Author results

2WRD
  • Download 2wrd
  • View 2wrd
Molmil generated image of 2wrd
STRUCTURE OF H2 JAPAN HEMAGGLUTININ
Descriptor:HEMAGGLUTININ
Authors:Liu, J., Stevens, D.J., Haire, L.F., Walker, P.A., Coombs, P.J., Russell, R.J., Gamblin, S.J., Skehel, J.J.
Deposit date:2009-09-01
Release date:2009-09-29
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:From the Cover: Structures of Receptor Complexes Formed by Hemagglutinins from the Asian Influenza Pandemic of 1957.
Proc.Natl.Acad.Sci.USA, 106, 2009
2WRE
  • Download 2wre
  • View 2wre
Molmil generated image of 2wre
STRUCTURE OF H2 JAPAN HEMAGGLUTININ WITH HUMAN RECEPTOR
Descriptor:HEMAGGLUTININ, O-SIALIC ACID, BETA-D-GALACTOSE
Authors:Liu, J., Stevens, D.J., Haire, L.F., Walker, P.A., Coombs, P.J., Russell, R.J., Gamblin, S.J., Skehel, J.J.
Deposit date:2009-09-01
Release date:2009-09-29
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.001 Å)
Cite:From the Cover: Structures of Receptor Complexes Formed by Hemagglutinins from the Asian Influenza Pandemic of 1957.
Proc.Natl.Acad.Sci.USA, 106, 2009
2WRF
  • Download 2wrf
  • View 2wrf
Molmil generated image of 2wrf
STRUCTURE OF H2 AVIAN JENA HEMAGGLUTININ WITH HUMAN RECEPTOR
Descriptor:HEMAGGLUTININ, O-SIALIC ACID, BETA-D-GALACTOSE
Authors:Liu, J., Stevens, D.J., Haire, L.F., Walker, P.A., Coombs, P.J., Russell, R.J., Gamblin, S.J., Skehel, J.J.
Deposit date:2009-09-01
Release date:2009-09-29
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:From the Cover: Structures of Receptor Complexes Formed by Hemagglutinins from the Asian Influenza Pandemic of 1957.
Proc.Natl.Acad.Sci.USA, 106, 2009
2WRG
  • Download 2wrg
  • View 2wrg
Molmil generated image of 2wrg
STRUCTURE OF H1 1918 HEMAGGLUTININ WITH HUMAN RECEPTOR
Descriptor:HEMAGGLUTININ HA1 CHAIN, HEMAGGLUTININ HA2 CHAIN, N-ACETYL-D-GLUCOSAMINE, ...
Authors:Liu, J., Stevens, D.J., Haire, L.F., Walker, P.A., Coombs, P.J., Russell, R.J., Gamblin, S.J., Skehel, J.J.
Deposit date:2009-09-01
Release date:2009-09-29
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:From the Cover: Structures of Receptor Complexes Formed by Hemagglutinins from the Asian Influenza Pandemic of 1957.
Proc.Natl.Acad.Sci.USA, 106, 2009
2WRH
  • Download 2wrh
  • View 2wrh
Molmil generated image of 2wrh
STRUCTURE OF H1 DUCK ALBERT HEMAGGLUTININ WITH HUMAN RECEPTOR
Descriptor:HEMAGGLUTININ HA1 CHAIN, HEMAGGLUTININ HA2 CHAIN, O-SIALIC ACID
Authors:Liu, J., Stevens, D.J., Haire, L.F., Walker, P.A., Coombs, P.J., Russell, R.J., Gamblin, S.J., Skehel, J.J.
