Author results

4KHP
  • Download 4khp
  • View 4khp
Molmil generated image of 4khp
STRUCTURE OF THE THERMUS THERMOPHILUS 30S RIBOSOMAL SUBUNIT IN COMPLEX WITH DE-6-MSA-PACTAMYCIN
Descriptor:16S Ribosomal RNA, 30S Ribosomal protein S2, 30S Ribosomal protein S3, ...
Authors:Tourigny, D.S., Fernandez, I.S., Kelley, A.C., Ramakrishnan, V.
Deposit date:2013-05-01
Release date:2013-06-05
Last modified:2013-10-30
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Crystal Structure of a Bioactive Pactamycin Analog Bound to the 30S Ribosomal Subunit.
J.Mol.Biol., 425, 2013
4V5J
  • Download 4v5j
  • View 4v5j
Molmil generated image of 4v5j
STRUCTURE OF THE 70S RIBOSOME BOUND TO RELEASE FACTOR 2 AND A SUBSTRATE ANALOG PROVIDES INSIGHTS INTO CATALYSIS OF PEPTIDE RELEASE
Descriptor:16S Ribosomal RNA, 30S RIBOSOMAL PROTEIN S2, 30S RIBOSOMAL PROTEIN S3, ...
Authors:Jin, H., Kelley, A.C., Loakes, D., Ramakrishnan, V.
Deposit date:2010-03-24
Release date:2014-07-09
Last modified:2018-04-18
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Structure of the 70S ribosome bound to release factor 2 and a substrate analog provides insights into catalysis of peptide release.
Proc. Natl. Acad. Sci. U.S.A., 107, 2010
4V5L
  • Download 4v5l
  • View 4v5l
Molmil generated image of 4v5l
THE STRUCTURE OF EF-TU AND AMINOACYL-TRNA BOUND TO THE 70S RIBOSOME WITH A GTP ANALOG
Descriptor:16S RRNA, 30S RIBOSOMAL PROTEIN S2, 30S RIBOSOMAL PROTEIN S3, ...
Authors:Voorhees, R.M., Schmeing, T.M., Ramakrishnan, V.
Deposit date:2010-09-02
Release date:2014-07-09
Last modified:2018-11-21
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:The Mechanism for Activation of GTP Hydrolysis on the Ribosome.
Science, 330, 2010
4V5P
  • Download 4v5p
  • View 4v5p
Molmil generated image of 4v5p
THE CRYSTAL STRUCTURE OF EF-TU AND A9C-TRNA-TRP BOUND TO A NEAR- COGNATE CODON ON THE 70S RIBOSOME
Descriptor:16S RRNA, 30S RIBOSOMAL PROTEIN S2, 30S RIBOSOMAL PROTEIN S3, ...
Authors:Schmeing, T.M., Voorhees, R.M., Ramakrishnan, V.
Deposit date:2010-12-07
Release date:2014-07-09
Last modified:2018-11-21
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:How Mutations in tRNA Distant from the Anticodon Affect the Fidelity of Decoding.
Nat.Struct.Mol.Biol., 18, 2011
4V5Q
  • Download 4v5q
  • View 4v5q
Molmil generated image of 4v5q
THE CRYSTAL STRUCTURE OF EF-TU AND G24A-TRNA-TRP BOUND TO A NEAR- COGNATE CODON ON THE 70S RIBOSOME
Descriptor:16S RRNA, 30S RIBOSOMAL PROTEIN S2, 30S RIBOSOMAL PROTEIN S3, ...
Authors:Schmeing, T.M., Voorhees, R.M., Ramakrishnan, V.
Deposit date:2010-12-07
Release date:2014-07-09
Last modified:2018-11-21
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:How Mutations in tRNA Distant from the Anticodon Affect the Fidelity of Decoding.
