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2IYA
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BU of 2iya by Molmil
The crystal structure of macrolide glycosyltransferases: A blueprint for antibiotic engineering
Descriptor: (3S,5R,6S,7R,8R,11R,12S,13R,14S,15S)-6-HYDROXY-5,7,8,11,13,15-HEXAMETHYL-4,10-DIOXO-14-{[3,4,6-TRIDEOXY-3-(DIMETHYLAMINO)-BETA-D-XYLO-HEXOPYRANOSYL]OXY}-1,9-DIOXASPIRO[2.13]HEXADEC-12-YL 2,6-DIDEOXY-3-O-METHYL-ALPHA-L-ARABINO-HEXOPYRANOSIDE, OLEANDOMYCIN GLYCOSYLTRANSFERASE, URIDINE-5'-DIPHOSPHATE
Authors:Bolam, D.N, Roberts, S.M, Proctor, M.R, Turkenburg, J.P, Dodson, E.J, Martinez-Fleites, C, Yang, M, Davis, B.G, Davies, G.J, Gilbert, H.J.
Deposit date:2006-07-13
Release date:2007-03-27
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:The Crystal Structure of Two Macrolide Glycosyltransferases Provides a Blueprint for Host Cell Antibiotic Immunity.
Proc.Natl.Acad.Sci.USA, 104, 2007
2IYF
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BU of 2iyf by Molmil
The crystal structure of macrolide glycosyltransferases: A blueprint for antibiotic engineering
Descriptor: ERYTHROMYCIN A, MAGNESIUM ION, OLEANDOMYCIN GLYCOSYLTRANSFERASE, ...
Authors:Bolam, D.N, Roberts, S.M, Proctor, M.R, Turkenburg, J.P, Dodson, E.J, Martinez-Fleites, C, Yang, M, Davis, B.G, Davies, G.J, Gilbert, H.J.
Deposit date:2006-07-17
Release date:2007-03-27
Last modified:2013-08-07
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:The Crystal Structure of Two Macrolide Glycosyltransferases Provides a Blueprint for Host Cell Antibiotic Immunity.
Proc.Natl.Acad.Sci.USA, 104, 2007
1HEJ
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BU of 1hej by Molmil
C-terminal xylan binding domain from Cellulomonas fimi xylanase 11A
Descriptor: ENDO-1,4-BETA-XYLANASE D
Authors:Simpson, P.J, Hefang, X, Bolam, D.N, White, P, Hancock, S.M, Gilbert, H.J, Williamson, M.P.
Deposit date:2000-11-22
Release date:2001-05-10
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Evidence for Synergy between Family 2B Carbohydrate Binding Modules in Cellulomonas Fimi Xylanase 11A
Biochemistry, 40, 2001
1HEH
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BU of 1heh by Molmil
C-terminal xylan binding domain from Cellulomonas fimi xylanase 11A
Descriptor: ENDO-1,4-BETA-XYLANASE D
Authors:Simpson, P.J, Hefang, X, Bolam, D.N, White, P, Hancock, S.M, Gilbert, H.J, Williamson, M.P.
Deposit date:2000-11-22
Release date:2001-05-10
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Evidence for Synergy between Family 2B Carbohydrate Binding Modules in Cellulomonas Fimi Xylanase 11A
Biochemistry, 40, 2001
4UFC
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BU of 4ufc by Molmil
Crystal structure of the GH95 enzyme BACOVA_03438
Descriptor: CACODYLATE ION, CALCIUM ION, GH95, ...
Authors:Rogowski, A, Briggs, J.A, Mortimer, J.C, Tryfona, T, Terrapon, N, Lowe, E.C, Basle, A, Morland, C, Day, A.M, Zheng, H, Rogers, T.E, Thompson, P, Hawkins, A.R, Yadav, M.P, Henrissat, B, Martens, E.C, Dupree, P, Gilbert, H.J, Bolam, D.N.
Deposit date:2015-03-16
Release date:2015-07-08
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.81 Å)
Cite:Glycan Complexity Dictates Microbial Resource Allocation in the Large Intestine.
Nat.Commun., 6, 2015
5G2T
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BU of 5g2t by Molmil
BT1596 in complex with its substrate 4,5 unsaturated uronic acid alpha 1,4 D-Glucosamine-2-N, 6-O-disulfate
Descriptor: 1,2-ETHANEDIOL, 2-O GLYCOSAMINOGLYCAN SULFATASE, 4-deoxy-2-O-sulfo-alpha-L-threo-hex-4-enopyranuronic acid, ...
Authors:Cartmell, A, Lowe, E.C, Basle, A, Crouch, L.I, Czjzek, M, Turnbull, J, Henrissat, B, Terrapon, N, Thomas, S, Murray, H, Firbank, S.J, Bolam, D.N.
