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1SH9
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COMPARING THE ACCUMULATION OF ACTIVE SITE AND NON-ACTIVE SITE MUTATIONS IN THE HIV-1 PROTEASE
分子名称:POL polyprotein, RITONAVIR
著者Clemente, J.C., Moose, R.E., Hemrajani, R., Govindasamy, L., Reutzel, R., McKenna, R., Abanje-McKenna, M., Goodenow, M.M., Dunn, B.M.
登録日2004-02-25
公開日2004-10-05
最終更新日2017-10-11
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Comparing the Accumulation of Active- and Nonactive-Site Mutations in the HIV-1 Protease.
Biochemistry, 43, 2004
2ILI
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REFINE ATOMIC STRUCTURE OF HUMAN CARBONIC ANHYDRASE II
分子名称:Carbonic anhydrase 2, ZINC ION
著者Fisher, S.Z.
登録日2006-10-02
公開日2007-06-05
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.05 Å)
主引用文献Atomic crystal and molecular dynamics simulation structures of human carbonic anhydrase II: insights into the proton transfer mechanism
Biochemistry, 46, 2007
3IXO
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CRYSTAL STRUCTURE OF UNCOMPLEXED HIV_1 PROTEASE SUBTYPE A
分子名称:HIV-1 protease
著者Robbins, A., McKenna, R.
登録日2009-09-04
公開日2010-03-02
最終更新日2012-03-28
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structure of the unbound form of HIV-1 subtype A protease: comparison with unbound forms of proteases from other HIV subtypes.
Acta Crystallogr.,Sect.D, 66, 2010
3V3F
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KINETIC AND STRUCTURAL STUDIES OF THERMOSTABILIZED MUTANTS OF HCA II.
分子名称:Carbonic anhydrase 2, ZINC ION, CHLORIDE ION
著者Boone, C.D., Fisher, S.Z., McKenna, R.
登録日2011-12-13
公開日2012-06-20
最終更新日2017-11-08
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Kinetic and structural characterization of thermostabilized mutants of human carbonic anhydrase II.
Protein Eng.Des.Sel., 25, 2012
3V3G
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KINETIC AND STRUCTURAL STUDIES OF THERMOSTABILIZED MUTANTS OF HCA II.
分子名称:Carbonic anhydrase 2, ZINC ION, CHLORIDE ION
著者Boone, C.D., Fisher, S.Z., McKenna, R.
登録日2011-12-13
公開日2012-06-20
最終更新日2017-11-08
実験手法X-RAY DIFFRACTION (1.5581 Å)
主引用文献Kinetic and structural characterization of thermostabilized mutants of human carbonic anhydrase II.
Protein Eng.Des.Sel., 25, 2012
3V3H
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KINETIC AND STRUCTURAL STUDIES OF THERMOSTABILIZED MUTANTS OF HCA II.
分子名称:Carbonic anhydrase 2, ZINC ION, CHLORIDE ION
著者Boone, C.D., Fisher, S.Z., McKenna, R.
登録日2011-12-13
公開日2012-06-20
最終更新日2017-11-08
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Kinetic and structural characterization of thermostabilized mutants of human carbonic anhydrase II.
Protein Eng.Des.Sel., 25, 2012
3V3I
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KINETIC AND STRUCTURAL STUDIES OF THERMOSTABILIZED MUTANTS OF HCA II.
分子名称:Carbonic anhydrase 2, ZINC ION, CHLORIDE ION
著者Boone, C.D., Fisher, S.Z., McKenna, R.
登録日2011-12-13
公開日2012-06-20
最終更新日2017-11-08
実験手法X-RAY DIFFRACTION (1.73 Å)
主引用文献Kinetic and structural characterization of thermostabilized mutants of human carbonic anhydrase II.
Protein Eng.Des.Sel., 25, 2012
3V3J
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KINETIC AND STRUCTURAL STUDIES OF THERMOSTABILIZED MUTANTS OF HCA II.
分子名称:Carbonic anhydrase 2, ZINC ION
著者Boone, C.D., Fisher, S.Z., McKenna, R.
登録日2011-12-13
公開日2012-06-20
最終更新日2017-11-08
実験手法X-RAY DIFFRACTION (1.63 Å)
主引用文献Kinetic and structural characterization of thermostabilized mutants of human carbonic anhydrase II.
Protein Eng.Des.Sel., 25, 2012
1KVP
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STRUCTURAL ANALYSIS OF THE SPIROPLASMA VIRUS, SPV4, IMPLICATIONS FOR EVOLUTIONARY VARIATION TO OBTAIN HOST DIVERSITY AMONG THE MICROVIRIDAE, ELECTRON MICROSCOPY, ALPHA CARBONS ONLY
分子名称:SPV4 CAPSID PROTEIN VP1
著者McKenna, R.
登録日1997-12-12
公開日1999-02-23
最終更新日2011-07-13
実験手法ELECTRON MICROSCOPY (27 Å)
主引用文献Structural analysis of the Spiroplasma virus, SpV4: implications for evolutionary variation to obtain host diversity among the Microviridae.
