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5LDV
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CRYSTAL STRUCTURES OF MOMP FROM CAMPYLOBACTER JEJUNI
Descriptor:MOMP porin, CALCIUM ION, PENTAETHYLENE GLYCOL, ...
Authors:Wallat, G.D., Ferrara, L.M.G., Moynie, L., Naismith, J.H.
Deposit date:2016-06-28
Release date:2016-10-26
Last modified:2016-11-09
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:MOMP from Campylobacter jejuni Is a Trimer of 18-Stranded beta-Barrel Monomers with a Ca(2+) Ion Bound at the Constriction Zone.
J.Mol.Biol., 428, 2016
4B7C
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CRYSTAL STRUCTURE OF HYPOTHETICAL PROTEIN PA1648 FROM PSEUDOMONAS AERUGINOSA.
Descriptor:PROBABLE OXIDOREDUCTASE, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID
Authors:Alphey, M.S., McMahon, S.A., Duthie, F.G., Naismith, J.H.
Deposit date:2012-08-17
Release date:2013-01-09
Last modified:2013-01-23
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:The Aeropath Project Targeting Pseudomonas Aeruginosa: Crystallographic Studies for Assessment of Potential Targets in Early-Stage Drug Discovery
Acta Crystallogr.,Sect.F, 69, 2013
4B7X
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CRYSTAL STRUCTURE OF HYPOTHETICAL PROTEIN PA1648 FROM PSEUDOMONAS AERUGINOSA.
Descriptor:PROBABLE OXIDOREDUCTASE, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
Authors:Alphey, M.S., McMahon, S.A., Duthie, F., Naismith, J.H.
Deposit date:2012-08-24
Release date:2013-01-09
Last modified:2013-01-23
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:The Aeropath Project Targeting Pseudomonas Aeruginosa: Crystallographic Studies for Assessment of Potential Targets in Early-Stage Drug Discovery
Acta Crystallogr.,Sect.F, 69, 2013
4B9A
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STRUCTURE OF A PUTATIVE EPOXIDE HYDROLASE FROM PSEUDOMONAS AERUGINOSA.
Descriptor:PROBABLE EPOXIDE HYDROLASE, SULFATE ION, GLYCEROL
Authors:Schmidberger, J.W., Schnell, R., Schneider, G.
Deposit date:2012-09-03
Release date:2013-02-06
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:The Aeropath Project Targeting Pseudomonas Aeruginosa: Crystallographic Studies for Assessment of Potential Targets in Early-Stage Drug Discovery.
Acta Crystallogr.,Sect.F, 69, 2013
4B9E
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STRUCTURE OF A PUTATIVE EPOXIDE HYDROLASE FROM PSEUDOMONAS AERUGINOSA, WITH BOUND MFA.
Descriptor:PROBABLE EPOXIDE HYDROLASE, fluoroacetic acid, SULFATE ION, ...
Authors:Schmidberger, J.W., Schnell, R., Schneider, G.
Deposit date:2012-09-04
Release date:2013-02-06
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:The Aeropath Project Targeting Pseudomonas Aeruginosa: Crystallographic Studies for Assessment of Potential Targets in Early-Stage Drug Discovery.
Acta Crystallogr.,Sect.F, 69, 2013
4ES6
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CRYSTAL STRUCTURE OF HEMD (PA5259) FROM PSEUDOMONAS AERUGINOSA (PAO1) AT 2.22 A RESOLUTION
Descriptor:Uroporphyrinogen-III synthase, CHLORIDE ION
Authors:Schnell, R., Schneider, G.
Deposit date:2012-04-22
Release date:2013-01-09
Last modified:2013-01-23
Method:X-RAY DIFFRACTION (2.22 Å)
Cite:The AEROPATH project targeting Pseudomonas aeruginosa: crystallographic studies for assessment of potential targets in early-stage drug discovery.
Acta Crystallogr.,Sect.F, 69, 2013
4ETR
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X-RAY STRUCTURE OF PA2169 FROM PSEUDOMONAS AERUGINOSA
Descriptor:Putative uncharacterized protein
Authors:Schnell, R., Sandalova, T., Lindqvist, Y., Schneider, G.
