Author results

2ZWZ
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ALPHA-L-FUCOSIDASE COMPLEXED WITH INHIBITOR, CORE1
分子名称:Alpha-L-fucosidase, putative, (2R,3R,4R,5R,6S)-2-(aminomethyl)-6-methylpiperidine-3,4,5-triol
著者Wu, H.-J., Ko, T.-P., Ho, C.-W., Lin, C.-H., Wang, A.H.-J.
登録日2008-12-19
公開日2009-12-08
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.36 Å)
主引用文献Structural basis of alpha-fucosidase inhibition by iminocyclitols with K(i) values in the micro- to picomolar range.
Angew.Chem.Int.Ed.Engl., 49, 2010
2ZX5
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ALPHA-L-FUCOSIDASE COMPLEXED WITH INHIBITOR, F10
分子名称:Alpha-L-fucosidase, putative, 3-(1H-indol-3-yl)-N-{[(2R,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methylpiperidin-2-yl]methyl}propanamide
著者Wu, H.-J., Ko, T.-P., Ho, C.-W., Lin, C.-H., Wang, A.H.-J.
登録日2008-12-19
公開日2009-12-08
最終更新日2017-10-11
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献Structural basis of alpha-fucosidase inhibition by iminocyclitols with K(i) values in the micro- to picomolar range.
Angew.Chem.Int.Ed.Engl., 49, 2010
2ZX6
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ALPHA-L-FUCOSIDASE COMPLEXED WITH INHIBITOR, F10-1C
分子名称:Alpha-L-fucosidase, putative, 2-(1H-indol-3-yl)-N-{[(2R,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methylpiperidin-2-yl]methyl}acetamide
著者Wu, H.-J., Ko, T.-P., Ho, C.-W., Lin, C.-H., Wang, A.H.-J.
登録日2008-12-19
公開日2009-12-08
最終更新日2017-10-11
実験手法X-RAY DIFFRACTION (2.42 Å)
主引用文献Structural basis of alpha-fucosidase inhibition by iminocyclitols with K(i) values in the micro- to picomolar range.
Angew.Chem.Int.Ed.Engl., 49, 2010
2ZX7
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ALPHA-L-FUCOSIDASE COMPLEXED WITH INHIBITOR, F10-2C
分子名称:Alpha-L-fucosidase, putative, N-{[(2R,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methylpiperidin-2-yl]methyl}-1H-indole-2-carboxamide
著者Wu, H.-J., Ko, T.-P., Ho, C.-W., Lin, C.-H., Wang, A.H.-J.
登録日2008-12-19
公開日2009-12-08
最終更新日2017-10-11
実験手法X-RAY DIFFRACTION (2.48 Å)
主引用文献Structural basis of alpha-fucosidase inhibition by iminocyclitols with K(i) values in the micro- to picomolar range.
Angew.Chem.Int.Ed.Engl., 49, 2010
2ZX8
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ALPHA-L-FUCOSIDASE COMPLEXED WITH INHIBITOR, F10-2C-O
分子名称:Alpha-L-fucosidase, putative, N-{[(2R,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methylpiperidin-2-yl]methyl}-1-benzofuran-2-carboxamide
著者Wu, H.-J., Ko, T.-P., Ho, C.-W., Lin, C.-H., Wang, A.H.-J.
登録日2008-12-19
公開日2009-12-08
最終更新日2017-10-11
実験手法X-RAY DIFFRACTION (2.33 Å)
主引用文献Structural basis of alpha-fucosidase inhibition by iminocyclitols with K(i) values in the micro- to picomolar range.
Angew.Chem.Int.Ed.Engl., 49, 2010
2ZX9
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ALPHA-L-FUCOSIDASE COMPLEXED WITH INHIBITOR, B4
分子名称:Alpha-L-fucosidase, putative, (2S)-2-cyclopentyl-2-phenyl-N-{[(2R,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methylpiperidin-2-yl]methyl}ethanamide
著者Wu, H.-J., Ko, T.-P., Ho, C.-W., Lin, C.-H., Wang, A.H.-J.
登録日2008-12-22
公開日2009-12-08
最終更新日2017-10-11
実験手法X-RAY DIFFRACTION (2.62 Å)
主引用文献Structural basis of alpha-fucosidase inhibition by iminocyclitols with K(i) values in the micro- to picomolar range.
Angew.Chem.Int.Ed.Engl., 49, 2010
2ZXA
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ALPHA-L-FUCOSIDASE COMPLEXED WITH INHIBITOR, FNJ-ACETYL
分子名称:Alpha-L-fucosidase, putative, N-{[(2R,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methylpiperidin-2-yl]methyl}acetamide
著者Wu, H.-J., Ko, T.-P., Ho, C.-W., Lin, C.-H., Wang, A.H.-J.
