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1EFE
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BU of 1efe by Molmil
AN ACTIVE MINI-PROINSULIN, M2PI
Descriptor: MINI-PROINSULIN
Authors:Cho, Y, Chang, S.G, Choi, K.D, Shin, H, Ahn, B, Kim, K.S.
Deposit date:2000-02-08
Release date:2000-03-17
Last modified:2022-02-16
Method:SOLUTION NMR
Cite:Solution Structure of an Active Mini-Proinsulin, M2PI: Inter-chain Flexibility is Crucial for Insulin Activity
J.Biochem.Mol.Biol., 33, 2000
2OS5
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BU of 2os5 by Molmil
Macrophage migration inhibitory factor from Ancylostoma ceylanicum
Descriptor: AceMIF, SULFATE ION
Authors:Cho, Y, Lolis, E.
Deposit date:2007-02-05
Release date:2007-06-12
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structural and functional characterization of a secreted hookworm Macrophage Migration Inhibitory Factor (MIF) that interacts with the human MIF receptor CD74.
J.Biol.Chem., 282, 2007
1TSR
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BU of 1tsr by Molmil
P53 CORE DOMAIN IN COMPLEX WITH DNA
Descriptor: DNA (5'-D(*AP*TP*AP*AP*TP*TP*GP*GP*GP*CP*AP*AP*GP*TP*CP*TP*A P*GP*GP*AP*A)-3'), DNA (5'-D(*TP*TP*TP*CP*CP*TP*AP*GP*AP*CP*TP*TP*GP*CP*CP*CP*A P*AP*TP*TP*A)-3'), PROTEIN (P53 TUMOR SUPPRESSOR), ...
Authors:Cho, Y, Gorina, S, Jeffrey, P, Pavletich, N.
Deposit date:1995-07-28
Release date:1996-01-29
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structure of a p53 tumor suppressor-DNA complex: understanding tumorigenic mutations.
Science, 265, 1994
1TUP
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BU of 1tup by Molmil
TUMOR SUPPRESSOR P53 COMPLEXED WITH DNA
Descriptor: DNA (5'-D(*AP*TP*AP*AP*TP*TP*GP*GP*GP*CP*AP*AP*GP*TP*CP*TP*A P*GP*GP*AP*A)-3'), DNA (5'-D(*TP*TP*TP*CP*CP*TP*AP*GP*AP*CP*TP*TP*GP*CP*CP*CP*A P*AP*TP*TP*A)-3'), PROTEIN (P53 TUMOR SUPPRESSOR ), ...
Authors:Cho, Y, Gorina, S, Jeffrey, P.D, Pavletich, N.P.
Deposit date:1995-07-11
Release date:1995-07-11
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structure of a p53 tumor suppressor-DNA complex: understanding tumorigenic mutations.
Science, 265, 1994
1NH7
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BU of 1nh7 by Molmil
ATP PHOSPHORIBOSYLTRANSFERASE (ATP-PRTASE) FROM MYCOBACTERIUM TUBERCULOSIS
Descriptor: ATP Phosphoribosyltransferase, MAGNESIUM ION, SULFATE ION
Authors:Cho, Y, Sharma, V, Sacchettini, J.C, TB Structural Genomics Consortium (TBSGC)
Deposit date:2002-12-18
Release date:2003-02-11
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Crystal Structure of ATP Phosphoribosyltransferase from Mycobacterium Tuberculosis
J.Biol.Chem., 278, 2003
1NH8
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BU of 1nh8 by Molmil
ATP PHOSPHORIBOSYLTRANSFERASE (ATP-PRTASE) FROM MYCOBACTERIUM TUBERCULOSIS IN COMPLEX WITH AMP AND HISTIDINE
Descriptor: ADENOSINE MONOPHOSPHATE, ATP Phosphoribosyltransferase, HISTIDINE, ...
Authors:Cho, Y, Sharma, V, Sacchettini, J.C, TB Structural Genomics Consortium (TBSGC)
Deposit date:2002-12-18
Release date:2003-02-11
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal structure of ATP phosphoribosyltransferase from Mycobacterium tuberculosis
J.Biol.Chem., 278, 2003
3RF4
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BU of 3rf4 by Molmil
Ancylostoma ceylanicum mif in complex with furosemide
Descriptor: 5-(AMINOSULFONYL)-4-CHLORO-2-[(2-FURYLMETHYL)AMINO]BENZOIC ACID, ACETATE ION, IMIDAZOLE, ...
Authors:Cho, Y, Lolis, E.
Deposit date:2011-04-05
Release date:2011-10-12
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Drug Repositioning and Pharmacophore Identification in the Discovery of Hookworm MIF Inhibitors.
Chem.Biol., 18, 2011
3RF5
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BU of 3rf5 by Molmil
Ancylostoma ceylanicum mif in complex with n-(2,3,4,5,6-pentafluoro-benzyl)-4-sulfamoyl-benzamide
Descriptor: 2-[(furan-2-ylmethyl)amino]benzoic acid, ACETATE ION, IMIDAZOLE, ...