Deposit date:2012-04-24
Release date:2013-01-09
Last modified:2013-01-23
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:The AEROPATH project targeting Pseudomonas aeruginosa: crystallographic studies for assessment of potential targets in early-stage drug discovery.
Acta Crystallogr.,Sect.F, 69, 2013
4EXA
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CRYSTAL STRUCTURE OF THE PA4992, THE PUTATIVE ALDO-KETO REDUCTASE FROM PSEUDOMONA AERUGINOSA
Descriptor:Putative uncharacterized protein, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID
Authors:Sandalova, T., Schnell, R., Schneider, G.
Deposit date:2012-04-30
Release date:2013-01-09
Last modified:2019-03-20
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:The AEROPATH project targeting Pseudomonas aeruginosa: crystallographic studies for assessment of potential targets in early-stage drug discovery.
Acta Crystallogr.,Sect.F, 69, 2013
4EXB
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PUTATIVE ALDO-KETO REDUCTASE FROM PSEUDOMONA AERUGINOSA
Descriptor:Putative uncharacterized protein
Authors:Schnell, R., Schneider, G., Sandalova, T.
Deposit date:2012-04-30
Release date:2013-01-09
Last modified:2018-03-07
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:The AEROPATH project targeting Pseudomonas aeruginosa: crystallographic studies for assessment of potential targets in early-stage drug discovery.
Acta Crystallogr.,Sect.F, 69, 2013
4AFN
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CRYSTAL STRUCTURE OF 3-KETOACYL-(ACYL-CARRIER-PROTEIN) REDUCTASE (FABG) FROM PSEUDOMONAS AERUGINOSA AT 2.3A RESOLUTION
Descriptor:3-OXOACYL-[ACYL-CARRIER-PROTEIN] REDUCTASE FABG, PENTAETHYLENE GLYCOL
Authors:Cukier, C.D., Schnell, R., Schneider, G., Lindqvist, Y.
Deposit date:2012-01-20
Release date:2013-01-30
Last modified:2018-01-17
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Discovery of an Allosteric Inhibitor Binding Site in 3-Oxo-Acyl-Acp Reductase from Pseudomonas Aeruginosa
Acs Chem.Biol., 8, 2013
4AG3
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CRYSTAL STRUCTURE OF 3-KETOACYL-(ACYL-CARRIER-PROTEIN) REDUCTASE (FABG) FROM PSEUDOMONAS AERUGINOSA IN COMPLEX WITH NADPH AT 1.8A RESOLUTION
Descriptor:3-OXOACYL-[ACYL-CARRIER-PROTEIN] REDUCTASE FABG, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, PENTAETHYLENE GLYCOL
Authors:Cukier, C.D., Schnell, R., Schneider, G., Lindqvist, Y.
Deposit date:2012-01-24
Release date:2013-02-06
Last modified:2013-11-27
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Discovery of an Allosteric Inhibitor Binding Site in 3-Oxo-Acyl-Acp Reductase from Pseudomonas Aeruginosa
Acs Chem.Biol., 8, 2013
4BNT
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CRYSTAL STRUCTURE OF 3-OXOACYL-(ACYL-CARRIER-PROTEIN) REDUCTASE (FABG) FROM PSEUDOMONAS AERUGINOSA IN COMPLEX WITH 2-(TRIFLUOROMETHYL)-1H- BENZIMIDAZOLE AT 2.3A RESOLUTION
Descriptor:3-OXOACYL-[ACYL-CARRIER-PROTEIN] REDUCTASE FABG, 2-(trifluoromethyl)-1H-benzimidazole
Authors:Cukier, C.D., Schnell, R., Lindqvist, Y., Schneider, G.
Deposit date:2013-05-17
Release date:2013-09-18
Last modified:2018-01-17
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Discovery of an Allosteric Inhibitor Binding Site in 3-Oxo-Acyl-Acp Reductase from Pseudomonas Aeruginosa
Acs Chem.Biol., 8, 2013
4BNU
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CRYSTAL STRUCTURE OF 3-OXOACYL-(ACYL-CARRIER-PROTEIN) REDUCTASE (FABG) FROM PSEUDOMONAS AERUGINOSA IN COMPLEX WITH 2-PHENYL-4-(1,2,4- TRIAZOL-4-YL)QUINAZOLINE AT 2.0A RESOLUTION
Descriptor:3-OXOACYL-[ACYL-CARRIER-PROTEIN] REDUCTASE FABG, 2-phenyl-4-(1,2,4-triazol-4-yl)quinazoline
Authors:Cukier, C.D., Schnell, R., Lindqvist, Y., Schneider, G.
