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4PBD
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BU of 4pbd by Molmil
Crystal structure of the N-terminal CS domain of human Shq1
Descriptor: Protein SHQ1 homolog
Authors:Singh, M, Wang, Z, Cascio, D, Feigon, J.
Deposit date:2014-04-12
Release date:2015-01-14
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.68 Å)
Cite:Structure and Interactions of the CS Domain of Human H/ACA RNP Assembly Protein Shq1.
J.Mol.Biol., 427, 2015
4PCK
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BU of 4pck by Molmil
Crystal structure of the P22S mutant of N-terminal CS domain of human Shq1
Descriptor: GLYCEROL, Protein SHQ1 homolog
Authors:Singh, M, Wang, Z, Cascio, D, Feigon, J.
Deposit date:2014-04-15
Release date:2015-01-14
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.401 Å)
Cite:Structure and Interactions of the CS Domain of Human H/ACA RNP Assembly Protein Shq1.
J.Mol.Biol., 427, 2015
2GRC
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BU of 2grc by Molmil
1.5 A structure of bromodomain from human BRG1 protein, a central ATPase of SWI/SNF remodeling complex
Descriptor: Probable global transcription activator SNF2L4
Authors:Singh, M, Popowicz, G.M, Krajewski, M, Holak, T.A.
Deposit date:2006-04-24
Release date:2007-05-08
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Structural ramification for acetyl-lysine recognition by the bromodomain of human BRG1 protein, a central ATPase of the SWI/SNF remodeling complex.
Chembiochem, 8, 2007
3EUD
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BU of 3eud by Molmil
Structure of the CS domain of the essential H/ACA RNP assembly protein Shq1p
Descriptor: Protein SHQ1
Authors:Singh, M, Cascio, D, Gonzales, F.A, Heckmann, N, Chanfreau, G, Feigon, J.
Deposit date:2008-10-09
Release date:2008-11-18
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structure and Functional Studies of the CS Domain of the Essential H/ACA Ribonucleoparticle Assembly Protein SHQ1.
J.Biol.Chem., 284, 2009
4ERD
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BU of 4erd by Molmil
Crystal structure of the C-terminal domain of Tetrahymena telomerase protein p65 in complex with stem IV of telomerase RNA
Descriptor: 5'-R(P*GP*GP*UP*CP*GP*AP*CP*AP*UP*CP*UP*UP*CP*GP*GP*AP*UP*GP*GP*AP*CP*C)-3', POTASSIUM ION, Telomerase associated protein p65
Authors:Singh, M, Wang, Z, Koo, B.-K, Patel, A, Cascio, D, Collins, K, Feigon, J.
Deposit date:2012-04-19
Release date:2012-06-20
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (2.589 Å)
Cite:Structural Basis for Telomerase RNA Recognition and RNP Assembly by the Holoenzyme La Family Protein p65.
Mol.Cell, 47, 2012
4EYT
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BU of 4eyt by Molmil
Crystal structure of the C-terminal domain of Tetrahymena telomerase protein p65
Descriptor: SULFATE ION, Telomerase associated protein p65
Authors:Singh, M, Wang, Z, Koo, B.-K, Patel, A, Cascio, D, Collins, K, Feigon, J.
Deposit date:2012-05-01
Release date:2012-06-20
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural Basis for Telomerase RNA Recognition and RNP Assembly by the Holoenzyme La Family Protein p65.
Mol.Cell, 47, 2012
4I14
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BU of 4i14 by Molmil
Crystal Structure of Mtb-ribA2 (Rv1415)
Descriptor: Riboflavin biosynthesis protein RibBA, SULFATE ION, ZINC ION
Authors:Singh, M, Kumar, P, Yadav, S, Gautam, R, Sharma, N, Karthikeyan, S.
Deposit date:2012-11-20
Release date:2013-08-28
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (3 Å)
Cite:The crystal structure reveals the molecular mechanism of bifunctional 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II (Rv1415) from Mycobacterium tuberculosis
Acta Crystallogr.,Sect.D, 69, 2013
2LSL
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BU of 2lsl by Molmil
Solution structure of the C-terminal domain of Tetrahymena telomerase protein p65
Descriptor: Telomerase associated protein p65
Authors:Singh, M, Wang, Z, Koo, B, Patel, A, Cascio, D, Collins, K, Feigon, J.
Deposit date:2012-05-01
Release date:2012-06-20
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Structural Basis for Telomerase RNA Recognition and RNP Assembly by the Holoenzyme La Family Protein p65.
Mol.Cell, 47, 2012
3MGZ
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BU of 3mgz by Molmil
Crystal structure of DHBPS domain of bi-functional DHBPS/GTP cyclohydrolase II from Mycobacterium tuberculosis at pH 4.0
Descriptor: 3,4-dihydroxy-2-butanone 4-phosphate synthase, SULFATE ION
Authors:Singh, M, Kumar, P, Karthikeyan, S.
