger Domains of Human Muscleblind with Cognate RNA from Human Cardiac Troponin T.
Biochemistry, 56, 2017
5U9B
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BU of 5u9b by Molmil
Solution structure of the zinc fingers 1 and 2 of MBNL1 in complex with human cardiac troponin T pre-mRNA
Descriptor: Muscleblind-like protein 1, RNA (5'-R(P*GP*UP*CP*UP*CP*GP*CP*UP*UP*UP*UP*CP*CP*CP*C)-3'), ZINC ION
Authors:Phukan, P.D, Park, S, Martinez-Yamout, M.M, Zeeb, M, Dyson, H.J, Wright, P.E.
Deposit date:2016-12-15
Release date:2017-08-02
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Structural Basis for Interaction of the Tandem Zinc Finger Domains of Human Muscleblind with Cognate RNA from Human Cardiac Troponin T.
Biochemistry, 56, 2017
5VMU
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BU of 5vmu by Molmil
Kaiso (ZBTB33) zinc finger DNA binding domain in complex with a double CpG-methylated DNA resembling the specific Kaiso binding sequence (KBS)
Descriptor: CHLORIDE ION, DNA (5'-D(*CP*GP*TP*TP*AP*TP*TP*(5CM)P*GP*(5CM)P*GP*GP*GP*AP*AP*GP*CP*A)-3'), DNA (5'-D(*TP*GP*CP*TP*TP*CP*CP*(5CM)P*GP*(5CM)P*GP*AP*AP*TP*AP*AP*CP*G)-3'), ...
Authors:Nikolova, E.N, Stanfield, R.L, Martinez-Yamout, M.A, Dyson, H.J, Wright, P.E.
Deposit date:2017-04-28
Release date:2018-04-04
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.346 Å)
Cite:CH···O Hydrogen Bonds Mediate Highly Specific Recognition of Methylated CpG Sites by the Zinc Finger Protein Kaiso.
Biochemistry, 57, 2018
5VMZ
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BU of 5vmz by Molmil
Kaiso (ZBTB33) E535Q mutant zinc finger DNA binding domain in complex with a double CpG-methylated DNA resembling the specific Kaiso binding sequence (KBS)
Descriptor: CHLORIDE ION, DNA (5'-D(*CP*GP*TP*TP*AP*TP*TP*(5CM)P*GP*(5CM)P*GP*GP*GP*AP*AP*GP*CP*A)-3'), DNA (5'-D(*TP*GP*CP*TP*TP*CP*CP*(5CM)P*GP*(5CM)P*GP*AP*AP*TP*AP*AP*CP*G)-3'), ...
Authors:Nikolova, E.N, Stanfield, R.L, Martinez-Yamout, M.A, Dyson, H.J, Wright, P.E.
Deposit date:2017-04-28
Release date:2018-04-04
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.319 Å)
Cite:CH···O Hydrogen Bonds Mediate Highly Specific Recognition of Methylated CpG Sites by the Zinc Finger Protein Kaiso.
Biochemistry, 57, 2018
5VMV
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BU of 5vmv by Molmil
Kaiso (ZBTB33) zinc finger DNA binding domain in complex with its double CpG-methylated DNA consensus binding site
Descriptor: CHLORIDE ION, DNA (5'-D(*TP*GP*CP*TP*TP*CP*TP*(5CM)P*GP*(5CM)P*GP*AP*GP*AP*AP*GP*CP*A)-3'), Transcriptional regulator Kaiso, ...
Authors:Nikolova, E.N, Stanfield, R.L, Martinez-Yamout, M.A, Dyson, H.J, Wright, P.E.
Deposit date:2017-04-28
Release date:2018-04-04
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.313 Å)
Cite:CH···O Hydrogen Bonds Mediate Highly Specific Recognition of Methylated CpG Sites by the Zinc Finger Protein Kaiso.
Biochemistry, 57, 2018
5VMX
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BU of 5vmx by Molmil
Kaiso (ZBTB33) zinc finger DNA binding domain in complex with a hemi CpG-methylated DNA resembling the specific Kaiso binding sequence (KBS)
Descriptor: CHLORIDE ION, DNA (5'-D(*CP*GP*TP*TP*AP*TP*TP*CP*GP*CP*GP*GP*GP*AP*AP*GP*CP*A)-3'), DNA (5'-D(*TP*GP*CP*TP*TP*CP*CP*(5CM)P*GP*(5CM)P*GP*AP*AP*TP*AP*AP*CP*G)-3'), ...
Authors:Nikolova, E.N, Stanfield, R.L, Martinez-Yamout, M.A, Dyson, H.J, Wright, P.E.
Deposit date:2017-04-28
Release date:2018-04-04
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:CH···O Hydrogen Bonds Mediate Highly Specific Recognition of Methylated CpG Sites by the Zinc Finger Protein Kaiso.
Biochemistry, 57, 2018

 

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