Deposit date:2009-09-01
Release date:2009-09-29
Last modified:2012-11-28
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structures of Receptor Complexes Formed by Hemagglutinins from the Asian Influenza Pandemic of 1957
Proc.Natl.Acad.Sci.USA, 106, 2009
3L4Q
  • Download 3l4q
  • View 3l4q
Molmil generated image of 3l4q
STRUCTURAL INSIGHTS INTO PHOSPHOINOSITIDE 3-KINASE ACTIVATION BY THE INFLUENZA A VIRUS NS1 PROTEIN
Descriptor:Non-structural protein 1, Phosphatidylinositol 3-kinase regulatory subunit beta, GLYCEROL
Authors:Hale, B.G., Kerry, P.S., Jackson, D., Precious, B.L., Gray, A., Killip, M.J., Randall, R.E., Russell, R.J.
Deposit date:2009-12-21
Release date:2010-02-02
Last modified:2014-02-12
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural insights into phosphoinositide 3-kinase activation by the influenza A virus NS1 protein
Proc.Natl.Acad.Sci.USA, 107, 2010
3O9J
  • Download 3o9j
  • View 3o9j
Molmil generated image of 3o9j
INFLUENZA NA IN COMPLEX WITH COMPOUND 5
Descriptor:Neuraminidase, 5-(acetylamino)-2,6-anhydro-3,5-dideoxy-3-prop-2-en-1-yl-D-glycero-D-galacto-non-2-enonic acid, CALCIUM ION, ...
Authors:Russell, R.J., Kerry, P.S.
Deposit date:2010-08-04
Release date:2010-12-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.0002 Å)
Cite:Novel sialic acid derivatives lock open the 150-loop of an influenza A virus group-1 sialidase.
Nat Commun, 1, 2010
3O9K
  • Download 3o9k
  • View 3o9k
Molmil generated image of 3o9k
INFLUENZA NA IN COMPLEX WITH COMPOUND 6
Descriptor:Neuraminidase, 5-(acetylamino)-2,6-anhydro-3,5-dideoxy-3-[(2E)-3-(4-methylphenyl)prop-2-en-1-yl]-D-glycero-D-galacto-non-2-enonic acid
Authors:Russell, R.J., Kerry, P.S.
Deposit date:2010-08-04
Release date:2010-12-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4945 Å)
Cite:Novel sialic acid derivatives lock open the 150-loop of an influenza A virus group-1 sialidase.
Nat Commun, 1, 2010
3O9Q
  • Download 3o9q
  • View 3o9q
Molmil generated image of 3o9q
EFFECTOR DOMAIN OF NS1 FROM A/PR/8/34 CONTAINING A W187A MUTATION
Descriptor:Nonstructural protein 1
Authors:Kerry, P.S., Lewis, A., Hale, B.G., Hass, C., Taylor, M.A., Randall, R.E., Russell, R.J.M.
Deposit date:2010-08-04
Release date:2011-05-18
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:A Transient Homotypic Interaction Model for the Influenza A Virus NS1 Protein Effector Domain.
Plos One, 6, 2011
3O9R
  • Download 3o9r
  • View 3o9r
Molmil generated image of 3o9r
EFFECTOR DOMAIN OF NS1 FROM INFLUENZA A/PR/8/34 CONTAINING A W187A MUTATION
Descriptor:Nonstructural protein 1
Authors:Kerry, P.S., Lewis, A., Hale, B.G., Hass, C., Taylor, M.A., Randall, R.E., Russell, R.J.M.
Deposit date:2010-08-04
Release date:2011-05-11
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:A Transient Homotypic Interaction Model for the Influenza A Virus NS1 Protein Effector Domain.
Plos One, 6, 2011
3O9S
  • Download 3o9s
  • View 3o9s
Molmil generated image of 3o9s
EFFECTOR DOMAIN OF INFLUENZA A/PR/8/34 NS1
Descriptor:Nonstructural protein 1
Authors:Kerry, P.S., Lewis, A., Hale, B.G., Hass, C., Taylor, M.A., Randall, R.E., Russell, R.J.M.
Deposit date:2010-08-04
Release date:2011-05-11
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.48 Å)
Cite:A Transient Homotypic Interaction Model for the Influenza A Virus NS1 Protein Effector Domain.