Deposit date:2013-05-17
Release date:2013-09-18
Last modified:2017-09-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Discovery of an Allosteric Inhibitor Binding Site in 3-Oxo-Acyl-Acp Reductase from Pseudomonas Aeruginosa
Acs Chem.Biol., 8, 2013
4BNV
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CRYSTAL STRUCTURE OF 3-OXOACYL-(ACYL-CARRIER-PROTEIN) REDUCTASE (FABG) FROM PSEUDOMONAS AERUGINOSA IN COMPLEX WITH 1-(2-CHLOROPHENYL)-3-(1- METHYLBENZIMIDAZOL-2-YL)UREA AT 2.5A RESOLUTION
Descriptor:3-OXOACYL-[ACYL-CARRIER-PROTEIN] REDUCTASE FABG, 1-(2-chlorophenyl)-3-(1-methylbenzimidazol-2-yl)urea
Authors:Cukier, C.D., Schnell, R., Lindqvist, Y., Schneider, G.
Deposit date:2013-05-17
Release date:2013-09-18
Last modified:2017-09-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Discovery of an Allosteric Inhibitor Binding Site in Resolution
Acs Chem.Biol., 8, 2013
4BNW
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CRYSTAL STRUCTURE OF 3-OXOACYL-(ACYL-CARRIER-PROTEIN) REDUCTASE (FABG) FROM PSEUDOMONAS AERUGINOSA IN COMPLEX WITH AN UNKNOWN LIGAND AT 1. 6A RESOLUTION
Descriptor:3-OXOACYL-[ACYL-CARRIER-PROTEIN] REDUCTASE FABG, DI(HYDROXYETHYL)ETHER, TETRAETHYLENE GLYCOL, ...
Authors:Cukier, C.D., Schnell, R., Lindqvist, Y., Schneider, G.
Deposit date:2013-05-17
Release date:2013-09-18
Last modified:2013-11-27
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Discovery of an Allosteric Inhibitor Binding Site in 3-Oxo-Acyl-Acp Reductase from Pseudomonas Aeruginosa
Acs Chem.Biol., 8, 2013
4BNX
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CRYSTAL STRUCTURE OF 3-OXOACYL-(ACYL-CARRIER-PROTEIN) REDUCTASE (FABG) FROM PSEUDOMONAS AERUGINOSA IN COMPLEX WITH 6-(4-(2-CHLOROANILINO)- 1H-QUINAZOLIN-2-YLIDENE)CYCLOHEXA-2, 4-DIEN-1-ONE AT 2.3A RESOLUTION
Descriptor:3-OXOACYL-[ACYL-CARRIER-PROTEIN] REDUCTASE FABG, 6-[4-(2-chloroanilino)-1H-quinazolin-2-ylidene]cyclohexa-2,4-dien-1-one
Authors:Cukier, C.D., Schnell, R., Lindqvist, Y., Schneider, G.
Deposit date:2013-05-17
Release date:2013-09-18
Last modified:2017-09-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Discovery of an Allosteric Inhibitor Binding Site in 3-Oxo-Acyl-Acp Reductase from Pseudomonas Aeruginosa
Acs Chem.Biol., 8, 2013
4BNY
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CRYSTAL STRUCTURE OF 3-OXOACYL-(ACYL-CARRIER-PROTEIN) REDUCTASE (FABG) FROM PSEUDOMONAS AERUGINOSA IN COMPLEX WITH 4-(2-PHENYLTHIENO(3,2-D) PYRIMIDIN-4-YL)MORPHOLINE AT 1.8A RESOLUTION
Descriptor:3-OXOACYL-[ACYL-CARRIER-PROTEIN] REDUCTASE FABG, 4-(2-phenylthieno[3,2-d]pyrimidin-4-yl)morpholine
Authors:Cukier, C.D., Schnell, R., Lindqvist, Y., Schneider, G.