Structure, 6, 1998
1IJJ
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THE X-RAY CRYSTAL STRUCTURE OF THE COMPLEX BETWEEN RABBIT SKELETAL MUSCLE ACTIN AND LATRUNCULIN A AT 2.85 A RESOLUTION
分子名称:ACTIN, ALPHA SKELETAL MUSCLE, MAGNESIUM ION, ...
著者Vorobiev, S.M., Bubb, M.R., Almo, S.C.
登録日2001-04-26
公開日2002-04-15
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.85 Å)
主引用文献Polylysine induces an antiparallel actin dimer that nucleates filament assembly: crystal structure at 3.5-A resolution
J.Biol.Chem., 277, 2002
2FLE
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STRUCTURAL ANALYSIS OF ASYMMETRIC INHIBITOR BOUND TO THE HIV-1 PROTEASE V82A MUTANT
分子名称:pol protein, GLYCEROL, (2S,2'S)-N,N'-[(2S,3S,4S,5S)-1-CYCLOHEXYL-3,4-DIHYDROXY-6-PHENYLHEXANE-2,5-DIYL]BIS[3-METHYL-2-({[METHYL(PYRIDIN-2-YLMETHYL)AMINO]CARBONYL}AMINO)BUTANAMIDE]
著者Clemente, J.C., Robbins, A., Dunn, B.M., Sussman, F.
登録日2006-01-05
公開日2007-01-16
最終更新日2017-10-18
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Design, synthesis, evaluation, and crystallographic-based structural studies of HIV-1 protease inhibitors with reduced response to the V82A mutation.
J.Med.Chem., 51, 2008
2NWO
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STRUCTURAL AND KINETIC EFFECT OF HYDROPHOBIC MUTATIONS IN THE ACTIVE SITE OF HUMAN CARBONIC ANHYDRASE II
分子名称:Carbonic anhydrase 2, ZINC ION
著者Fisher, S.Z., McKenna, R.
登録日2006-11-16
公開日2007-04-24
最終更新日2018-01-24
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Speeding Up Proton Transfer in a Fast Enzyme: Kinetic and Crystallographic Studies on the Effect of Hydrophobic Amino Acid Substitutions in the Active Site of Human Carbonic Anhydrase II.
Biochemistry, 46, 2007
2NWP
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STRUCTURAL AND KINETIC EFFECTS OF HYDROPHOBIC MUTATIONS IN THE ACTIVE SITE OF HUMAN CARBONIC ANHYDRASE II
分子名称:carbonic anhydrase 2, ZINC ION, SULFATE ION
著者Fisher, S.Z., McKenna, R.
登録日2006-11-16
公開日2007-04-24
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Speeding Up Proton Transfer in a Fast Enzyme: Kinetic and Crystallographic Studies on the Effect of Hydrophobic Amino Acid Substitutions in the Active Site of Human Carbonic Anhydrase II.
Biochemistry, 46, 2007
2NWY
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STRUCTURAL AND KINETIC EFFECTS OF HYDROPHOBIC MUTATIONS ON THE ACTIVE SITE OF HUMAN CARBONIC ANHYDRASE II
分子名称:carbonic anhydrase 2, ZINC ION
著者Fisher, S.Z., McKenna, R.
登録日2006-11-16
公開日2007-04-24
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Speeding Up Proton Transfer in a Fast Enzyme: Kinetic and Crystallographic Studies on the Effect of Hydrophobic Amino Acid Substitutions in the Active Site of Human Carbonic Anhydrase II.
Biochemistry, 46, 2007
2NWZ
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STRUCTURAL AND KINETIC EFFECTS OF HYDROPHOBIC MUTATIONS ON THE ACTIVE SITE OF HUMAN CARBONIC ANHYDRASE II
分子名称:carbonic anhydrase 2, ZINC ION, SULFATE ION
著者Fisher, S.Z., McKenna, R.
登録日2006-11-16
公開日2007-04-24
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Speeding Up Proton Transfer in a Fast Enzyme: Kinetic and Crystallographic Studies on the Effect of Hydrophobic Amino Acid Substitutions in the Active Site of Human Carbonic Anhydrase II.
Biochemistry, 46, 2007
2NXR
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STRUCTURAL EFFECTS OF HYDROPHOBIC MUTATIONS ON THE ACTIVE SITE OF HUMAN CARBONIC ANHYDRASE II
分子名称:carbonic anhydrase 2, ZINC ION, SULFATE ION
著者Fisher, S.Z., McKenna, R.
登録日2006-11-19
公開日2007-04-24
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Speeding Up Proton Transfer in a Fast Enzyme: Kinetic and Crystallographic Studies on the Effect of Hydrophobic Amino Acid Substitutions in the Active Site of Human Carbonic Anhydrase II.
