Author results

5C0C
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1E6 TCR IN COMPLEX WITH HLA-A02 CARRYING RQFGPDWIVA
Descriptor:HLA class I histocompatibility antigen, A-2 alpha chain, Beta-2-microglobulin, ...
Authors:Rizkallah, P.J., Bulek, A.M., Cole, D.K., Sewell, A.K.
Deposit date:2015-06-12
Release date:2016-05-04
Last modified:2016-06-08
Method:X-RAY DIFFRACTION (1.974 Å)
Cite:Hotspot autoimmune T cell receptor binding underlies pathogen and insulin peptide cross-reactivity.
J.Clin.Invest., 126, 2016
5C0D
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HLA-A02 CARRYING AQWGPDPAAA
Descriptor:HLA class I histocompatibility antigen, A-2 alpha chain, Beta-2-microglobulin, ...
Authors:Rizkallah, P.J., Bulek, A.M., Cole, D.K., Sewell, A.K.
Deposit date:2015-06-12
Release date:2016-05-04
Last modified:2016-06-08
Method:X-RAY DIFFRACTION (1.68 Å)
Cite:Hotspot autoimmune T cell receptor binding underlies pathogen and insulin peptide cross-reactivity.
J.Clin.Invest., 126, 2016
5C0E
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HLA-A02 CARRYING YLGGPDFPTI
Descriptor:HLA class I histocompatibility antigen, A-2 alpha chain, Beta-2-microglobulin, ...
Authors:Rizkallah, P.J., Bulek, A.M., Cole, D.K., Sewell, A.K.
Deposit date:2015-06-12
Release date:2016-05-04
Last modified:2016-06-08
Method:X-RAY DIFFRACTION (1.491 Å)
Cite:Hotspot autoimmune T cell receptor binding underlies pathogen and insulin peptide cross-reactivity.
J.Clin.Invest., 126, 2016
5C0F
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HLA-A02 CARRYING RQWGPDPAAV
Descriptor:HLA class I histocompatibility antigen, A-2 alpha chain, Beta-2-microglobulin, ...
Authors:Rizkallah, P.J., Bulek, A.M., Cole, D.K., Sewell, A.K.
Deposit date:2015-06-12
Release date:2016-05-04
Last modified:2016-06-08
Method:X-RAY DIFFRACTION (1.463 Å)
Cite:Hotspot autoimmune T cell receptor binding underlies pathogen and insulin peptide cross-reactivity.
J.Clin.Invest., 126, 2016
5C0G
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HLA-A02 CARRYING YLGGPDFPTI
Descriptor:HLA class I histocompatibility antigen, A-2 alpha chain, Beta-2-microglobulin, ...
Authors:Rizkallah, P.J., Bulek, A.M., Cole, D.K., Sewell, A.K.
Deposit date:2015-06-12
Release date:2016-05-04
Last modified:2016-06-08
Method:X-RAY DIFFRACTION (1.37 Å)
Cite:Hotspot autoimmune T cell receptor binding underlies pathogen and insulin peptide cross-reactivity.
J.Clin.Invest., 126, 2016
5C0I
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HAL-A02 CARRYING RQFGPDFPTI
Descriptor:HLA class I histocompatibility antigen, A-2 alpha chain, Beta-2-microglobulin, ...
Authors:Rizkallah, P.J., Bulek, A.M., Cole, D.K., Sewell, A.K.
Deposit date:2015-06-12
Release date:2016-05-04
Last modified:2016-06-08
Method:X-RAY DIFFRACTION (1.53 Å)
Cite:Hotspot autoimmune T cell receptor binding underlies pathogen and insulin peptide cross-reactivity.
J.Clin.Invest., 126, 2016
5C0J
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HLA-A02 CARRYING RQFGPDWIVA
Descriptor:HLA class I histocompatibility antigen, A-2 alpha chain, Beta-2-microglobulin, ...
Authors:Rizkallah, P.J., Bulek, A.M., Cole, D.K., Sewell, A.K.