Nat.Struct.Mol.Biol., 18, 2011
4V5R
  • Download 4v5r
  • View 4v5r
Molmil generated image of 4v5r
THE CRYSTAL STRUCTURE OF EF-TU AND TRP-TRNA-TRP BOUND TO A COGNATE CODON ON THE 70S RIBOSOME.
Descriptor:16S RRNA, 30S RIBOSOMAL PROTEIN S2, 30S RIBOSOMAL PROTEIN S3, ...
Authors:Schmeing, T.M., Voorhees, R.M., Ramakrishnan, V.
Deposit date:2010-12-07
Release date:2014-07-09
Last modified:2018-11-21
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:How Mutations in tRNA Distant from the Anticodon Affect the Fidelity of Decoding.
Nat.Struct.Mol.Biol., 18, 2011
4V5S
  • Download 4v5s
  • View 4v5s
Molmil generated image of 4v5s
THE CRYSTAL STRUCTURE OF EF-TU AND G24A-TRNA-TRP BOUND TO A COGNATE CODON ON THE 70S RIBOSOME.
Descriptor:16S RRNA, 30S RIBOSOMAL PROTEIN S2, 30S RIBOSOMAL PROTEIN S3, ...
Authors:Schmeing, T.M., Voorhees, R.M., Ramakrishnan, V.
Deposit date:2010-12-07
Release date:2014-07-09
Last modified:2018-11-21
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:How Mutations in tRNA Distant from the Anticodon Affect the Fidelity of Decoding.
Nat.Struct.Mol.Biol., 18, 2011
4V8N
  • Download 4v8n
  • View 4v8n
Molmil generated image of 4v8n
THE CRYSTAL STRUCTURE OF AGMATIDINE TRNA-ILE2 BOUND TO THE 70S RIBOSOME IN THE A AND P SITE.
Descriptor:16S RRNA, 30S RIBOSOMAL PROTEIN S2, 30S RIBOSOMAL PROTEIN S3, ...
Authors:Voorhees, R.M., Mandal, D., Neubauer, C., Koehrer, C., RajBhandary, U.L., Ramakrishnan, V.
Deposit date:2013-02-13
Release date:2014-07-09
Last modified:2014-12-10
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:The Structural Basis for Specific Decoding of Aua by Isoleucine tRNA on the Ribosome
Nat.Struct.Mol.Biol., 20, 2013
4V8Q
  • Download 4v8q
  • View 4v8q
Molmil generated image of 4v8q
COMPLEX OF SMPB, A TMRNA FRAGMENT AND EF-TU-GDP-KIRROMYCIN WITH THE 70S RIBOSOME
Descriptor:50S RIBOSOMAL PROTEIN L27, 50S RIBOSOMAL PROTEIN L28, 50S RIBOSOMAL PROTEIN L29, ...
Authors:Neubauer, C., Gillet, R., Kelley, A.C., Ramakrishnan, V.
Deposit date:2011-12-10
Release date:2014-07-09
Last modified:2018-03-07
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Decoding in the absence of a codon by tmRNA and SmpB in the ribosome.
Science, 335, 2012
5MDZ
  • Download 5mdz
  • View 5mdz
Molmil generated image of 5mdz
STRUCTURE OF THE 70S RIBOSOME (EMPTY A SITE)
Descriptor:23S ribosomal RNA, 16S ribosomal RNA, 5S ribosomal RNA, ...
Authors:James, N.R., Brown, A., Gordiyenko, Y., Ramakrishnan, V.
Deposit date:2016-11-13
Release date:2016-12-14
Last modified:2018-10-03
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Translational termination without a stop codon.
Science, 354, 2016
1IBL
  • Download 1ibl
  • View 1ibl
Molmil generated image of 1ibl
STRUCTURE OF THE THERMUS THERMOPHILUS 30S RIBOSOMAL SUBUNIT IN COMPLEX WITH A MESSENGER RNA FRAGMENT AND COGNATE TRANSFER RNA ANTICODON STEM-LOOP BOUND AT THE A SITE AND WITH THE ANTIBIOTIC PAROMOMYCIN
Descriptor:16S RIBOSOMAL RNA, P-SITE MESSENGER RNA FRAGMENT, ANTICODON STEM-LOOP OF PHENYLALANINE TRANSFER RNA, ...
