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2TPR
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BU of 2tpr by Molmil
X-RAY STRUCTURE OF TRYPANOTHIONE REDUCTASE FROM CRITHIDIA FASCICULATA AT 2.4 ANGSTROMS RESOLUTION
Descriptor: FLAVIN-ADENINE DINUCLEOTIDE, TRYPANOTHIONE REDUCTASE
Authors:Kuriyan, J, Kong, X.-P, Krishna, T.S.R.
Deposit date:1991-08-22
Release date:1993-10-31
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:X-ray structure of trypanothione reductase from Crithidia fasciculata at 2.4-A resolution.
Proc.Natl.Acad.Sci.USA, 88, 1991
1TRB
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BU of 1trb by Molmil
CONVERGENT EVOLUTION OF SIMILAR FUNCTION IN TWO STRUCTURALLY DIVERGENT ENZYMES
Descriptor: FLAVIN-ADENINE DINUCLEOTIDE, THIOREDOXIN REDUCTASE
Authors:Kuriyan, J, Krishna, T.S.R.
Deposit date:1991-09-07
Release date:1994-01-31
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2 Å)
Cite:Convergent evolution of similar function in two structurally divergent enzymes.
Nature, 352, 1991
1MBC
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BU of 1mbc by Molmil
X-RAY STRUCTURE AND REFINEMENT OF CARBON-MONOXY (FE II)-MYOGLOBIN AT 1.5 ANGSTROMS RESOLUTION
Descriptor: CARBON MONOXIDE, MYOGLOBIN, PROTOPORPHYRIN IX CONTAINING FE, ...
Authors:Kuriyan, J, Petsko, G.A.
Deposit date:1988-09-15
Release date:1989-01-09
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:X-ray structure and refinement of carbon-monoxy (Fe II)-myoglobin at 1.5 A resolution.
J.Mol.Biol., 192, 1986
1A06
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BU of 1a06 by Molmil
CALMODULIN-DEPENDENT PROTEIN KINASE FROM RAT
Descriptor: CALCIUM/CALMODULIN-DEPENDENT PROTEIN KINASE
Authors:Kuriyan, J, Goldberg, J.
Deposit date:1997-12-09
Release date:1998-04-08
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural basis for the autoinhibition of calcium/calmodulin-dependent protein kinase I.
Cell(Cambridge,Mass.), 84, 1996
1BF5
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BU of 1bf5 by Molmil
TYROSINE PHOSPHORYLATED STAT-1/DNA COMPLEX
Descriptor: DNA (5'-D(*AP*CP*AP*GP*TP*TP*TP*CP*CP*CP*GP*TP*AP*AP*AP*TP*G P*C)-3'), DNA (5'-D(*TP*GP*CP*AP*TP*TP*TP*AP*CP*GP*GP*GP*AP*AP*AP*CP*T P*G)-3'), SIGNAL TRANSDUCER AND ACTIVATOR OF TRANSCRIPTION 1-ALPHA/BETA
Authors:Kuriyan, J, Zhao, Y, Chen, X, Vinkemeier, U, Jeruzalmi, D, Darnell Jr, J.E.
Deposit date:1998-05-27
Release date:1998-08-12
Last modified:2022-12-21
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Crystal structure of a tyrosine phosphorylated STAT-1 dimer bound to DNA.
Cell(Cambridge,Mass.), 93, 1998
2MA2
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BU of 2ma2 by Molmil
Solution structure of RasGRP2 EF hands bound to calcium
Descriptor: RAS guanyl-releasing protein 2
Authors:Kuriyan, J, Iwig, J, Vercoulen, Y, Das, R, Barros, T, Limnander, A, Che, Y, Pelton, J, Wemmer, D, Roose, J.
Deposit date:2013-06-24
Release date:2013-08-21
Method:SOLUTION NMR
Cite:Structural analysis of autoinhibition in the Ras-specific exchange factor RasGRP1.
