Author results

1IBM
  • Download 1ibm
  • View 1ibm
Molmil generated image of 1ibm
STRUCTURE OF THE THERMUS THERMOPHILUS 30S RIBOSOMAL SUBUNIT IN COMPLEX WITH A MESSENGER RNA FRAGMENT AND COGNATE TRANSFER RNA ANTICODON STEM-LOOP BOUND AT THE A SITE
Descriptor:16S RIBOSOMAL RNA, P-SITE MESSENGER RNA FRAGMENT, ANTICODON STEM-LOOP OF PHENYLALANINE TRANSFER RNA, ...
Authors:Ogle, J.M., Brodersen, D.E., Clemons Jr., W.M., Tarry, M.J., Carter, A.P., Ramakrishnan, V.
Deposit date:2001-03-28
Release date:2001-05-04
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.31 Å)
Cite:Recognition of cognate transfer RNA by the 30S ribosomal subunit.
Science, 292, 2001
5LZS
  • Download 5lzs
  • View 5lzs
Molmil generated image of 5lzs
STRUCTURE OF THE MAMMALIAN RIBOSOMAL ELONGATION COMPLEX WITH AMINOACYL-TRNA, EEF1A, AND DIDEMNIN B
Descriptor:uL2, uL3, uL4, ...
Authors:Shao, S., Murray, J., Brown, A., Taunton, J., Ramakrishnan, V., Hegde, R.S.
Deposit date:2016-10-02
Release date:2016-11-30
Last modified:2018-10-17
Method:ELECTRON MICROSCOPY (3.31 Å)
Cite:Decoding Mammalian Ribosome-mRNA States by Translational GTPase Complexes.
Cell, 167, 2016
1N33
  • Download 1n33
  • View 1n33
Molmil generated image of 1n33
STRUCTURE OF THE THERMUS THERMOPHILUS 30S RIBOSOMAL SUBUNIT BOUND TO CODON AND NEAR-COGNATE TRANSFER RNA ANTICODON STEM-LOOP MISMATCHED AT THE SECOND CODON POSITION AT THE A SITE WITH PAROMOMYCIN
Descriptor:16S RIBOSOMAL RNA, ANTICODON STEM-LOOP OF SER TRANSFER RNA, A-SITE MESSENGER RNA FRAGMENT, ...
Authors:Ogle, J.M., Murphy IV, F.V., Tarry, M.J., Ramakrishnan, V.
Deposit date:2002-10-25
Release date:2002-11-29
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.35 Å)
Cite:Selection of tRNA by the Ribosome Requires a Transition from an Open to a Closed Form
Cell(Cambridge,Mass.), 111, 2002
5LZV
  • Download 5lzv
  • View 5lzv
Molmil generated image of 5lzv
STRUCTURE OF THE MAMMALIAN RIBOSOMAL TERMINATION COMPLEX WITH ACCOMMODATED ERF1(AAQ) AND ABCE1.
Descriptor:uL2, uL3, uL4, ...
Authors:Shao, S., Murray, J., Brown, A., Taunton, J., Ramakrishnan, V., Hegde, R.S.
Deposit date:2016-10-02
Release date:2016-11-30
Last modified:2018-10-03
Method:ELECTRON MICROSCOPY (3.35 Å)
Cite:Decoding Mammalian Ribosome-mRNA States by Translational GTPase Complexes.
Cell, 167, 2016
5MDY
  • Download 5mdy
  • View 5mdy
Molmil generated image of 5mdy
STRUCTURE OF ARFA AND TTRF2 BOUND TO THE 70S RIBOSOME (PRE-ACCOMMODATED STATE)
Descriptor:23S ribosomal RNA, 16S ribosomal RNA, 5S ribosomal RNA, ...
Authors:James, N.R., Brown, A., Gordiyenko, Y., Ramakrishnan, V.