Authors:Ogle, J.M., Brodersen, D.E., Clemons Jr., W.M., Tarry, M.J., Carter, A.P., Ramakrishnan, V.
Deposit date:2001-03-28
Release date:2001-05-04
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.11 Å)
Cite:Recognition of cognate transfer RNA by the 30S ribosomal subunit.
Science, 292, 2001
4B3S
  • Download 4b3s
  • View 4b3s
Molmil generated image of 4b3s
CRYSTAL STRUCTURE OF THE 30S RIBOSOME IN COMPLEX WITH COMPOUND 37
Descriptor:16S RIBOSOMAL RNA, 30S RIBOSOMAL PROTEIN S2, 30S RIBOSOMAL PROTEIN S3, ...
Authors:Ng, C.L., Lang, K., Shcherbakov, D., Matt, T., Perez-Fernandez, D., Patak, R., Meyer, M., Duscha, S., Akbergenov, R., Boukari, H., Freihofer, P., Kudyba, I., Reddy, M.S.K., Nandurikar, R.S., Ramakrishnan, V., Vasella, A., Bottger, E.C.
Deposit date:2012-07-26
Release date:2013-08-07
Last modified:2019-03-06
Method:X-RAY DIFFRACTION (3.15 Å)
Cite:4'-O-Substitutions Determine Selectivity of Aminoglycoside Antibiotics
Nat.Commun., 5, 2014
4JV5
  • Download 4jv5
  • View 4jv5
Molmil generated image of 4jv5
CRYSTAL STRUCTURES OF PSEUDOURIDINILATED STOP CODONS WITH ASLS
Descriptor:16S ribosomal RNA, 30S ribosomal protein S2, 30S ribosomal protein S3, ...
Authors:Fernandez, I.S., Ng, C.L., Kelley, A.C., Guowei, W., Yu, Y.T., Ramakrishnan, V.
Deposit date:2013-03-25
Release date:2013-06-26
Last modified:2013-08-21
Method:X-RAY DIFFRACTION (3.162 Å)
Cite:Unusual base pairing during the decoding of a stop codon by the ribosome.
Nature, 500, 2013
1HR0
  • Download 1hr0
  • View 1hr0
Molmil generated image of 1hr0
CRYSTAL STRUCTURE OF INITIATION FACTOR IF1 BOUND TO THE 30S RIBOSOMAL SUBUNIT
Descriptor:16S RIBOSOMAL RNA, FRAGMENT OF MESSENGER RNA, 30S RIBOSOMAL PROTEIN S2, ...
Authors:Carter, A.P., Clemons Jr., W.M., Brodersen, D.E., Morgan-Warren, R.J., Wimberly, B.T., Ramakrishnan, V.
Deposit date:2000-12-20
Release date:2001-01-24
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Crystal structure of an initiation factor bound to the 30S ribosomal subunit.
Science, 291, 2001
2UXD
  • Download 2uxd
  • View 2uxd
Molmil generated image of 2uxd
CRYSTAL STRUCTURE OF AN EXTENDED TRNA ANTICODON STEM LOOP IN COMPLEX WITH ITS COGNATE MRNA CGGG IN THE CONTEXT OF THE THERMUS THERMOPHILUS 30S SUBUNIT.
Descriptor:16S RIBOSOMAL RNA, RIBOSOMAL PROTEIN S2, RIBOSOMAL PROTEIN S3, ...
Authors:Dunham, C.M., Selmer, M., Phelps, S.S., Kelley, A.C., Suzuki, T., Joseph, S., Ramakrishnan, V.
Deposit date:2007-03-28
Release date:2007-10-02
Last modified:2019-03-06
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Structures of Trnas with an Expanded Anticodon Loop in the Decoding Center of the 30S Ribosomal Subunit.