Elife, 2, 2013
3KK9
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BU of 3kk9 by Molmil
CaMKII Substrate Complex B
Descriptor: Calcium/calmodulin dependent protein kinase II
Authors:Kuriyan, J, Chao, L.H, Pellicena, P, Deindl, S, Barclay, L.A, Schulman, H.
Deposit date:2009-11-04
Release date:2010-02-09
Last modified:2021-10-13
Method:X-RAY DIFFRACTION (3.206 Å)
Cite:Intersubunit capture of regulatory segments is a component of cooperative CaMKII activation.
Nat.Struct.Mol.Biol., 17, 2010
3KK8
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BU of 3kk8 by Molmil
CaMKII Substrate Complex A
Descriptor: Calcium/calmodulin dependent protein kinase II, MAGNESIUM ION
Authors:Kuriyan, J, Chao, L.H, Pellicena, P, Deindl, S, Barclay, L.A, Schulman, H.
Deposit date:2009-11-04
Release date:2010-02-09
Last modified:2021-10-13
Method:X-RAY DIFFRACTION (1.72 Å)
Cite:Intersubunit capture of regulatory segments is a component of cooperative CaMKII activation.
Nat.Struct.Mol.Biol., 17, 2010
3KL8
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BU of 3kl8 by Molmil
CaMKIINtide Inhibitor Complex
Descriptor: Calcium/calmodulin dependent protein kinase II, Calcium/calmodulin-dependent protein kinase II inhibitor 1
Authors:Kuriyan, J, Chao, L.H, Pellicena, P, Deindl, S, Barclay, L.A, Schulman, H.
Deposit date:2009-11-06
Release date:2010-02-09
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (3.372 Å)
Cite:Intersubunit capture of regulatory segments is a component of cooperative CaMKII activation.
Nat.Struct.Mol.Biol., 17, 2010
8E4T
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BU of 8e4t by Molmil
Crystal structure of the kinase domain of RTKC8 from the choanoflagellate Monosiga brevicollis
Descriptor: PHOSPHATE ION, RTKC8 Kinase domain, STAUROSPORINE
Authors:Bajaj, T, Gee, C.L, Kuriyan, J.
Deposit date:2022-08-18
Release date:2023-06-21
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Crystal structure of the kinase domain of a receptor tyrosine kinase from a choanoflagellate, Monosiga brevicollis.
Plos One, 18, 2023
1AYC
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BU of 1ayc by Molmil
CRYSTAL STRUCTURES OF PEPTIDE COMPLEXES OF THE AMINO-TERMINAL SH2 DOMAIN OF THE SYP TYROSINE PHOSPHATASE
Descriptor: PEPTIDE PDGFR-740, PROTEIN-TYROSINE PHOSPHATASE SYP (N-TERMINAL SH2 DOMAIN)
Authors:Lee, C.-H, Kuriyan, J.
Deposit date:1994-05-15
Release date:1994-08-31
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structures of peptide complexes of the amino-terminal SH2 domain of the Syp tyrosine phosphatase.
Structure, 2, 1994
1AYA
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BU of 1aya by Molmil
CRYSTAL STRUCTURES OF PEPTIDE COMPLEXES OF THE AMINO-TERMINAL SH2 DOMAIN OF THE SYP TYROSINE PHOSPHATASE
Descriptor: PEPTIDE PDGFR-1009, PROTEIN-TYROSINE PHOSPHATASE SYP (N-TERMINAL SH2 DOMAIN)
Authors:Lee, C.-H, Kuriyan, J.
Deposit date:1994-05-15
Release date:1994-08-31
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Crystal structures of peptide complexes of the amino-terminal SH2 domain of the Syp tyrosine phosphatase.