Plos One, 6, 2011
3O9T
  • Download 3o9t
  • View 3o9t
Molmil generated image of 3o9t
EFFECTOR DOMAIN FROM INFLUENZA A/PR/8/34 NS1
Descriptor:Nonstructural protein 1, HEXAETHYLENE GLYCOL
Authors:Kerry, P.S., Lewis, A., Hale, B.G., Hass, C., Taylor, M.A., Randall, R.E., Russell, R.J.M.
Deposit date:2010-08-04
Release date:2011-05-11
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:A Transient Homotypic Interaction Model for the Influenza A Virus NS1 Protein Effector Domain.
Plos One, 6, 2011
3O9U
  • Download 3o9u
  • View 3o9u
Molmil generated image of 3o9u
EFFECTOR DOMAIN OF INFLUENZA A/PR/8/34 NS1
Descriptor:Nonstructural protein 1
Authors:Kerry, P.S., Lewis, A., Hale, B.G., Hass, C., Taylor, M.A., Randall, R.E., Russell, R.J.M.
Deposit date:2010-08-04
Release date:2011-05-11
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:A Transient Homotypic Interaction Model for the Influenza A Virus NS1 Protein Effector Domain.
Plos One, 6, 2011
3OA9
  • Download 3oa9
  • View 3oa9
Molmil generated image of 3oa9
EFFECTOR DOMAIN OF INFLUENZA A/DUCK/ALBANY/76 NS1
Descriptor:Non-structural protein 1
Authors:Kerry, P.S., Lewis, A., Hale, B.G., Hass, C., Taylor, M.A., Randall, R.E., Russell, R.J.M.
Deposit date:2010-08-05
Release date:2011-05-11
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:A Transient Homotypic Interaction Model for the Influenza A Virus NS1 Protein Effector Domain.
Plos One, 6, 2011
3RVC
  • Download 3rvc
  • View 3rvc
Molmil generated image of 3rvc
EFFECTOR DOMAIN OF NS1 FROM INFLUENZA A/PR/8/34 CONTAINING A W187A MUTATION
Descriptor:Non-structural protein 1
Authors:Kerry, P.S., Long, E., Taylor, M.A., Russell, R.J.M.
Deposit date:2011-05-06
Release date:2011-08-24
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Conservation of a crystallographic interface suggests a role for beta-sheet augmentation in influenza virus NS1 multifunctionality.
Acta Crystallogr.,Sect.F, 67, 2011
4D8S
  • Download 4d8s
  • View 4d8s
Molmil generated image of 4d8s
INFLUENZA NA IN COMPLEX WITH ANTIVIRAL COMPOUND
Descriptor:Neuraminidase, CALCIUM ION, pentan-3-yl 2-(acetylamino)-2,4-dideoxy-alpha-L-threo-hex-4-enopyranosiduronic acid
Authors:Kerry, P.S., Russell, R.J.M.R.
Deposit date:2012-01-11
Release date:2013-02-13
Method:X-RAY DIFFRACTION (2.398 Å)
Cite:Exploring the interactions of unsaturated glucuronides with influenza virus sialidase.
J.Med.Chem., 55, 2012
4FNG
  • Download 4fng
  • View 4fng
Molmil generated image of 4fng
THE ALPHA-ESTERASE-7 CARBOXYLESTERASE, E3, FROM THE BLOWFLY LUCILIA CUPRINA
Descriptor:E3 alpha-esterase-7 caboxylesterase
Authors:Jackson, C.J., Liu, J.-W., Carr, P.D., Younis, F., Pandey, G., Coppin, C., Meirelles, T., Ollis, D.L., Tawfik, D.S., Weik, M., Oakeshott, J.G.
Deposit date:2012-06-19
Release date:2013-06-19
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Structure and function of an insect alpha-carboxylesterase ( alpha Esterase7) associated with insecticide resistance.