Deposit date:2010-04-07
Release date:2011-02-23
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.07 Å)
Cite:Structural basis for pH dependent monomer-dimer transition of 3,4-dihydroxy 2-butanone-4-phosphate synthase domain from Mycobacterium tuberculosis
J.Struct.Biol., 174, 2011
3MIO
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BU of 3mio by Molmil
Crystal structure of 3,4-dihydroxy-2-butanone 4-phosphate synthase domain from Mycobacterium tuberculosis at pH 6.00
Descriptor: 3,4-dihydroxy-2-butanone 4-phosphate synthase, GLYCEROL, PHOSPHATE ION, ...
Authors:Singh, M, Karthikeyan, S.
Deposit date:2010-04-11
Release date:2011-02-23
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural basis for pH dependent monomer-dimer transition of 3,4-dihydroxy 2-butanone-4-phosphate synthase domain from Mycobacterium tuberculosis
J.Struct.Biol., 174, 2011
3MK5
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BU of 3mk5 by Molmil
Crystal structure of 3,4-dihydroxy-2-butanone 4-phosphate synthase domain from Mycobacterium tuberculosis with sulfate and zinc at pH 4.00
Descriptor: 3,4-dihydroxy-2-butanone 4-phosphate synthase, SULFATE ION, ZINC ION
Authors:Singh, M, Karthikeyan, S.
Deposit date:2010-04-14
Release date:2011-02-23
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.06 Å)
Cite:Structural basis for pH dependent monomer-dimer transition of 3,4-dihydroxy 2-butanone-4-phosphate synthase domain from Mycobacterium tuberculosis
J.Struct.Biol., 174, 2011
2MNW
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BU of 2mnw by Molmil
Solution structure of the P22S mutant of N-terminal CS domain of human Shq1
Descriptor: Protein SHQ1 homolog
Authors:Singh, M, Wang, Z, Cascio, D, Feigon, J.
Deposit date:2014-04-16
Release date:2015-01-14
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Structure and Interactions of the CS Domain of Human H/ACA RNP Assembly Protein Shq1.
J.Mol.Biol., 427, 2015
4KM6
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BU of 4km6 by Molmil
Human folate receptor alpha (FOLR1) at acidic pH, orthorhombic form
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Folate receptor alpha
Authors:Singh, M, Dann III, C.E.
Deposit date:2013-05-08
Release date:2013-08-07
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Structures of human folate receptors reveal biological trafficking states and diversity in folate and antifolate recognition.
Proc.Natl.Acad.Sci.USA, 110, 2013
4G1P
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BU of 4g1p by Molmil
Structural and Mechanistic Basis of Substrate Recognition by Novel Di-peptidase Dug1p From Saccharomyces cerevisiae
Descriptor: CYSTEINE, Cys-Gly metallodipeptidase DUG1, GLYCINE, ...
Authors:Singh, A.K, Singh, M, Pandya, V.K, Singh, V, Mittal, M, Kumaran, S.
Deposit date:2012-07-11
Release date:2013-07-17
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.547 Å)
Cite:Structural and Mechanistic Basis of Substrate Recognition by Novel Di-peptidase Dug1p From Saccromyces cerevesiae
To be published
7WU8
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BU of 7wu8 by Molmil
Crystal structure of Harmonin-homology domain 2 (HHD2) of human RTEL1
Descriptor: Regulator of telomere elongation helicase 1
Authors:Kumar, N, Rothweiler, U, Singh, M.
Deposit date:2022-02-07
Release date:2023-08-09
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.599 Å)
Cite:Harmonin homology domain-mediated interaction of RTEL1 helicase with RPA and DNA provides insights into its recruitment to DNA repair sites.
Nucleic Acids Res., 52, 2024
8GAP
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BU of 8gap by Molmil
Structure of LARP7 protein p65-telomerase RNA complex in telomerase
Descriptor: Telomerase La-related protein p65, Telomerase RNA, Telomerase associated protein p50, ...
Authors:Wang, Y, He, Y, Wang, Y, Yang, Y, Singh, M, Eichhorn, C.D, Zhou, Z.H, Feigon, J.
Deposit date:2023-02-23
Release date:2023-06-28
Last modified:2023-07-19
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Structure of LARP7 Protein p65-telomerase RNA Complex in Telomerase Revealed by Cryo-EM and NMR.
J.Mol.Biol., 435, 2023
2WBC
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BU of 2wbc by Molmil
REFINED CRYSTAL STRUCTURE (2.3 ANGSTROM) OF A WINGED BEAN CHYMOTRYPSIN INHIBITOR AND LOCATION OF ITS SECOND REACTIVE SITE
Descriptor: CHYMOTRYPSIN INHIBITOR
Authors:Dattagupta, J.K, Podder, A, Chakrabarti, C, Sen, U, Mukhopadhyay, D, Dutta, S.K, Singh, M.
