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7PHS
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BU of 7phs by Molmil
highly potent IL6 antagonistic antibody selected from a camelid immune phage display repertoire
Descriptor: Heavy chain of Fab129D3, Light chain of Fab129D3
Authors:Cambillau, C, Pannecoucke, E, De Haard, H.
Deposit date:2021-08-18
Release date:2022-09-07
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.77 Å)
Cite:Non-promiscuous pairing in a highly potent IL6 antagonistic antibody selected from a camelid immune phage display repertoire
To Be Published
5M38
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BU of 5m38 by Molmil
Structure of the TagL peptidoglycan binding domain from EAEC T6SS
Descriptor: OmpA family protein
Authors:Cambillau, C, Nguyen, V.S, Spinelli, S, Cascales, E.
Deposit date:2016-10-14
Release date:2018-02-21
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structure of the TagL peptidoglycan binding domain from EAEC T6SS
To Be Published
1U0Q
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BU of 1u0q by Molmil
Structure of a Llama VHH domain raised against a carbazole molecule
Descriptor: immunoglobulin heavy chain variable domain
Authors:Cambillau, C, Spinelli, S, Desmyter, A, Verrips, T.
Deposit date:2004-07-14
Release date:2005-06-28
Last modified:2019-12-25
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Crystal Structure of a Llama VHH Domain Raised Against a Carbazole Hapten
TO BE PUBLISHED
1N8O
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BU of 1n8o by Molmil
Crystal structure of a complex between bovine chymotrypsin and ecotin
Descriptor: Chymotrypsin A, A chain, C chain, ...
Authors:Cambillau, C, Spinelli, S, Lauwereys, M.
Deposit date:2002-11-21
Release date:2002-12-18
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal Structure of a Complex Between Bovine Chymotrypsin and Ecotin at 2.0 A Resolution
To be Published
8BOZ
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BU of 8boz by Molmil
structure of the Adherent-Invasive Escherichia coli Tle3/Tli3 T6SS effector/immunity complex
Descriptor: CALCIUM ION, Lipoprotein, Transmembrane protein
Authors:Cambillau, C, Roussel, A.
Deposit date:2022-11-15
Release date:2023-02-08
Method:X-RAY DIFFRACTION (3.6 Å)
Cite:Activity and Crystal Structure of the Adherent-Invasive Escherichia coli Tle3/Tli3 T6SS Effector/Immunity Complex Determined Using an AlphaFold2 Predicted Model.
Int J Mol Sci, 24, 2023
7NYJ
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BU of 7nyj by Molmil
Structure of OBP1 from Varroa destructor, form P3<2>21
Descriptor: CALCIUM ION, Odorant Binding Protein 1 from Varoa destructor, form P3<2>21, ...
Authors:Cambillau, C, Amigues, B, Roussel, A, Leone, P, Gaubert, A, Pelosi, P.
Deposit date:2021-03-22
Release date:2021-07-07
Method:X-RAY DIFFRACTION (1.81 Å)
Cite:A new non-classical fold of varroa odorant-binding proteins reveals a wide open internal cavity.
Sci Rep, 11, 2021
7NZA
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BU of 7nza by Molmil
Structure of OBP1 from Varroa destructor, form P2<1>
Descriptor: 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, Odorant Binding Protein from Varroa destructor, form P2<1>, ...
Authors:Cambillau, C, Amigues, B, Roussel, A, Leone, P, Gaubert, A, Pelosi, P.
Deposit date:2021-03-23
Release date:2021-07-07
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.199 Å)
Cite:A new non-classical fold of varroa odorant-binding proteins reveals a wide open internal cavity.
Sci Rep, 11, 2021
6FVJ
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BU of 6fvj by Molmil
TesA a major thioesterase from Mycobacterium tuberculosis
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, CALCIUM ION, Thioesterase, ...
Authors:Cambillau, C, Nguyen, V.S, Canaan, S.
Deposit date:2018-03-03
Release date:2018-10-24
Last modified:2018-12-19
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Biochemical and Structural Characterization of TesA, a Major Thioesterase Required for Outer-Envelope Lipid Biosynthesis in Mycobacterium tuberculosis.
J. Mol. Biol., 430, 2018
6FW5
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BU of 6fw5 by Molmil
TesA a major thioesterase from Mycobacterium tuberculosis
Descriptor: PHOSPHATE ION, Probable thioesterase TesA
Authors:Cambillau, C, Nguyen, V.S, Canaan, S.