Structure, 2, 1994
1AYB
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BU of 1ayb by Molmil
CRYSTAL STRUCTURES OF PEPTIDE COMPLEXES OF THE AMINO-TERMINAL SH2 DOMAIN OF THE SYP TYROSINE PHOSPHATASE
Descriptor: PEPTIDE IRS-1-895, PROTEIN-TYROSINE PHOSPHATASE SYP (N-TERMINAL SH2 DOMAIN)
Authors:Lee, C.-H, Kuriyan, J.
Deposit date:1994-05-15
Release date:1994-08-31
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:Crystal structures of peptide complexes of the amino-terminal SH2 domain of the Syp tyrosine phosphatase.
Structure, 2, 1994
1AYD
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BU of 1ayd by Molmil
CRYSTAL STRUCTURES OF PEPTIDE COMPLEXES OF THE AMINO-TERMINAL SH2 DOMAIN OF THE SYP TYROSINE PHOSPHATASE
Descriptor: PROTEIN-TYROSINE PHOSPHATASE SYP (N-TERMINAL SH2 DOMAIN)
Authors:Lee, C.-H, Kuriyan, J.
Deposit date:1994-05-15
Release date:1994-08-31
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structures of peptide complexes of the amino-terminal SH2 domain of the Syp tyrosine phosphatase.
Structure, 2, 1994
6UAN
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BU of 6uan by Molmil
B-Raf:14-3-3 complex
Descriptor: 14-3-3 zeta, Serine/threonine-protein kinase B-raf
Authors:Kondo, Y, Ognjenovic, J, Banerjee, S, Karandur, D, Merk, A, Kulhanek, K, Wong, K, Roose, J.P, Subramaniam, S, Kuriyan, J.
Deposit date:2019-09-11
Release date:2019-09-25
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Cryo-EM structure of a dimeric B-Raf:14-3-3 complex reveals asymmetry in the active sites of B-Raf kinases.
Science, 366, 2019
8UNF
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BU of 8unf by Molmil
Cryo-EM structure of T4 Bacteriophage Clamp Loader with Sliding Clamp and DNA
Descriptor: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Sliding clamp, ...
Authors:Huang, Y, Marcus, K, Subramanian, S, Gee, L.C, Gorday, K, Ghaffari-Kashani, S, Luo, X, Zhang, L, O'Donnell, M, Subramanian, S, Kuriyan, J.
Deposit date:2023-10-18
Release date:2023-12-13
Last modified:2024-01-17
Method:ELECTRON MICROSCOPY (3.15 Å)
Cite:Autoinhibition of a clamp-loader ATPase revealed by deep mutagenesis and cryo-EM.
Nat.Struct.Mol.Biol., 2024
8UNH
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BU of 8unh by Molmil
Cryo-EM structure of T4 Bacteriophage Clamp Loader with Sliding Clamp
Descriptor: MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, Sliding clamp, ...
Authors:Huang, Y, Marcus, K, Subramanian, S, Gee, L.C, Gorday, K, Ghaffari-Kashani, S, Luo, X, Zhang, L, O'Donnell, M, Subramanian, S, Kuriyan, J.
Deposit date:2023-10-19
Release date:2023-12-13
Last modified:2024-01-17
Method:ELECTRON MICROSCOPY (3.21 Å)
Cite:Autoinhibition of a clamp-loader ATPase revealed by deep mutagenesis and cryo-EM.
Nat.Struct.Mol.Biol., 2024
6OF9
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BU of 6of9 by Molmil
Structure of the Chlamydamonas reinhardtii CamKII hub homology domain
Descriptor: CaMKII hub
Authors:McSpadden, E.D, Chi, C.C, Gee, C.L, Kuriyan, J.
Deposit date:2019-03-28
Release date:2019-04-17
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (3 Å)
Cite:Variation in assembly stoichiometry in non-metazoan homologs of the hub domain of Ca2+/calmodulin-dependent protein kinase II.
Protein Sci., 28, 2019
5WDO
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BU of 5wdo by Molmil
H-Ras bound to GMP-PNP at 277K
Descriptor: CALCIUM ION, GTPase HRas, MAGNESIUM ION, ...
