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5J3Q
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BU of 5j3q by Molmil
Crystal structure of S. pombe Dcp1:Edc1 mRNA decapping complex
Descriptor: Edc1, mRNA-decapping enzyme subunit 1
Authors:Valkov, E, Muthukumar, S, Chang, C.T, Jonas, S, Weichenrieder, O, Izaurralde, E.
Deposit date:2016-03-31
Release date:2016-05-18
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.87 Å)
Cite:Structure of the Dcp2-Dcp1 mRNA-decapping complex in the activated conformation.
Nat.Struct.Mol.Biol., 23, 2016
5J3T
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BU of 5j3t by Molmil
Crystal structure of S. pombe Dcp2:Dcp1:Edc1 mRNA decapping complex
Descriptor: Edc1, FORMIC ACID, MAGNESIUM ION, ...
Authors:Valkov, E, Muthukumar, S, Chang, C.T, Jonas, S, Weichenrieder, O, Izaurralde, E.
Deposit date:2016-03-31
Release date:2016-05-18
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structure of the Dcp2-Dcp1 mRNA-decapping complex in the activated conformation.
Nat.Struct.Mol.Biol., 23, 2016
5J3Y
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BU of 5j3y by Molmil
Crystal structure of S. pombe Dcp2:Dcp1 mRNA decapping complex
Descriptor: mRNA decapping complex subunit 2, mRNA-decapping enzyme subunit 1
Authors:Valkov, E, Muthukumar, S, Chang, C.T, Jonas, S, Weichenrieder, O, Izaurralde, E.
Deposit date:2016-03-31
Release date:2016-05-18
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (3.288 Å)
Cite:Structure of the Dcp2-Dcp1 mRNA-decapping complex in the activated conformation.
Nat.Struct.Mol.Biol., 23, 2016
2Y92
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BU of 2y92 by Molmil
Crystal structure of MAL adaptor protein
Descriptor: 2,3-DIHYDROXY-1,4-DITHIOBUTANE, TOLL/INTERLEUKIN-1 RECEPTOR DOMAIN-CONTAINING ADAPTER PROTEIN,
Authors:Valkov, E, Stamp, A, Martin, J.L, Kobe, B.
Deposit date:2011-02-11
Release date:2011-09-14
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (3.01 Å)
Cite:Crystal Structure of Toll-Like Receptor Adaptor Mal/Tirap Reveals the Molecular Basis for Signal Transduction and Disease Protection.
Proc.Natl.Acad.Sci.USA, 108, 2011
3DLR
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BU of 3dlr by Molmil
Crystal structure of the catalytic core domain from PFV integrase
Descriptor: Integrase, MAGNESIUM ION
Authors:Valkov, E, Cherepanov, P.
Deposit date:2008-06-29
Release date:2008-12-09
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Functional and structural characterization of the integrase from the prototype foamy virus.
Nucleic Acids Res., 37, 2009
6FNY
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BU of 6fny by Molmil
CRYSTAL STRUCTURE OF A CHOLINE SULFATASE FROM SINORHIZOBIUM MELLILOTI
Descriptor: CALCIUM ION, Choline-sulfatase
Authors:Valkov, E, Van Loo, B, Hollfelder, F, Hyvonen, M.
Deposit date:2018-02-05
Release date:2018-02-28
Last modified:2018-04-04
Method:X-RAY DIFFRACTION (2.79 Å)
Cite:Structural and Mechanistic Analysis of the Choline Sulfatase from Sinorhizobium melliloti: A Class I Sulfatase Specific for an Alkyl Sulfate Ester.
J. Mol. Biol., 430, 2018
5C5W
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BU of 5c5w by Molmil
1.25 A resolution structure of an RNA 20-mer
Descriptor: RNA (5'-R(P*CP*CP*UP*GP*AP*GP*UP*UP*CP*AP*AP*UP*UP*CP*UP*AP*GP*CP*G)-3')
Authors:Stewart, M, Valkov, E.
Deposit date:2015-06-22
Release date:2015-10-14
Last modified:2017-09-13
Method:X-RAY DIFFRACTION (1.25 Å)
Cite:1.25 angstrom resolution structure of an RNA 20-mer that binds to the TREX2 complex.
Acta Crystallogr.,Sect.F, 71, 2015
4WPX
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BU of 4wpx by Molmil
Chaetomium theromophilum TREX2 CID domain complex
Descriptor: Cell division control protein 31-like protein, Putative SAC3 family protein, Putative uncharacterized protein
Authors:Valkov, E, Stewart, M.
Deposit date:2014-10-21
Release date:2015-06-17
Last modified:2015-07-15
Method:X-RAY DIFFRACTION (3.31 Å)
Cite:Structural Characterization of the Chaetomium thermophilum TREX-2 Complex and its Interaction with the mRNA Nuclear Export Factor Mex67:Mtr2.