Deposit date:1997-11-26
Release date:1998-02-25
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Refined crystal structure (2.3 A) of a double-headed winged bean alpha-chymotrypsin inhibitor and location of its second reactive site.
Proteins, 35, 1999
1Y25
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BU of 1y25 by Molmil
structure of mycobacterial thiol peroxidase Tpx
Descriptor: ACETATE ION, Probable thiol peroxidase
Authors:Stehr, M, Hoffmann, B, Jger, T, Singh, M, Hecht, H.J.
Deposit date:2004-11-20
Release date:2005-11-20
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structure of the inactive variant C60S of Mycobacterium tuberculosis thiol peroxidase
Acta Crystallogr.,Sect.D, 62, 2006
6KMQ
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BU of 6kmq by Molmil
2.3 Angstrom resolution structure of dimeric HigBA toxin-antitoxin complex from E. coli
Descriptor: Antitoxin HigA, mRNA interferase toxin HigB
Authors:Jadhav, P, Sinha, V.K, Rothweiler, U, Singh, M.
Deposit date:2019-07-31
Release date:2020-11-18
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:2.09 angstrom Resolution structure of E. coli HigBA toxin-antitoxin complex reveals an ordered DNA-binding domain and intrinsic dynamics in antitoxin.
Biochem.J., 477, 2020
6KML
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BU of 6kml by Molmil
2.09 Angstrom resolution crystal structure of tetrameric HigBA toxin-antitoxin complex from E.coli
Descriptor: Antitoxin HigA, mRNA interferase toxin HigB
Authors:Jadhav, P, Sinha, V.K, Rothweiler, U, Singh, M.
Deposit date:2019-07-31
Release date:2020-11-18
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.095 Å)
Cite:2.09 angstrom Resolution structure of E. coli HigBA toxin-antitoxin complex reveals an ordered DNA-binding domain and intrinsic dynamics in antitoxin.
Biochem.J., 477, 2020
7D8O
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BU of 7d8o by Molmil
Crystal structure of E. coli ToxIN type III toxin-antitoxin complex
Descriptor: Antitoxin RNA, Type III toxin-antitoxin system ToxN/AbiQ family toxin
Authors:Manikandan, P, Rothweiler, U, Singh, M.
Deposit date:2020-10-08
Release date:2022-01-05
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.097 Å)
Cite:Identification, functional characterization, assembly and structure of ToxIN type III toxin-antitoxin complex from E. coli.
Nucleic Acids Res., 50, 2022
1G2C
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BU of 1g2c by Molmil
HUMAN RESPIRATORY SYNCYTIAL VIRUS FUSION PROTEIN CORE
Descriptor: FUSION PROTEIN (F)
Authors:Zhao, X, Singh, M, Malashkevich, V.N, Kim, P.S.
Deposit date:2000-10-18
Release date:2001-01-03
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural characterization of the human respiratory syncytial virus fusion protein core.
Proc.Natl.Acad.Sci.USA, 97, 2000
1ZKZ
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BU of 1zkz by Molmil
Crystal Structure of BMP9
Descriptor: Growth/differentiation factor 2
Authors:Brown, M.A, Zhao, Q, Baker, K.A, Naik, C, Chen, C, Pukac, L, Singh, M, Tsareva, T, Parice, Y, Mahoney, A, Roschke, V, Sanyal, I, Choe, S.
Deposit date:2005-05-04
Release date:2005-05-24
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.33 Å)
Cite:Crystal structure of BMP-9 and functional interactions with pro-region and receptors
J.Biol.Chem., 280, 2005
1JEK
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BU of 1jek by Molmil
Visna TM CORE STRUCTURE
Descriptor: ENV POLYPROTEIN
Authors:Malashkevich, V.N, Singh, M, Kim, P.S.
Deposit date:2001-06-18
Release date:2001-07-25
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:The trimer-of-hairpins motif in membrane fusion: Visna virus.
Proc.Natl.Acad.Sci.USA, 98, 2001
7YL9
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BU of 7yl9 by Molmil
Cryo-EM structure of complete transmembrane channel E289A mutant Vibrio cholerae Cytolysin
Descriptor: Hemolysin
Authors:Mondal, A.K, Sengupta, N, Singh, M, Biswas, R, Lata, K, Lahiri, I, Dutta, S, Chattopadhyay, K.
Deposit date:2022-07-25
Release date:2022-08-31
Method:ELECTRON MICROSCOPY (4.7 Å)
Cite:Cryo-EM structure of complete transmembrane channel E289A mutant Vibrio cholerae Cytolysin
J.Biol.Chem.

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