Biochemistry, 46, 2007
2NXS
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STRUCTURAL AND KINETIC EFFECTS OF HYDROPHOBIC MUTATIONS IN THE ACTIVE SITE OF HUMAN CARBONIC ANHYDRASE II
分子名称:carbonic anhydrase 2, ZINC ION, SULFATE ION
著者Fisher, S.Z., McKenna, R.
登録日2006-11-19
公開日2007-04-24
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Speeding Up Proton Transfer in a Fast Enzyme: Kinetic and Crystallographic Studies on the Effect of Hydrophobic Amino Acid Substitutions in the Active Site of Human Carbonic Anhydrase II.
Biochemistry, 46, 2007
2NXT
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STRUCTURAL AND KINETIC EFFECTS OF HYDROPHOBIC MUTATIONS IN THE ACTIVE SITE OF HUMAN CARBONIC ANHYDRASE II
分子名称:carbonic anhydrase 2, ZINC ION
著者Fisher, S.Z., McKenna, R.
登録日2006-11-19
公開日2007-04-24
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.15 Å)
主引用文献Speeding Up Proton Transfer in a Fast Enzyme: Kinetic and Crystallographic Studies on the Effect of Hydrophobic Amino Acid Substitutions in the Active Site of Human Carbonic Anhydrase II.
Biochemistry, 46, 2007
2QA0
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STRUCTURE OF ADENO-ASSOCIATED VIRUS SEROTYPE 8
分子名称:Capsid protein, SODIUM ION
著者Nam, H.-J.
登録日2007-06-14
公開日2008-04-08
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structure of adeno-associated virus serotype 8, a gene therapy vector.
J.Virol., 81, 2007
3D92
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HUMAN CARBONIC ANHYDRASE II BOUND WITH SUBSTRATE CARBON DIOXIDE
分子名称:carbonic anhydrase II, ZINC ION, CARBON DIOXIDE, ...
著者Domsic, J.F., Avvaru, B.S., McKenna, R.
登録日2008-05-26
公開日2008-09-02
最終更新日2018-01-24
実験手法X-RAY DIFFRACTION (1.1 Å)
主引用文献Entrapment of carbon dioxide in the active site of carbonic anhydrase II
J.Biol.Chem., 283, 2008
3D93
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APO HUMAN CARBONIC ANHYDRASE II BOUND WITH SUBSTRATE CARBON DIOXIDE
分子名称:carbonic anhydrase II, CARBON DIOXIDE, GLYCEROL
著者Domsic, J.F., Avvaru, B.S., McKenna, R.
登録日2008-05-26
公開日2008-09-02
最終更新日2017-10-25
実験手法X-RAY DIFFRACTION (1.1 Å)
主引用文献Entrapment of carbon dioxide in the active site of carbonic anhydrase II
J.Biol.Chem., 283, 2008
3E78
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STRUCTURE DETERMINATION OF THE CANCER-ASSOCIATED MYCOPLASMA HYORHINIS PROTEIN MH-P37
分子名称:High affinity transport system protein p37, THIAMINE DIPHOSPHATE, CALCIUM ION, ...
著者Sippel, K.H., Robbins, A.H., Reutzel, R., Domsic, J., McKenna, R.
登録日2008-08-18
公開日2008-10-21
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structure determination of the cancer-associated Mycoplasma hyorhinis protein Mh-p37.
Acta Crystallogr.,Sect.D, 64, 2008
3E79
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STRUCTURE DETERMINATION OF THE CANCER-ASSOCIATED MYCOPLASMA HYORHINIS PROTEIN MH-P37
分子名称:High affinity transport system protein p37, 5-amino-2,4,6-triiodobenzene-1,3-dicarboxylic acid, THIAMINE DIPHOSPHATE, ...
著者Sippel, K.H., Robbins, A.H., Reutzel, R., Domsic, J., McKenna, R.
登録日2008-08-18
公開日2008-10-21
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structure determination of the cancer-associated Mycoplasma hyorhinis protein Mh-p37.
Acta Crystallogr.,Sect.D, 64, 2008
3F9Q
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RE-REFINEMENT OF UNCOMPLEXED PLASMEPSIN II FROM PLASMODIUM FALCIPARUM.
分子名称:Plasmepsin-2
著者Robbins, A.H., Mckenna, R.
登録日2008-11-14
公開日2009-03-10
最終更新日2011-11-16
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystallographic evidence for noncoplanar catalytic aspartic acids in plasmepsin II resides in the Protein Data Bank.
Acta Crystallogr.,Sect.D, 65, 2009
3GZ0
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APO-HUMAN CARBONIC ANHYDRASE II REVISITED: IMPLICATIONS OF THE LOSS OF A METAL IN PROTEIN STRUCTURE, STABILITY AND SOLVENT NETWORK
分子名称:Carbonic anhydrase 2, ZINC ION
著者Avvaru, B.S., McKenna, R.
登録日2009-04-06
公開日2009-07-21
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.26 Å)
主引用文献Apo-Human Carbonic Anhydrase II Revisited: Implications of the Loss of a Metal in Protein Structure, Stability, and Solvent Network .
Biochemistry, 48, 2009