RNA, 13, 2007
3J6B
  • Download 3j6b
  • View 3j6b
Molmil generated image of 3j6b
STRUCTURE OF THE YEAST MITOCHONDRIAL LARGE RIBOSOMAL SUBUNIT
Descriptor:21S ribosomal RNA, 54S ribosomal protein RML2, mitochondrial, ...
Authors:Amunts, A., Brown, A., Bai, X.C., Llacer, J.L., Hussain, T., Emsley, P., Long, F., Murshudov, G., Scheres, S.H.W., Ramakrishnan, V.
Deposit date:2014-01-22
Release date:2014-04-09
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Structure of the yeast mitochondrial large ribosomal subunit.
Science, 343, 2014
4V5K
  • Download 4v5k
  • View 4v5k
Molmil generated image of 4v5k
STRUCTURE OF CYTOTOXIC DOMAIN OF COLICIN E3 BOUND TO THE 70S RIBOSOME
Descriptor:16S ribosomal RNA, 30S RIBOSOMAL PROTEIN S2, 30S RIBOSOMAL PROTEIN S3, ...
Authors:Ng, C.L., Lang, K., Meenan, N.A.G., Sharma, A., Kelley, A.C., Kleanthous, C., Ramakrishnan, V.
Deposit date:2010-05-29
Release date:2014-07-09
Last modified:2018-03-07
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Structural Basis for 16S Ribosomal RNA Cleavage by the Cytotoxic Domain of Colicin E3.
Nat.Struct.Mol.Biol., 17, 2010
1XMO
  • Download 1xmo
  • View 1xmo
Molmil generated image of 1xmo
CRYSTAL STRUCTURE OF MNM5U34T6A37-TRNALYSUUU COMPLEXED WITH AAG-MRNA IN THE DECODING CENTER
Descriptor:16S ribosomal RNA, A-Site Messenger RNA, Anticodon Transfer RNA, ...
Authors:Murphy, F.V., Ramakrishnan, V., Malkiewicz, A., Agris, P.F.
Deposit date:2004-10-04
Release date:2004-12-14
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.25 Å)
Cite:The role of modifications in codon discrimination by tRNA(Lys)(UUU).
Nat.Struct.Mol.Biol., 11, 2004
5MRC
  • Download 5mrc
  • View 5mrc
Molmil generated image of 5mrc
STRUCTURE OF THE YEAST MITOCHONDRIAL RIBOSOME - CLASS A
Descriptor:21S ribosomal RNA, uL2m, uL3m, ...
Authors:Desai, N., Brown, A., Amunts, A., Ramakrishnan, V.
Deposit date:2016-12-22
Release date:2017-02-15
Last modified:2018-02-07
Method:ELECTRON MICROSCOPY (3.25 Å)
Cite:The structure of the yeast mitochondrial ribosome.
Science, 355, 2017
1FKA
  • Download 1fka
  • View 1fka
Molmil generated image of 1fka
STRUCTURE OF FUNCTIONALLY ACTIVATED SMALL RIBOSOMAL SUBUNIT AT 3.3 A RESOLUTION
Descriptor:16S RIBOSOMAL RNA, 30S RIBOSOMAL PROTEIN S2, 30S RIBOSOMAL PROTEIN S3, ...
Authors:Schluenzen, F., Tocilj, A., Zarivach, R., Harms, J., Gluehmann, M., Janell, D., Bashan, A., Bartels, H., Agmon, I., Franceschi, F., Yonath, A.
Deposit date:2000-08-09
Release date:2000-09-04
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Structure of functionally activated small ribosomal subunit at 3.3 angstroms resolution.
Cell(Cambridge,Mass.), 102, 2000
1HNZ
  • Download 1hnz
  • View 1hnz
Molmil generated image of 1hnz
STRUCTURE OF THE THERMUS THERMOPHILUS 30S RIBOSOMAL SUBUNIT IN COMPLEX WITH HYGROMYCIN B
Descriptor:16S RIBOSOMAL RNA, FRAGMENT OF MESSENGER RNA, 30S RIBOSOMAL PROTEIN S2, ...