Deposit date:2018-03-05
Release date:2018-10-24
Last modified:2019-01-23
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Biochemical and Structural Characterization of TesA, a Major Thioesterase Required for Outer-Envelope Lipid Biosynthesis in Mycobacterium tuberculosis.
J. Mol. Biol., 430, 2018
6EYY
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BU of 6eyy by Molmil
Anti-CRISPR AcrIIa6 cubic form
Descriptor: AcrIIa6
Authors:Cambillau, C, Amigues, B, Moineau, S.
Deposit date:2017-11-13
Release date:2018-06-06
Last modified:2019-08-14
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Widespread anti-CRISPR proteins in virulent bacteriophages inhibit a range of Cas9 proteins.
Nat Commun, 9, 2018
6EYX
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BU of 6eyx by Molmil
Anti-CRISPR AcrIIa6 tetragonal form
Descriptor: AcrIIa6
Authors:Cambillau, C, Amigues, B, Moineau, S.
Deposit date:2017-11-13
Release date:2018-06-06
Last modified:2018-08-08
Method:X-RAY DIFFRACTION (1.96 Å)
Cite:Widespread anti-CRISPR proteins in virulent bacteriophages inhibit a range of Cas9 proteins.
Nat Commun, 9, 2018
2F0C
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BU of 2f0c by Molmil
Structure of the Receptor Binding Protein (ORF49, bbp) from lactophage tp901-1
Descriptor: GLYCEROL, Phage tp901-1 ORF49 (BPP)
Authors:Cambillau, C, Spinelli, S.
Deposit date:2005-11-13
Release date:2006-03-28
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Modular structure of the receptor binding proteins of Lactococcus lactis phages. The RBP structure of the temperate phage TP901-1.
J.Biol.Chem., 281, 2006
1FFD
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BU of 1ffd by Molmil
CONTRIBUTION OF CUTINASE SERINE 42 SIDE CHAIN TO THE STABILIZATION OF THE OXYANION TRANSITION STATE
Descriptor: CUTINASE
Authors:Cambillau, C, Martinez, C, Nicolas, A.
Deposit date:1995-10-07
Release date:1996-03-08
Last modified:2021-11-03
Method:X-RAY DIFFRACTION (1.69 Å)
Cite:Contribution of cutinase serine 42 side chain to the stabilization of the oxyanion transition state.
Biochemistry, 35, 1996
1FFB
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BU of 1ffb by Molmil
CONTRIBUTION OF CUTINASE SERINE 42 SIDE CHAIN TO THE STABILIZATION OF THE OXYANION TRANSITION STATE
Descriptor: CUTINASE
Authors:Cambillau, C, Martinez, C, Nicolas, A.
Deposit date:1995-10-07
Release date:1996-03-08
Last modified:2021-11-03
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Contribution of cutinase serine 42 side chain to the stabilization of the oxyanion transition state.
Biochemistry, 35, 1996
1FFC
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BU of 1ffc by Molmil
CONTRIBUTION OF CUTINASE SERINE 42 SIDE CHAIN TO THE STABILIZATION OF THE OXYANION TRANSITION STATE
Descriptor: CUTINASE
Authors:Cambillau, C, Martinez, C, Nicolas, A.
Deposit date:1995-10-07
Release date:1996-03-08
Last modified:2021-11-03
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Contribution of cutinase serine 42 side chain to the stabilization of the oxyanion transition state.
Biochemistry, 35, 1996
1FFA
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BU of 1ffa by Molmil
CONTRIBUTION OF CUTINASE SERINE 42 SIDE CHAIN TO THE STABILIZATION OF THE OXYANION TRANSITION STATE
Descriptor: CUTINASE
Authors:Cambillau, C, Martinez, C, Nicolas, A.
Deposit date:1995-10-07
Release date:1996-03-08
Last modified:2021-11-03
Method:X-RAY DIFFRACTION (1.69 Å)
Cite:Contribution of cutinase serine 42 side chain to the stabilization of the oxyanion transition state.
Biochemistry, 35, 1996
2A9M
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BU of 2a9m by Molmil
Structural Analysis of a Tight-binding Fluorescein-scFv; apo form
Descriptor: fluorescein-scfv heavy chain, fluorescein-scfv light chain
Authors:Cambillau, C, Spinelli, S, Honegger, A, Pluckthun, A.
Deposit date:2005-07-12
Release date:2005-10-25
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:A mutation designed to alter crystal packing permits structural analysis of a tight-binding fluorescein-scFv complex.