Deposit date:2016-04-13
Release date:2017-05-24
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:How members of the human gut microbiota overcome the sulfation problem posed by glycosaminoglycans.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5G2V
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BU of 5g2v by Molmil
Structure of BT4656 in complex with its substrate D-Glucosamine-2-N, 6-O-disulfate.
Descriptor: 2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose, CALCIUM ION, N-ACETYLGLUCOSAMINE-6-SULFATASE, ...
Authors:Cartmell, A, Lowe, E.C, Basle, A, Crouch, L.I, Czjzek, M, Turnbull, J, Henrissat, B, Terrapon, N, Thomas, S, Murray, H, Firbank, S.J, Bolam, D.N.
Deposit date:2016-04-14
Release date:2017-05-24
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (1.39 Å)
Cite:How members of the human gut microbiota overcome the sulfation problem posed by glycosaminoglycans.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
1E5B
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BU of 1e5b by Molmil
Internal xylan binding domain from C. fimi Xyn10A, R262G mutant
Descriptor: XYLANASE D
Authors:Simpson, P.J, Hefang, X, Bolam, D.N, Gilbert, H.J, Williamson, M.P.
Deposit date:2000-07-24
Release date:2001-05-25
Last modified:2018-10-24
Method:SOLUTION NMR
Cite:The Structural Basis for the Ligand Specificity of Family 2 Carbohydrate Binding Nodules
J.Biol.Chem., 275, 2000
1E5C
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BU of 1e5c by Molmil
Internal xylan binding domain from C. fimi Xyn10A, R262G mutant
Descriptor: XYLANASE D
Authors:Simpson, P.J, Hefang, X, Bolam, D.N, Gilbert, H.J, Williamson, M.P.
Deposit date:2000-07-24
Release date:2001-05-25
Last modified:2018-10-24
Method:SOLUTION NMR
Cite:The Structural Basis for the Ligand Specificity of Family 2 Carbohydrate Binding Nodules
J.Biol.Chem., 275, 2000
1GNY
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BU of 1gny by Molmil
xylan-binding module CBM15
Descriptor: SODIUM ION, XYLANASE 10C, beta-D-xylopyranose-(1-4)-beta-D-xylopyranose-(1-4)-beta-D-xylopyranose-(1-4)-beta-D-xylopyranose-(1-4)-beta-D-xylopyranose
Authors:Szabo, S, Jamal, S, Xie, H, Charnock, S.J, Bolam, D.N, Gilbert, H.J, Davies, G.J.
Deposit date:2001-10-10
Release date:2001-11-29
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (1.63 Å)
Cite:Structure of a Family 15 Carbohydrate-Binding Module in Complex with Xylopentaose: Evidence that Xylan Binds in an Approximate Three-Fold Helical Conformation
J.Biol.Chem., 276, 2001
1H6X
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BU of 1h6x by Molmil
The role of conserved amino acids in the cleft of the C-terminal family 22 carbohydrate binding module of Clostridium thermocellum Xyn10B in ligand binding
Descriptor: CALCIUM ION, ENDO-1,4-BETA-XYLANASE Y
Authors:Xie, H, Bolam, D.N, Charnock, S.J, Davies, G.J, Williamson, M.P, Simpson, P.J, Fontes, C.M.G.A, Ferreira, L.M.A, Gilbert, H.J.
Deposit date:2001-06-29
Release date:2002-06-27
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Clostridium Thermocellum Xyn10B Carbohydrate-Binding Module 22-2: The Role of Conserved Amino Acids in Ligand Binding
Biochemistry, 40, 2001
1H6Y
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BU of 1h6y by Molmil
The role of conserved amino acids in the cleft of the C-terminal family 22 carbohydrate binding module of Clostridium thermocellum Xyn10B in ligand binding
Descriptor: CALCIUM ION, ENDO-1,4-BETA-XYLANASE Y
Authors:Xie, H, Bolam, D.N, Charnock, S.J, Davies, G.J, Williamson, M.P, Simpson, P.J, Fontes, C.M.G.A, Ferreira, L.M.A, Gilbert, H.J.
Deposit date:2001-06-29
Release date:2002-06-27
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Clostridium Thermocellum Xyn10B Carbohydrate-Binding Module 22-2: The Role of Conserved Amino Acids in Ligand Binding
Biochemistry, 40, 2001
6T2P
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BU of 6t2p by Molmil
Prominent members of the human gut microbiota express endo-acting O-glycanases to initiate mucin breakdown
Descriptor: 1,2-ETHANEDIOL, CALCIUM ION, Glycosyl hydrolase family 16
Authors:Crouch, L.I, Liberato, M.V, Ubranowicz, P.A, Basle, A, Lamb, C.A, Cooke, K, Doona, M, Needham, S, Brady, R.R, Berrington, J.E, Madubic, K, Chater, P, Zhang, F, Linhardt, R.J, Spence, D.I.R, Bolam, D.N.