Deposit date:2015-06-12
Release date:2016-05-04
Last modified:2016-06-08
Method:X-RAY DIFFRACTION (1.64 Å)
Cite:Hotspot autoimmune T cell receptor binding underlies pathogen and insulin peptide cross-reactivity.
J.Clin.Invest., 126, 2016
5EU3
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HLA CLASS I ANTIGEN
Descriptor:HLA class I histocompatibility antigen, A-2 alpha chain, Beta-2-microglobulin, ...
Authors:Rizkallah, P.J., Bianchi, V., Cole, D.K., Sewell, A.K.
Deposit date:2015-11-18
Release date:2016-03-02
Last modified:2016-05-11
Method:X-RAY DIFFRACTION (1.97 Å)
Cite:A Molecular Switch Abrogates Glycoprotein 100 (gp100) T-cell Receptor (TCR) Targeting of a Human Melanoma Antigen.
J.Biol.Chem., 291, 2016
5EU4
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HLA CLASS I ANTIGEN
Descriptor:HLA class I histocompatibility antigen, A-2 alpha chain, Beta-2-microglobulin, ...
Authors:Rizkallah, P.J., Bianchi, V., Cole, D.K., Sewell, A.K.
Deposit date:2015-11-18
Release date:2016-03-02
Last modified:2016-05-11
Method:X-RAY DIFFRACTION (2.12 Å)
Cite:A Molecular Switch Abrogates Glycoprotein 100 (gp100) T-cell Receptor (TCR) Targeting of a Human Melanoma Antigen.
J.Biol.Chem., 291, 2016
5EU5
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HLA CLASS I ANTIGEN
Descriptor:HLA class I histocompatibility antigen, A-2 alpha chain, Beta-2-microglobulin, ...
Authors:Rizkallah, P.J., Bianchi, V., Cole, D.K., Sewell, A.K.
Deposit date:2015-11-18
Release date:2016-03-02
Last modified:2016-05-11
Method:X-RAY DIFFRACTION (1.54 Å)
Cite:A Molecular Switch Abrogates Glycoprotein 100 (gp100) T-cell Receptor (TCR) Targeting of a Human Melanoma Antigen.
J.Biol.Chem., 291, 2016
5EU6
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HLA CLASS I ANTIGEN
Descriptor:HLA class I histocompatibility antigen, A-2 alpha chain, Beta-2-microglobulin, ...
Authors:Rizkallah, P.J., Bianchi, V., Cole, D.K., Sewell, A.K.
Deposit date:2015-11-18
Release date:2016-03-02
Last modified:2016-05-11
Method:X-RAY DIFFRACTION (2.02 Å)
Cite:A Molecular Switch Abrogates Glycoprotein 100 (gp100) T-cell Receptor (TCR) Targeting of a Human Melanoma Antigen.
J.Biol.Chem., 291, 2016
5MEN
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HUMAN LEUKOCYTE ANTIGEN A02 PRESENTING ILAKFLHWL, IN COMPLEX WITH COGNATE T-CELL RECEPTOR
Descriptor:HLA class I histocompatibility antigen, A-2 alpha chain, Beta-2-microglobulin, ...
Authors:Rizkallah, P.J., Lloyd, A., Crowther, M., Cole, D.K., Sewell, A.K.
Deposit date:2016-11-16
Release date:2016-12-07
Last modified:2017-03-22
Method:X-RAY DIFFRACTION (2.81 Å)
Cite:Structural Mechanism Underpinning Cross-reactivity of a CD8+ T-cell Clone That Recognizes a Peptide Derived from Human Telomerase Reverse Transcriptase.
J. Biol. Chem., 292, 2017
5MEO
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HUMAN LEUKOCYTE ANTIGEN PRESENTING ILGKFLHRL
Descriptor:HLA class I histocompatibility antigen, A-2 alpha chain, Beta-2-microglobulin, ...
Authors:Rizkallah, P.J., Lloyd, A., Crowther, M., Cole, D.K., Sewell, A.K.