Structure, 23, 2015
4UPK
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BU of 4upk by Molmil
Phosphonate monoester hydrolase SpPMH from Silicibacter pomeroyi
Descriptor: PHOSPHONATE MONOESTER HYDROLASE
Authors:Valkov, E, van Loo, B, Hollfelder, F, Hyvonen, M.
Deposit date:2014-06-17
Release date:2015-07-01
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.24 Å)
Cite:Balancing Specificity and Promiscuity in Enzyme Evolution: Multidimensional Activity Transitions in the Alkaline Phosphatase Superfamily.
J.Am.Chem.Soc., 141, 2019
4AF0
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BU of 4af0 by Molmil
Crystal structure of cryptococcal inosine monophosphate dehydrogenase
Descriptor: INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE, INOSINIC ACID, MYCOPHENOLIC ACID, ...
Authors:Valkov, E, Stamp, A, Morrow, C.A, Kobe, B, Fraser, J.A.
Deposit date:2012-01-15
Release date:2012-10-24
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:De Novo GTP Biosynthesis is Critical for Virulence of the Fungal Pathogen Cryptococcus Neoformans
Plos Pathog., 8, 2012
4WPM
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BU of 4wpm by Molmil
Structure of the Chaetomium thermophilum Mex67:Mtr2 Complex
Descriptor: SULFATE ION, mRNA export protein
Authors:Aibara, S, Valkov, E, Stewart, M.
Deposit date:2014-10-20
Release date:2015-07-15
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural characterization of the principal mRNA-export factor Mex67-Mtr2 from Chaetomium thermophilum.
Acta Crystallogr.,Sect.F, 71, 2015
4WP6
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BU of 4wp6 by Molmil
Structure of the Mex67 LRR domain from Chaetomium thermophilum
Descriptor: mRNA export protein
Authors:Aibara, S, Valkov, E, Lamers, M, Stewart, M.
Deposit date:2014-10-17
Release date:2015-07-15
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structural characterization of the principal mRNA-export factor Mex67-Mtr2 from Chaetomium thermophilum.
Acta Crystallogr.,Sect.F, 71, 2015
6H3Z
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BU of 6h3z by Molmil
Crystal structure of a C-terminal MIF4G domain in NOT1
Descriptor: CCR4-not transcription complex subunit 1, SODIUM ION
Authors:Raisch, T, Sandmeir, F, Weichenrieder, O, Valkov, E, Izaurralde, E.
Deposit date:2018-07-19
Release date:2018-11-07
Last modified:2018-12-26
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structural and biochemical analysis of a NOT1 MIF4G-like domain of the CCR4-NOT complex.
J. Struct. Biol., 204, 2018
8FY3
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BU of 8fy3 by Molmil
Structure of NOT1:NOT10:NOT11 module of the human CCR4-NOT complex
Descriptor: CCR4-NOT transcription complex subunit 1, CCR4-NOT transcription complex subunit 10, CCR4-NOT transcription complex subunit 11
Authors:Lea, S.M, Deme, J.C, Raisch, T, Pekovic, F, Valkov, E.
Deposit date:2023-01-25
Release date:2023-07-26
Last modified:2023-08-02
Method:ELECTRON MICROSCOPY (2.88 Å)
Cite:Structure and assembly of the NOT10:11 module of the CCR4-NOT complex.
Commun Biol, 6, 2023
8FY4
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BU of 8fy4 by Molmil
Structure of NOT1:NOT10:NOT11 module of the chicken CCR4-NOT complex
Descriptor: CCR4-NOT transcription complex subunit 1, CCR4-NOT transcription complex subunit 10, CCR4-NOT transcription complex subunit 11
Authors:Lea, S.M, Deme, J.C, Raisch, T, Levdansky, Y, Valkov, E.
Deposit date:2023-01-25
Release date:2023-08-30
Method:ELECTRON MICROSCOPY (2.57 Å)
Cite:Structure and assembly of the NOT10:11 module of the CCR4-NOT complex.
Commun Biol, 6, 2023
5T47
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BU of 5t47 by Molmil
Crystal structure of the D. melanogaster eIF4E-eIF4G complex
Descriptor: Eukaryotic translation initiation factor 4E, Eukaryotic translation initiation factor 4G, isoform A, ...
Authors:Gruener, S, Peter, D, Weber, R, Wohlbold, L, Chung, M.-Y, Weichenrieder, O, Valkov, E, Igreja, C, Izaurralde, E.
Deposit date:2016-08-29
Release date:2016-10-26
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:The Structures of eIF4E-eIF4G Complexes Reveal an Extended Interface to Regulate Translation Initiation.
Mol.Cell, 64, 2016
5T46
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BU of 5t46 by Molmil
Crystal structure of the human eIF4E-eIF4G complex
Descriptor: 7-METHYL-GUANOSINE-5'-TRIPHOSPHATE, Eukaryotic translation initiation factor 4 gamma 1, Eukaryotic translation initiation factor 4E, ...
Authors:Gruener, S, Peter, D, Weber, R, Wohlbold, L, Chung, M.-Y, Weichenrieder, O, Valkov, E, Igreja, C, Izaurralde, E.
