6YSF
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6YSL
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7B2A
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7B29
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7B2D
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7B26
| CirpA1 in complex with pseudo-monomeric Properdin lacking TSR2-3 | Descriptor: | CirpA1, Properdin, alpha-D-mannopyranose, ... | Authors: | Lea, S.M, Johnson, S, Braunger, K. | Deposit date: | 2020-11-26 | Release date: | 2021-12-08 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (3.4 Å) | Cite: | Structure and function of a family of tick-derived complement inhibitors targeting properdin. Nat Commun, 13, 2022
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7B28
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6SD6
| Structure of VapBC from Shigella sonnei | Descriptor: | Antitoxin, tRNA(fMet)-specific endonuclease VapC | Authors: | Lea, S.M, Hollingshead, S. | Deposit date: | 2019-07-26 | Release date: | 2020-08-26 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.61 Å) | Cite: | Polymorphisms in the VapBC toxin:antitoxin system mediate high frequency plasmid loss in Shigella sonnei To Be Published
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8FY3
| Structure of NOT1:NOT10:NOT11 module of the human CCR4-NOT complex | Descriptor: | CCR4-NOT transcription complex subunit 1, CCR4-NOT transcription complex subunit 10, CCR4-NOT transcription complex subunit 11 | Authors: | Lea, S.M, Deme, J.C, Raisch, T, Pekovic, F, Valkov, E. | Deposit date: | 2023-01-25 | Release date: | 2023-07-26 | Last modified: | 2023-08-02 | Method: | ELECTRON MICROSCOPY (2.88 Å) | Cite: | Structure and assembly of the NOT10:11 module of the CCR4-NOT complex. Commun Biol, 6, 2023
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8FY4
| Structure of NOT1:NOT10:NOT11 module of the chicken CCR4-NOT complex | Descriptor: | CCR4-NOT transcription complex subunit 1, CCR4-NOT transcription complex subunit 10, CCR4-NOT transcription complex subunit 11 | Authors: | Lea, S.M, Deme, J.C, Raisch, T, Levdansky, Y, Valkov, E. | Deposit date: | 2023-01-25 | Release date: | 2023-08-30 | Method: | ELECTRON MICROSCOPY (2.57 Å) | Cite: | Structure and assembly of the NOT10:11 module of the CCR4-NOT complex. Commun Biol, 6, 2023
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1H2Q
| Human CD55 domains 3 & 4 | Descriptor: | COMPLEMENT DECAY-ACCELERATING FACTOR | Authors: | Williams, P, Chaudhry, Y, Goodfellow, I.G, Billington, J, Powell, R, Spiller, O.B, Evans, D.J, Lea, S.M. | Deposit date: | 2002-08-13 | Release date: | 2003-09-25 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Mapping Cd55 Function. The Structure of Two Pathogen-Binding Domains at 1.7 A J.Biol.Chem., 278, 2003
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1H03
| Human CD55 domains 3 & 4 | Descriptor: | COMPLEMENT DECAY-ACCELERATING FACTOR | Authors: | Williams, P, Chaudhry, Y, Goodfellow, I, Billington, J, Spiller, B, Evans, D.J, Lea, S.M. | Deposit date: | 2002-06-11 | Release date: | 2003-03-20 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Mapping Cd55 Function. The Structure of Two Pathogen-Binding Domains at 1.7 A J.Biol.Chem., 278, 2003
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1H04
| Human CD55 domains 3 & 4 | Descriptor: | COMPLEMENT DECAY-ACCELERATING FACTOR, NICKEL (II) ION | Authors: | Williams, P, Chaudhry, Y, Goodfellow, I, Billington, J, Spiller, B, Evans, D.J, Lea, S.M. | Deposit date: | 2002-06-11 | Release date: | 2003-03-20 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Mapping Cd55 Function. The Structure of Two Pathogen-Binding Domains at 1.7 A J.Biol.Chem., 278, 2003
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1H2P
| Human CD55 domains 3 & 4 | Descriptor: | COMPLEMENT DECAY-ACCELERATING FACTOR | Authors: | Williams, P, Chaudhry, Y, Goodfellow, I, Billington, J, Spiller, B, Evans, D.J, Lea, S.M. | Deposit date: | 2002-08-13 | Release date: | 2003-03-20 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Mapping Cd55 Function. The Structure of Two Pathogen-Binding Domains at 1.7 A J.Biol.Chem., 278, 2003
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7YXX
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7YXY