Deposit date:2016-11-13
Release date:2016-12-21
Last modified:2018-10-17
Method:ELECTRON MICROSCOPY (3.35 Å)
Cite:Translational termination without a stop codon.
Science, 354, 2016
1HNW
  • Download 1hnw
  • View 1hnw
Molmil generated image of 1hnw
STRUCTURE OF THE THERMUS THERMOPHILUS 30S RIBOSOMAL SUBUNIT IN COMPLEX WITH TETRACYCLINE
Descriptor:16S RIBOSOMAL RNA, FRAGMENT OF MESSENGER RNA, 30S RIBOSOMAL PROTEIN S2, ...
Authors:Brodersen, D.E., Clemons Jr., W.M., Carter, A.P., Morgan-Warren, R., Wimberly, B.T., Ramakrishnan, V.
Deposit date:2000-12-08
Release date:2001-02-21
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:The structural basis for the action of the antibiotics tetracycline, pactamycin, and hygromycin B on the 30S ribosomal subunit.
Cell(Cambridge,Mass.), 103, 2000
1HNX
  • Download 1hnx
  • View 1hnx
Molmil generated image of 1hnx
STRUCTURE OF THE THERMUS THERMOPHILUS 30S RIBOSOMAL SUBUNIT IN COMPLEX WITH PACTAMYCIN
Descriptor:16S RIBOSOMAL RNA, FRAGMENT OF MESSENGER RNA, 30S RIBOSOMAL PROTEIN S2, ...
Authors:Brodersen, D.E., Clemons Jr., W.M., Carter, A.P., Morgan-Warren, R., Wimberly, B.T., Ramakrishnan, V.
Deposit date:2000-12-08
Release date:2001-02-21
Last modified:2013-05-22
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:The structural basis for the action of the antibiotics tetracycline, pactamycin, and hygromycin B on the 30S ribosomal subunit.
Cell(Cambridge,Mass.), 103, 2000
3J7Y
  • Download 3j7y
  • View 3j7y
Molmil generated image of 3j7y
STRUCTURE OF THE LARGE RIBOSOMAL SUBUNIT FROM HUMAN MITOCHONDRIA
Descriptor:16S rRNA, mt-tRNAVal, uL2, ...
Authors:Brown, A., Amunts, A., Bai, X.C., Sugimoto, Y., Edwards, P.C., Murshudov, G., Scheres, S.H.W., Ramakrishnan, V.
Deposit date:2014-08-26
Release date:2014-10-15
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Structure of the large ribosomal subunit from human mitochondria.
Science, 346, 2014
4K0K
  • Download 4k0k
  • View 4k0k
Molmil generated image of 4k0k
CRYSTAL STRUCTURE OF THE THERMUS THERMOPHILUS 30S RIBOSOMAL SUBUNIT COMPLEXED WITH A SERINE-ASL AND MRNA CONTAINING A STOP CODON
Descriptor:16S ribosomal RNA, 30S ribosomal protein S2, 30S ribosomal protein S3, ...
Authors:Fernandez, I.S., Ng, C.L., Kelley, A.C., Guowei, W., Yu, Y.T., Ramakrishnan, V.
Deposit date:2013-04-04
Release date:2013-06-26
Last modified:2013-08-21
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Unusual base pairing during the decoding of a stop codon by the ribosome.
Nature, 500, 2013
4WT8
  • Download 4wt8
  • View 4wt8
Molmil generated image of 4wt8
CRYSTAL STRUCTURE OF BACTOBOLIN A BOUND TO 70S RIBOSOME-TRNA COMPLEX
Descriptor:mRNA, 30S ribosomal protein S2, 30S ribosomal protein S3, ...
Authors:Amunts, A., Fiedorczuk, K., Ramakrishnan, V.
Deposit date:2014-10-29
Release date:2015-01-21
Last modified:2018-07-18
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Bactobolin A Binds to a Site on the 70S Ribosome Distinct from Previously Seen Antibiotics.