Deposit date:2016-11-16
Release date:2016-12-07
Last modified:2017-02-01
Method:X-RAY DIFFRACTION (1.772 Å)
Cite:Structural Mechanism Underpinning Cross-reactivity of a CD8+ T-cell Clone That Recognizes a Peptide Derived from Human Telomerase Reverse Transcriptase.
J. Biol. Chem., 292, 2017
5MEP
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HUMAN LEUKOCYTE ANTIGEN A02 PRESENTING ILGKFLHWL
Descriptor:HLA class I histocompatibility antigen, A-2 alpha chain, Beta-2-microglobulin, ...
Authors:Rizkallah, P.J., Cole, D.K., Lloyd, A., Crowther, M., Sewell, A.K.
Deposit date:2016-11-16
Release date:2016-12-07
Last modified:2017-02-01
Method:X-RAY DIFFRACTION (2.71 Å)
Cite:Structural Mechanism Underpinning Cross-reactivity of a CD8+ T-cell Clone That Recognizes a Peptide Derived from Human Telomerase Reverse Transcriptase.
J. Biol. Chem., 292, 2017
5MEQ
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HUMAN LEUKOCYTE ANTIGEN A02 PRESENTING ILAKFLHTL
Descriptor:HLA class I histocompatibility antigen, A-2 alpha chain, Beta-2-microglobulin, ...
Authors:Rizkallah, P.J., Cole, D.K., Lloyd, A., Crowther, M., Sewell, A.K.
Deposit date:2016-11-16
Release date:2016-12-07
Last modified:2017-02-01
Method:X-RAY DIFFRACTION (2.27 Å)
Cite:Structural Mechanism Underpinning Cross-reactivity of a CD8+ T-cell Clone That Recognizes a Peptide Derived from Human Telomerase Reverse Transcriptase.
J. Biol. Chem., 292, 2017
5MER
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HUMAN LEUKOCYTE ANTIGEN A02 PRESENTING ILAKFLHEL
Descriptor:HLA class I histocompatibility antigen, A-2 alpha chain, Beta-2-microglobulin, ...
Authors:Rizkallah, P.J., Lloyd, A., Crowther, M., Cole, D.K., Sewell, A.K.
Deposit date:2016-11-16
Release date:2016-12-07
Last modified:2017-02-01
Method:X-RAY DIFFRACTION (1.88 Å)
Cite:Structural Mechanism Underpinning Cross-reactivity of a CD8+ T-cell Clone That Recognizes a Peptide Derived from Human Telomerase Reverse Transcriptase.
J. Biol. Chem., 292, 2017
5N1Y
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HLA-A02 CARRYING MVWGPDPLYV
Descriptor:HLA class I histocompatibility antigen, A-2 alpha chain, Beta-2-microglobulin, ...
Authors:Rizkallah, P.J., Bulek, A.M., Cole, D.K., Sewell, A.K.
Deposit date:2017-02-06
Release date:2017-02-15
Method:X-RAY DIFFRACTION (1.39 Å)
Cite:Hotspot autoimmune T cell receptor binding underlies pathogen and insulin peptide cross-reactivity.
J. Clin. Invest., 126, 2016
5N6B
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HUMAN LEUKOCYTE ANTIGEN CLASS I A02 CARRYING LLWNPGMAV
Descriptor:HLA class I histocompatibility antigen, A-2 alpha chain, Beta-2-microglobulin, ...
Authors:Rizkallah, P.J., Cole, D.K., Fuller, A., Bulek, A.M., Bovay, A.
Deposit date:2017-02-14
Release date:2017-10-18
Last modified:2018-02-21
Method:X-RAY DIFFRACTION (1.71 Å)
Cite:T cell receptor alpha variable 12-2 bias in the immunodominant response to Yellow fever virus.
Eur. J. Immunol., 48, 2018
5NMD
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868 TCR SPECIFIC FOR HLA A02 PRESENTING HIV EPITOPE SLYNTVATL
Descriptor:human T-cell Receptor alpha chain, Human T-cell Receptor, beta chain, ...
Authors:Rizkallah, P.J., Cole, D.K., Fuller, A., Sewell, A.K.