Deposit date:2019-10-09
Release date:2020-07-08
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Prominent members of the human gut microbiota express endo-acting O-glycanases to initiate mucin breakdown.
Nat Commun, 11, 2020
6T2O
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BU of 6t2o by Molmil
Prominent members of the human gut microbiota express endo-acting O-glycanases to initiate mucin breakdown
Descriptor: 1,2-ETHANEDIOL, CALCIUM ION, Glycosyl hydrolase family 16
Authors:Crouch, L.I, Liberato, M.V, Ubranowicz, P.A, Basle, A, Lamb, C.A, Cooke, K, Doona, M, Needham, S, Brady, R.R, Berrington, J.E, Madubic, K, Chater, P, Zhang, F, Linhardt, R.J, Spence, D.I.R, Bolam, D.N.
Deposit date:2019-10-09
Release date:2020-07-08
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Prominent members of the human gut microbiota express endo-acting O-glycanases to initiate mucin breakdown.
Nat Commun, 11, 2020
6T2S
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BU of 6t2s by Molmil
Prominent members of the human gut microbiota express endo-acting O-glycanases to initiate mucin breakdown
Descriptor: Glycoside hydrolase family 16 protein, beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-3)-beta-D-galactopyranose
Authors:Crouch, L.I, Liberato, M.V, Ubranowicz, P.A, Basle, A, Lamb, C.A, Cooke, K, Doona, M, Needham, S, Brady, R.R, Berrington, J.E, Madubic, K, Chater, P, Zhang, F, Linhardt, R.J, Spence, D.I.R, Bolam, D.N.
Deposit date:2019-10-09
Release date:2020-07-08
Last modified:2020-08-26
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Prominent members of the human gut microbiota express endo-acting O-glycanases to initiate mucin breakdown.
Nat Commun, 11, 2020
6T2R
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BU of 6t2r by Molmil
Prominent members of the human gut microbiota express endo-acting O-glycanases to initiate mucin breakdown
Descriptor: Beta-glycosidase, SULFATE ION
Authors:Crouch, L.I, Liberato, M.V, Ubranowicz, P.A, Basle, A, Lamb, C.A, Cooke, K, Doona, M, Needham, S, Brady, R.R, Berrington, J.E, Madubic, K, Chater, P, Zhang, F, Linhardt, R.J, Spence, D.I.R, Bolam, D.N.
Deposit date:2019-10-09
Release date:2020-07-08
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Prominent members of the human gut microbiota express endo-acting O-glycanases to initiate mucin breakdown.
Nat Commun, 11, 2020
6T2Q
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BU of 6t2q by Molmil
Prominent members of the human gut microbiota express endo-acting O-glycanases to initiate mucin breakdown
Descriptor: 1,2-ETHANEDIOL, CALCIUM ION, Glycosyl hydrolase family 16, ...
Authors:Crouch, L.I, Liberato, M.V, Ubranowicz, P.A, Basle, A, Lamb, C.A, Cooke, K, Doona, M, Needham, S, Brady, R.R, Berrington, J.E, Madubic, K, Chater, P, Zhang, F, Linhardt, R.J, Spence, D.I.R, Bolam, D.N.
Deposit date:2019-10-09
Release date:2020-07-08
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2 Å)
Cite:Prominent members of the human gut microbiota express endo-acting O-glycanases to initiate mucin breakdown.
Nat Commun, 11, 2020
6T2N
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BU of 6t2n by Molmil
Prominent members of the human gut microbiota express endo-acting O-glycanases to initiate mucin breakdown
Descriptor: CALCIUM ION, Glycoside hydrolase family 16 protein
Authors:Crouch, L.I, Liberato, M.V, Ubranowicz, P.A, Basle, A, Lamb, C.A, Cooke, K, Doona, M, Needham, S, Brady, R.R, Berrington, J.E, Madubic, K, Chater, P, Zhang, F, Linhardt, R.J, Spence, D.I.R, Bolam, D.N.
Deposit date:2019-10-09
Release date:2020-07-08
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Prominent members of the human gut microbiota express endo-acting O-glycanases to initiate mucin breakdown.
Nat Commun, 11, 2020
2IW1
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BU of 2iw1 by Molmil
Crystal Structure of WaaG, a glycosyltransferase involved in lipopolysaccharide biosynthesis
Descriptor: LIPOPOLYSACCHARIDE CORE BIOSYNTHESIS PROTEIN RFAG, URIDINE-5'-DIPHOSPHATE-2-DEOXY-2-FLUORO-ALPHA-D-GLUCOSE
Authors:Martinez-Fleites, C, Proctor, M, Roberts, S, Bolam, D.N, Gilbert, H.J, Davies, G.J.