登録日2008-12-22
公開日2009-12-08
最終更新日2017-10-11
実験手法X-RAY DIFFRACTION (2.57 Å)
主引用文献Structural basis of alpha-fucosidase inhibition by iminocyclitols with K(i) values in the micro- to picomolar range.
Angew.Chem.Int.Ed.Engl., 49, 2010
2ZXB
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ALPHA-L-FUCOSIDASE COMPLEXED WITH INHIBITOR, PH-6FNJ
分子名称:Alpha-L-fucosidase, putative, (2S,3R,4S,5R)-2-benzylpiperidine-3,4,5-triol
著者Wu, H.-J., Ko, T.-P., Ho, C.-W., Lin, C.-H., Wang, A.H.-J.
登録日2008-12-22
公開日2009-12-08
最終更新日2017-10-11
実験手法X-RAY DIFFRACTION (2.61 Å)
主引用文献Structural basis of alpha-fucosidase inhibition by iminocyclitols with K(i) values in the micro- to picomolar range.
Angew.Chem.Int.Ed.Engl., 49, 2010
2ZXD
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ALPHA-L-FUCOSIDASE COMPLEXED WITH INHIBITOR, ISO-6FNJ
分子名称:Alpha-L-fucosidase, putative, (2S,3R,4S,5R)-2-(1-methylethyl)piperidine-3,4,5-triol
著者Wu, H.-J., Ko, T.-P., Ho, C.-W., Lin, C.-H., Wang, A.H.-J.
登録日2008-12-22
公開日2009-12-08
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Structural basis of alpha-fucosidase inhibition by iminocyclitols with K(i) values in the micro- to picomolar range.
Angew.Chem.Int.Ed.Engl., 49, 2010
3PID
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THE APO-FORM UDP-GLUCOSE 6-DEHYDROGENASE WITH A C-TERMINAL SIX-HISTIDINE TAG
分子名称:UDP-glucose 6-dehydrogenase
著者Chen, Y.-Y., Ko, T.-P., Lin, C.-H., Chen, W.-H., Wang, A.H.-J.
登録日2010-11-06
公開日2011-09-28
最終更新日2017-11-08
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Conformational change upon product binding to Klebsiella pneumoniae UDP-glucose dehydrogenase: a possible inhibition mechanism for the key enzyme in polymyxin resistance.
J.Struct.Biol., 175, 2011
3PJG
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CRYSTAL STRUCTURE OF UDP-GLUCOSE DEHYDROGENASE FROM KLEBSIELLA PNEUMONIAE COMPLEXED WITH PRODUCT UDP-GLUCURONIC ACID
分子名称:UDP-glucose 6-dehydrogenase, 3-CYCLOHEXYL-1-PROPYLSULFONIC ACID, URIDINE-5'-DIPHOSPHATE-GLUCURONIC ACID
著者Chen, Y.-Y., Ko, T.-P., Lin, C.-H., Chen, W.-H., Wang, A.H.-J.
登録日2010-11-10
公開日2011-09-28
最終更新日2017-11-08
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Conformational change upon product binding to Klebsiella pneumoniae UDP-glucose dehydrogenase: a possible inhibition mechanism for the key enzyme in polymyxin resistance.
J.Struct.Biol., 175, 2011
3PLN
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CRYSTAL STRUCTURE OF KLEBSIELLA PNEUMONIAE UDP-GLUCOSE 6-DEHYDROGENASE COMPLEXED WITH UDP-GLUCOSE
分子名称:UDP-glucose 6-dehydrogenase, URIDINE-5'-MONOPHOSPHATE
著者Chen, Y.-Y., Ko, T.-P., Lin, C.-H., Chen, W.-H., Wang, A.H.-J.
登録日2010-11-15
公開日2011-09-28
最終更新日2017-11-08
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Conformational change upon product binding to Klebsiella pneumoniae UDP-glucose dehydrogenase: a possible inhibition mechanism for the key enzyme in polymyxin resistance.
J.Struct.Biol., 175, 2011
3PLR
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CRYSTAL STRUCTURE OF KLEBSIELLA PNEUMONIAE UDP-GLUCOSE 6-DEHYDROGENASE COMPLEXED WITH NADH AND UDP-GLUCOSE
分子名称:UDP-glucose 6-dehydrogenase, 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, URIDINE-5'-MONOPHOSPHATE
著者Chen, Y.-Y., Ko, T.-P., Lin, C.-H., Chen, W.-H., Wang, A.H.-J.