Deposit date:2017-04-05
Release date:2017-11-15
Last modified:2017-12-20
Method:X-RAY DIFFRACTION (2.07 Å)
Cite:Dual Molecular Mechanisms Govern Escape at Immunodominant HLA A2-Restricted HIV Epitope.
Front Immunol, 8, 2017
5NME
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868 TCR IN COMPLEX WITH HLA A02 PRESENTING SLYNTVATL
Descriptor:HLA class I histocompatibility antigen, A-2 alpha chain, Beta-2-microglobulin, ...
Authors:Rizkallah, P.J., Cole, D.K., Fuller, A., Sewell, A.K.
Deposit date:2017-04-05
Release date:2017-11-15
Last modified:2017-12-20
Method:X-RAY DIFFRACTION (2.94 Å)
Cite:Dual Molecular Mechanisms Govern Escape at Immunodominant HLA A2-Restricted HIV Epitope.
Front Immunol, 8, 2017
5NMF
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868 TCR IN COMPLEX WITH HLA A02 PRESENTING SLYNTIATL
Descriptor:HLA class I histocompatibility antigen, A-2 alpha chain, Beta-2-microglobulin, ...
Authors:Rizkallah, P.J., Cole, D.K., Fuller, A., Sewell, A.K.
Deposit date:2017-04-05
Release date:2017-11-15
Last modified:2017-12-20
Method:X-RAY DIFFRACTION (2.89 Å)
Cite:Dual Molecular Mechanisms Govern Escape at Immunodominant HLA A2-Restricted HIV Epitope.
Front Immunol, 8, 2017
5NMG
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868 TCR IN COMPLEX WITH HLA A02 PRESENTING SLYFNTIAVL
Descriptor:HLA class I histocompatibility antigen, A-2 alpha chain, Beta-2-microglobulin, ...
Authors:Rizkallah, P.J., Cole, D.K., Fuller, A., Sewell, A.K.
Deposit date:2017-04-05
Release date:2017-11-15
Last modified:2017-12-20
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Dual Molecular Mechanisms Govern Escape at Immunodominant HLA A2-Restricted HIV Epitope.
Front Immunol, 8, 2017
5NMH
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HLA A02 PRESENTING SLYNTIATL
Descriptor:HLA class I histocompatibility antigen, A-2 alpha chain, Beta-2-microglobulin, ...
Authors:Rizkallah, P.J., Cole, D.K., Fuller, A., Sewell, A.K.
Deposit date:2017-04-05
Release date:2017-11-15
Last modified:2017-12-20
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Dual Molecular Mechanisms Govern Escape at Immunodominant HLA A2-Restricted HIV Epitope.
Front Immunol, 8, 2017
5NMK
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HLA A02 PRESENTING SLFNTIAVL
Descriptor:HLA class I histocompatibility antigen, A-2 alpha chain, Beta-2-microglobulin, ...
Authors:Rizkallah, P.J., Cole, D.K., Fuller, A., Sewell, A.K.
Deposit date:2017-04-06
Release date:2017-11-15
Last modified:2017-12-20
Method:X-RAY DIFFRACTION (1.66 Å)
Cite:Dual Molecular Mechanisms Govern Escape at Immunodominant HLA A2-Restricted HIV Epitope.
Front Immunol, 8, 2017
6EH4
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003 HUMAN T-CELL RECEPTOR SPECIFIC FOR HIV GAG EPITOPE SLYNTVATL CARRIED BY HUMAN LEUKOCYTE ANTIGEN HLA-A*0201
Descriptor:Human T Cell Receptor Alpha Chain, Human T Cell Receptor Beta Chain, GLYCEROL, ...
Authors:Rizkallah, P.J., Cole, D.K.
Deposit date:2017-09-12
Release date:2018-04-18
Last modified:2018-05-09
Method:X-RAY DIFFRACTION (1.26 Å)
Cite:In Silicoand Structural Analyses Demonstrate That Intrinsic Protein Motions Guide T Cell Receptor Complementarity Determining Region Loop Flexibility.
Front Immunol, 9, 2018