Deposit date:2013-05-17
Release date:2013-09-18
Last modified:2013-11-27
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Discovery of an Allosteric Inhibitor Binding Site in 3-Oxo-Acyl-Acp Reductase from Pseudomonas Aeruginosa
Acs Chem.Biol., 8, 2013
4BNZ
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CRYSTAL STRUCTURE OF 3-OXOACYL-(ACYL-CARRIER-PROTEIN) REDUCTASE (FABG) FROM PSEUDOMONAS AERUGINOSA IN COMPLEX WITH 1-METHYL-N-PHENYLINDOLE- 3-CARBOXAMIDE AT 2.5A RESOLUTION
Descriptor:3-OXOACYL-[ACYL-CARRIER-PROTEIN] REDUCTASE FABG, 1-methyl-N-phenyl-indole-3-carboxamide
Authors:Cukier, C.D., Schnell, R., Lindqvist, Y., Schneider, G.
Deposit date:2013-05-17
Release date:2013-09-18
Last modified:2018-01-17
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Discovery of an Allosteric Inhibitor Binding Site in 3-Oxo-Acyl-Acp Reductase from Pseudomonas Aeruginosa
Acs Chem.Biol., 8, 2013
4BO0
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CRYSTAL STRUCTURE OF 3-OXOACYL-(ACYL-CARRIER-PROTEIN) REDUCTASE (FABG) FROM PSEUDOMONAS AERUGINOSA IN COMPLEX WITH 1-(4-METHOXY-1- METHYLINDAZOL-3-YL)-3-(2-METHOXYPHENYL)UREA AT 2.4A RESOLUTION
Descriptor:3-OXOACYL-[ACYL-CARRIER-PROTEIN] REDUCTASE FABG, 1-(4-methoxy-1-methyl-indazol-3-yl)-3-(2-methoxyphenyl)urea, NICKEL (II) ION
Authors:Cukier, C.D., Schnell, R., Lindqvist, Y., Schneider, G.
Deposit date:2013-05-17
Release date:2013-09-18
Last modified:2013-11-27
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Discovery of an Allosteric Inhibitor Binding Site in 3-Oxo-Acyl-Acp Reductase from Pseudomonas Aeruginosa
Acs Chem.Biol., 8, 2013
4BO1
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CRYSTAL STRUCTURE OF 3-OXOACYL-(ACYL-CARRIER-PROTEIN) REDUCTASE (FABG) FROM PSEUDOMONAS AERUGINOSA IN COMPLEX WITH N-(4-CHLORO-2,5- DIMETHOXYPHENYL)QUINOLINE-8-CARBOXAMIDE AT 2.2A RESOLUTION
Descriptor:3-OXOACYL-[ACYL-CARRIER-PROTEIN] REDUCTASE FABG, N-(4-CHLORO-2,5-DIMETHOXYPHENYL)QUINOLINE-8-CARBOXAMIDE
Authors:Cukier, C.D., Schnell, R., Lindqvist, Y., Schneider, G.
Deposit date:2013-05-18
Release date:2013-09-18
Last modified:2013-11-27
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Discovery of an Allosteric Inhibitor Binding Site in 3-Oxo-Acyl-Acp Reductase from Pseudomonas Aeruginosa
Acs Chem.Biol., 8, 2013
4BO2
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CRYSTAL STRUCTURE OF 3-OXOACYL-(ACYL-CARRIER-PROTEIN) REDUCTASE (FABG) FROM PSEUDOMONAS AERUGINOSA IN COMPLEX WITH 1-(1-ETHYLBENZIMIDAZOL-2- YL)-3-(2-METHOXYPHENYL)UREA AT 1.9A RESOLUTION
Descriptor:3-OXOACYL-[ACYL-CARRIER-PROTEIN] REDUCTASE FABG, 1-(1-ethylbenzimidazol-2-yl)-3-(2-methoxyphenyl)urea
Authors:Cukier, C.D., Schnell, R., Lindqvist, Y., Schneider, G.