登録日2010-11-15
公開日2011-09-28
最終更新日2017-11-08
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Conformational change upon product binding to Klebsiella pneumoniae UDP-glucose dehydrogenase: a possible inhibition mechanism for the key enzyme in polymyxin resistance.
J.Struct.Biol., 175, 2011
4ZHT
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CRYSTAL STRUCTURE OF UDP-GLCNAC 2-EPIMERASE
分子名称:Bifunctional UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase, URIDINE-5'-DIPHOSPHATE, CYTIDINE-5'-MONOPHOSPHATE-5-N-ACETYLNEURAMINIC ACID, ...
著者Chen, S.C., Yang, C.S., Ko, T.P., Chen, Y.
登録日2015-04-27
公開日2016-06-01
最終更新日2016-11-09
実験手法X-RAY DIFFRACTION (2.69 Å)
主引用文献Mechanism and inhibition of human UDP-GlcNAc 2-epimerase, the key enzyme in sialic acid biosynthesis.
Sci Rep, 6, 2016
3EX8
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COMPLEX STRUCTURE OF BACILLUS SUBTILIS RIBG REDUCTION MECHANISM IN RIBOFLAVIN BIOSYNTHESIS
分子名称:Riboflavin biosynthesis protein ribD, ZINC ION, [(2R,3S,4R,5E)-5-[(5-amino-2,6-dioxo-3H-pyrimidin-4-yl)imino]-2,3,4-trihydroxy-pentyl] dihydrogen phosphate
著者Chen, S.C., Lin, Y.H., Yu, H.C., Liaw, S.H.
登録日2008-10-16
公開日2008-11-04
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.56 Å)
主引用文献Complex structure of Bacillus subtilis RibG: the reduction mechanism during riboflavin biosynthesis.
J.Biol.Chem., 284, 2009
2ZE3
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CRYSTAL STRUCTURE OF DFA0005 COMPLEXED WITH ALPHA-KETOGLUTARATE: A NOVEL MEMBER OF THE ICL/PEPM SUPERFAMILY FROM ALKALI-TOLERANT DEINOCOCCUS FICUS
分子名称:DFA0005, 2-OXOGLUTARIC ACID
著者Liao, C.J., Chin, K.H., Chou, S.H.
登録日2007-12-05
公開日2008-08-12
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Crystal structure of DFA0005 complexed with alpha-ketoglutarate: a novel member of the ICL/PEPM superfamily from alkali-tolerant Deinococcus ficus
Proteins, 73, 2008
3NOA
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CRYSTAL STRUCTURE OF HUMAN PPAR-GAMMA LIGAND BINDING DOMAIN COMPLEX WITH A POTENCY IMPROVED AGONIST
分子名称:Peroxisome proliferator-activated receptor gamma, (5-{3-[4-(biphenyl-4-ylcarbonyl)-2-propylphenoxy]propoxy}-1H-indol-1-yl)acetic acid
著者Peng, Y.H., Wu, J.S., Wu, S.Y.
登録日2010-06-25
公開日2011-06-29
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.98 Å)
主引用文献Crystal structure of human PPAR-gamma ligand binding domain complex with a potency improved agonist
To be published
3SIW
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CRYSTAL STRUCTURE OF NODZ ALPHA-1,6-FUCOSYLTRANSFERASE CO-CRYSTALLIZED WITH GDP
分子名称:Nodulation fucosyltransferase NodZ, GUANOSINE-5'-DIPHOSPHATE, PHOSPHATE ION
著者Brzezinski, K., Dauter, Z., Jaskolski, M.
登録日2011-06-20
公開日2012-02-08
最終更新日2017-11-08
実験手法X-RAY DIFFRACTION (1.98 Å)
主引用文献Structures of NodZ alpha-1,6-fucosyltransferase in complex with GDP and GDP-fucose
Acta Crystallogr.,Sect.D, 68, 2012
3SIX
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CRYSTAL STRUCTURE OF NODZ ALPHA-1,6-FUCOSYLTRANSFERASE SOAKED WITH GDP-FUCOSE
分子名称:Nodulation fucosyltransferase NodZ, GUANOSINE-5'-DIPHOSPHATE, PHOSPHATE ION, ...
著者Brzezinski, K., Dauter, Z., Jaskolski, M.
登録日2011-06-20
公開日2012-02-08
最終更新日2017-11-08
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Structures of NodZ alpha-1,6-fucosyltransferase in complex with GDP and GDP-fucose
Acta Crystallogr.,Sect.D, 68, 2012
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