Protein Sci., 14, 2005
2A9N
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BU of 2a9n by Molmil
A Mutation Designed to Alter Crystal Packing Permits Structural Analysis of a Tight-binding Fluorescein-scFv complex
Descriptor: 4-(2,7-DIFLUORO-6-HYDROXY-3-OXO-3H-XANTHEN-9-YL)ISOPHTHALIC ACID, fluorescein-scfv heavy chain, fluorescein-scfv light chain
Authors:Cambillau, C, Spinelli, S, Honegger, A, Pluckthun, A.
Deposit date:2005-07-12
Release date:2005-10-25
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (3 Å)
Cite:A mutation designed to alter crystal packing permits structural analysis of a tight-binding fluorescein-scFv complex.
Protein Sci., 14, 2005
1FFE
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BU of 1ffe by Molmil
CONTRIBUTION OF CUTINASE SERINE 42 SIDE CHAIN TO THE STABILIZATION OF THE OXYANION TRANSITION STATE
Descriptor: CUTINASE
Authors:Cambillau, C, Martinez, C, Nicolas, A.
Deposit date:1995-10-07
Release date:1996-03-08
Last modified:2021-11-03
Method:X-RAY DIFFRACTION (1.69 Å)
Cite:Contribution of cutinase serine 42 side chain to the stabilization of the oxyanion transition state.
Biochemistry, 35, 1996
5M2J
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BU of 5m2j by Molmil
Complex between human TNF alpha and Llama VHH2
Descriptor: Anti-(ED-B) scFV, Tumor necrosis factor
Authors:Cambillau, C, Spinelli, S, Desmyter, A, de Haard, H.
Deposit date:2016-10-13
Release date:2017-08-30
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Bivalent Llama Single-Domain Antibody Fragments against Tumor Necrosis Factor Have Picomolar Potencies due to Intramolecular Interactions.
Front Immunol, 8, 2017
5M2M
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BU of 5m2m by Molmil
Complex between human TNF alpha and Llama VHH3
Descriptor: Llama nanobody VHH3, Tumor necrosis factor
Authors:Cambillau, C, Spinelli, S, Desmyter, A, de Haard, H.
Deposit date:2016-10-13
Release date:2017-08-30
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Bivalent Llama Single-Domain Antibody Fragments against Tumor Necrosis Factor Have Picomolar Potencies due to Intramolecular Interactions.
Front Immunol, 8, 2017
5M2Y
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BU of 5m2y by Molmil
Structure of TssK C-terminal domain from E. coli T6SS
Descriptor: TssK C
Authors:Cambillau, C, Nguyen, V.S, Spinelli, S, Desmyter, A, Legrand, P.
Deposit date:2016-10-13
Release date:2017-06-28
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.61 Å)
Cite:Type VI secretion TssK baseplate protein exhibits structural similarity with phage receptor-binding proteins and evolved to bind the membrane complex.
Nat Microbiol, 2, 2017
5M2I
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BU of 5m2i by Molmil
Structure of human Tumor Necrosis Factor (TNF) in complex with the Llama VHH1
Descriptor: Tumor necrosis factor, VHH1
Authors:Cambillau, C, Spinelli, S, Desmyter, A, de Haard, H.
Deposit date:2016-10-13
Release date:2017-08-30
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Bivalent Llama Single-Domain Antibody Fragments against Tumor Necrosis Factor Have Picomolar Potencies due to Intramolecular Interactions.
Front Immunol, 8, 2017
5M2W
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BU of 5m2w by Molmil
Structure of nanobody nb18 raised against TssK from E. coli T6SS
Descriptor: Llama nanobody nb8 against TssK from T6SS, SULFATE ION
Authors:Cambillau, C, Nguyen, V.S, Spinelli, S, Desmyter, A.
Deposit date:2016-10-13
Release date:2017-06-28
Last modified:2017-08-30
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Type VI secretion TssK baseplate protein exhibits structural similarity with phage receptor-binding proteins and evolved to bind the membrane complex.
Nat Microbiol, 2, 2017
5MWN
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BU of 5mwn by Molmil
Structure of the EAEC T6SS component TssK N-terminal domain in complex with llama nanobodies nbK18 and nbK27
Descriptor: PHOSPHATE ION, Type VI secretion protein, llama nanobody raised against TssK, ...
Authors:Cambillau, C, Nguyen, V.S, Spinelli, S, Legrand, P.
Deposit date:2017-01-18
Release date:2017-06-28
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Type VI secretion TssK baseplate protein exhibits structural similarity with phage receptor-binding proteins and evolved to bind the membrane complex.
Nat Microbiol, 2, 2017

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