Deposit date:2013-05-18
Release date:2013-09-18
Last modified:2013-11-27
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Discovery of an Allosteric Inhibitor Binding Site in 3-Oxo-Acyl-Acp Reductase from Pseudomonas Aeruginosa
Acs Chem.Biol., 8, 2013
4BO3
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CRYSTAL STRUCTURE OF 3-OXOACYL-(ACYL-CARRIER-PROTEIN) REDUCTASE (FABG) FROM PSEUDOMONAS AERUGINOSA IN COMPLEX WITH 2-(3-(TRIFLUOROMETHYL) ANILINO)PYRIDINE-3-SULFONAMIDE AT 2.5A RESOLUTION
Descriptor:3-OXOACYL-[ACYL-CARRIER-PROTEIN] REDUCTASE FABG, 2-(3-(trifluoromethyl)anilino)pyridine-3-sulfonamide, NICKEL (II) ION
Authors:Cukier, C.D., Schnell, R., Lindqvist, Y., Schneider, G.
Deposit date:2013-05-18
Release date:2013-09-18
Last modified:2013-11-27
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Discovery of an Allosteric Inhibitor Binding Site in 3-Oxo-Acyl-Acp Reductase from Pseudomonas Aeruginosa
Acs Chem.Biol., 8, 2013
4BO4
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CRYSTAL STRUCTURE OF 3-OXOACYL-(ACYL-CARRIER-PROTEIN) REDUCTASE (FABG) FROM PSEUDOMONAS AERUGINOSA IN COMPLEX WITH N-(2-METHOXYPHENYL)-3,4- DIHYDRO-2H-QUINOLINE-1-CARBOXAMIDE AT 2.7A RESOLUTION
Descriptor:3-OXOACYL-[ACYL-CARRIER-PROTEIN] REDUCTASE FABG, N-(2-methoxyphenyl)-3,4-dihydro-2H-quinoline-1-carboxamide
Authors:Cukier, C.D., Schnell, R., Lindqvist, Y., Schneider, G.
Deposit date:2013-05-18
Release date:2013-09-18
Last modified:2018-01-17
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Discovery of an Allosteric Inhibitor Binding Site in 3-Oxo-Acyl-Acp Reductase from Pseudomonas Aeruginosa
Acs Chem.Biol., 8, 2013
4BO5
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CRYSTAL STRUCTURE OF 3-OXOACYL-(ACYL-CARRIER-PROTEIN) REDUCTASE (FABG) FROM PSEUDOMONAS AERUGINOSA IN COMPLEX WITH N-(2-CHLOROPHENYL)-4- PYRROL-1-YL-1,3,5-TRIAZIN-2-AMINE AT 2.6A RESOLUTION
Descriptor:3-OXOACYL-[ACYL-CARRIER-PROTEIN] REDUCTASE FABG, N-(2-chlorophenyl)-4-pyrrol-1-yl-1,3,5-triazin-2-amine, NICKEL (II) ION
Authors:Cukier, C.D., Schnell, R., Lindqvist, Y., Schneider, G.
Deposit date:2013-05-18
Release date:2013-09-18
Last modified:2013-11-27
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Discovery of an Allosteric Inhibitor Binding Site in 3-Oxo-Acyl-Acp Reductase from Pseudomonas Aeruginosa
Acs Chem.Biol., 8, 2013
4BO6
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CRYSTAL STRUCTURE OF 3-OXOACYL-(ACYL-CARRIER-PROTEIN) REDUCTASE (FABG) FROM PSEUDOMONAS AERUGINOSA IN COMPLEX WITH 2,3-DIHYDROINDOL-1-YL-(2- THIOPHEN-3-YL-1,3-THIAZOL-4-YL)METHANONE AT 2.8A RESOLUTION
Descriptor:3-OXOACYL-[ACYL-CARRIER-PROTEIN] REDUCTASE FABG, 2,3-dihydroindol-1-yl-(2-thiophen-3-yl-1,3-thiazol-4-yl)methanone
Authors:Cukier, C.D., Schnell, R., Lindqvist, Y., Schneider, G.
Deposit date:2013-05-18
Release date:2013-09-18
Last modified:2018-01-17
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Discovery of an Allosteric Inhibitor Binding Site in 3-Oxo-Acyl-Acp Reductase from Pseudomonas Aeruginosa
Acs Chem.Biol., 8, 2013