J.Mol.Biol., 427, 2015
3JAH
  • Download 3jah
  • View 3jah
Molmil generated image of 3jah
STRUCTURE OF A MAMMALIAN RIBOSOMAL TERMINATION COMPLEX WITH ABCE1, ERF1(AAQ), AND THE UAG STOP CODON
Descriptor:uL2, uL3, uL4, ...
Authors:Brown, A., Shao, S., Murray, J., Hegde, R.S., Ramakrishnan, V.
Deposit date:2015-06-10
Release date:2015-08-12
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (3.45 Å)
Cite:Structural basis for stop codon recognition in eukaryotes.
Nature, 524, 2015
4V5E
  • Download 4v5e
  • View 4v5e
Molmil generated image of 4v5e
INSIGHTS INTO TRANSLATIONAL TERMINATION FROM THE STRUCTURE OF RF2 BOUND TO THE RIBOSOME
Descriptor:16S ribosomal RNA, 30S RIBOSOMAL PROTEIN S2, 30S RIBOSOMAL PROTEIN S3, ...
Authors:Weixlbaumer, A., Jin, H., Neubauer, C., Voorhees, R.M., Petry, S., Kelley, A.C., Ramakrishnan, V.
Deposit date:2009-04-30
Release date:2014-07-09
Last modified:2018-03-14
Method:X-RAY DIFFRACTION (3.45 Å)
Cite:Insights Into Translational Termination from the Structure of Rf2 Bound to the Ribosome.
Science, 322, 2008
3JAM
  • Download 3jam
  • View 3jam
Molmil generated image of 3jam
CRYOEM STRUCTURE OF 40S-EIF1A-EIF1 COMPLEX FROM YEAST
Descriptor:18S rRNA, uS2, eS1, ...
Authors:Llacer, J.L., Hussain, T., Ramakrishnan, V.
Deposit date:2015-06-17
Release date:2015-08-12
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (3.46 Å)
Cite:Conformational Differences between Open and Closed States of the Eukaryotic Translation Initiation Complex.
Mol.Cell, 59, 2015
5LZZ
  • Download 5lzz
  • View 5lzz
Molmil generated image of 5lzz
STRUCTURE OF THE MAMMALIAN RESCUE COMPLEX WITH PELOTA AND HBS1L (COMBINED)
Descriptor:uL2, uL3, uL4, ...
Authors:Shao, S., Murray, J., Brown, A., Taunton, J., Ramakrishnan, V., Hegde, R.S.
Deposit date:2016-10-02
Release date:2016-11-30
Last modified:2018-10-17
Method:ELECTRON MICROSCOPY (3.47 Å)
Cite:Decoding Mammalian Ribosome-mRNA States by Translational GTPase Complexes.
Cell, 167, 2016
3J9M
  • Download 3j9m
  • View 3j9m
Molmil generated image of 3j9m
STRUCTURE OF THE HUMAN MITOCHONDRIAL RIBOSOME (CLASS 1)
Descriptor:16S rRNA, mt-tRNAVal, uL2m, ...
Authors:Amunts, A., Brown, A., Toots, J., Scheres, S.H., Ramakrishnan, V.
Deposit date:2015-02-08
Release date:2015-04-15
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Ribosome. The structure of the human mitochondrial ribosome.
Science, 348, 2015
4AQY
  • Download 4aqy
  • View 4aqy
Molmil generated image of 4aqy
STRUCTURE OF RIBOSOME-APRAMYCIN COMPLEXES
Descriptor:16S RIBOSOMAL RNA, 30S RIBOSOMAL PROTEIN S2, 30S RIBOSOMAL PROTEIN S3, ...
Authors:Matt, T., Ng, C.L., Lang, K., Sha, S.H., Akbergenov, R., Shcherbakov, D., Meyer, M., Duscha, S., Xie, J., Dubbaka, S.R., Perez-Fernandez, D., Vasella, A., Ramakrishnan, V., Schacht, J., Bottger, E.C.