Deposit date:2016-08-29
Release date:2016-10-26
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.53 Å)
Cite:The Structures of eIF4E-eIF4G Complexes Reveal an Extended Interface to Regulate Translation Initiation.
Mol.Cell, 64, 2016
5T48
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BU of 5t48 by Molmil
Crystal structure of the D. melanogaster eIF4E-eIF4G complex without lateral contact
Descriptor: 7-METHYL-GUANOSINE-5'-TRIPHOSPHATE, Eukaryotic translation initiation factor 4E, Eukaryotic translation initiation factor 4G, ...
Authors:Gruener, S, Peter, D, Weber, R, Wohlbold, L, Chung, M.-Y, Weichenrieder, O, Valkov, E, Igreja, C, Izaurralde, E.
Deposit date:2016-08-29
Release date:2016-10-26
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.19 Å)
Cite:The Structures of eIF4E-eIF4G Complexes Reveal an Extended Interface to Regulate Translation Initiation.
Mol.Cell, 64, 2016
6S8R
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BU of 6s8r by Molmil
D. melanogaster RNA helicase Me31B in complex with GIGYF
Descriptor: ACETATE ION, ATP-dependent RNA helicase me31b, GIGYF family protein CG11148
Authors:Peter, D, Valkov, E.
Deposit date:2019-07-10
Release date:2019-09-04
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.41 Å)
Cite:Molecular basis for GIGYF-Me31B complex assembly in 4EHP-mediated translational repression.
Genes Dev., 33, 2019
6S8S
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BU of 6s8s by Molmil
Extended structure of the human DDX6 C-terminal domain in complex with an EDC3 FDF peptide
Descriptor: 3-CYCLOHEXYL-1-PROPYLSULFONIC ACID, Enhancer of mRNA-decapping protein 3, PHOSPHATE ION, ...
Authors:Peter, D, Valkov, E.
Deposit date:2019-07-10
Release date:2019-09-04
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.21 Å)
Cite:Molecular basis for GIGYF-Me31B complex assembly in 4EHP-mediated translational repression.
Genes Dev., 33, 2019
5FU7
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BU of 5fu7 by Molmil
drosophila nanos NBR peptide bound to the NOT module of the human CCR4-NOT complex
Descriptor: CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 1, CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 2, CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 3, ...
Authors:Raisch, T, Bhandari, D, Sabath, K, Helms, S, Valkov, E, Weichenrieder, O, Izaurralde, E.
Deposit date:2016-01-21
Release date:2016-03-23
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Distinct Modes of Recruitment of the Ccr4-not Complex by Drosophila and Vertebrate Nanos
Embo J., 35, 2016
5FU6
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BU of 5fu6 by Molmil
NOT module of the human CCR4-NOT complex (Crystallization mutant)
Descriptor: CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 1, CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 2, CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 3
Authors:Raisch, T, Bhandari, D, Sabath, K, Helms, S, Valkov, E, Weichenrieder, O, Izaurralde, E.
Deposit date:2016-01-21
Release date:2016-03-23
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Distinct Modes of Recruitment of the Ccr4-not Complex by Drosophila and Vertebrate Nanos
Embo J., 35, 2016
4LJ0
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BU of 4lj0 by Molmil
Nab2 Zn fingers complexed with polyadenosine
Descriptor: ACETATE ION, MAGNESIUM ION, Nab2, ...
Authors:Stewart, M, Kuhlmann, S.I, Valkov, E.
Deposit date:2013-07-04
Release date:2013-10-09
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Structural basis for the molecular recognition of polyadenosine RNA by Nab2 Zn fingers.
Nucleic Acids Res., 42, 2014
6FC2
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BU of 6fc2 by Molmil
Crystal structure of the eIF4E-Eap1p complex from Saccharomyces cerevisiae
Descriptor: CALCIUM ION, Eukaryotic translation initiation factor 4E, Protein EAP1
Authors:Gruener, S, Valkov, E.
Deposit date:2017-12-20
Release date:2018-06-27
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.92 Å)
Cite:Structural motifs in eIF4G and 4E-BPs modulate their binding to eIF4E to regulate translation initiation in yeast.
Nucleic Acids Res., 46, 2018
6FBZ
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BU of 6fbz by Molmil
Crystal structure of the eIF4E-eIF4G complex from Chaetomium thermophilum in the cap-bound state
Descriptor: 7-METHYL-GUANOSINE-5'-TRIPHOSPHATE, Eukaryotic translation initiation factor 4E-like protein,Eukaryotic translation initiation factor 4E-like protein, Eukaryotic translation initiation factor 4G
Authors:Gruener, S, Valkov, E.
Deposit date:2017-12-20
Release date:2018-06-27
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.496 Å)
Cite:Structural motifs in eIF4G and 4E-BPs modulate their binding to eIF4E to regulate translation initiation in yeast.
Nucleic Acids Res., 46, 2018

 

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