Authors:Brodersen, D.E., Clemons Jr., W.M., Carter, A.P., Morgan-Warren, R., Wimberly, B.T., Ramakrishnan, V.
Deposit date:2000-12-08
Release date:2001-02-21
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:The structural basis for the action of the antibiotics tetracycline, pactamycin, and hygromycin B on the 30S ribosomal subunit.
Cell(Cambridge,Mass.), 103, 2000
4V5C
  • Download 4v5c
  • View 4v5c
Molmil generated image of 4v5c
STRUCTURE OF THE THERMUS THERMOPHILUS 70S RIBOSOME IN COMPLEX WITH MRNA, PAROMOMYCIN, ACYLATED A-SITE TRNA, DEACYLATED P-SITE TRNA, AND E-SITE TRNA.
Descriptor:16S ribosomal RNA, 30S RIBOSOMAL PROTEIN S2, 30S RIBOSOMAL PROTEIN S3, ...
Authors:Voorhees, R.M., Weixlbaumer, A., Loakes, D., Kelley, A.C., Ramakrishnan, V.
Deposit date:2009-03-24
Release date:2014-07-09
Last modified:2018-04-18
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Insights Into Substrate Stabilization from Snapshots of the Peptidyl Transferase Center of the Intact 70S Ribosome
Nat.Struct.Mol.Biol., 16, 2009
4V7J
  • Download 4v7j
  • View 4v7j
Molmil generated image of 4v7j
STRUCTURE OF RELE NUCLEASE BOUND TO THE 70S RIBOSOME (PRECLEAVAGE STATE)
Descriptor:30S ribosomal protein S2, 30S ribosomal protein S3, 30S ribosomal protein S4, ...
Authors:Neubauer, C., Gao, Y.-G., Andersen, K.R., Dunham, C.M., Kelley, A.C., Hentschel, J., Gerdes, K., Ramakrishnan, V., Brodersen, D.E.
Deposit date:2009-11-02
Release date:2014-07-09
Last modified:2014-12-10
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:The structural basis for mRNA recognition and cleavage by the ribosome-dependent endonuclease RelE.
Cell(Cambridge,Mass.), 139, 2009
4V9I
  • Download 4v9i
  • View 4v9i
Molmil generated image of 4v9i
CRYSTAL STRUCTURE OF THERMUS THERMOPHILUS 70S IN COMPLEX WITH TRNAS AND MRNA CONTAINING A PSEUDOURIDINE IN A STOP CODON
Descriptor:16S ribosomal RNA, 30S Ribosomal protein S2, 30S Ribosomal protein S3, ...
Authors:Fernandez, I.S., Ng, C.L., Kelley, A.C., Guowei, W., Yu, Y.T., Ramakrishnan, V.
Deposit date:2013-04-04
Release date:2014-07-09
Last modified:2014-12-10
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Unusual base pairing during the decoding of a stop codon by the ribosome.
Nature, 500, 2013
1IBK
  • Download 1ibk
  • View 1ibk
Molmil generated image of 1ibk
STRUCTURE OF THE THERMUS THERMOPHILUS 30S RIBOSOMAL SUBUNIT IN COMPLEX WITH THE ANTIBIOTIC PAROMOMYCIN
Descriptor:16S RIBOSOMAL RNA, P-SITE MESSENGER RNA FRAGMENT, 30S RIBOSOMAL PROTEIN S2, ...
Authors:Ogle, J.M., Brodersen, D.E., Clemons Jr., W.M., Tarry, M.J., Carter, A.P., Ramakrishnan, V.
Deposit date:2001-03-28
Release date:2001-05-04
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.31 Å)
Cite:Recognition of cognate transfer RNA by the 30S ribosomal subunit.
Science, 292, 2001