Deposit date:2012-04-20
Release date:2012-07-18
Last modified:2019-03-06
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Dissociation of Antibacterial Activity and Aminoglycoside Ototoxicity in the 4-Monosubstituted 2-Deoxystreptamine Apramycin.
Proc.Natl.Acad.Sci.USA, 109, 2012
4V5A
  • Download 4v5a
  • View 4v5a
Molmil generated image of 4v5a
STRUCTURE OF THE RIBOSOME RECYCLING FACTOR BOUND TO THE THERMUS THERMOPHILUS 70S RIBOSOME WITH MRNA, ASL-PHE AND TRNA-FMET
Descriptor:16S ribosomal RNA, 30S RIBOSOMAL PROTEIN S2, 30S RIBOSOMAL PROTEIN S3, ...
Authors:Weixlbaumer, A., Petry, S., Dunham, C.M., Selmer, M., Kelley, A.C., Ramakrishnan, V.
Deposit date:2007-06-28
Release date:2014-07-09
Last modified:2018-03-07
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Crystal structure of the ribosome recycling factor bound to the ribosome.
Nat. Struct. Mol. Biol., 14, 2007
4V5D
  • Download 4v5d
  • View 4v5d
Molmil generated image of 4v5d
STRUCTURE OF THE THERMUS THERMOPHILUS 70S RIBOSOME IN COMPLEX WITH MRNA, PAROMOMYCIN, ACYLATED A- AND P-SITE TRNAS, AND E-SITE TRNA.
Descriptor:16S ribosomal RNA, 30S RIBOSOMAL PROTEIN S2, 30S RIBOSOMAL PROTEIN S3, ...
Authors:Voorhees, R.M., Weixlbaumer, A., Loakes, D., Kelley, A.C., Ramakrishnan, V.
Deposit date:2009-03-24
Release date:2014-07-09
Last modified:2018-03-07
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Insights into substrate stabilization from snapshots of the peptidyl transferase center of the intact 70S ribosome.
Nat. Struct. Mol. Biol., 16, 2009
5LZW
  • Download 5lzw
  • View 5lzw
Molmil generated image of 5lzw
STRUCTURE OF THE MAMMALIAN RESCUE COMPLEX WITH PELOTA AND HBS1L ASSEMBLED ON A TRUNCATED MRNA.
Descriptor:uL2, uL3, uL4, ...
Authors:Shao, S., Murray, J., Brown, A., Taunton, J., Ramakrishnan, V., Hegde, R.S.
Deposit date:2016-10-02
Release date:2016-11-30
Last modified:2018-10-03
Method:ELECTRON MICROSCOPY (3.53 Å)
Cite:Decoding Mammalian Ribosome-mRNA States by Translational GTPase Complexes.
Cell, 167, 2016
5LMN
  • Download 5lmn
  • View 5lmn
Molmil generated image of 5lmn
STRUCTURE OF BACTERIAL 30S-IF1-IF3-MRNA TRANSLATION PRE-INITIATION COMPLEX (STATE-1A)
Descriptor:16S ribosomal RNA, 30S ribosomal protein S2, 30S ribosomal protein S3, ...
Authors:Hussain, T., Llacer, J.L., Wimberly, B.T., Ramakrishnan, V.
Deposit date:2016-08-01
Release date:2016-10-05
Last modified:2018-11-21
Method:ELECTRON MICROSCOPY (3.55 Å)
Cite:Large-Scale Movements of IF3 and tRNA during Bacterial Translation Initiation.
Cell, 167, 2016
4V5F
  • Download 4v5f
  • View 4v5f
Molmil generated image of 4v5f
THE STRUCTURE OF THE RIBOSOME WITH ELONGATION FACTOR G TRAPPED IN THE POST-TRANSLOCATIONAL STATE
Descriptor:16S ribosomal RNA, 30S RIBOSOMAL PROTEIN S2, 30S RIBOSOMAL PROTEIN S3, ...