Deposit date:2006-06-23
Release date:2006-10-11
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Insights Into the Synthesis of Lipopolysaccharide and Antibiotics Through the Structures of Two Retaining Glycosyltransferases from Family Gt4
Chem.Biol., 13, 2006
2IV7
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BU of 2iv7 by Molmil
Crystal Structure of WaaG, a glycosyltransferase involved in lipopolysaccharide biosynthesis
Descriptor: LIPOPOLYSACCHARIDE CORE BIOSYNTHESIS PROTEIN RFAG, URIDINE-5'-DIPHOSPHATE
Authors:Martinez-Fleites, C, Proctor, M, Roberts, S, Bolam, D.N, Gilbert, H.J, Davies, G.J.
Deposit date:2006-06-08
Release date:2006-10-11
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Insights Into the Synthesis of Lipopolysaccharide and Antibiotics Through the Structures of Two Retaining Glycosyltransferases from Family Gt4
Chem.Biol., 13, 2006
2IUY
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BU of 2iuy by Molmil
Crystal structure of AviGT4, a glycosyltransferase involved in Avilamycin A biosynthesis
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, GLYCOSYLTRANSFERASE, SULFATE ION
Authors:Martinez-Fleites, C, Proctor, M, Roberts, S, Bolam, D.N, Gilbert, H.J, Davies, G.J.
Deposit date:2006-06-08
Release date:2006-10-11
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Insights Into the Synthesis of Lipopolysaccharide and Antibiotics Through the Structures of Two Retaining Glycosyltransferases from Family Gt4
Chem.Biol., 13, 2006
2IV3
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BU of 2iv3 by Molmil
Crystal structure of AviGT4, a glycosyltransferase involved in Avilamycin A biosynthesis
Descriptor: GLYCEROL, GLYCOSYLTRANSFERASE, URIDINE-5'-DIPHOSPHATE
Authors:Martinez-Fleites, C, Proctor, M, Roberts, S, Bolam, D.N, Gilbert, H.J, Davies, G.J.
Deposit date:2006-06-08
Release date:2006-10-11
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Insights Into the Synthesis of Lipopolysaccharide and Antibiotics Through the Structures of Two Retaining Glycosyltransferases from Family Gt4
Chem.Biol., 13, 2006
4A2M
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BU of 4a2m by Molmil
Structure of the periplasmic domain of the heparin and heparan sulphate sensing hybrid two component system BT4663 in apo and ligand bound forms
Descriptor: 4-deoxy-alpha-L-threo-hex-4-enopyranuronic acid-(1-4)-2-acetamido-2-deoxy-6-O-sulfo-beta-D-glucopyranose, TWO-COMPONENT SYSTEM SENSOR HISTIDINE KINASE/RESPONSE
Authors:Lowe, E.C, Basle, A, Czjzek, M, Firbank, S.J, Bolam, D.N.
Deposit date:2011-09-27
Release date:2012-05-02
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:A Scissor Blade-Like Closing Mechanism Implicated in Transmembrane Signaling in a Bacteroides Hybrid Two-Component System.
Proc.Natl.Acad.Sci.USA, 109, 2012
4A2L
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BU of 4a2l by Molmil
Structure of the periplasmic domain of the heparin and heparan sulphate sensing hybrid two component system BT4663 in apo and ligand bound forms
Descriptor: 1,2-ETHANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, DI(HYDROXYETHYL)ETHER, ...
Authors:Lowe, E.C, Basle, A, Czjzek, M, Firbank, S.J, Bolam, D.N.
Deposit date:2011-09-27
Release date:2012-05-02
Last modified:2014-11-19
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:A Scissor Blade-Like Closing Mechanism Implicated in Transmembrane Signaling in a Bacteroides Hybrid Two-Component System.
Proc.Natl.Acad.Sci.USA, 109, 2012
4AK2
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BU of 4ak2 by Molmil
Structure of BT4661, a SusE-like surface located polysaccharide binding protein from the Bacteroides thetaiotaomicron heparin utilisation locus
Descriptor: 2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose, BT_4661, SODIUM ION
Authors:Lowe, E.C, Basle, A, Czjzek, M, Thomas, S, Murray, H, Firbank, S.J, Bolam, D.N.
Deposit date:2012-02-21
Release date:2013-03-06
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (1.35 Å)
Cite:How members of the human gut microbiota overcome the sulfation problem posed by glycosaminoglycans.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017

217705

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