Authors:Cofsky, J.C, Bandaru, P, Gee, C.L, Kuriyan, J.
Deposit date:2017-07-05
Release date:2017-07-19
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Deconstruction of the Ras switching cycle through saturation mutagenesis.
Elife, 6, 2017
7SZ7
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BU of 7sz7 by Molmil
Cryo-EM structure of the extracellular module of the full-length EGFR bound to TGF-alpha. "tips-juxtaposed" conformation
Descriptor: Epidermal growth factor receptor, Transforming growth factor alpha
Authors:Huang, Y, Ognjenovic, J, Karandur, D, Miller, K, Merk, A, Subramaniam, S, Kuriyan, J.
Deposit date:2021-11-25
Release date:2021-12-15
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:A molecular mechanism for the generation of ligand-dependent differential outputs by the epidermal growth factor receptor.
Elife, 10, 2021
7SYE
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BU of 7sye by Molmil
Cryo-EM structure of the extracellular module of the full-length EGFR bound to EGF. "tips-separated" conformation
Descriptor: Epidermal growth factor, Epidermal growth factor receptor
Authors:Huang, Y, Ognjenovic, J, Karandur, D, Miller, K, Merk, A, Subramaniam, S, Kuriyan, J.
Deposit date:2021-11-24
Release date:2021-12-22
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:A molecular mechanism for the generation of ligand-dependent differential outputs by the epidermal growth factor receptor.
Elife, 10, 2021
7SZ0
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BU of 7sz0 by Molmil
Cryo-EM structure of the extracellular module of the full-length EGFR L834R bound to EGF. "tips-juxtaposed" conformation
Descriptor: Epidermal growth factor, Epidermal growth factor receptor
Authors:Huang, Y, Ognjenovic, J, Karandur, D, Miller, K, Merk, A, Subramaniam, S, Kuriyan, J.
Deposit date:2021-11-25
Release date:2021-12-22
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:A molecular mechanism for the generation of ligand-dependent differential outputs by the epidermal growth factor receptor.
Elife, 10, 2021
7SZ5
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BU of 7sz5 by Molmil
Cryo-EM structure of the extracellular module of the full-length EGFR bound to TGF-alpha "tips-separated" conformation
Descriptor: Epidermal growth factor receptor, Transforming growth factor alpha
Authors:Huang, Y, Ognjenovic, J, Karandur, D, Miller, K, Merk, A, Subramaniam, S, Kuriyan, J.
Deposit date:2021-11-25
Release date:2021-12-22
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:A molecular mechanism for the generation of ligand-dependent differential outputs by the epidermal growth factor receptor.
Elife, 10, 2021
7SZ1
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BU of 7sz1 by Molmil
Cryo-EM structure of the extracellular module of the full-length EGFR L834R bound to EGF. "tips-separated" conformation
Descriptor: Epidermal growth factor, Epidermal growth factor receptor
Authors:Huang, Y, Ognjenovic, J, Karandur, D, Miller, K, Merk, A, Subramaniam, S, Kuriyan, J.
Deposit date:2021-11-25
Release date:2021-12-22
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:A molecular mechanism for the generation of ligand-dependent differential outputs by the epidermal growth factor receptor.
Elife, 10, 2021
7SYD
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BU of 7syd by Molmil
Cryo-EM structure of the extracellular module of the full-length EGFR bound to EGF "tips-juxtaposed" conformation
Descriptor: Epidermal growth factor, Epidermal growth factor receptor
Authors:Huang, Y, Ognjenovic, J, Karandur, D, Miller, K, Merk, A, Subramaniam, S, Kuriyan, J.
Deposit date:2021-11-24
Release date:2021-12-22
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:A molecular mechanism for the generation of ligand-dependent differential outputs by the epidermal growth factor receptor.
Elife, 10, 2021

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