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5NQX
| Structure of a fHbp(V1.1):PorA(P1.16) chimera. Fusion at fHbp position 294. | Descriptor: | Factor H binding protein,Major outer membrane protein P.IA,Factor H binding protein | Authors: | Johnson, S, Jongerius, I, Lea, S.M, Tang, C.M. | Deposit date: | 2017-04-21 | Release date: | 2018-02-28 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (3.66 Å) | Cite: | Structure-based design of chimeric antigens for multivalent protein vaccines. Nat Commun, 9, 2018
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5NQP
| Structure of a fHbp(V1.4):PorA(P1.16) chimera. Fusion at fHbp position 151. | Descriptor: | 1,2-ETHANEDIOL, CHLORIDE ION, Factor H binding protein variant B16_001,Major outer membrane protein P.IA,Factor H binding protein variant B16_001, ... | Authors: | Johnson, S, Hollingshead, S, Lea, S.M, Tang, C.M. | Deposit date: | 2017-04-20 | Release date: | 2018-02-28 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.86 Å) | Cite: | Structure-based design of chimeric antigens for multivalent protein vaccines. Nat Commun, 9, 2018
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1H8T
| Echovirus 11 | Descriptor: | 12-AMINO-DODECANOIC ACID, ECHOVIRUS 11 COAT PROTEIN VP1, ECHOVIRUS 11 COAT PROTEIN VP2, ... | Authors: | Stuart, A, McKee, T, Williams, P.A, Harley, C, Stuart, D.I, Brown, T.D.K, Lea, S.M. | Deposit date: | 2001-02-15 | Release date: | 2002-07-11 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Determination of the Structure of a Decay Accelerating Factor-Binding Clinical Isolate of Echovirus 11 Allows Mapping of Mutants with Altered Receptor Requirements for Infection J.Virol., 76, 2002
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8SA4
| Adenosylcobalamin-bound riboswitch dimer, form 3 | Descriptor: | Adenosylcobalamin, adenosylcobalamin riboswitch form 3 | Authors: | Ding, J, Deme, J.C, Stagno, J.R, Yu, P, Lea, S.M, Wang, Y.X. | Deposit date: | 2023-03-31 | Release date: | 2023-07-26 | Last modified: | 2023-10-25 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Capturing heterogeneous conformers of cobalamin riboswitch by cryo-EM. Nucleic Acids Res., 51, 2023
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8SA5
| Adenosylcobalamin-bound riboswitch dimer, form 4 | Descriptor: | Adenosylcobalamin, adenosylcobalamin riboswitch form 4 | Authors: | Ding, J, Deme, J.C, Stagno, J.R, Yu, P, Lea, S.M, Wang, Y.X. | Deposit date: | 2023-03-31 | Release date: | 2023-07-26 | Last modified: | 2023-10-25 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Capturing heterogeneous conformers of cobalamin riboswitch by cryo-EM. Nucleic Acids Res., 51, 2023
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8SA3
| Adenosylcobalamin-bound riboswitch dimer, form 2 | Descriptor: | Adenosylcobalamin, adenosylcobalamin riboswitch form 2 | Authors: | Ding, J, Deme, J.C, Stagno, J.R, Yu, P, Lea, S.M, Wang, Y.X. | Deposit date: | 2023-03-31 | Release date: | 2023-07-26 | Last modified: | 2023-10-25 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | Capturing heterogeneous conformers of cobalamin riboswitch by cryo-EM. Nucleic Acids Res., 51, 2023
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8SA6
| apo form of adenosylcobalamin riboswitch dimer | Descriptor: | apo form of adenosylcobalamin riboswitch dimer | Authors: | Ding, J, Deme, J.C, Stagno, J.R, Yu, P, Lea, S.M, Wang, Y.X. | Deposit date: | 2023-03-31 | Release date: | 2023-07-26 | Last modified: | 2023-10-25 | Method: | ELECTRON MICROSCOPY (5.3 Å) | Cite: | Capturing heterogeneous conformers of cobalamin riboswitch by cryo-EM. Nucleic Acids Res., 51, 2023
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8SA2
| Adenosylcobalamin-bound riboswitch dimer, form 1 | Descriptor: | Adenosylcobalamin, adenosylcobalamin riboswitch form 1 | Authors: | Ding, J, Deme, J.C, Stagno, J.R, Yu, P, Lea, S.M, Wang, Y.X. | Deposit date: | 2023-03-31 | Release date: | 2023-07-26 | Last modified: | 2023-10-25 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Capturing heterogeneous conformers of cobalamin riboswitch by cryo-EM. Nucleic Acids Res., 51, 2023
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8UCS
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