Proc.Natl.Acad.Sci.USA, 110, 2013
4FNM
  • Download 4fnm
  • View 4fnm
Molmil generated image of 4fnm
THE ALPHA-ESTERASE-7 CARBOXYLESTERASE, E3, FROM THE BLOWFLY LUCILIA CUPRINA
Descriptor:E3 alpha-esterase-7 carboxylesterase, DIETHYL HYDROGEN PHOSPHATE
Authors:Jackson, C.J., Liu, J.-W., Carr, P.D., Younis, F., Pandey, G., Coppin, C., Meirelles, T., Ollis, D.L., Tawfik, D.S., Weik, M., Oakeshott, J.G.
Deposit date:2012-06-20
Release date:2013-12-04
Method:X-RAY DIFFRACTION (1.804 Å)
Cite:Structure and function of an insect alpha-carboxylesterase ( alpha Esterase7) associated with insecticide resistance.
Proc.Natl.Acad.Sci.USA, 110, 2013
4GB1
  • Download 4gb1
  • View 4gb1
Molmil generated image of 4gb1
SYNTHESIS AND EVALUATION OF NOVEL 3-C-ALKYLATED-NEU5AC2EN DERIVATIVES AS PROBES OF INFLUENZA VIRUS SIALIDASE 150-LOOP FLEXIBILITY
Descriptor:Neuraminidase, 5-(acetylamino)-2,6-anhydro-3,5-dideoxy-3-[(2E)-3-phenylprop-2-en-1-yl]-D-glycero-L-altro-non-2-enonic acid, CALCIUM ION
Authors:Kerry, P.S., Rudrawar, S., Rameix-Welti, M.-A., Maggioni, A., Dyason, J.C., Rose, F.J., van der Werf, S., Thomson, R.J., Naffakh, N., Russell, R.J.M., von Itzstein, M.
Deposit date:2012-07-26
Release date:2012-09-26
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (2.62 Å)
Cite:Synthesis and evaluation of novel 3-C-alkylated-Neu5Ac2en derivatives as probes of influenza virus sialidase 150-loop flexibility.
Org.Biomol.Chem., 10, 2012
4KS1
  • Download 4ks1
  • View 4ks1
Molmil generated image of 4ks1
INFLUENZA NEURAMINIDASE IN COMPLEX WITH ANTIVIRAL COMPOUND (3S,4R,5R)-4-(ACETYLAMINO)-3-AMINO-5-(PENTAN-3-YLOXY)CYCLOHEX-1-ENE-1-CARBOXYLIC ACID
Descriptor:Neuraminidase, CALCIUM ION, (3S,4R,5R)-4-(acetylamino)-3-amino-5-(pentan-3-yloxy)cyclohex-1-ene-1-carboxylic acid, ...
Authors:Kerry, P.S., Russell, R.J.M.
Deposit date:2013-05-17
Release date:2013-10-30
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural basis for a class of nanomolar influenza A neuraminidase inhibitors.
Sci Rep, 3, 2013
4KS3
  • Download 4ks3
  • View 4ks3
Molmil generated image of 4ks3
INFLUENZA NEURAMINIDASE IN COMPLEX WITH ANTIVIRAL COMPOUND (3S,4R,5R)-4-(ACETYLAMINO)-3-[4-(3-HYDROXYPROPYL)-1H-1,2,3-TRIAZOL-1-YL]-5-(PENTAN-3-YLOXY)CYCLOHEX-1-ENE-1-CARBOXYLIC ACID
Descriptor:Neuraminidase, (3S,4R,5R)-4-(acetylamino)-3-[4-(3-hydroxypropyl)-1H-1,2,3-triazol-1-yl]-5-(pentan-3-yloxy)cyclohex-1-ene-1-carboxylic acid, CALCIUM ION
Authors:Kerry, P.S., Russell, R.J.M.
Deposit date:2013-05-17
Release date:2013-10-30
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural basis for a class of nanomolar influenza A neuraminidase inhibitors.