Authors:Cho, Y, Lolis, E.
Deposit date:2011-04-05
Release date:2011-10-12
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Drug Repositioning and Pharmacophore Identification in the Discovery of Hookworm MIF Inhibitors.
Chem.Biol., 18, 2011
2E6L
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BU of 2e6l by Molmil
structure of mouse WRN exonuclease domain
Descriptor: SULFATE ION, Werner syndrome ATP-dependent helicase homolog, ZINC ION
Authors:Cho, Y, Choi, J.M.
Deposit date:2006-12-27
Release date:2007-01-16
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:probing the roles of active site residues in 3'-5' exonuclease of werner syndrome protein
TO BE PUBLISHED
2E6M
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BU of 2e6m by Molmil
structure of mouse werner exonuclease domain
Descriptor: SULFATE ION, Werner syndrome ATP-dependent helicase homolog
Authors:Cho, Y, Choi, J.M.
Deposit date:2006-12-27
Release date:2007-01-16
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2 Å)
Cite:probing the roles of active site residues in 3'-5' exonuclease of werner syndrome protein
TO BE PUBLISHED
4WFQ
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BU of 4wfq by Molmil
Crystal structure of TFIIH subunit
Descriptor: GLYCEROL, SULFATE ION, Suppressor of stem-loop protein 1
Authors:Cho, Y, Kim, J.S, Lim, H.S.
Deposit date:2014-09-17
Release date:2015-02-18
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal structure of the Rad3/XPD regulatory domain of Ssl1/p44
J.Biol.Chem., 290, 2015
4R89
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BU of 4r89 by Molmil
Crystal structure of paFAN1 - 5' flap DNA complex with Manganase
Descriptor: DNA (5'-D(P*AP*CP*CP*AP*GP*AP*CP*AP*CP*AP*CP*AP*TP*TP*C)-3'), DNA (5'-D(P*GP*AP*AP*TP*GP*TP*GP*TP*GP*TP*CP*TP*CP*AP*AP*TP*CP*CP*CP*AP*AP*C)-3'), DNA (5'-D(P*GP*TP*TP*GP*GP*GP*AP*TP*TP*G)-3'), ...
Authors:Cho, Y, Gwon, G.H, Kim, Y.R.
Deposit date:2014-08-30
Release date:2014-10-29
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (4.002 Å)
Cite:Crystal structure of a Fanconi anemia-associated nuclease homolog bound to 5' flap DNA: basis of interstrand cross-link repair by FAN1
Genes Dev., 28, 2014
4R8A
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BU of 4r8a by Molmil
Crystal structure of paFAN1 - 5' flap DNA complex
Descriptor: DNA (5'-D(P*AP*CP*CP*AP*GP*AP*CP*AP*CP*AP*CP*AP*TP*TP*C)-3'), DNA (5'-D(P*GP*AP*AP*TP*GP*TP*GP*TP*GP*TP*CP*TP*CP*AP*AP*TP*CP*CP*CP*AP*A)-3'), DNA (5'-D(P*GP*TP*TP*GP*GP*GP*AP*TP*TP*G)-3'), ...
Authors:Cho, Y, Gwon, G.H, Kim, Y.R.
Deposit date:2014-08-30
Release date:2014-10-29
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Crystal structure of a Fanconi anemia-associated nuclease homolog bound to 5' flap DNA: basis of interstrand cross-link repair by FAN1
Genes Dev., 28, 2014
2ZXX
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BU of 2zxx by Molmil
Crystal structure of Cdt1/geminin complex
Descriptor: DNA replication factor Cdt1, Geminin
Authors:Cho, Y, Lee, C, Hong, B.S, Choi, J.M.
Deposit date:2009-01-08
Release date:2009-02-17
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural basis for inhibition of the replication licensing factor Cdt1 by geminin
Nature, 430, 2004
2ZU6
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BU of 2zu6 by Molmil
crystal structure of the eIF4A-PDCD4 complex
Descriptor: 1,2-ETHANEDIOL, ACETIC ACID, Eukaryotic initiation factor 4A-I, ...
Authors:Cho, Y, Chang, J.H, Sohn, S.Y.
Deposit date:2008-10-13
Release date:2009-02-24
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal structure of the eIF4A-PDCD4 complex
Proc.Natl.Acad.Sci.Usa, 106, 2009
3IJJ
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BU of 3ijj by Molmil
Ternary Complex of Macrophage Migration Inhibitory Factor (MIF) Bound Both to 4-hydroxyphenylpyruvate and to the Allosteric Inhibitor AV1013 (R-stereoisomer)
Descriptor: (2E)-2-hydroxy-3-(4-hydroxyphenyl)prop-2-enoic acid, (2R)-2-amino-1-[2-(1-methylethyl)pyrazolo[1,5-a]pyridin-3-yl]propan-1-one, 3-(4-HYDROXY-PHENYL)PYRUVIC ACID, ...
Authors:Crichlow, G.V, Cho, Y, Lolis, E.J.
Deposit date:2009-08-04
Release date:2010-06-16
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.25 Å)
Cite:Allosteric inhibition of macrophage migration inhibitory factor revealed by ibudilast.