Authors:Gao, Y.-G., Selmer, M., Dunham, C.M., Weixlbaumer, A., Kelley, A.C., Ramakrishnan, V.
Deposit date:2009-09-01
Release date:2014-07-09
Last modified:2018-03-14
Method:X-RAY DIFFRACTION (3.6 Å)
Cite:The structure of the ribosome with elongation factor G trapped in the posttranslocational state.
Science, 326, 2009
4V5G
  • Download 4v5g
  • View 4v5g
Molmil generated image of 4v5g
THE CRYSTAL STRUCTURE OF THE 70S RIBOSOME BOUND TO EF-TU AND TRNA
Descriptor:16S RIBOSOMAL RNA, 30S RIBOSOMAL PROTEIN S2, 30S RIBOSOMAL PROTEIN S3, ...
Authors:Schmeing, T.M., Voorhees, R.M., Ramakrishnan, V.
Deposit date:2009-09-01
Release date:2014-07-09
Last modified:2018-04-18
Method:X-RAY DIFFRACTION (3.6 Å)
Cite:The crystal structure of the ribosome bound to EF-Tu and aminoacyl-tRNA.
Science, 326, 2009
4V7K
  • Download 4v7k
  • View 4v7k
Molmil generated image of 4v7k
STRUCTURE OF RELE NUCLEASE BOUND TO THE 70S RIBOSOME (POSTCLEAVAGE STATE)
Descriptor:30S ribosomal protein S2, 30S ribosomal protein S3, 30S ribosomal protein S4, ...
Authors:Neubauer, C., Gao, Y.-G., Andersen, K.R., Dunham, C.M., Kelley, A.C., Hentschel, J., Gerdes, K., Ramakrishnan, V., Brodersen, D.E.
Deposit date:2009-11-02
Release date:2014-07-09
Last modified:2014-12-10
Method:X-RAY DIFFRACTION (3.6 Å)
Cite:The structural basis for mRNA recognition and cleavage by the ribosome-dependent endonuclease RelE.
Cell(Cambridge,Mass.), 139, 2009
5IT7
  • Download 5it7
  • View 5it7
Molmil generated image of 5it7
STRUCTURE OF THE KLUYVEROMYCES LACTIS 80S RIBOSOME IN COMPLEX WITH THE CRICKET PARALYSIS VIRUS IRES AND EEF2
Descriptor:25S ribosomal RNA, 5S ribosomal RNA, 5.8S ribosomal RNA, ...
Authors:Murray, J., Savva, C.G., Shin, B.S., Dever, T.E., Ramakrishnan, V., Fernandez, I.S.
Deposit date:2016-03-16
Release date:2016-05-18
Last modified:2018-11-21
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Structural characterization of ribosome recruitment and translocation by type IV IRES.
Elife, 5, 2016
1N36
  • Download 1n36
  • View 1n36
Molmil generated image of 1n36
STRUCTURE OF THE THERMUS THERMOPHILUS 30S RIBOSOMAL SUBUNIT IN THE PRESENCE OF CRYSTALLOGRAPHICALLY DISORDERED CODON AND NEAR-COGNATE TRANSFER RNA ANTICODON STEM-LOOP MISMATCHED AT THE SECOND CODON POSITION
Descriptor:16S RIBOSOMAL RNA, 30S RIBOSOMAL PROTEIN S2, 30S RIBOSOMAL PROTEIN S3, ...
Authors:Ogle, J.M., Murphy IV, F.V., Tarry, M.J., Ramakrishnan, V.
Deposit date:2002-10-25
Release date:2002-11-29
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.65 Å)
Cite:Selection of tRNA by the Ribosome Requires a Transition from an Open to a Closed Form
Cell(Cambridge,Mass.), 111, 2002