Sci Rep, 3, 2013
4KS4
  • Download 4ks4
  • View 4ks4
Molmil generated image of 4ks4
INFLUENZA NEURAMINIDASE IN COMPLEX WITH ANTIVIRAL COMPOUND (3S,4R,5R)-4-(ACETYLAMINO)-3-{4-[(1R)-1-HYDROXYPROPYL]-1H-1,2,3-TRIAZOL-1-YL}-5-(PENTAN-3-YLOXY)CYCLOHEX-1-ENE-1-CARBOXYLIC ACID
Descriptor:Neuraminidase, (3S,4R,5R)-4-(acetylamino)-3-{4-[(1R)-1-hydroxypropyl]-1H-1,2,3-triazol-1-yl}-5-(pentan-3-yloxy)cyclohex-1-ene-1-carboxylic acid, CALCIUM ION
Authors:Kerry, P.S., Russell, R.J.M.
Deposit date:2013-05-17
Release date:2013-10-30
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (2.495 Å)
Cite:Structural basis for a class of nanomolar influenza A neuraminidase inhibitors.
Sci Rep, 3, 2013
4KS5
  • Download 4ks5
  • View 4ks5
Molmil generated image of 4ks5
INFLUENZA NEURAMINIDASE IN COMPLEX WITH ANTIVIRAL COMPOUND (3S,4R,5R)-4-(ACETYLAMINO)-3-[4-(2-HYDROXYPROPAN-2-YL)-1H-1,2,3-TRIAZOL-1-YL]-5-(PENTAN-3-YLOXY)CYCLOHEX-1-ENE-1-CARBOXYLIC ACID
Descriptor:Neuraminidase, CALCIUM ION, (3S,4R,5R)-4-(acetylamino)-3-[4-(2-hydroxypropan-2-yl)-1H-1,2,3-triazol-1-yl]-5-(pentan-3-yloxy)cyclohex-1-ene-1-carboxylic acid
Authors:Kerry, P.S., Russell, R.J.M.
Deposit date:2013-05-17
Release date:2013-10-30
Method:X-RAY DIFFRACTION (2.699 Å)
Cite:Structural basis for a class of nanomolar influenza A neuraminidase inhibitors.
Sci Rep, 3, 2013
4L9X
  • Download 4l9x
  • View 4l9x
Molmil generated image of 4l9x
TRIAZINE HYDROLASE FROM ARTHOBACTER AURESCENS MODIFIED FOR MAXIMUM EXPRESSION IN E.COLI
Descriptor:Triazine hydrolase, ACETATE ION
Authors:Jackson, C.J., Coppin, C.W., Alexandrov, A., Wilding, M., Liu, J.-W., Ubels, J., Paks, M., Carr, P.D., Newman, J., Russell, R.J., Field, M., Weik, M., Oakeshott, J.G., Scott, C.
Deposit date:2013-06-18
Release date:2014-05-21
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Apoenzyme stabilization results in 300-fold increased soluble production of the Zn2+-dependent dechlorinase TrzN.
Appl.Environ.Microbiol., 2014
4LH8
  • Download 4lh8
  • View 4lh8
Molmil generated image of 4lh8
TRIAZINE HYDROLASE FROM ARTHOBACTER AURESCENS MODIFIED FOR MAXIMUM EXPRESSION IN E.COLI
Descriptor:Triazine hydrolase, ZINC ION
Authors:Jackson, C.J., Coppin, C.W., Alexandrov, A., Wilding, M., Liu, J.-W., Ubels, J., Paks, M., Carr, P.D., Newman, J., Russell, R.J., Field, M., Weik, M., Oakeshott, J.G., Scott, C.
Deposit date:2013-07-01
Release date:2014-05-21
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Apoenzyme stabilization results in 300-fold increased soluble production of the Zn2+-dependent dechlorinase TrzN.
Appl.Environ.Microbiol., 2014