Proc.Natl.Acad.Sci.USA, 107, 2010
3IJG
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BU of 3ijg by Molmil
Macrophage Migration Inhibitory Factor (MIF) Bound to the (R)-Stereoisomer of AV1013
Descriptor: (2R)-2-amino-1-[2-(1-methylethyl)pyrazolo[1,5-a]pyridin-3-yl]propan-1-one, CHLORIDE ION, Macrophage migration inhibitory factor
Authors:Crichlow, G.V, Cho, Y, Lolis, E.J.
Deposit date:2009-08-04
Release date:2010-06-16
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Allosteric inhibition of macrophage migration inhibitory factor revealed by ibudilast.
Proc.Natl.Acad.Sci.USA, 107, 2010
7F4U
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BU of 7f4u by Molmil
Cryo-EM structure of TELO2-TTI1-TTI2 complex
Descriptor: TELO2-interacting protein 1 homolog, TELO2-interacting protein 2, Telomere length regulation protein TEL2 homolog
Authors:Cho, Y, Kim, Y.
Deposit date:2021-06-21
Release date:2022-06-22
Method:ELECTRON MICROSCOPY (4.2 Å)
Cite:Structure of the Human TELO2-TTI1-TTI2 Complex.
J.Mol.Biol., 434, 2022
3A4C
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BU of 3a4c by Molmil
Crystal structure of cdt1 C terminal domain
Descriptor: DNA replication factor Cdt1
Authors:Cho, Y, Lee, J.H.
Deposit date:2009-07-06
Release date:2009-10-13
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.889 Å)
Cite:Structure of the Cdt1 C-terminal domain: Conservation of the winged helix fold in replication licensing factors
Protein Sci., 18, 2009
3B6T
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BU of 3b6t by Molmil
Crystal Structure of the GLUR2 Ligand Binding Core (S1S2J) T686A Mutant in Complex with Quisqualate at 2.1 Resolution
Descriptor: (S)-2-AMINO-3-(3,5-DIOXO-[1,2,4]OXADIAZOLIDIN-2-YL)-PROPIONIC ACID, Glutamate receptor 2, SULFATE ION
Authors:Cho, Y, Lolis, E, Howe, J.R.
Deposit date:2007-10-29
Release date:2008-02-05
Last modified:2021-10-20
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural and single-channel results indicate that the rates of ligand binding domain closing and opening directly impact AMPA receptor gating.
J.Neurosci., 28, 2008
3B6Q
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BU of 3b6q by Molmil
Crystal Structure of the GLUR2 Ligand Binding Core (S1S2J) Mutant T686A in Complex with Glutamate at 2.0 Resolution
Descriptor: GLUTAMIC ACID, Glutamate receptor 2, SULFATE ION
Authors:Cho, Y, Lolis, E, Howe, J.R.
Deposit date:2007-10-29
Release date:2008-02-05
Last modified:2021-10-20
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural and single-channel results indicate that the rates of ligand binding domain closing and opening directly impact AMPA receptor gating.
J.Neurosci., 28, 2008
3B6W
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BU of 3b6w by Molmil
Crystal Structure of the GLUR2 Ligand Binding Core (S1S2J) T686S Mutant in Complex with Glutamate at 1.7 Resolution
Descriptor: GLUTAMIC ACID, Glutamate receptor 2, SULFATE ION
Authors:Cho, Y, Lolis, E, Howe, J.R.
Deposit date:2007-10-29
Release date:2008-02-05
Last modified:2021-10-20
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structural and single-channel results indicate that the rates of ligand binding domain closing and opening directly impact AMPA receptor gating.
J.Neurosci., 28, 2008
2YT4
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BU of 2yt4 by Molmil
Crystal structure of human DGCR8 core
Descriptor: Protein DGCR8
Authors:Cho, Y, Sohn, S.Y.
Deposit date:2007-04-05
Release date:2007-08-21
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal structure of human DGCR8 core
Nat.Struct.Mol.Biol., 14, 2007
6LDK
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BU of 6ldk by Molmil
Isoleucyl-tRNA synthetase from Candida albicans complexed with a isoleucyl-adenylate
Descriptor: ADENOSINE MONOPHOSPHATE, ISOLEUCINE, Isoleucine--tRNA ligase
Authors:Cho, Y, Chung, S.
Deposit date:2019-11-21
Release date:2020-11-04
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structural Basis for the Antibiotic Resistance of Eukaryotic Isoleucyl-tRNA Synthetase.
Mol.Cells, 43, 2020
7DG2
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BU of 7dg2 by Molmil
Nse1-Nse3-Nse4 complex
Descriptor: ACETATE ION, GLYCEROL, MAGE domain-containing protein, ...
Authors:Cho, Y, Jo, A.
Deposit date:2020-11-10
Release date:2021-05-26
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structure Basis for Shaping the Nse4 Protein by the Nse1 and Nse3 Dimer within the Smc5/6 Complex.
J.Mol.Biol., 433, 2021

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